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Search Results: 1 - 10 of 11285 matches for " Carmen Neumann "
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Improving the Dietary Protein Quality by Amino Acid Fortification with a High Inclusion Level of Micro Algae (Spirulina platensis) or Insect Meal (Hermetia illucens) in Meat Type Chicken Diets  [PDF]
Carmen Neumann, Susanne Velten, Frank Liebert
Open Journal of Animal Sciences (OJAS) , 2018, DOI: 10.4236/ojas.2018.81002
Abstract: The objective of this study was to measure protein quality parameters (PPV, NPU and NPUstd) of chicken diets with complete substitution of soybean meal (SBM) by Spirulina meal (SM) or partly defatted Hermetia meal (HM). N balance experiments were based on the quantitative excreta collection method, divided into starter period (10 - 20 d) and grower period (25 - 35 d). The study utilized 70 all male meat type chicken (Ross 308). Data assessment applied the exponential N utilization model of the “Goettingen approach”. The control diet was based on wheat, corn and SBM. In four experimental diets SBM was completely substituted by SM or HM, but fortified with feed amino acids (AA) both on a basic level of supplementation (Lys and Met added equal to the control diet) and on an extended level (Lys, Met, Thr, Arg, Val, Ile, His added). At a basic level of AA supplementation, complete replacement of SBM by SM or HM in chicken diets depressed dietary protein quality significantly (p < 0.05). However, the extended level of AA supplementation improved protein quality parameters of the diets with both of the alternative proteins significantly (p < 0.05), but still generally not on par with the control diet. The observed responses were accentuated when the well-known effect of N intake on protein utilization was eliminated through the standardization of N intake by application of the “Goettingen approach”.
The Graded Inclusion of Algae (Spirulina platensis) or Insect (Hermetia illucens) Meal as a Soybean Meal Substitute in Meat Type Chicken Diets Impacts on Growth, Nutrient Deposition and Dietary Protein Quality Depending on the Extent of Amino Acid Supplementation  [PDF]
Carmen Neumann, Susanne Velten, Frank Liebert
Open Journal of Animal Sciences (OJAS) , 2018, DOI: 10.4236/ojas.2018.82012
Abstract: Three consecutive growth experiments were conducted to evaluate growth performance, whole body analyses and protein quality parameters from chicken diets with 50%, 75% and 100% substitution of soybean meal (SBM) by Spirulina meal (SM) or partly defatted Hermetia meal (HM). Each of the experiments was divided into a starter period (1 - 21 d) and a grower period (22 - 34 d). One-day-old male growing chickens (Ross 308) were randomly allotted to 48 floor pens making use of 6 birds/pen (Exp.1) or 7 birds/pen (Exp. 2, 3), and the experiments included a control diet (n = 12) and four experimental diets (n = 9). Experiment 1 examined a 50 % replacement of SBM by the alternative proteins under study, both on a basic and an advanced level of amino acid (AA) fortification to meet the recommended ideal amino acid ratio (IAAR). In experiment 2, 75% (starter diet) and 50% (grower diet) replacement of SBM was investigated. Experiment 3 investigated the effects of complete SBM substitution by SM or HM in starter and grower diets. In the second and third experiment diets with both of the alternative proteins and the control diet were AA supplemented to meet the current IAAR. In a further step, the calculated first limiting AA (LAA) was reduced to 80% of its requirement recommendation to allow for further evaluation of the individual AA efficiency according to the Goettingen approach. Different levels (50%, 75%, or 100%) of replacing SBM by HM or SM in chicken diets depressed dietary protein quality (p <
Effects of the Partial Replacement of Soybean Meal by Insect or Algae Meal in Chicken Diets with Graded Amino Acid Supply on Parameters of Gut Microbiology and Dietary Protein Quality  [PDF]
Susanne Velten, Carmen Neumann, Jenny Sch?fer, Frank Liebert
Open Journal of Animal Sciences (OJAS) , 2018, DOI: 10.4236/ojas.2018.83020
Abstract: Insects or algae are considered future solutions to substitute imported feed proteins like soybean meal (SBM) in animal nutrition. The objective of this research, as part of the multidisciplinary project “Sustainability transitions”, focused on replacing 50% SBM by partly defatted larvae meal from black soldier flies (Hermetia illucens) or the blue-green algae Spirulina platensis in meat type chicken diets. The current study aimed to evaluate the effects on body composition, protein quality, apparent precaecal digestibility (apcD) and parameters of intestinal microbiota. In total, 288 one-day-old male growing chickens (Ross 308) from a commercial hatchery were randomly allotted to 48 pens (6 birds per pen) across five diets, which were fed at a free choice level. The control diet utilized SBM, wheat and corn as main ingredients, and experimental diets replaced 50% of SBM by the alternative proteins under study. Amino acid (AA) supplementation of the final diets was conducted both at a basic level (diets HM, SM; Lys and Met added equal to the control diet) and an extended level of AA fortification (diets HM+, SM+; extended supplementation of Lys, Met, Thr, Arg). After finishing the growth study, 4 individual birds per diet were slaughtered for whole body analyses to derive nutrient utilization and dietary protein quality parameters. Additionally, pooled chyme samples from 16 birds per diet (control, HM and SM) were analyzed to assess apcD and microbial parameters. Diets HM and SM with a basic level of AA fortification led to significant depressions in nutrient deposition and dietary protein quality. However, HM+ and SM+ diets with an extended level of AA supplementation led to significantly improved responses; however these were still generally not on par with the control diet. The HM+ diet provided superior CP deposition and dietary protein quality, as compared to the SM+ diet, but equal to the control diet. Results of gut microbiology yielded no significant effects due to feeding the alternative protein sources under study.
Effects of 50 Percent Substitution of Soybean Meal by Alternative Proteins from Hermetia illucens or Spirulina platensis in Meat-Type Chicken Diets with Graded Amino Acid Supply  [PDF]
Susanne Velten, Carmen Neumann, Martina Bleyer, Eva Gruber-Dujardin, Maria Hanuszewska, Barbara Przybylska-Gornowicz, Frank Liebert
Open Journal of Animal Sciences (OJAS) , 2018, DOI: 10.4236/ojas.2018.82009
Abstract: Alternative protein sources, such as insects or algae meals are in special focus of animal nutrition in order to replace soybean meal (SBM). As part of the multidisciplinary project “sustainability transitions” this study evaluated effects of replacing SBM by partly defatted larvae meal from the black soldier fly, Hermetia illucens or meal from the micro algae Spirulina platensis in broiler diets. The aim of the current study was to investigate the chickens growth performance and the intestinal morphology as well as the health status. 288 one-day-old male growing chickens (Ross 308) from a commercial hatchery were randomly allotted to 48 pens (6 birds per pen) for the growth study with five diets and feed supply on free choice level. The control diet was based on wheat, corn and SBM. The experimental diets replaced 50% of SBM by the alternative proteins under study, both on a basic level of amino acid (AA) supplementation (Lys and Met added equal to the control diet) (diet HM and SM) and an extended level of AA fortification (Lys, Met, Thr, Arg, Val added) (diet HM+ and SM+). Response of chickens was evaluated by zoo-technical parameters, which were under weekly control (e.g. growth, feed intake, feed conversion ratio, mortality). After finishing the growth study birds from control and the experimental diets at the basic level of AA supplementation were slaughtered after 12 hour fastening and utilized for gut morphometric analysis and histological evaluation of the health status. Diets at a basic level of AA fortification led to significant depression of growth, feed intake, feed conversion ratio, and protein conversion ratio, respectively. In addition, the acceptance of the Spirulina diet was lower (p 0.001) as compared to the Hermetia based diet.
microRNA-122 Dependent Binding of Ago2 Protein to Hepatitis C Virus RNA Is Associated with Enhanced RNA Stability and Translation Stimulation
K. Dominik Conrad, Florian Giering, Corinna Erfurth, Angelina Neumann, Carmen Fehr, Gunter Meister, Michael Niepmann
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0056272
Abstract: Translation of Hepatitis C Virus (HCV) RNA is directed by an internal ribosome entry site (IRES) in the 5′-untranslated region (5′-UTR). HCV translation is stimulated by the liver-specific microRNA-122 (miR-122) that binds to two binding sites between the stem-loops I and II near the 5′-end of the 5′-UTR. Here, we show that Argonaute (Ago) 2 protein binds to the HCV 5′-UTR in a miR-122-dependent manner, whereas the HCV 3′-UTR does not bind Ago2. miR-122 also recruits Ago1 to the HCV 5’-UTR. Only miRNA duplex precursors of the correct length stimulate HCV translation, indicating that the duplex miR-122 precursors are unwound by a complex that measures their length. Insertions in the 5′-UTR between the miR-122 binding sites and the IRES only slightly decrease translation stimulation by miR-122. In contrast, partially masking the miR-122 binding sites in a stem-loop structure impairs Ago2 binding and translation stimulation by miR-122. In an RNA decay assay, also miR-122-mediated RNA stability contributes to HCV translation stimulation. These results suggest that Ago2 protein is directly involved in loading miR-122 to the HCV RNA and mediating RNA stability and translation stimulation.
Personality of Students of Economics, Medicine, and Verbal Communication: Preliminary Results  [PDF]
J. Richter, R. Neumann
Psychology (PSYCH) , 2011, DOI: 10.4236/psych.2011.23039
Abstract: Differences on personality between students of economics, medicine and verbal communication should be explored by means of the Temperament and Character Inventory. Students of economics are mainly characterized by lower harm avoidance and lower reward dependence and higher self directedness than medical students and students of verbal communication. Students of all groups seem to overestimate their self-directedness with economical students showing the most pronounced tendency of overrating, whereas medical students tend to overrate their cooperativeness more than the students from the other groups. The obvious disturbed self-evaluation corresponds to the students’ professional orientation. The students can be characterized by specific and varying types and impact of social desirability depending on their professional career.
Lattice Boltzmann Simulations in the Slip and Transition Flow Regime with the Peano Framework  [PDF]
Philipp Neumann, Till Rohrmann
Open Journal of Fluid Dynamics (OJFD) , 2012, DOI: 10.4236/ojfd.2012.23010
Abstract: We present simulation results of flows in the finite Knudsen range, that is in the slip and transition flow regime. Our implementations are based on the Lattice Boltzmann method and are accomplished within the Peano framework. We validate our code by solving two- and three-dimensional channel flow problems and compare our results with respective experiments from other research groups. We further apply our Lattice Boltzmann solver to the geometrical setup of a microreactor consisting of differently sized channels and a reactor chamber. Here, we apply static adaptive grids to further reduce computational costs. We further investigate the influence of using a simple BGK collision kernel in coarse grid regions which are further away from the slip boundaries. Our results are in good agreement with theory and non-adaptive simulations, demonstrating the validity and the capabilities of our adaptive simulation software for flow problems at finite Knudsen numbers.
Molecular Neuropathology of TDP-43 Proteinopathies
Manuela Neumann
International Journal of Molecular Sciences , 2009, DOI: 10.3390/ijms10010232
Abstract: The identification of TDP-43 as the major component of the pathologic inclusions in most forms of sporadic and familial frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) and amyotrophic lateral sclerosis (ALS) resolved a long-standing enigma concerning the nature of the ubiquitinated disease protein under these conditions. Anti-TDP-43 immunohistochemistry and the recent development of novel tools, such as phosphorylation-specific TDP-43 antibodies, have increased our knowledge about the spectrum of pathological changes associated with FTLD-U and ALS and moreover, facilitated the neuropathological routine diagnosis of these conditions. This review summarizes the recent advances in our understanding on the molecular neuropathology and pathobiology of TDP-43 in FTLD and ALS.
"Mientras volaban correos por los pueblos": autogoverno e práticas letradas nas miss?es Guarani - século XVII
Neumann, Eduardo;
Horizontes Antropológicos , 2004, DOI: 10.1590/S0104-71832004000200005
Abstract: in the middle xviiith century, the "tratado de madrid" (1750) took place between portugal and spain. both countries were looking forward to define the new southern latin america frontier. the tratado de madrid had a strongly impact over the indians communities under jesuits influence, starting colonial rebellion named guaranitc war (1754-1756). during this period an intense communication by mail between the spanish authorities, priests and the guarani was noticed. the "indios principais" - the missions writing elite - expressed their opinion writing letters in the way to cancel the tratado de madrid. the different kinds of documents produced by the insurgent guaranis letters, notes and messages- let us to rethink the relation between the indians and the writing culture. it also indicates the lack of attention in the historical debate to the native point of view expressed by writing.
Vom Nachthunger“ und n chtlichen Zyn “. Die Darstellung ehelicher Sexualit t in Valentin Schumanns Nachtbüchlein I/II.
Franziska Neumann
AEON : Forum für Junge Geschichtswissenschaft , 2009,
Abstract: Die Schwanksammlungen des 16. Jahrhunderts sind gemeinhin für ihre obsz nen und unfl tigen Darstellungen des Sexuellen bekannt. Jedoch, so die These des Aufsatzes, l sst sich daraus keine generelle Unbefangenheit gegenüber K rperlichkeit und Sexualit t schlussfolgern. Vielmehr folgen die frivolen Geschichten einer spezifischen Vorstellung von Sexualit t, die auf der Interdependenz partnerschaftlichen Handelns ausgerichtet ist. Die k rperliche Beziehung der Ehepartner wird als grundlegender Teil des ehelichen Miteinanders verstanden. Diese Wahrnehmung wird exemplarisch in Valentin Schumanns Nachtbüchlein I und II (1559) herausgearbeitet.
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