oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 157 )

2018 ( 172 )

2017 ( 151 )

2016 ( 204 )

Custom range...

Search Results: 1 - 10 of 97794 matches for " Carmen I; "
All listed articles are free for downloading (OA Articles)
Page 1 /97794
Display every page Item
Manejo actual en síndrome de Pierre Robin
Morovic I,Carmen Gloria;
Revista chilena de pediatría , 2004, DOI: 10.4067/S0370-41062004000100005
Abstract: introduction: airway obstruction in children with pierre robin syndrome (prs)could be an important determinant of the prognosis and quality of life of the child. objective: to analyze mandibular distraction as an early management in children with prs and airway obstruction. method: prs patients treated between january 1998 and march 2003 at the luis calvo mackenna hospital were included. clinical evaluation, lateral cephalograms, nasoendoscopy, oxygen saturation and polysomnograms were used as parameters in the decision to perform mandibular distraction. long term follow up included evaluation of complications, nutritional evolution, facial growth and development. results: 23/31 prs patients underwent mandibular distraction, relieving airway obstruction in all the cases. 2 cases underwent tracheotomy at birth that were removed during the process. 2 patients had pulmonary hypertension and reversed clinical signs after distraction. their weight charts improved significantly after the operation. conclusion: mandibular distraction is a successful method for young patients with prs to relieve airway onstruction, improve feeding and avoid tracheotomy or early decannulation in previously tracheotomized patients
Cirugía de mano en pediatría
Carmen Gloria Morovic I.
Revista chilena de pediatría , 2005,
Abstract:
Manejo actual en síndrome de Pierre Robin Current management of Pierre Robin syndrome
Carmen Gloria Morovic I
Revista chilena de pediatría , 2004,
Abstract: Introducción: La dificultad respiratoria del síndrome Pierre Robin (SPR) puede ser determinante en su pronóstico y calidad de vida. Este estudio evalúa la eficacia de la distracción mandibular como tratamiento precoz en PRS con dificultad respiratoria severa. Pacientes y Método: Lactantes SPR controlados en Unidad Cirugía Plástica Hospital Luis Calvo Mackenna entre enero 1998 y marzo 2003. La indicación de distracción se basa en evaluación clínica, radiología, nasofibroscopía, saturación de oxígeno y/o polisomnografía. El seguimiento tardío evalúa complicaciones, evolución nutricional, crecimiento y desarrollo facial. Resultados: 23/31 lactantes SPR se les realizó distracción mandibular, presentando 100% alivio de sintomatología obstructiva. Dos casos presentaban traqueotomía desde RN, que se retiraron durante el procedimiento. Dos casos presentaban hipertensión pulmonar que revirtieron post distracción. Hubo mejoría significativa de las curvas de crecimiento ponderal. Conclusión: La distracción mandibular es un método efectivo en lactantes con micrognatia, aliviando la obstrucción respiratoria, facilitando alimentación, evitando raqueotomías y/o permitiendo decanulación precoz Introduction: Airway obstruction in children with Pierre Robin syndrome (PRS)could be an important determinant of the prognosis and quality of life of the child. Objective: to analyze mandibular distraction as an early management in children with PRS and airway obstruction. Method: PRS patients treated between January 1998 and March 2003 at the Luis Calvo Mackenna Hospital were included. Clinical evaluation, lateral cephalograms, nasoendoscopy, oxygen saturation and polysomnograms were used as parameters in the decision to perform mandibular distraction. Long term follow up included evaluation of complications, nutritional evolution, facial growth and development. Results: 23/31 PRS patients underwent mandibular distraction, relieving airway obstruction in all the cases. 2 cases underwent tracheotomy at birth that were removed during the process. 2 patients had pulmonary hypertension and reversed clinical signs after distraction. Their weight charts improved significantly after the operation. Conclusion: Mandibular distraction is a successful method for young patients with PRS to relieve airway onstruction, improve feeding and avoid tracheotomy or early decannulation in previously tracheotomized patients
Successful Pathways To The Teaching Profession For Puerto Ricans
Carmen I. Mercado
Centro Journal , 2011,
Abstract: This article makes program and policy recommendations for the design of effective pathways to teaching careers for Puerto Ricans that combine college readiness with workforce development in sectors where there are opportunities for entry-level employment with minimal credentials and opportunity for advancement at a salary above the minimum wage. The pathways target vulnerable members of the Puerto Rican community, such as young males, ages 16 to 24, who are in high school, unemployed, or employed in low-wage industries.
Poling effect on distribution of quenched random fields in a uniaxial relaxor ferroelectric
Manuel I. Marques,Carmen Arago
Physics , 2006, DOI: 10.1209/epl/i2005-10056-8
Abstract: The frequency dependence of the dielectric permitivity's maximum has been studied for poled and unpoled doped relaxor strontium barium niobate $Sr_{0.61}Ba_{0.39}Nb_{2}O_{6}:Cr^{3+}$ (SBN-61:Cr). In both cases the maximum found is broad and the frequency dispersion is strong. The present view of random fields compensation in the unpoled sample is not suitable for explaining this experimental result. We propose a new mechanism where the dispersion of quenched random electric fields, affecting the nanodomains, is minimized after poling. We test our proposal by numerical simulations on a random field Ising model. Results obtained are in agreement with the polarization's measurements presented by Granzow et al. [Phys. Rev. Lett {\bf 92}, 065701 (2004)].
Glycogen Synthase Kinase 3 Inhibitors in the Next Horizon for Alzheimer's Disease Treatment
Ana Martinez,Carmen Gil,Daniel I. Perez
International Journal of Alzheimer's Disease , 2011, DOI: 10.4061/2011/280502
Abstract: Glycogen synthase kinase 3 (GSK-3), a proline/serine protein kinase ubiquitously expressed and involved in many cellular signaling pathways, plays a key role in the pathogenesis of Alzheimer's disease (AD) being probably the link between β-amyloid and tau pathology. A great effort has recently been done in the discovery and development of different new molecules, of synthetic and natural origin, able to inhibit this enzyme, and several kinetics mechanisms of binding have been described. The small molecule called tideglusib belonging to the thiadiazolidindione family is currently on phase IIb clinical trials for AD. The potential risks and benefits of this new kind of disease modifying drugs for the future therapy of AD are discussed in this paper. 1. Introduction After more than a century from its discovery and several decades of intensive research, the cause of Alzheimer’s disease (AD) remains yet unknown [1]. As a consequence, it is very difficult to discover and/or develop effective therapies. For this reason, current therapies are mostly palliative and there exists a significant unmet medical need in the treatment of this devastating condition. Different etiological hypotheses for AD origin have been considered in the last thirty years focused partially on the different histopathological lesions found in the brain of AD patients. The first one was the cholinergic hypothesis that considers the disease as a consequence of a deficit in the neurotransmitter acetylcholine. It is implicated in the cognitive process and consequently to its decline [2]. Although this strategy has severe limitations, drug research in this field has succeeded and today we have on the market four of the five drugs currently approved for the palliative treatment of AD based on drug research following this hypothesis [3]. The acetylcholinesterase inhibitors produced a slight enhancement in patient’s cognitive abilities that partially improve temporarily their quality of life, but, in fact, the neurodegenerative disease does not stop [4]. In the eighties the amyloid cascade hypothesis emerged, and it was the most long considered theory [5]. It is based on the β-amyloid overproduction as responsible for the senile plaque formation and for the neurotoxicity that leads to the progressive neuronal death. However, controversial data about if β-amyloid is the cause of the disease or one of the main risk factors for AD are reported [6]. This dilemma is more pronounced recently because of the phase III clinical trials failure of the compounds discovered and developed based on amyloid
Animal models of copper-associated liver disease
I Carmen Fuentealba, Enrique M Aburto
Comparative Hepatology , 2003, DOI: 10.1186/1476-5926-2-5
Abstract: Copper-associated diseases are increasingly being reported in both man and animals [1-6]. Wilson's disease is an autosomal recessive disorder that results from pathological accumulation of copper predominantly in the liver and brain [1]. Copper also has a role in fatal, non-Wilson's liver diseases affecting young children with a genetic abnormality of copper metabolism [3,7]. Excess accumulation of copper also occurs as a consequence of chronic liver diseases such as primary biliary cirrhosis, and chronic hepatitis in both humans [8] and animals [9]. A genetic defect similar to that of Wilson's disease has been discovered in the Long Evans Cinnamon (LEC) rat [10], and the toxic milk mouse [11]. Animal models play an important role in the study of copper homeostasis, mechanisms (pathogenesis) of copper-associated liver diseases, and in the implementation of new therapeutic approaches such as gene therapy [12].The proximal small intestine is recognized as the main site of dietary copper absorption in mammals [13]. Transport from the intestinal lumen into intestinal mucosa is a carrier-mediated process involving a saturable transport component [14]. The overall intestinal copper uptake is influenced by amino acids, ascorbic acid, and other dietary factors [14]. Once in mucosal cells, approximately 80% of the newly absorbed copper is in the cytosol, mainly bound to metallothioneins (MT). These are low-molecular weight inducible proteins with many functions including homeostasis, storage, transport and detoxification of metals [15,16]. Metallothioneins bind to many metals, but in normal circumstances only Zn, Cu and Cd binding is significant [17]. After passage through the enterocytes, copper enters the portal circulation where it is bound to carrier proteins (primarily albumin), peptides and amino acids and is transported to the liver [18], with lesser amounts entering the kidney [17].Copper transport in hepatocytes can be divided into three discernible but interrelated
Tendencia de la precipitación pluvial en Bramón, estado Táchira, Venezuela
Lozada García,Beatriz I; Barboza,Carmen;
Agronomía Tropical , 2007,
Abstract: the agriculture presents a high dependence of the climatic conditions. of those elements of the climate, the rainfall is the responsible for the alternation in the yields, due to its inter-year variability. in the last years had increased the interest for the studies of variability and climatic change, so it is necessary to have homogeneous series. the objective of this study was to identify tendencies or trends in the series of annual rainfall, and of the rainfall of the dry (december-march) and wet (april-november) periods in bramón (táchira state, venezuela), in the period from 1941 to 2005, and to estimate the year of beginning of the change in the tendency of the rainfall. the analysis of the tendency was done through the following not parametric tests: serial correlation (wald-wolfowitz), the coefficient of spearman, mann-kendall, and the test of pettit. a significant (α=0.05) increase of the annual total rainfall, and wet time was observed. the test of pettit showed a significant change (α=0.05) in the year 1965.
Presentació
Carmen Albadalejo,I?aki Echebarria Aranzabal
Temps d'Educació , 1997,
Abstract:
La divulgació científica. Entrevista amb Javier Tejada
Carmen Albadalejo,I?aki Echebarria Aranzabal
Temps d'Educació , 1997,
Abstract:
Page 1 /97794
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.