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Search Results: 1 - 10 of 226666 matches for " Carmen Elena; López "
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Air pollution and mortality in the Canary Islands: a time-series analysis
Elena López-Villarrubia, Ferran Ballester, Carmen I?iguez, Nieves Peral
Environmental Health , 2010, DOI: 10.1186/1476-069x-9-8
Abstract: From 2000 to 2004, the relationship between daily changes in PM10, PM2.5, SO2, NO2, CO, and ozone levels and daily total mortality and mortality due to respiratory and heart diseases were assessed using Generalized Additive Poisson models controlled for potential confounders. The lag effect (up to five days) as well as the concurrent and previous day averages and distributed lag models were all estimated. Single and two pollutant models were also constructed.Daily levels of PM10, PM2.5, NO2, and SO2 were found to be associated with an increase in respiratory mortality in Santa Cruz de Tenerife and with increased heart disease mortality in Las Palmas de Gran Canaria, thus indicating an association between daily ozone levels and mortality from heart diseases. The effects spread over five successive days. SO2 was the only air pollutant significantly related with total mortality (lag 0).There is a short-term association between current exposure levels to air pollution and mortality (total as well as that due specifically to heart and respiratory diseases) in both cities. Risk coefficients were higher for respiratory and cardiovascular mortality, showing a delayed effect over several days.Since the 1990s, a number of studies have shown that daily pollution variations in urban ambient air are associated with an increase in mortality even when the fluctuations are below international standards [1,2]. The results of the EMECAS Project [3] (Spanish Multicenter Study on Air Pollution and Health), which was conducted on the basis of data from 13 Spanish cities with an overall population of over 10 million inhabitants, corroborated the existence of an association between air pollution and mortality among the urban Spanish population, indicating higher risk estimates for specific causes, mainly respiratory diseases. This study, however, did not include any locations in the Canary Islands.The island factor of the cities of Las Palmas de Gran Canaria (L/P de Gran Canaria) and Sant
Fascitis necrosante por Apophysomyces elegans, moho de la familia mucoraceae, en paciente inmunocompetente
Ruiz,Carmen Elena; Arango,Myrtha; Correa,Ana Lucía; López,Luz Saider; Restrepo,Angela;
Biomédica , 2004,
Abstract: a case study is presented of a 7-year-old boy, seriously injured in a car accident, who developed a fatal infection due to aphophysomyces elegans - a mold of the mucoracea family. fungal invasion was initially manifested by a spotted wound in the left lumbar region which developed into a necrotizing fasciitis. later this progressed to the right lumbar area, including the gluteus and the corresponding flank. antimycotic treatment proved ineffective, and the child died 8 weeks after the accident. other cases due to this fungus are reviewed.
Factors associated with breastfeeding in children less than one year of age in the city of Cartagena, Colombia
Díaz,Carmen Elena; López,Rossana; Herrera,Indira; Arena,Diana; Giraldo,Carolina; Gonzáles,Laura;
Colombia Médica , 2011,
Abstract: introduction:the practice of breastfeeding represents multiple benefits to children; however, several studies show that there has been a gradual loss of breastfeeding habits in industrialized and developing countries, mainly because the great diversity of types of milk. additionalliy, there was the presence of biological and socio-cultural factors, which influence and modify this practice and generate a negative impact on the health of the infant population. in colombia, in 2005, it was reported that the median duration of exclusive breastfeeding was 2.2 months and the median duration was 14.9 months total; likewise, the department of bolivar reported a median slightly over a month. objective: to determine the relationship between social and biological factors in the prevalence of exclusive breastfeeding in children under one year of age in cartagena, colombia. materials and methods: cross-sectional study, the population consisted of the mothers of 23,109 children less than one year of age, the sample was 562 mothers. the probability sampling was stratified by clusters of three locations in the city where every neighborhood was a cluster. after selecting the neighborhood, a simple random sampling was conducted by city blocks. mothers of children under one year of age were sought in their homes in the city blocks selected. the information was collected through the survey ?breastfeeding and complementary feeding? used by profamilia, demographic characteristics were demographic characteristics were also investigated. results: the median for breastfeeding was 2 months, social factors associated were: not using a feeding bottle (ci: 2.37-5.38), nuclear family membership (ci: 1.29-2.72), not being a mother head of household (ci: 0.27-0.62), and the biological factor showing association was temporary suspension of breastfeeding (ci: 0.23-0.70). conclusion: the duration of the exclusive breastfeeding practice among women turned out to be very short and the practice until th
ética en la investigación con poblaciones especiales
Viada González,Carmen Elena; Ballagas Flores,Clara; Blanco López,Yasmín;
Revista Cubana de Investigaciones Biom??dicas , 2001,
Abstract: the ethical approach of science and the humanistic basis of the scientific work lead to the need of creating a suitable ethics in the research with human beigns and, particularly, with special populations. in order to define the moral standards to be taken into account when carrying out a research on children, aged people or women who are pregnant or that are nursing, it was made an analysis of the important and updated sources of international literature. some recommendations and precautions to be followed in researches with this kind of people were included here
ética en la investigación con poblaciones especiales
Carmen Elena Viada González,Clara Ballagas Flores,Yasmín Blanco López
Revista Cubana de Investigaciones Biom??dicas , 2001,
Abstract: El enfoque ético de la ciencia y la fundamentación humanista del trabajo científico conduce a la necesidad de elaborar una ética adecuada en la investigación con seres humanos y en particular en poblaciones especiales. Con el objetivo de delimitar las normas morales a tener en cuenta en investigaciones en ni os, ancianos y mujeres embarazadas o en período de lactancia, se realizó un análisis de fuentes importantes y actualizadas de la literatura internacional. Se ofrecieron algunas recomendaciones y precauciones a seguir en investigaciones con este tipo de población The ethical approach of science and the humanistic basis of the scientific work lead to the need of creating a suitable ethics in the research with human beigns and, particularly, with special populations. In order to define the moral standards to be taken into account when carrying out a research on children, aged people or women who are pregnant or that are nursing, it was made an analysis of the important and updated sources of international literature. Some recommendations and precautions to be followed in researches with this kind of people were included here
Factors associated with breastfeeding in children less than one year of age in the city of Cartagena, Colombia
Carmen Elena Díaz,Rossana López,Indira Herrera,Diana Arena
Colombia Médica , 2011,
Abstract: The practice of breastfeeding represents multiple benefits to children; however, several studies show thatthere has been a gradual loss of breastfeeding habits in industrialized and developing countries, mainly because the greatdiversity of types of milk. Additionalliy, there was the presence of biological and socio-cultural factors, which influence andmodify this practice and generate a negative impact on the health of the infant population. In Colombia, in 2005, it was reportedthat the median duration of exclusive breastfeeding was 2.2 months and the median duration was 14.9 months total; likewise,the department of Bolivar reported a median slightly over a month.Objective: To determine the relationship between social and biological factors in the prevalence of exclusive breastfeedingin children under one year of age in Cartagena, Colombia.Materials and methods: Cross-sectional study, the population consisted of the mothers of 23,109 children less than oneyear of age, the sample was 562 mothers. The probability sampling was stratified by clusters of three locations in the city whereevery neighborhood was a cluster. After selecting the neighborhood, a simple random sampling was conducted by city blocks.Mothers of children under one year of age were sought in their homes in the city blocks selected. The information was collectedthrough the survey Breastfeeding and complementary feeding used by PROFAMILIA, demographic characteristics weredemographic characteristics were also investigated.Results: The median for breastfeeding was 2 months, social factors associated were: not using a feeding bottle (CI: 2.37-5.38), nuclear family membership (CI: 1.29-2.72), not being a mother head of household (CI: 0.27-0.62), and the biologicalfactor showing association was temporary suspension of breastfeeding (CI: 0.23-0.70).Conclusion: The duration of the exclusive breastfeeding practice among women turned out to be very short and thepractice until the sixth month of life for their children was low. It was found that children born through caesarean section hada higher prevalence of maternal of maternal breastfeeding than those born vaginally.
The Stack: A New Bacterial Structure Analyzed in the Antarctic Bacterium Pseudomonas deceptionensis M1T by Transmission Electron Microscopy and Tomography
Lidia Delgado, Ornella Carrión, Gema Martínez, Carmen López-Iglesias, Elena Mercadé
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0073297
Abstract: In recent years, improvements in transmission electron microscopy (TEM) techniques and the use of tomography have provided a more accurate view of the complexity of the ultrastructure of prokaryotic cells. Cryoimmobilization of specimens by rapid cooling followed by freeze substitution (FS) and sectioning, freeze fracture (FF) and observation of replica, or cryoelectron microscopy of vitreous sections (CEMOVIS) now allow visualization of biological samples close to their native state, enabling us to refine our knowledge of already known bacterial structures and to discover new ones. Application of these techniques to the new Antarctic cold-adapted bacterium Pseudomonas deceptionensis M1T has demonstrated the existence of a previously undescribed cytoplasmic structure that does not correspond to known bacterial inclusion bodies or membranous formations. This structure, which we term a “stack”, was mainly visualized in slow growing cultures of P. deceptionensis M1T and can be described as a set of stacked membranous discs usually arranged perpendicularly to the cell membrane, but not continuous with it, and found in variable number in different locations within the cell. Regardless of their position, stacks were mostly observed very close to DNA fibers. Stacks are not exclusive to P. deceptionensis M1T and were also visualized in slow-growing cultures of other bacteria. This new structure deserves further study using cryoelectron tomography to refine its configuration and to establish whether its function could be related to chromosome dynamics.
Concerted In Vitro Trimming of Viral HLA-B27-Restricted Ligands by Human ERAP1 and ERAP2 Aminopeptidases
Elena Lorente, Alejandro Barriga, Carolina Johnstone, Carmen Mir, Mercedes Jiménez, Daniel López
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0079596
Abstract: In the classical human leukocyte antigen (HLA) class I antigen processing and presentation pathway, the antigenic peptides are generated from viral proteins by multiple proteolytic cleavages of the proteasome (and in some cases other cytosolic proteases) and transported to the endoplasmic reticulum (ER) lumen where they are exposed to aminopeptidase activity. In human cells, two different ER-resident enzymes, ERAP1 and ERAP2, can trim the N-terminally extended residues of peptide precursors. In this study, the possible cooperative effect of generating five naturally processed HLA-B27 ligands by both proteases was analyzed. We identified differences in the products obtained with increased detection of natural HLA-B27 ligands by comparing double versus single enzyme digestions by mass spectrometry analysis. These in vitro data suggest that each enzyme can use the degradation products of the other as a substrate for new N-terminal trimming, indicating concerted aminoproteolytic activity of ERAP 1 and ERAP2.
Actividades Instrumentales de la Vida Diaria en Personas Mayores atendidas en la red de Atención Primaria de Salud en la comuna de Chillán Viejo-Chile
Lara Jaque,Roxana Alejandra; López Espinoza,Miguel ángel; Espinoza Lavoz,Elena del Carmen; Pinto Santuber,Cecilia;
Index de Enfermería , 2012, DOI: 10.4321/S1132-12962012000100006
Abstract: justification. national and international statistics show that health teams will have to respond to the needs of caring for older people, considering the implication of the functional capacity as a variable of evaluation of their health condition. objective. to determine those characteristics in older people that may influence their functional capacity, according to the instrumental activities of daily living. design. quantitative, descriptive-correlational cross sectional study. results. out of 136 individuals studied (61% female) and an average age of 73,28 ± 6,77 years old, it was observed that the instrumental activities of daily living depend significantly on: literacy level (p=0,002), instruction level (p=0,024), community participation (p=0,007), nutritional status (p=0,028) and depression (p=0,018). conclusion. social, physical and mental factors relate to the functionality of older people. it is fundamental to create public policies to protect this group in the population, with a cross functional and systemic approach.
Extramammary paget?s disease of scrotum: A case with local lymph node metastasis
Parada,David; Moreira,Otto; López,Carmen; Rodríguez,Jhonny; Marín,María Elena; Farías,Rosa M.;
Archivos Espa?oles de Urología (Ed. impresa) , 2005, DOI: 10.4321/S0004-06142005000100015
Abstract: objetive: we describe the clinical, histological and immunohistochemical studies in a case of extramammary paget′s disease localized in the scrotum with lymph node inguinal metastasis. methods/results: a 80-year old man consulted with a one-year history of a pruritic erythematous skin rash of the scrotum. physical examination showed demarcated erythematous lesion involving the scrotum and right inguinal adenopathy. final histological examination revealed extramammary paget′s disease with inguinal metastasis. conclusion: extramammary paget′s disease of the scrotum is a rare disease. this pathological condition may spread to dermal region and the regional lymph nodes. although genitourinary cancer may accompany scrotal extramammary paget′s disease, an extensive search for cancer may be unnecessary..
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