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Search Results: 1 - 10 of 10309 matches for " Carmen Dorobat "
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Laura Ghibu,Egidia Miftode,Olivia Dorneanu,Carmen Dorobat
Jurnalul de Chirurgie , 2011,
Abstract: Acinetobacter baumannii is an opportunistic pathogen of increasing relevance in hospital infections during the last 15 years.This organism causes a wide range of infection .Extensive use of antibiotics within hospitals has contribute to the emergence of multidrug-resistent A.baumannii strains that exhibit resistance to a wide range of antibiotics ,including carbapenems.We report the case of an 37 years old man diagnosed with Acinetobacter multidrug-resistant post-neurosurgical meningitis with fatal outcome.
Personalized Training in Romanian SME’s ERP Implementation Projects
Informatica Economica Journal , 2010,
Abstract: Many practitioners and IS researchers have stated that the overwhelming majority of Enter-prise Resource Planning (ERP) systems implementations exceed their training budget and their time allocations. In consequence many Romanian SMEs that implement an ERP system are looking to new approaches of knowledge transfer and performance support that are better aligned with business goals, deliver measurable results and are cost effective. Thus, we have begun to analyze the training methods used in ERP implementation in order to provide a so-lution that could help us maximize the efficiency of an ERP training program. We proposed a framework of an ERPTraining module that can be integrated with a Romanian ERP system and which provides a training management that is more personalized, effective and less ex-pensive.
Characteristics of tuberculous meningitis in HIV-infected patients
A Hristea,C Manciuc,E Zaharia-Kezdi,C Dorobat
Journal of the International AIDS Society , 2012, DOI: 10.7448/ias.15.6.18413
Abstract: Background: Tuberculous meningitis (TBM) has a substantial mortality even with anti-tuberculous treatment, in HIV-non-infected patients. Purpose of the study. The objectives were to describe clinical and laboratory differences of TBM in HIV-infected versus HIV non-infected patients and to assess risk factors of death in HIV-infected patients. Methods: We retrospectively analyzed patients admitted to four infectious diseases hospitals in Romania, between 2001 and 2011, with TBM. Patients were defined as having TBM according to a consensus definition published by Marais et al. [1] and further divided into three categories of TBM (definite, probable and possible). Results: We identified 162 patients with TBM of which 47 (29%) tested positive for HIV infection. Sixty-six patients had definite, 53 probable and 43 possible TBM. Out of the 47 HIV-infected patients 25 had definite, 17 probable and 5 possible TBM. TBM in HIV-infected patients vs. HIV non-infected patients was significantly associated in multivariable analysis with younger age (p=0.01), in-hospital mortality (p<0.001), absence of meningean syndrome (p=0.021), and absence of cranial nerve palsy (p=0.036). HIV-infected patients who died had a median CD4 count of 61 cells/mm3 (IQR 21-132) vs. 135 cells/mm3 (IQR 61–255) in patients who survived (p=0.014). HIV infection was diagnosed before TBM episode in 35 (75%) patients. Twenty-four (51%) HIV-infected patients had concomitant extra-central nervous system tuberculosis. Conclusions: HIV infection is associated with increased mortality in patients with TBM. Most of our patients with TBM were late presenters. Death in HIV infected patients was associated with a lower median CD4 count.
Application of Statistical Methods to Assess Carbon Monoxide Pollution Variations within an Urban Area  [PDF]
Carmen Capilla
International Journal of Geosciences (IJG) , 2012, DOI: 10.4236/ijg.2012.325090
Abstract: In recent years there have been considerable new legislation and efforts by vehicle manufactures aimed at reducing pollutant emission to improve air quality in urban areas. Carbon monoxide is a major pollutant in urban areas, and in this study we analyze monthly carbon monoxide (CO) data from Valencia City, a representative Mediterranean city in terms of its structure and climatology. Temporal and spatial trends in pollution were recorded from a monitoring net- work that consisted of five monitoring sites. A multiple linear model, incorporating meteorological parameters, annual cycles, and random error due to serial correlation, was used to estimate the temporal changes in pollution. An analysis performed on the meteorologically adjusted data reveals a significant decreasing trend in CO concentrations and an annual seasonal cycle. The model parameters are estimated by applying the least-squares method. The standard error of the parameters is determined while taking into account the serial correlation in the residuals. The decreasing trend im- plies to a certain extent an improvement in the air quality of the study area. The seasonal cycle shows variations that are mainly associated with traffic and meteorological patterns. Analysis of the stochastic spatial component shows that most of the intersite covariances can be analyzed using an exponential variogram model.
Brief Note on a Scalar Quantum Field with Finite Lifetime in a Lorentz Invariant Non-Rectangular Euclidean Space  [PDF]
Carmen Tornow
Journal of Modern Physics (JMP) , 2014, DOI: 10.4236/jmp.2014.514135

A not necessary rectangular Euclidean space (NoNRES) is constructed, in which one obtains a generally Lorentz invariant scalar product for the low energy sector (LES). This sector is defined for energies below the Planckian limit. If the energy is zero, the NoNRES becomes rectangular and due to the Lorentz invariance, it is applicable for the complete LES of the theory. In contrast to the usual Minkowski space the metric of the NoNRES depends on the kinetic energy of the observed quantum particles. It is assumed that this metric may be useful to derive the scattering cross-section of the corresponding quantum field theory. This assumption is related to the occurrence of divergent loop momentum integrals caused by including the infinite energy range above the Planckian limit (high energy sector or HES). Due to its energy dependence, the metric in both energy sectors differs. In the HES, it depends on the effective dimension of the NoNRES. This dependency results from fluctuations of the space-time above the Planckian limit. Even if they are not part of the theory (as they would be in quantum gravity), these fluctuations should not be ignored. The effective dimension decreases if the energy of the considered particle increases. Since this is true for the HES only, the ultraviolet divergences of loop integrals seem to vanish without distorting the results of the LES. The mechanism is illustrated by calculating the tadpole integral occurring for a simple self-interacting scalar quantum field (with the Higgs mass as example). One obtains a finite contribution for the integral and consequently for the lifetime of the scalar particle.

Human Health, Rights and Wind Turbine Deployment in Canada  [PDF]
Carmen Krogh, Brett Horner
Open Journal of Social Sciences (JSS) , 2017, DOI: 10.4236/jss.2017.55012
Abstract: Canada has ratified international conventions which recognize the individual’s right to the enjoyment of the highest attainable standard of health. Despite the adoption of these covenants governments sometimes support policies and practises which trade off individual human health with other conflicting interests. This review evaluates the individual’s right to health against government policies and practices which support wind energy deployment in Canada. Our analysis presents government documents, peer reviewed literature, and other references which support the conclusion that wind energy deployment in Canada can be expected to result in avoidable harm to human health. This harm conflicts with contemporary health and social justice principles. Governments have a responsibility to help Canadians maintain and improve their health by generating effective responses for the prevention of avoidable harm. Individuals have a right to make informed decisions about their health. Knowledge gaps and potential risks to health should be fully disclosed. Individuals should not be exposed to industrial wind turbines without their informed consent.
Wolbachia induces sexual isolation in Drosophila melanogaster and Drosophila simulans  [PDF]
Ialah Gazla, Maria Carmen Carracedo
Open Journal of Genetics (OJGen) , 2011, DOI: 10.4236/ojgen.2011.12005
Abstract: Wolbachia are a group of intracellular bacteria, ma-ternally transmitted from infected females to their offspring, which affect a wide range of arthropods. Their presence is associated with Cytoplasmic Incompatibility (CI) in crosses between infected males and uninfected females and between populations carrying different strains of Wolbachia. The negative influence of Wolbachia a infection on progeny fitness in incompatible crosses can be considered a first step in the appearance of reproductive isolation between infected and uninfected individuals. In this work, we examined the possibility of assortative mating in response to Wolbachia infection, a response that evolved as an incipient mechanism of sexual isolation in the species D. melanogaster and D. simulans. We found that the females of each species could detect the presence of the bacterium in the other sex and chose to mate with males who had the same state of infection, whereas the males randomly attempted to mate with both infected and uninfected females. Thus, Wolbachia may act as an additive factor influencing sexual isolation in Drosophila populations and may play a role in speciation events.
Nanomaterials for Drugs Delivery  [PDF]
Francisco Márquez, Carmen Morant
Soft Nanoscience Letters (SNL) , 2014, DOI: 10.4236/snl.2014.43007

As expected for years, nanotechnology has revolutionized engineering, biology, chemistry, physics and medicine of today. These disciplines are evolving thanks to the ongoing development of new materials and applications. Nanomedicine, as application of nanotechnology in the field of health care, has undergone unprecedented development. Some of these changes have real applications as, for example, the use of nanoparticles in MRI imaging, in hyperthermia, in immunotherapy, or to improve the bioavailability of drugs, among others [1]-[3].

When a drug is administered to a patient, the blood distributes it throughout the body. In the case of very localized diseases (i.e. tumors), only a small fraction of the drug reaches the target. Chemotherapy is one of the most aggressive treatment options used in some types of cancer, and is usually administered intravenously. In this type of therapy, the drug circulates throughout the body, reaching and destroying healthy and cancerous tissues, producing side effects throughout the body, sometimes with serious consequences for the health of the patient (nephrotoxicity, cardiotoxicity, peripheral neuropathy, anemia, etc.). Among the many applications of nanotechnology, the fabrication of nanostructures capable of safely transporting these drugs is seen as a strategy for reducing these side effects. Nanoparticles are able to carry and release the drug in the right place and with the required dose, greatly reducing the problems associated with direct treatment with these drugs.

In recent years, there have been continuous improvements in the design and development of new tailor-made drug delivery systems [4], including hollow magnetic nanoparticles, liposomal structures, dendrimers, nanoporous silicon, etc. These structures can be obtained with different molecular weights (in the case of polymers), structures, shapes, and even with the appropriate functional groups for interaction at the desired positions. However, a great effort is still required to solve many of the current problems [5], including toxicity, aggregation, solubility and stability in the human body, physiological processes of elimination, identification of targets by highly specific receptors, controlled drug release over time, etc.

Nanomaterials for Sensor Applications  [PDF]
Francisco Márquez, Carmen Morant
Soft Nanoscience Letters (SNL) , 2015, DOI: 10.4236/snl.2015.51001
Abstract: Recently, a large part of the advances in nanotechnology have been directed towards the development of high-speed electronics, more efficient catalysts, and sensors. This latter group of applications has great relevance and unprecedented development potential for the coming years.So far, some of the main objectives for the development of sensors have focused on making more sensitive, effective and specific sensing devices.The improvement of these systems and the increase of specificity are clearly associated with a decrease in size of the components, which can lead to obtaining more rapid action, almost in real time. Nanomaterials currently used in sensor development include a long list of nanostructured systems, as for example: metal nanotubes, nanowires, nanofibers, nanocomposites, nanorods, nanoparticles, nanostructured polymers, and different allotropes of carbon as carbon nanotubes, graphene or fullerenes, among others.
Critical Review of Literature on Radiologic Technology Education Program Evaluation  [PDF]
Carmen T. Saunders-Russell
Open Journal of Medical Imaging (OJMI) , 2016, DOI: 10.4236/ojmi.2016.64011
Abstract: Curriculum has achieved a varied record of success in influencing health based practices and developing professional skills. Designing and implementing an effective radiologic technology educational program curriculum requires a disciplined pedagogical approach where the instructor performs a thorough situational analysis, develops a theory based and pragmatic learning plan, and implements a course of study in accordance with the established educational guidelines and requirements. Diligent efforts are needed to enhance the relationship amongst curriculum developers and evaluators. The collection of information at the formative stage: followed by process evaluation to assess implementation as the curriculum progresses, and summative evaluation to assess impact is required for accreditation of program in the United States by the Joint Review Committee for Education in Radiologic Technology. Formative evaluation research is used to enhance effectiveness of the curriculum, guide development of teaching and learning strategies, and reveal promising and ineffective components of curriculum. This review of literature provides evidence as to what is considered to be the best practice in the program evaluation/accreditation process.
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