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Search Results: 1 - 10 of 73785 matches for " Carlos Eduardo Yamasaki Sato "
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Th e Dynamics of Capabilities in the Transition to Telecommunications Next Generation Networks
Carlos Eduardo Yamasaki Sato,Dario Eduardo Amaral Dergint,Kazuo Hatakeyama
Brazilian Journal of Operations & Production Management , 2010,
Abstract: This paper examines the dynamics of capabilities in the transition to the socalled Next Generation Network (NGN), in the telecommunications industry. This transition is occurring in major incumbent fixed telecommunications operators like BT (British Telecom), France Telecom and Deutsche Telekom, among others, where the innovation gap seems to be more challenging compared to mobile operators and cable TV companies. We analyze the capabilities development of BT in the United Kingdom, using documentary and interview data. The main conclusion is that, during the transition, capabilities vary rapidly in intensity: at the very beginning, strategic capabilities infl uence the decision-making and defi ne the transition, and then project capabilities are put in place to deploy the strategy, until functional capabilities take over and maintain the evolutionary path of the technology until a next major transition may occur.
Limita es das Atuais Solu es em Software: Uma Vis o para Desenvolvimento de Ferramentas em Gest o de Projetos
Dani Juliano Czelusniak,Alessandro de Oliveira Binhara,Carlos Eduardo Yamasaki Sato,Dario Eduardo do Amaral Dergint
Revista Eletr?nica de Sistemas de Informa??o , 2005,
Abstract: Diante do atual estado da evolu o tecnológica, a Gest o de Projetos torna-se cada vez mais importante dada a crescente complexidade dos projetos. Neste cenário as solu es de software existentes no mercado mostram-se ineficientes face ao dinamismo e aumento do número de variáveis que precisam ser controladas pelo gestor. Este artigo apresenta um estudo que visa verificar as atuais limita es dos softwares de auxílio ao gestor de projetos, demonstrando como novas tecnologias de desenvolvimento de software podem contribuir para a constru o de ferramentas mais eficazes. Sistemas de informa es construídos sobre os novos modelos de desenvolvimento podem ajudar no controle de projetos onde as atuais ferramentas apresentam limita es. A metodologia utilizada neste estudo foi a revis o bibliográfica para esclarecer quais s o os novos modelos de desenvolvimento, como desenvolve-se um projeto e como aplicam-se suas ferramentas de controle. Este trabalho termina apresentando sugest es em que o uso destas novas metodologias demonstra bom potencial para futuras implementa es pelo fato de serem flexíveis, por oferecer respostas em um menor prazo e por oferecer formas de tratar a n o linearidade característica dos novos projetos.
Density currents at steady regime
Barbosa, Alexandre Augusto;Mauad, Frederico Fábio;Sato, Carlos Eduardo;Silva, Ana Paula Moni;
Journal of the Brazilian Society of Mechanical Sciences and Engineering , 2010, DOI: 10.1590/S1678-58782010000300009
Abstract: this work brings as its main contribution the study of the phenomenon of density currents in non-stratified reservoirs, with flows in steady regimes. flows are analyzed for a wide range of reynolds and richardson numbers in the entrance of the reservoir. based on this hypothesis, a hybrid numeric model is presented considering the reynolds transport's equation - focusing on the conservation for volume, mass and momentum - with the intention of obtaining three-dimensional components of velocities, reduced acceleration of gravity and geometric characteristics of currents along the reservoir. it is possible to notice in the numeric simulations, mainly, the need of complementation of the model that refers to the inclusion of the entrainment coefficient and the analysis in the unsteady regime.
Discriminating Different Classes of Biological Networks by Analyzing the Graphs Spectra Distribution
Daniel Yasumasa Takahashi, Jo?o Ricardo Sato, Carlos Eduardo Ferreira, André Fujita
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0049949
Abstract: The brain's structural and functional systems, protein-protein interaction, and gene networks are examples of biological systems that share some features of complex networks, such as highly connected nodes, modularity, and small-world topology. Recent studies indicate that some pathologies present topological network alterations relative to norms seen in the general population. Therefore, methods to discriminate the processes that generate the different classes of networks (e.g., normal and disease) might be crucial for the diagnosis, prognosis, and treatment of the disease. It is known that several topological properties of a network (graph) can be described by the distribution of the spectrum of its adjacency matrix. Moreover, large networks generated by the same random process have the same spectrum distribution, allowing us to use it as a “fingerprint”. Based on this relationship, we introduce and propose the entropy of a graph spectrum to measure the “uncertainty” of a random graph and the Kullback-Leibler and Jensen-Shannon divergences between graph spectra to compare networks. We also introduce general methods for model selection and network model parameter estimation, as well as a statistical procedure to test the nullity of divergence between two classes of complex networks. Finally, we demonstrate the usefulness of the proposed methods by applying them to (1) protein-protein interaction networks of different species and (2) on networks derived from children diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) and typically developing children. We conclude that scale-free networks best describe all the protein-protein interactions. Also, we show that our proposed measures succeeded in the identification of topological changes in the network while other commonly used measures (number of edges, clustering coefficient, average path length) failed.
Discriminating different classes of biological networks by analyzing the graphs spectra distribution
Daniel Yasumasa Takahashi,Jo?o Ricardo Sato,Carlos Eduardo Ferreira,André Fujita
Computer Science , 2012,
Abstract: The brain's structural and functional systems, protein-protein interaction, and gene networks are examples of biological systems that share some features of complex networks, such as highly connected nodes, modularity, and small-world topology. Recent studies indicate that some pathologies present topological network alterations relative to norms seen in the general population. Therefore, methods to discriminate the processes that generate the different classes of networks (e.g., normal and disease) might be crucial for the diagnosis, prognosis, and treatment of the disease. It is known that several topological properties of a network (graph) can be described by the distribution of the spectrum of its adjacency matrix. Moreover, large networks generated by the same random process have the same spectrum distribution, allowing us to use it as a "fingerprint". Based on this relationship, we introduce and propose the entropy of a graph spectrum to measure the "uncertainty" of a random graph and the Kullback-Leibler and Jensen-Shannon divergences between graph spectra to compare networks. We also introduce general methods for model selection and network model parameter estimation, as well as a statistical procedure to test the nullity of divergence between two classes of complex networks. Finally, we demonstrate the usefulness of the proposed methods by applying them on (1) protein-protein interaction networks of different species and (2) on networks derived from children diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) and typically developing children. We conclude that scale-free networks best describe all the protein-protein interactions. Also, we show that our proposed measures succeeded in the identification of topological changes in the network while other commonly used measures (number of edges, clustering coefficient, average path length) failed.
Influência do veículo na eficácia da reposi??o de potássio em ratos hipocalêmicos
Petenusso, Márcio;Valenti, Vitor Engrácia;Abreu, Luiz Carlos de;Colombari, Eduardo;Fonseca, Fernando Luiz Affonso;Sato, Monica Akemi;
Revista Brasileira de Cirurgia Cardiovascular , 2009, DOI: 10.1590/S0102-76382009000400017
Abstract: introduction: patients who undergo cardiac surgery are commonly treated with diuretic therapy for the management of volume overload. the concern of hypokalemia important in the adult population submitted to cardiac surgery has been described. intravenous potassium (k+) replacement dilution is only recommended with sodium chloride 0.9% solution (sf0.9%), likely due to the putative effects of glucose solution 5% (sg5%) on insulin secretion, which influence k+ replacement quality. however, it is not yet experimentally proved the influence of sf0.9% and sg5% on k+ replacement quality. objectives: to evaluate the effects of different vehicles of k+ replacement on blood k+ levels in furosemide hypokalemic rats. methods: male wistar rats divided into four groups: k+sf, k+sg, sf and sg. jugular vein cannulation for k+ replacement and femoral vein cannulation for blood analysis. furosemide (50mg/kg) to induce hypokalemia. we prepared the following solutions: vehicle 1.6ml (sf0.9% or sg5%) + 0.4 ml de k+ (19.1%) and for control groups only vehicle 2 ml. furosemide (50 mg/kg) was used to induce hypokalaemia, it was analyzed potassium plasmatic levels 24 hours before furosemide injection, 24 hours after furosemide injection and 30 minutes after post-replacement. results: there was no significative difference in blood k+ levels before furosemide administration, after hypokalemic induction and after k+ replacement among all groups. only sf+k presented blood na+ levels increaseafter k+ replacement (p<0.05). conclusion: k+ replacement in different vehicles did not affect blood k+ levels in rats
A Case of Typical Carcinoid of the Larynx
Shintaro Sato,Yuichiro Kuratomi,Fumio Yamasaki,Akira Inokuchi
Case Reports in Otolaryngology , 2012, DOI: 10.1155/2012/717251
Abstract: We report herein a rare case of typical carcinoid occurring primarily in the epiglottis. The patient was a 70-year-old man. On initial examination, a polypoid lesion with irregular surface near the center right-hand side of the laryngeal surface of the epiglottis was observed, and a biopsy was performed. Pathological examination of the specimen suggested the possibility of adenocarcinoma. Surgical excision was performed by means of laryngomicrosurgery. A Weerda-type laryngoscope was used to open the larynx, supplemented by rigid nasal sinus surgery endoscopes, and the right-hand half of the epiglottis were excised was ensured using a CO2 laser. Postoperative pathological diagnosis was negative for adenocarcinoma and squamous cell cancer; typical carcinoid was diagnosed according to the World Health Organization criteria. Aspiration occurred postoperatively, swallowing training was therefore provided, and the patient was discharged from hospital 2 months after surgery when he was able to eat normally. As of 4 years after surgery, the patient remains under follow-up observation by means of PET-CT and neck, thoracic, and abdominal CT administered at appropriate intervals, but no findings indicating obvious recurrence or metastasis have been observed, and the patient displays good swallowing function.
Donepezil, Anti-Alzheimer's Disease Drug, Prevents Cardiac Rupture during Acute Phase of Myocardial Infarction in Mice
Mikihiko Arikawa,Yoshihiko Kakinuma,Takemi Handa,Fumiyasu Yamasaki,Takayuki Sato
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0020629
Abstract: We have previously demonstrated that the chronic intervention in the cholinergic system by donepezil, an acetylcholinesterase inhibitor, plays a beneficial role in suppressing long-term cardiac remodeling after myocardial infarction (MI). In comparison with such a chronic effect, however, the acute effect of donepezil during an acute phase of MI remains unclear. Noticing recent findings of a cholinergic mechanism for anti-inflammatory actions, we tested the hypothesis that donepezil attenuates an acute inflammatory tissue injury following MI.
Timing of Shell Size Increase and Decrease of the Planktic Foraminifer Neogloboquadrina pachyderma (Sinistral) During the Pleistocene, IODP Exp. 303 Site U1304, the North Atlantic Ocean
M. Yamasaki, M. Matsui, C. Shimada, S. Chiyonobu and T. Sato
The Open Paleontology Journal , 2008, DOI: 10.2174/1874425700801010018]
Abstract: We made shell size measurements of the planktic foraminifer Neogloboquadrina pachyderma (sinistral) using samples from IODP Site U1304, the North Atlantic. We found that mean and maximum shell sizes began to increase around 1.1 Ma, and that several episodic changes in test size occurred during 0.6 0.35 Ma. Test size reached a maximum during the late Quaternary. Based on correlation with previous investigations, we have confirmed that these changes in foraminiferal shell size occurred on an inter-ocean scale.
A Case of Typical Carcinoid of the Larynx
Shintaro Sato,Yuichiro Kuratomi,Fumio Yamasaki,Akira Inokuchi
Case Reports in Otolaryngology , 2012, DOI: 10.1155/2012/717251
Abstract: We report herein a rare case of typical carcinoid occurring primarily in the epiglottis. The patient was a 70-year-old man. On initial examination, a polypoid lesion with irregular surface near the center right-hand side of the laryngeal surface of the epiglottis was observed, and a biopsy was performed. Pathological examination of the specimen suggested the possibility of adenocarcinoma. Surgical excision was performed by means of laryngomicrosurgery. A Weerda-type laryngoscope was used to open the larynx, supplemented by rigid nasal sinus surgery endoscopes, and the right-hand half of the epiglottis were excised was ensured using a CO2 laser. Postoperative pathological diagnosis was negative for adenocarcinoma and squamous cell cancer; typical carcinoid was diagnosed according to the World Health Organization criteria. Aspiration occurred postoperatively, swallowing training was therefore provided, and the patient was discharged from hospital 2 months after surgery when he was able to eat normally. As of 4 years after surgery, the patient remains under follow-up observation by means of PET-CT and neck, thoracic, and abdominal CT administered at appropriate intervals, but no findings indicating obvious recurrence or metastasis have been observed, and the patient displays good swallowing function. 1. Introduction Neuroendocrine tumors of the larynx are rare. In 2003, however, the World Health Organization (WHO) issued a classification of laryngeal neuroendocrine tumors in line with that of lung tumors [1]. According to this new definition, typical carcinoid is regarded as a well-differentiated neuroendocrine carcinoma and is a rare tumor of the larynx [1–6]. We treated a patient with this rare typical carcinoid of the larynx by means of laryngomicrosurgery supplemented with rigid sinus surgery endoscopes and used a CO2 laser for en bloc resection and removal. 2. Case Study Patient A 70-year-old man. Main Complaint Tumorous mass of the epiglottis. Disease History When the patient underwent upper intestinal endoscopy at a local hospital in February 2008, a tumorous lesion was identified in the larynx. He was referred to his nearest ear, nose, and throat clinic, which found a tumor of the epiglottis and referred him to our department. Previous Medical History Coronary artery stent inserted after myocardial infarction at 65 years old. Smoking History Ten cigarettes/day from 20 to 65 years old; quit smoking thereafter. Drinking History Beer 350?mL/day (three go (a unit corresponding to 180?mL) of shochu/day up to 65 years old) were reported. Local Findings A
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