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Search Results: 1 - 10 of 5379 matches for " Carla Tonini "
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The Jews in Poland after the Second World War. Most Recent Contributions of Polish Historiography
Carla Tonini
Quest : Issues in Contemporary Jewish History. , 2010,
Abstract: In recent years Polish historians have shown a growing interest in the history of the Jews in Poland after 1945. Studies on this topic had started – although in a sporadic way - in the 1960s, intensified in the 1980s and at the turn of the twenty first Century they have focused on three main issues: post-war anti-Semitism; emigration and the creation of the State of Israel, and the restitution of property. The aim of this article is to set these studies in the Polish political and cultural context in which they were written in order to highlight elements of change and continuity within the historical debate.
The Teaching of Sign Language in Undergraduate Nursing Courses: A Descriptive Study as an Attribute to the Integrality of Care  [PDF]
Wiliam César Alves Machado, Carla Oliveira Shubert, Athaynne Ramos de Aguiar Prado, Edicléa Mascarenhas Fernandes, Teresa Tonini, Míriam Garcia Leoni
Health (Health) , 2015, DOI: 10.4236/health.2015.714200
Abstract: Background: Current and future generations of nurses must be prepared to communicate and properly care for deaf patients. The objective of this study is to describe how Brazilian Sign Language is taught in undergraduate Nursing courses. Method: This was a descriptive study with a qualitative approach, performed with fifteen professors from four universities, two public and two private and in the metropolitan region of Rio de Janeiro, through individual interviews with an analysis procedure guided by Content Analysis. Results: The teaching is restricted to the adoption of planned and established approaches to sign language and procedures to assess theoretical contents and practical domains sign language teaching exclusively in elective course often offered through the online platform. Conclusion: We conclude that professors are not prepared for the teaching of sign language and that curricula need to be appropriate to the demand of full and indistinct assistance to the population’s needs.
Transcribed-ultra conserved region expression profiling from low-input total RNA
Paola Scaruffi, Sara Stigliani, Simona Coco, Franscesca Valdora, Carla De Vecchi, Stefano Bonassi, Gian Tonini
BMC Genomics , 2010, DOI: 10.1186/1471-2164-11-149
Abstract: We present a novel application of Ribo-SPIA? isothermal linear amplification of minute RNA quantities for quantifying Transcribed-UCR (T-UCR) expression by quantitative PCR. Direct comparison of non-amplified with amplified cDNA in two neuroblastoma cell lines showed that the amplification approach increases sensitivity and repeatability in T-UCR quantification. It is noteworthy that the Ribo-SPIA? step allowed us to analyze all 481 T-UCRs by using 150 ng of RNA, while introducing a minimal bias and preserving the magnitude of relative expression. Only the less abundant T-UCRs have high intra-assay variability, consistently with the Poisson distribution statistics and stochastic effects on PCR repeatability.We demonstrated that the quantification procedure shown here is an accurate and reliable technique for genome-wide non coding gene (i.e., UCRs) profiling using small amounts of RNA. This issue is particularly important because studies of transcription regulation are increasingly conducted in small homogeneous samples, such as laser capture microdissected or sorted cell populations.Ultra Conserved Regions (UCRs) are a class of noncoding sequences discovered in 2004 by Bejerano and colleagues [1,2]. The UCRs are located in both intra- and inter-genic regions and 53% of them are nonexonic, whereas the remaining 47% are either overlapping mRNAs or possibly exonic. Since UCRs represent a group of 481 sequences (200-779 bp in length) that are 100% conserved among orthologous regions of human, mouse, and rat genomes, it has been suggested they may be involved in ontogeny and phylogeny of mammals and other vertebrates [3]. Previous studies identified a functional role for these noncoding sequences both in regulation of alternative splicing and in promoting the expression of several genes [3]. Calin et al. [4] demonstrated that UCRs are significantly altered at both genomic and expression levels in adult chronic lymphocytic leukemias, colorectal and hepatocellular carcino
Transcribed-ultra conserved region expression is associated with outcome in high-risk neuroblastoma
Paola Scaruffi, Sara Stigliani, Stefano Moretti, Simona Coco, Carla De Vecchi, Francesca Valdora, Alberto Garaventa, Stefano Bonassi, Gian Tonini
BMC Cancer , 2009, DOI: 10.1186/1471-2407-9-441
Abstract: We analyzed expression of 481 Ultra Conserved Regions (UCRs) by reverse transcription-quantitative real-time PCR and of 723 microRNAs by microarrays in 34 high-risk, stage 4 neuroblastoma patients.First, the comparison of 8 short- versus 12 long-term survivors showed that 54 UCRs were significantly (P < 0.0491) over-expressed in the former group. For 48 Ultra Conserved Region (UCRs) the expression levels above the cut-off values defined by ROC curves were strongly associated with good-outcome (OS: 0.0001

Políticas públicas e turismo: enoturismo no Vale dos Vinhedos/RS
Tonini, Hernanda
PASOS : Revista de Turismo y Patrimonio Cultural , 2008,
Abstract: The various types of tourism aim to consolidate the activity as a product, marketing leisure, culture, past and present targeted to what drives the tourist. Given that, this study aimed to analyze the role played by the government and by public policies designed to chart a course for a touristic tipology in growth: the wine tourism, trips motivated from the interest in the wine and the producer region. The qualitative field method was implemented through descriptive-exploratory research characterized by a case study in the Vale dos Vinhedos. A collection of basic data was compiled from interviews with local private sector representatives and Secretaries of Tourism in the Bento Gon alves, Monte Belo do Sul and Garibaldi municipalities, all located in this region. Among the findings, the Government participate in important points to build the route, however the lack of a policy specifically targeted to the wine tourism tends to compromise its development in the Vale dos Vinhedos.
Phenology of brazil nut (Bertholletia excelsa Humb.& Bonpl., Lecythidaceae) in south of Roraima state
Helio Tonini
CERNE , 2011,
Abstract: This work was carried out in order to study the phenological pattern of brasil-nut trees in natural forest located in the south of Roraima state, in order to relate the frequency of occurrence of phenophases with rainfall. For the phenological survey 20 adult trees (DBH > 50 cm) were selected in a permanent sample plot of 9 ha. The phenological observations occurred fortnightly from February 2006 to February 2009, when data were collected on the presence or absence of events of flowering, fruiting, leaf flushing and leaf fall for each tree. The Index of population synchrony was used for estimating the synchrony of phenological events. The flowering of brasil-nut proved to be regular, annual, long and synchronous and was correlated with the reduction of rainfall. The fruiting was regular and synchronous, and dispersal was correlated with rainfall reduction. The phenological pattern of leaf flushing tended to vary yearly, being around the continual one in 2007 and bimodal in 2006 and 2008. It was noticed a higher proportion of trees falling leaves between August and October which characterizes a period of transition between the dry and the rainy time with sensitive reduction of rainfall.
The role of galaxy formation in the structure and dynamics of dark matter halos
Chiara Tonini
Physics , 2009,
Abstract: The structure and dynamics of dark matter halos, as predicted by the hierarchical clustering scenario, are at odds with the properties inferred from the observations at galactic scales. My Thesis addresses this problem by taking an evolutionary approach. I analysed in detail the many and different observational evidences of a discrepancy the predicted halo equilibrium state and the one inferred from the measurable properties of disk galaxies, as well as of the scaling relations existing between the angular momentum, geometry and mass distribution of the luminous and dark components, and realized that they all seem to point towards the same conclusion: the baryons hosted inside the halo, by collapsing and assembling to form the galaxy, perturb the halo equilibrium structure and made it evolve into new configurations. From the theoretical point of view, the behaviour of dark matter halos as collisionless systems of particles makes their equilibrium structure and mass distribution extremely sensitive to perturbations of their inner dynamics. The galaxy formation occurring inside the halos is a tremendous event, and the dynamical coupling between the baryons and the dark matter during the protogalaxy collapse represents a perturbation of the halo dynamical structure large enough to trigger a halo evolution, according to the relative mass and angular momentum of the two components. My conclusion is that the structure and dynamics of dark matter halos, as well as the origin of the connection between the halo and galaxy properties, are to be understood in in terms of a joint evolution of the baryonic and dark components, originating at the epoch of the collapse and formation of the galaxy.
The metallicity bimodality of globular cluster systems: a test of galaxy assembly and of the evolution of the galaxy mass-metallicity relation
Chiara Tonini
Physics , 2012, DOI: 10.1088/0004-637X/762/1/39
Abstract: (Abridged) We build a theoretical model to study the origin of the globular cluster metallicity bimodality in the hierarchical galaxy assembly scenario, based on the observed galaxy mass-[O/H] relation and the galaxy stellar mass function up to z ~4, and on theoretical merger rates. We derive a new galaxy [Fe/H]-M(star) relation as a function of z, and by assuming that GCs share the metallicity of their parent galaxy when they form, we populate the merger tree with GCs. We perform a series of Monte-Carlo simulations of the galaxy assembly, and study the properties of the final GC population as a function of galaxy mass, assembly and star formation history, and under different assumptions for the evolution of the galaxy mass-[Fe/H] relation. The main results are: 1) The hierarchical clustering scenario naturally predicts a metallicity bimodality in the galaxy GC population: the metal-rich GCs are formed in the galaxy main progenitor around z~2, and the metal-poor GCs are accreted from satellites and formed at z~3-4. 2) The model reproduces the observed relations for the metallicity of the metal-rich and metal-poor GCs as a function of galaxy mass. The positions of the metal-poor and metal-rich peaks depend exclusively on the evolution of the galaxy mass-[Fe/H] relation and the [O/Fe], both of which can be constrained by this method. We find that the galaxy [O/Fe] evolves linearly with z from a value of ~0.5 at z~4 to a value of ~0.1 at z=0. 3) Given a galaxy mass, the relative strength of the metal-rich and metal-poor peaks depends exclusively on the galaxy assembly and star formation history: galaxies in denser environments and/or early types galaxies show a larger fraction of metal-poor GCs, while galaxies with a sparse merger history and/or late type galaxies are dominated by metal-rich GCs. 4) The GC metallicity bimodality disappears for galaxy masses below M(star)~1e9, and for z>2.
Sheafification functors and Tannaka's reconstruction
Fabio Tonini
Mathematics , 2014,
Abstract: We introduce "sheafification" functors from categories of (lax monoidal) linear functors to cat- egories of quasi-coherent sheaves (of algebras) of stacks. They generalize the homogeneous sheafification of graded modules for projective schemes and have applications in the theory of non-abelian Galois covers and of Cox rings and homogeneous sheafification functors. Moreover, using this theory, we prove a non-neutral form of Tannaka's reconstruction, extending the classical correspondence between torsors and strong monoidal functors.
Stacks of ramified Galois covers
Fabio Tonini
Mathematics , 2013,
Abstract: Given a finite, flat and finitely presented group scheme $G$ over some base $S$, we introduce the notion of ramified $G$-covers and study the moduli stack $G$-Cov they form. The thesis is divided in three parts. The first one concerns the case when $G$ is a diagonalizable group scheme and it essentially coincides with arxiv:1106.2347. In the second part I deal with the general case. Assuming that the base S is affine and given an $S$-scheme $T$, I interpret $G$-covers of $T$ as particolar (lax) monoidal functors from the category of finite, $G$-equivariant locally free sheaves over $S$ to the category of finite locally free sheaves over $T$, extending the classical Tannakian correspondence between $G$-torsors and strong monoidal functors as above. Using this point of view, I prove that $G$-Cov is always reducible if $G$ is a non-abelian linearly reductive group. When $G$ is constant and tame I also give a criterion to detect when a $G$-cover of a regular in codimension one, integral scheme has regular in codimension one total space in terms of the functor associated with the cover. In the last part I focus on the case $G=S_3$, prove that $S_3$-Cov has exactly two irreducible components and describe the principal one. I also describe particular open loci of $S_3$-Cov, that is particular families of $S_3$-covers, classify $S_3$-covers of regular schemes whose total space is regular and compute the invariants of $S_3$-covers of smooth surfaces.
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