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Search Results: 1 - 10 of 11372 matches for " Cao Lichao "
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Books Recommended Model Based on Association Rules Comprehensive Evaluation

Lu Yonghe,Cao Lichao,

现代图书情报技术 , 2011,
Abstract: With the research of association rules comprehensive evaluation, this article proposes a books recommended model based on the factors of Support, Confidence, Jaccard Interestingness, Attraction and Profit, and it is also oriented to online bookstores and digital libraries. At the same time, this article determines the weights of the factors in the model by the entropy method and the relative comparison method, and research on the algorithm of the model. Finally, it verifies the function of the model by the developed online bookstore system. The running results of the online bookstore system show that the model can provide the recommended book for users excellently.
Dialdehyde starch nanoparticles as antitumor drug delivery system: An in vitro, in vivo, and immunohistological evaluation
SuYao Xiao,XuanMing Liu,ChunYi Tong,LiChao Zhao,XiaoJuan Liu,AiMei Zhou,Yong Cao
Chinese Science Bulletin , 2012, DOI: 10.1007/s11434-012-5342-5
Abstract: Sustaining the release of therapeutic nanoparticles in a cell-, tissue-, or disease-specific manner is a potentially powerful technology. A new drug carrier-dialdehyde starch nanoparticle (DASNP) that can sustain the loading and release of 5-fluorouracil (5-Fu) antitumor drug is reported in this study. IR spectrophotometer and 1H NMR confirmed the formation of aldehyde groups, and scan electron microscope determinations showed that the dialdehyde starch nanoparticles obtained had an average diameter of 90 nm. 5-Fu, the model drug, was conjugated into nanoparticles by aldehyde groups. These 5-Fu-binding nanoparticles significantly enhanced breast cancer cell (MCF-7) inhibition in vitro compared with free 5-Fu. After subcutaneous 0 injection in the breast tumor-loaded rats, 5-Fu-DASNP exhibited remarkable tumor-inhibitory efficacy determined by measuring tumor weight in vivo. The tumor inhibition of 5-Fu-DASNP was 61%±6%, whereas that of free 5-Fu was only 42%±4%. Bcl-2/Bax immunohistochemistry studies indicated that 5-Fu-DASNP remarkably induced tumor tissue necrosis. These results demonstrated that the DASNP prepared in this work is a potentially effective drug carrier.
On the Variability of Interlanguage
Lichao Song
Theory and Practice in Language Studies , 2012, DOI: 10.4304/tpls.2.4.778-783
Abstract: The study of second language acquisition involves many aspects, among which interlanguage is an important one. Research on interlanguage and its various characteristics may make a great difference in the study of second language acquisition. This paper tends to explore one of the characteristics of interlanguage, its variability, so as to study its role in second language acquisition.
The Role of Context in Discourse Analysis
Lichao Song
Journal of Language Teaching and Research , 2010, DOI: 10.4304/jltr.1.6.876-879
Abstract: Discourse analysis involves many aspects, such as adjacency pairs, coherence, cohesion, and so on, among which context plays an important role. This paper intends to explore the role of context in discourse analysis on the basis of introducing different definitions and classifications of context.
Identification of Novel Biomarkers for Sepsis Prognosis via Urinary Proteomic Analysis Using iTRAQ Labeling and 2D-LC-MS/MS
Longxiang Su, Lichao Cao, Ruo Zhou, Zhaoxu Jiang, Kun Xiao, Weijing Kong, Huijuan Wang, Jie Deng, Bo Wen, Fengji Tan, Yong Zhang, Lixin Xie
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0054237
Abstract: Objectives Sepsis is the major cause of death for critically ill patients. Recent progress in proteomics permits a thorough characterization of the mechanisms associated with critical illness. The purpose of this study was to screen potential biomarkers for early prognostic assessment of patients with sepsis. Methods For the discovery stage, 30 sepsis patients with different prognoses were selected. Urinary proteins were identified using isobaric tags for relative and absolute quantitation (iTRAQ) coupled with LC-MS/MS. Mass spec instrument analysis were performed with Mascot software and the International Protein Index (IPI); bioinformatic analyses were used by the algorithm of set and the Gene Ontology (GO) Database. For the verification stage, the study involved another 54 sepsis-hospitalized patients, with equal numbers of patients in survivor and non-survivor groups based on 28-day survival. Differentially expressed proteins were verified by Western Blot. Results A total of 232 unique proteins were identified. Proteins that were differentially expressed were further analyzed based on the pathophysiology of sepsis and biomathematics. For sepsis prognosis, five proteins were significantly up-regulated: selenium binding protein-1, heparan sulfate proteoglycan-2, alpha-1-B glycoprotein, haptoglobin, and lipocalin; two proteins were significantly down-regulated: lysosome-associated membrane proteins-1 and dipeptidyl peptidase-4. Based on gene ontology clustering, these proteins were associated with the biological processes of lipid homeostasis, cartilage development, iron ion transport, and certain metabolic processes. Urinary LAMP-1 was down-regulated, consistent with the Western Blot validation. Conclusion This study provides the proteomic analysis of urine to identify prognostic biomarkers of sepsis. The seven identified proteins provide insight into the mechanism of sepsis. Low urinary LAMP-1 levels may be useful for early prognostic assessment of sepsis. Trial Registration ClinicalTrial.gov NCT01493492
A Flexible Process Monitoring and Control System Based on Data Engine and Layout Engine
Zuye Zhao,Lichao Zhang,Yusheng Shi
Lecture Notes in Engineering and Computer Science , 2012,
Discretization model of instantaneous availability for continuous-time systems
Yi Yang,Lichao Wang,Rui Kang
Journal of Computers , 2012, DOI: 10.4304/jcp.7.4.977-981
Abstract: In this paper, the instantaneous availability models in continuous and discrete time are proposed for the one-unit repairable systems with delay under exponential distributions. Prior to this, error analyses of sampling discrete distributions are given. Then, the numerical solutions for the continuous- time model and the discrete-time model are presented. The comparison of the solutions reveals that with the step length and sampling interval decreasing, the accuracy of the numerical model is much better. Also, in the same accuracy level, less computation time is needed to solve the discrete-time model. Hence, the discrete-time model is more feasible to analyze instantaneous availability. Finally an example is given to describe the application of the results.
à la recherche du figement perdu : le figement cognitif
Fasciolo Marco,Meneses Lerin Luis,Zhu Lichao
SHS Web of Conferences , 2012, DOI: 10.1051/shsconf/20120100326
Abstract: Dans cet article, nous abordons le phénomène du figement sous un angle cognitif. En décrivant des expressions figées "Adj comme SN", nous découvrons le lien implicatif entre l'expression figée et ce que nous appelons l' idée figée , en nous appuyant sur le processus d'analyse sur ces parangons de nature analogique et inférentielle. Nous remarquons de prime abord l'absence d'une définition fine du figement cognitif qui devrait englober toutes les notions stéréotypiques et doxales; nous montrons également qu'il y a réellement un hiatus entre les deux volets du figement, linguistique et cognitif ; la preuve en est que les stéréotypes et les préjugés n'ont pas besoin de la langue pour être véhiculés chez les locuteurs. Nous constatons aussi que dans "Adj comme SN", la fonction linguistique d'intensification est imposée par la langue et que le syntagme nominal pourrait correspondre à l’idée figée, il n'est alors plus question de langue. Nous proposons en revanche une catégorisation et un classement de la séquence "Adj comme SN". Pour faire émerger les deux volets du figement, nous recourons au défigement. En défigeant ce qui est figé auparavant, le locuteur présuppose le figement. Et le processus du défigement nous permet de distinguer ses deux fonctions et de révéler les effets stylistiques et les intentions du locuteur pour aboutir à une valeur heuristique de notre problématique.
Self-similar planar graphs as models for complex networks
Lichao Chen,Francesc Comellas,Zhongzhi Zhang
Physics , 2008,
Abstract: In this paper we introduce a family of planar, modular and self-similar graphs which have small-world and scale-free properties. The main parameters of this family are comparable to those of networks associated to complex systems, and therefore the graphs are of interest as mathematical models for these systems. As the clustering coefficient of the graphs is zero, this family is an explicit construction that does not match the usual characterization of hierarchical modular networks, namely that vertices have clustering values inversely proportional to their degrees.
Evolving small-world scale-free networks consist of cliques
Zhongzhi Zhang,Shuigeng Zhou,Lichao Chen
Physics , 2007, DOI: 10.1140/epjb/e2007-00229-9
Abstract: We present a family of scale-free network model consisting of cliques, which is established by a simple recursive algorithm. We investigate the networks both analytically and numerically. The obtained analytical solutions show that the networks follow a power-law degree distribution, with degree exponent continuously tuned between 2 and 3. The exact expression of clustering coefficient is also provided for the networks. Furthermore, the investigation of the average path length reveals that the networks possess small-world feature. Interestingly, we find that a special case of our model can be mapped into the Yule process.
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