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Search Results: 1 - 10 of 327931 matches for " Calil-Elias S. "
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Effect of perimuscular injection of Bothrops jararacussu venom on plasma creatine kinase levels in mice: influence of dose and volume
Calil-Elias, S.;Thattassery, E.;Martinez, A.M.B.;Melo, P.A.;
Brazilian Journal of Medical and Biological Research , 2002, DOI: 10.1590/S0100-879X2002001000018
Abstract: the effect of dose and volume of a perimuscular injection of bothrops jararacussu venom on myonecrosis of skeletal muscle was studied in mice. an increase of the venom dose (0.25 to 2.0 μg/g) at a given volume (50 μl) resulted in an increase in plasma creatine kinase (ck) levels 2 h after injection. plasma ck activity increased from the basal level of 129.27 ± 11.83 (n = 20) to 2392.80 ± 709.43 iu/l (n = 4) for the 1.0 μg/g dose. histological analysis of extensor digitorum longus muscle 4 h after injection showed lesion of peripheral muscle fibers, disorganization of the bundles or the complete degeneration of muscle fibers. these lesions were more extensive when higher doses were injected. furthermore, an increase in volume (12.5 to 100 μl) by dilution of a given dose (0.5 μg/g) also increased plasma ck levels from 482.31 ± 122.79 to 919.07 ± 133.33 iu/l (n = 4), respectively. these results indicate that care should be taken to standardize volumes and sites of venom injections.
Effect of perimuscular injection of Bothrops jararacussu venom on plasma creatine kinase levels in mice: influence of dose and volume
Calil-Elias S.,Thattassery E.,Martinez A.M.B.,Melo P.A.
Brazilian Journal of Medical and Biological Research , 2002,
Abstract: The effect of dose and volume of a perimuscular injection of Bothrops jararacussu venom on myonecrosis of skeletal muscle was studied in mice. An increase of the venom dose (0.25 to 2.0 μg/g) at a given volume (50 μl) resulted in an increase in plasma creatine kinase (CK) levels 2 h after injection. Plasma CK activity increased from the basal level of 129.27 ± 11.83 (N = 20) to 2392.80 ± 709.43 IU/l (N = 4) for the 1.0 μg/g dose. Histological analysis of extensor digitorum longus muscle 4 h after injection showed lesion of peripheral muscle fibers, disorganization of the bundles or the complete degeneration of muscle fibers. These lesions were more extensive when higher doses were injected. Furthermore, an increase in volume (12.5 to 100 μl) by dilution of a given dose (0.5 μg/g) also increased plasma CK levels from 482.31 ± 122.79 to 919.07 ± 133.33 IU/l (N = 4), respectively. These results indicate that care should be taken to standardize volumes and sites of venom injections.
Pulsed ultrasound therapy accelerates the recovery of skeletal muscle damage induced by Bothrops jararacussu venom
Saturnino-Oliveira, J.;Tomaz, M.A.;Fonseca, T.F.;Gaban, G.A.;Monteiro-Machado, M.;Strauch, M.A.;Cons, B.L.;Calil-Elias, S.;Martinez, A.M.B.;Melo, P.A.;
Brazilian Journal of Medical and Biological Research , 2012, DOI: 10.1590/S0100-879X2012007500033
Abstract: we studied the effect of pulsed ultrasound therapy (ust) and antibothropic polyvalent antivenom (pav) on the regeneration of mouse extensor digitorum longus muscle following damage by bothrops jararacussu venom. animals (swiss male and female mice weighing 25.0 ± 5.0 g; 5 animals per group) received a perimuscular injection of venom (1 mg/kg) and treatment with ust was started 1 h later (1 min/day, 3 mhz, 0.3 w/cm2, pulsed mode). three and 28 days after injection, muscles were dissected and processed for light microscopy. the venom caused complete degeneration of muscle fibers. ust alone and combined with pav (1.0 ml/kg) partially protected these fibers, whereas muscles receiving no treatment showed disorganized fascicules and fibers with reduced diameter. treatment with ust and pav decreased the effects of the venom on creatine kinase content and motor activity (approximately 75 and 48%, respectively). sonication of the venom solution immediately before application decreased the in vivo and ex vivo myotoxic activities (approximately 60 and 50%, respectively). the present data show that ust counteracts some effects of b. jararacussu venom, causing structural and functional improvement of the regenerated muscle after venom injury.
Depress?o: o mesmo acometimento para homens e mulheres?
Justo, Luís Pereira;Calil, Helena Maria;
Revista de Psiquiatria Clínica , 2006, DOI: 10.1590/S0101-60832006000200007
Abstract: the authors perform a narrative review of literature. they describe epidemiological, biological, social, and psychological aspects linked to gender differences in depressions. there are several differences between sexes regarding depressive manifestations such as the prevalence proportion of two women to one man, thoroughly described in the literature and result of well conducted trials. however, a number of uncertainties remain in basic aspects of this subject.
Mapping injuries in traffic accident victims: a literature review
Calil, Ana Maria;Sallum, Elias Aissar;Domingues, Cristiane de Alencar;Nogueira, Lilia de Souza;
Revista Latino-Americana de Enfermagem , 2009, DOI: 10.1590/S0104-11692009000100019
Abstract: the objective of this study was to identify the body regions most affected in traffic accident victims and to map the trauma and severity of the lesions. a systematic literature review using key words related to traffic accidents, transportation accidents, wounds and injuries found a total of 248 articles. the electronic bases lilacs, medline, and paho were surveyed between the years 1990 and december 2006. this review emphasized a series of conclusive studies about the most frequent body regions involved and the major injuries occurring in these situations. it also indicated information gaps in the brazilian literature. we believe that these findings are valuable for pre-hospital and intra-hospital teams and point the way to new investigations.
Biodegradabilidade e propriedades mecanicas de novas misturas poliméricas
Rosa, Derval S.;Franco, Bruno L. M.;Calil, Maria Regina;
Polímeros , 2001, DOI: 10.1590/S0104-14282001000200010
Abstract: plastics are finding increasing application in our daily life, in products such as bottles and automobiles, for packing, etc. several possibilities have been considered to minimize the environmental impact caused by the use of conventional polymers. an important alternative is the biodegradable polymer, which can be degraded through the action of naturally occurring microorganisms, such as bacteria, fungi or algae. technological applications of biodegradable polymers usually require improvements on their mechanical properties. in this context, novel polymer blends have been obtained for inexpensive applications. in the present work, the methodology of preparation of new polymer blends is described. the blends contain different quantities of starch, with poly (e-caprolactone)-(pcl), poly (?-hydroxybutyrate)-(phb) and poly (?-hydroxybutyrate-co-b-hydroxyvalerate)-(phbv). the resistance to the tensile strength of the blends with 50% in mass of starch was 35% and 60% lower than for the pure pcl and phbv, respectively. upon exposure to microorganisms in activated mud, the mixtures of pcl or phbv with larger amounts of starch display higher rates of degradation.
Vibra??o transversal: um método eficiente para classifica??o de pe?as estruturais de madeira
Calil Júnior, Carlito;Miná, Alexandre J. S.;
Revista Brasileira de Engenharia Agrícola e Ambiental , 2003, DOI: 10.1590/S1415-43662003000200025
Abstract: the classification of structural components of timber is a worldwide tendency but is still deficient in brazil. the application of nondestructive methods for classification and consequently, optimization of the use of timber in structures improves the position of the timber in comparison to more uniform structural materials. this work shows the existence of high linear correlation between the static elasticity modulus and the dynamic elasticity modulus, obtained from flexion static test and from transverse vibration test, in 326 structural pieces of southern pine specie, and indicates the efficiency of the transverse vibration test for elasticity modulus determination and for classification of structural pieces of timber.
Estudo dos programas de residência médica em Psiquiatria do Estado de S?o Paulo no ano de 1993
Calil, Luís Carlos;Contel, José Onildo Betiol;
Revista Brasileira de Psiquiatria , 1999, DOI: 10.1590/S1516-44461999000300004
Abstract: background: to study existing psychiatric medicine residency programs in s?o paulo to ensure if they are in compliance with the requirements established by various governing bodies. methods: all psychiatric medicine residency programs were studied in 1993 (n=7). the study was conducted with local visits, semi-structured interviews, and questionnaires completed by a sample of residents (n=12) and preceptors (n=7) in order to verify the existence of formal training in ambulatory, in-patient procedure, emergency medicine and rotation in neurology and mental health programs, along with a course in psychopharmacology. results: it was verified that all residency programs accomplished formal training in ambulatory, 71,4% offered training in inpatient procedure, 57% in day-care hospital, 85,7% in emergency medicine. neurology rotations were observed in 43% of the programs. none had a mental health program or formal and systematized resident performance evaluation. all prp had non-obligatory training modalities. conclusions: none of the psychiatric medicine residency programs studied fulfilled all the obligatory training modalities of normative boards. representatives of governing bodies, specialist societies and preceptors should define abilities for psychiatric formation, as to obtain standard performance in training in which the learning process might be evaluated objectively.
Síndrome de De Clèrambault: uma revis?o bibliográfica
Calil, Luís Carlos;Terra, Jo?o Ricardo;
Revista Brasileira de Psiquiatria , 2005, DOI: 10.1590/S1516-44462005000200016
Abstract: de clèrambault's syndrome (or erotomania) consists in a delusional conviction, by the patient, in which someone of higher social status has fallen in love with him or her. sexual privation can be an important psychodinamic factor on the development of this condition, but organic factors related to its genesis continue on investigation. this study revises the most important aspects that the literature brings us about this disease and its causes. the databases medline and lilacs have been consulted, and the most appropriate articles were examined. it is established that erotomania is not much found in the scientific literature, and, probably, it isn't as rare as it has been proposed. the major part of its etiologic explanation is based on psychodinamic factors, without, however, confirmed relation of cause with its clinic presentation. the progress in the neurobiologic researches will improve, perhaps, the accuracy of diagnose and treatment of these patients.
Síndrome de De Clèrambault: segundo relato de caso em português
Calil, Luís Carlos;Terra, Jo?o Ricardo;
Revista de Psiquiatria do Rio Grande do Sul , 2005, DOI: 10.1590/S0101-81082005000100010
Abstract: de clèrambault's syndrome or erotomania is a condition in which a patient develops a delusional belief of being loved by someone belonging to a higher social status. the syndrome is classified as a delusional disorder. the present study describes the case of a 46-year old woman whose symptoms have persisted for 32 years. the focus of her delusional system is a medical practitioner.
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