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Search Results: 1 - 10 of 318807 matches for " Caio F. P. Medeiros "
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Daily anticipatory rhythms of behavior and body temperature in response to glucose availability in rats
Breno T.S. Carneiro,Diego A. C. Fernandes,Caio F. P. Medeiros,Nathália L. Diniz
Psychology & Neuroscience , 2012,
Abstract: When food is available recurrently at a particular time of day, several species increase their locomotion in the hours that precede food delivery, a phenomenon called food anticipatory activity (FAA). In mammals, many studies have shown that FAA is driven by a food-entrained circadian oscillator (FEO) that is distinct from the light-entrained pacemaker in the suprachiasmatic nucleus of the hypothalamus. Few studies have investigated the effect of sugar ingestion on food anticipatory rhythms and the FEO. We aimed to extend the understanding of the role of glucose on the emergence of food anticipatory rhythms by investigating whether glucose ingestion is sufficient to produce daily food anticipation, reflected by motor activity and core body temperature rhythms. Under a 12 h/12 h light/dark cycle, chow-deprived rats had glucose solution available between Zeitgeber Time (ZT) 6 and ZT 9 for 10 days (glucose restriction group), whereas control animals had chow available within the same time window (chow restriction group). Animals in both groups exhibited anticipatory motor activity and body temperature around the fourth day of the scheduled food restriction. Glucose-fed rats ingested ~15 kcal on the days immediately before FAA emergence and reached an intake of ~20 kcal/day, whereas chow-fed rats ingested ~40 kcal/day. The glucose restriction group exhibited a pattern of food anticipation (activity and temperature) that was extremely similar to that observed in the chow restriction group. We conclude that glucose ingestion is a sufficient temporal cue to produce recurrent food anticipation, reflected by activity and temperature rhythms, in rats.
Avalia??o clínica e ecocardiográfica de pacientes submetidos a implante de bioprótese mitral com preserva??o da valva natural
Dias, Altamiro Ribeiro;Assump??o, Luiz F. P;Castanho, Volnei;Lomelino, Sérgio Mattos;Brito, Luiz Abba;Samuel, Osmar;Medeiros, Caio Cesar J;Catani, Cesar A. M;Parga Filho, José R;Chinelato, José Ant?nio;Jatene, Adib D;
Revista Brasileira de Cirurgia Cardiovascular , 1990, DOI: 10.1590/S0102-76381990000100004
Abstract: the preliminary postoperative results in 16 patients submitted to valvular replacement utilising bovine pericardial valvular bioprostheses, without resection of their natural cusps, are presented. these patients were operated on sequentially from march to september 1989. the incompetent cusps were sutured to the mitral annulus with u stitches placed at their free edges. pre and postoperative evaluation of the following parameters were obtained: left atrial diameters, left ventricular diameters, ejection fraction and mitral transvalvular gradients (peak and mean). statistical evaluation utilising the student's t test was performed. preoperative mean value of the left ventricular diameter was 67.31 mm, decreasing to 60.50 mm in the postoperative evaluation. critical value of t was 2.131, the value observed for the left ventricle variation being 3.18. the left atrial diameter varied from 60.25 mm to 49.31 mm (t equal to 6.72). preoperative ejection fraction mean value was 0.72 and in the postoperative was 0.65 (t = 2.68). mean transvalvular gradients varied from 23.7 mm (peak) and 12.5 mm (mean) to 9.10 and 5.125 respectively. these residual values are acceptable according to the current literature and the experience of our institution. there were no complications or deaths in the present series. in no patient gradients in the left ventricular out flow tract suggesting obstruction by the anterior cusp were observed. the authors consider it an efficient technique, easily and rapidly performed, without danger of atrioventricular desinsertions and without significant gradients. ventricular performance is enhanced and the left atrial and left ventricular diameters decrease considerably.
Gerenciamento de resultados em bancos com uso de TVM: valida o de modelo de dois estágios Securities-based earnings management in nanks: validation of a two-stage model
José Alves Dantas,Otávio Ribeiro de Medeiros,Fernando Caio Galdi,Fábio Moraes da Costa
Revista Contabilidade & Finan?as , 2013,
Abstract: Estudos sobre gerenciamento de resultados em bancos têm se preocupado especialmente com o uso da provis o para créditos de liquida o duvidosa (PCLD) e utilizam principalmente modelos de dois estágios para a identifica o da a o discricionária da administra o. Outro tipo de registro que tem recebido aten o dos pesquisadores na identifica o dessa prática em bancos é a classifica o e a mensura o do valor justo dos títulos e valores mobiliários (TVM). Nesse caso, porém, têm prevalecido modelos de um estágio. Este estudo tem por objetivo desenvolver e validar um modelo de dois estágios para a identifica o da discricionariedade nos resultados com TVM. O modelo incorpora preceitos dos poucos estudos sobre o tema, parametros utilizados nos modelos para identifica o da PCLD discricionária em bancos, além de indicadores macroecon micos e características específicas de composi o da carteira de TVM. Os testes empíricos tiveram por base as informa es dos bancos comerciais, bancos múltiplos e caixas econ micas em atua o no mercado brasileiro, entre o terceiro trimestre de 2002 e o quarto trimestre de 2010. Para a valida o do modelo proposto, os seus resultados foram cotejados com os decorrentes da aplica o de um modelo de um estágio - metodologia difundida na literatura sobre o tema. Os testes realizados com os dois modelos revelam evidências da prática de alisamento de resultados com o uso de TVM, bem como a utiliza o da classifica o em títulos disponíveis para venda nessas a es de gerenciamento. A consistência dos resultados encontrados nos dois modelos evidencia a valida o do modelo proposto, contribuindo para o desenvolvimento de pesquisas sobre o tema que se preocupem n o apenas em constatar se há a prática ou n o do gerenciamento, mas também associá-la a outras variáveis. Neste estudo, por exemplo, foi constatado que essa prática é mais relevante nos bancos de menor porte e nos controlados por capital privado. Studies investigating earnings management in banks have been particularly concerned with the use of Loan Loss Provisions (LLP) and mainly use two-stage models to identify discretionary management actions. Another type of record that has received attention from researchers in identifying discretionary management actions is the classification and measurement of the fair value of securities. In this case, however, one-stage models have prevailed. The present study aims to develop and validate a two-stage model for the identification of discretionary management actions using gains obtained from securities. Our model incorporates macroeconomic
Study of Coronary Sinus Flow Reserve Through Transesophageal Doppler Echocardiography in Normal Subjects
Ramos Filho José,Ramires José A. F.,Turina Marko,Medeiros Caio J.
Arquivos Brasileiros de Cardiologia , 2002,
Abstract: OBJECTIVE - To evaluate the Coronary Flow Reserve in the Coronary Sinus through transesophageal Doppler echocardiography in normal subjects. METHODS - We obtained technically adequate flow samples for analysis in 10 healthy volunteers (37±8 years, 5 men) with no history of heart or systemic disease and with mean left ventricular mass index by transthoracic echocardiography of 87±18 g/m2. Coronary sinus flow velocity was recorded within the coronary sinus with the patient in a resting condition and during intravenous adenosine infusion at a dose of 140 μg/kg/min for 4 minutes. Recording of coronary sinus blood flow was possible in all cases with measurement of peak systolic, diastolic, and retrograde velocities (PSV, PDV, and PRV, cm/sec), mean systolic and diastolic velocities (MSV and MDV, cm/sec), and systolic and diastolic velocity time integral (VTI S and VTI D, cm/sec). RESULTS - The coronary flow reserve was calculated as the ratio between the blood flow in the basal state and the maximum measured hyperemic blood flow with adenosine infusion. Results are shown as mean and standard deviations. (CFR = PSV + PDV -- PRV/basal PSV): 1st min = 2.2±0.21; 2nd min = 3±0.3; 3rd min = 3.4±0.37; 4th min = 3.6 ± 0.33. CONCLUSION - Although coronary sinus flow had significantly increased in the first minute, higher velocities were seen at third and fourth minutes, indicating that these should be the best times to study coronary sinus flow with intravenous adenosine in continuous infusion.
Study of Coronary Sinus Flow Reserve Through Transesophageal Doppler Echocardiography in Normal Subjects
Ramos Filho, José;Ramires, José A. F.;Turina, Marko;Medeiros, Caio J.;Lachat, Mário;Tsutsui, Jeane;
Arquivos Brasileiros de Cardiologia , 2002, DOI: 10.1590/S0066-782X2002001100001
Abstract: objective - to evaluate the coronary flow reserve in the coronary sinus through transesophageal doppler echocardiography in normal subjects. methods - we obtained technically adequate flow samples for analysis in 10 healthy volunteers (37±8 years, 5 men) with no history of heart or systemic disease and with mean left ventricular mass index by transthoracic echocardiography of 87±18 g/m2. coronary sinus flow velocity was recorded within the coronary sinus with the patient in a resting condition and during intravenous adenosine infusion at a dose of 140 μg/kg/min for 4 minutes. recording of coronary sinus blood flow was possible in all cases with measurement of peak systolic, diastolic, and retrograde velocities (psv, pdv, and prv, cm/sec), mean systolic and diastolic velocities (msv and mdv, cm/sec), and systolic and diastolic velocity time integral (vti s and vti d, cm/sec). results - the coronary flow reserve was calculated as the ratio between the blood flow in the basal state and the maximum measured hyperemic blood flow with adenosine infusion. results are shown as mean and standard deviations. (cfr = psv + pdv ? prv/basal psv): 1st min = 2.2±0.21; 2nd min = 3±0.3; 3rd min = 3.4±0.37; 4th min = 3.6 ± 0.33. conclusion - although coronary sinus flow had significantly increased in the first minute, higher velocities were seen at third and fourth minutes, indicating that these should be the best times to study coronary sinus flow with intravenous adenosine in continuous infusion.
Jamming transition in a two-dimensional open granular pile with rolling resistance
Caio F. M. Magalh?es,Allbens P. F. Atman,Ga?l Combe,José G. Moreira
Physics , 2014, DOI: 10.4279/PIP.060007
Abstract: We present a molecular dynamics study of the jamming/unjamming transition in two-dimensional granular piles with open boundaries. The grains are modeled by viscoelastic forces, Coulomb friction and resistance to rolling. Two models for the rolling resistance interaction were assessed: one considers a constant rolling friction coefficient, and the other one a strain dependent coefficient. The piles are grown on a finite size substrate and subsequently discharged through an orifice opened at the center of the substrate. Varying the orifice width and taking the final height of the pile after the discharge as the order parameter, one can devise a transition from a jammed regime (when the grain flux is always clogged by an arch) to a catastrophic regime, in which the pile is completely destroyed by an avalanche as large as the system size. A finite size analysis shows that there is a finite orifice width associated with the threshold for the unjamming transition, no matter the model used for the microscopic interactions. As expected, the value of this threshold width increases when rolling resistance is considered, and it depends on the model used for the rolling friction.
Reconstru??o geométrica do ventrículo esquerdo: avalia??o intraoperatória por ecocardiograma transesofágico
Jatene, Marcelo B;Moraes, álvaro;Jatene, Fábio B;Medeiros, Caio;Rezende, Marcos V;Dallan, Luís Alberto;Jatene, Adib D;
Revista Brasileira de Cirurgia Cardiovascular , 1993, DOI: 10.1590/S0102-76381993000400004
Abstract: the surgical treatment of lva by geometric reconstruction has been increasing the results and the use of tee is an important method to evaluate the results. from july 91 to january 92,22 consecutive patients (pts) with lva were operated on, 20 were male and the ages ranged from 35 to 72 y (57.1 y). all pts were operated on with extracorporeal circulation (ecc), moderate hypothermia and intermitent aortic crossclamping. the surgical technique consisted by plicatures of septal and antero-apical wall to reconstruct the lv cavity and 19 pts received bypass grafts. no deaths were observed and in 4 pts was used iabp with good evolution. the te evaluation was performed before and after the ecc in hemodinamic estability. some parameters were evaluated as: inferior wall thickning (wt) that was 30% pre ecc and 61 % post ecc (p<0.05). the ejection fraction varied from 25% pre ecc to 52% post ecc (p<0.05). the diastolic diameter came from 65 mm pre ecc to 53 mm post ecc (p<0.05). in conclusion, the geometric reconstruction of lva showed good results, confirmed by hemodynamic and echo parameters in intraoperative period.
Observations of atmospheric gravity waves using airglow all-sky CCD imager at Cachoeira Paulista, Brazil (23° S, 45° W)
A. F. Medeiros,H. Takahashi,P. P. Batista,D. Gobbi
Geofísica internacional , 2004,
Abstract: An all-sky CCD imager for OH, O2 and OI (557.7 nm) airglow was operated at Cachoeira Paulista (CP), Brazil, (23° S, 45° W), from October 1998 to September 1999, with Utah State University. Dominant gravity wave components are extracted and seasonal variations are investigated. These waves have typically short horizontal wavelengths (5 – 60 km), short periods (5 – 35 minutes), and horizontal phase speeds of 1 – 80 m/s. Band-type waves of horizontal wavelength between 10 and 60 km showed clear seasonal dependence in the horizontal propagation direction to southeast in summer and to northwest in winter. The direction of propagation changed in mid-March and at the end of September. The gravity waves over CP may be generated by the strong tropospheric convection. In summer, this region extends along a line approximately between (10° S, 45° W) and (40° S, 78° W), from northern Argentina to the Brazilian northeast, with an accentuated distribution over central Brazil. CP is below this region. In winter, the convective region is located below CP mainly over the sea and there is no convection in central Brazil region above CP. Thus the anisotropy of the wave propagation direction is mainly due to source location and wave filtering by stratospheric winds.
Controle estatístico aplicado ao processo de colheita mecanizada de cana-de-a?úcar
Silva, Rouverson P. da;Corrêa, Caio F.;Cortez, Jorge W.;Furlani, Carlos E. A.;
Engenharia Agrícola , 2008, DOI: 10.1590/S0100-69162008000200010
Abstract: the dvances in sugar cane mechanized harvest provided the management of new technologies and productivity gain to the crop. the control of quality process of sugar cane harvest is essential to reduce losses. however, studies regarding the subject are still scarce. this study aimed to evaluate the losses in the mechanized harvest of sugar cane, using them as markers of harvest quality process. the data was collected in two properties near jaboticabal - sp, brazil, on sp80-3280 variety, in 3rd and 4th cuts. the sugar cane plantation port was characterized, and, after the harvest, an area of 1.5 ha was marked, being 25 points, with row spacing of 12 x 50 m, quantifying the visible losses. later, the statistical process quality was applied by the average, which is three times higher or lower than the standard deviation, being these control limits superior and inferior, respectively. the loss average of untied piece was statistically higher than the loss average of fixed piece, whole cane, top and stubbles. the occurrence of losses of splinted stalks was lower for the fourth cut in relation to the third curt, whereas the losses of fixed piece and stubbles were lower in the third cut when compared to the losses in the fourth cut. in each cut, the averages of total losses were similar to the values found in bibliography. untied piece was the variable of visible losses with higher percentage of occurrence. the losses showed that the mechanized harvest is not under the statistical process control.
Antiproliferative activity of Eremanthus crotonoides extracts and centratherin demonstrated in brain tumor cell lines
Jonathas F. R. Lobo,Elaine S. Castro,Dayana R. Gouvea,Caio P. Fernandes
Revista Brasileira de Farmacognosia , 2012,
Abstract: The genus Eremanthus is recognized by the predominance of sesquiterpene lactones from the furanoheliangolide type, a class of substances extensively tested against cancer cell lines. Thus, the species E. crotonoides (DC.) Sch. Bip., Asteraceae, obtained on "restinga" vegetation was evaluated against U251 and U87-MG glioma cell lines using the MTT colorimetric assay. Dichloromethane fraction was cytotoxic to both glioblastoma multiforme cell lines. We then conducted UPLC-PDA-ESI-MS/MS analysis of the dichloromethane fraction, which allowed the identification of the sesquiterpene lactones centratherin and goyazensolide. The isolation of centratherin was performed using chromatographic techniques and the identification of this substance was confirmed according to NMR data. Cytotoxic activity of centratherin alone was also evaluated against both U251 and U87-MG cells, which showed IC50 values comparable with those obtained for the commercial anticancer drug doxorubicin. All the tested samples showed cytotoxic activity against glioblastoma multiforme cells which suggests that E. crotonoides extracts may be important sources of antiproliferative substances and that the centratherin may serve as prototype for developing new antiglioblastoma drugs.
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