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Search Results: 1 - 10 of 266173 matches for " CHEN De-Xin "
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Discussion about treatment of severe acute respiratory syndrome based on syndrome differentiation
YAN De-Xin
Zhong Xi Yi Jie He Xue Bao , 2004,
Abstract: Severe acute respiratory syndrome is an infectious disease caused by a new type of coronavirus. It belongs to the seasonal febrile diseases in traditional Chinese medicine. The prevention and treatment of severe acute respiratory syndrome (SARS) can be under the guidance of the doctrines for treating febrile diseases of traditional Chinese medicine, treatment based on syndrome differentiation, such as syndrome differentiation of triple energizer, syndrome differentiation according to defensive phase, qi phase, nutrient phase and blood phase. During April and May of 2003, 8 cases of SARS were diagnosed in Shanghai, and 6 patients accepted complementary therapy of traditional Chinese medicine, without death case. The only one patient who didn't take glucocorticoid therapy was complementarily treated with traditional Chinese herbs through the whole treating procedure. Upon the successful treatment of the eight cases of SARS in Shanghai, it is demonstrated that the triple-energizer syndrome differentiation and defensive-qi-nutrient-blood syndrome differentiation in traditional Chinese medicine are of high value in treating SARS patients.
Calibration Methods for the Multi-touch System Based on Four Collaborative Cameras

XIE Fei,CAI Shun,WANG De-xin,CHEN Chao,

计算机科学 , 2011,
Abstract: The multi touch system using four cameras solves the occlusion by fitting the four directing lines of each toueh point. This paper presented three methods to build the directing line, including look-up table method, vanishing point method and stereo calibration method. The look-up table method stations a set of reference points along the rectangle frame,finds the closest reference point by interpolation, and builds the line according to the projection center and the reference point; the vanishing point method builds the directing line according to the vanishing point of the touch point and the projection center; stereo calibration method builds the directing line according to epipolar geometry back projection line. Results show that look up table is applicable to small platforms and vanishing point method fits large size platforms while stereo calibration method needs to improve the precision.
Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery
Hong-Fang Ji, De-Xin Kong, Liang Shen, Ling-Ling Chen, Bin-Guang Ma, Hong-Yu Zhang
Genome Biology , 2007, DOI: 10.1186/gb-2007-8-8-r176
Abstract: By examining 2,186 well-defined small-molecule ligands and thousands of protein domains derived from a database of druggable binding sites, we show that a few ligands bind tens of protein domains or folds, whereas most ligands bind only one, which indicates that ligand-protein mapping follows a power law. Through assigning the protein-binding orders (early or late) for bio-ligands, we demonstrate that the preferential attachment principle still holds for the power-law relation between ligands and proteins. We also found that polar molecular surface area, H-bond acceptor counts, H-bond donor counts and partition coefficient are potential factors to discriminate ligands from ordinary molecules and to differentiate super ligands (shared by three or more folds) from others.These findings have significant implications for evolution and drug discovery. First, the chronology of ligand-protein binding can be inferred by the power-law feature of ligand-protein mapping. Some nucleotide-containing ligands, such as ATP, ADP, GDP, NAD, FAD, dihydro-nicotinamide-adenine-dinucleotide phosphate (NDP), nicotinamide-adenine-dinucleotide phosphate (NAP), flavin mononucleotide (FMN) and AMP, are found to be the earliest cofactors bound to proteins, agreeing with the current understanding of evolutionary history. Second, the finding that about 30% of ligands are shared by two or more domains will help with drug discovery, such as in finding new functions from old drugs, developing promiscuous drugs and depending more on natural products.Life is essentially a molecular network, not only in the individual sense but also at the ecosystem level [1,2]. The network depends greatly on the binding of small molecules (for example, ligands and cofactors) with macromolecules (for example, proteins). Small-molecule ligands not only participate in many basic enzymatic reactions (as coenzymes or substrates) to build metabolic networks, but also act as extra- and intra-cellular signals to help constru
An Approximate Optimal Damping Control Method for Nonlinear Time-delay Systems with Disturbances
De-xin Gao,Jingjing Wang
Journal of Software , 2010, DOI: 10.4304/jsw.5.9.934-941
Abstract: The optimal damping control for nonlinear time-delay systems with persistent disturbances is considered. Based on successive approximation approach (SAA), the optimal damping control (ODC) law is achieved by solving a decoupled sequence of inhomogeneous linear two-point boundary value (TPBV) problems without time-delay and time-advance terms. The ODC law of the original problem consists of accurate state feedback term, disturbance rejection term and a nonlinear time-delay compensation term, which is the limit of the adjoint vector sequence. By using the finite-time iteration of the compensation sequence, we can obtain an approximate optimal disturbance rejection control law. The proposed algorithms not only solve optimal control problems in the nonlinear time-delay system but also reduce the computation time and improve the precision. Numerical examples are included to illustrate the procedures.
Quantum-state transfer on spin-chain channels with random imperfection
De-Xin Kong,An Min Wang
Physics , 2009, DOI: 10.1140/epjd/e2009-00232-4
Abstract: We investigate the quantum-state transfer on spin-chian channels with random imperfections.Through combining the advantages of two known schemes, the dual-rail spin-chain channels[9] and the particular ihhomogenous spin-chain channel[10], we propose a protocol that can avoid the quantum noises introduced by many unnecessary measurements and can enhance the anti-decoherence ability. The results show that our protocol is more efficient to transfer an arbitrary quantum state than the original one. In particular, we discuss the effects of couplings fluctuations and imperfect initialization on both of the improved scheme and original one.
A Modified Particle Swarm Optimization Algorithm  [PDF]
Ai-Qin Mu, De-Xin Cao, Xiao-Hua Wang
Natural Science (NS) , 2009, DOI: 10.4236/ns.2009.12019
Abstract: Particle Swarm Optimization (PSO) is a new optimization algorithm, which is applied in many fields widely. But the original PSO is likely to cause the local optimization with premature convergence phenomenon. By using the idea of simulated annealing algo-rithm, we propose a modified algorithm which makes the most optimal particle of every time of iteration evolving continu-ously, and assign the worst particle with a new value to increase its disturbance. By the testing of three classic testing functions, we conclude the modified PSO algorithm has the better performance of convergence and global searching than the original PSO.
Isotope Evidence of Material Sources of the Dabaoshan Polymetallic Deposit

XU Wen-xin,LI Heng,CHEN Min-yang,HUANG De-xin,ZHANG FU-tie,WANG LI-ming,

地球学报 , 2008,
Abstract: 笔者对大宝山多金属矿床矿石和脉石矿物进行铅、硫、氢和氧同位素组成测定,获得硫化物的206Pb/204Pb值为17.930~18.785;207Pb/204Pb值为15.491~15.772;208Pb/204Pb值为37.990~40.990,并组成良好的线性关系。泥盆系地层中黄铁矿的δ34S为-22.5‰~+17.9‰,矿床硫化物的δ34S为-2.4‰~+4.6‰。黄铁矿、闪锌矿和方铅矿共生矿物对,具有δ34Spy>δ34Ssp>δ34Sgn,用磁黄铁矿的硫同位素组成估算出δ34S∑S为2‰±3‰。硫化物包裹体的氢同位素在-101‰~-123‰之间,与硫化物共生石英的氧同位素为+9.3‰~+17.9‰,换算成水的氧同位素为+0.3‰~+3.9‰,表明成矿热液来源较为复杂。
Causal agent of tobacco gray mould in Shaanxi Province and preventive effects of Trametes versicolor polysaccharides on the disease

LI Jin-Ling,LUO Jing,SHAN Hong-Ying,CHENG Ju-Long,CHEN De-Xin,AN De-Rong,

菌物学报 , 2013,
Abstract: 采用形态学观察和分子鉴定方法对2011年在陕西省发生的一种烟草未知病害的病原菌进行鉴定。从病叶组织分离纯化得到病原菌,通过致病性测定以及人工接种后再分离病菌,证明编号LJL007的菌株为该病的致病菌。依据病原菌的形态学和培养特征,将菌株LJL007鉴定为灰葡萄孢Botrytis cinerea Pers.,其有性型为富氏葡萄孢盘菌Botryotinia fuckeliana Whetzel。通过核糖体DNA ITS序列分析,分离菌株LJL007序列(登录号:HM17900)与富氏葡萄孢盘菌序列(登录号:HM849615)同源性达100%,进一步证明该病原菌是灰葡萄孢Botrytis cinerea。云芝多糖在离体条件下,对灰葡萄孢的菌丝生长和孢子萌发均无直接抑制作用。云芝多糖对烟草灰霉病有较好预防保护作用,其预防效果可达56.29%。云芝多糖可显著提高烟草体内几丁质酶和β-1,3-葡聚糖酶活性,其活性峰值分别比对照提高56.89%和429.83%,说明云芝多糖可诱导植物产生抗病性。
Development of a One-Step Immunocapture Real-Time RT-PCR Assay for Detection of Tobacco Mosaic Virus in Soil
Jin-Guang Yang,Feng-Long Wang,De-Xin Chen,Li-Li Shen,Yu-Mei Qian,Zhi-Yong Liang,Wen-Chang Zhou,Tai-He Yan
Sensors , 2012, DOI: 10.3390/s121216685
Abstract: Tobacco mosaic virus (TMV) causes significant losses in many economically important crops. Contaminated soils may play roles as reservoirs and sources of transmission for TMV. In this study we report the development of an immunocapture real-time RT-PCR (IC-real-time RT-PCR) assay for direct detection of TMV in soils without RNA isolation. A series of TMV infected leaf sap dilutions of 1:101, 1:102, 1:103, 1:104, 1:105 and 1:106 (w/v, g/mL) were added to one gram of soil. The reactivity of DAS-ELISA and conventional RT-PCR was in the range of 1:102 and 1:103 dilution in TMV-infested soils, respectively. Meanwhile, the detection limit of IC-real-time RT-PCR sensitivity was up to 1:106 dilution. However, in plant sap infected by TMV, both IC-real-time RT-PCR and real-time RT-PCR were up to 1:106 dilution, DAS-ELISA could detect at least 1:103 dilution. IC-real-time RT-PCR method can use either plant sample extracts or cultivated soils, and show higher sensitivity than RT-PCR and DAS-ELISA for detection of TMV in soils. Therefore, the proposed IC-real-time RT-PCR assay provides an alternative for quick and very sensitive detection of TMV in soils, with the advantage of not requiring a concentration or RNA purification steps while still allowing detection of TMV for disease control.
High Efficiency Expression of the Gene From Herpes Simplex Virus Type 1 (HSV-1) Glycoprotein D
Ⅰ型单纯疱疹病毒 gD基因片段的高效表达及抗原性分析

YI Jun-bo,LEI Ming-jun,CHEN Shao-juan,HUANG De-xin,LI Ling-yun,

中国生物工程杂志 , 2006,
Abstract: Objective:To obtain the high expression of Herpes Simplex Virus Type 1(HSV-1)Glycoprotein D gene. Methods:The Herpes Simplex Virus Type 1(HSV-1)Glycoprotein D(gD1) gene fragment containing dominant antigen epitopes confirmed by computer analysis was cloned by PCR technical and inserted into plasmid vector pTrxA. Then the recombinant plasmid was transformed into Rosetta. The expressed product was analyze by SDS-PAGE. Results:930 bp gene fragment was amplified by PCR as anticipated. Nucleotide sequencing showed a 100 % homology with that of the published sequence in GenBank. The molecular weight of the expressed protein was about 48kDa, Western blotting indicated that the antigenicity of the protein was good. Conclusion:The plasmid pTrxA-gd1 was constructed and a high efficiency expression of the gd1 gene from Herpes Simplex Virus Type 1(HSV-1)strain was made. The expressed product shows a good antigenicity.
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