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Antioxidant and antimicrobial activities of isolated constituents from the bark of Polyalthia longifolia
Bose Sankhadip,Byahatti Vivek,D′Souza Marina,Bose Arti
International Journal of Green Pharmacy , 2010,
Abstract: The bark of Polyalthia longifolia is traditionally reputed to lower blood pressure, stimulate respiration and help in fever and skin diseases, diabetes, hypertension and vitiated conditions of vata and pitta. Preliminary phytochemical investigation of various extracts of the bark of Polyalthia longifolia showed the presence of flavonoids, alkaloids, steroids and carbohydrates. An attempt has been made to isolate flavonoids and perform antioxidant and antimicrobial activity of the same. We carried out DPPH radical scavenging assay, nitric oxide scavenging assay, metal chelating activity and reducing power activity in antioxidant activity. In antimicrobial activity, we used six microorganisms, which included two Gram positive, two Gram negative bacteria and two fungi. Both the isolated flavonoids exhibited a concentration-dependant free radical scavenging capacity. Isolated compounds showed promising results against various micro-organisms in comparison with standard drugs (Penicillin, Gentamicin and Ketoconazol).
An insight into the swine-influenza A (H1N1) virus infection in humans
Dandagi Girish,Byahatti Sujata
Lung India , 2011,
Abstract: WHO declares on June 11, 2009, that H1N1 (Swine-influenza A) is pandemic. There have been nearly 30,000 confirmed H1N1 cases across 74 countries. The reports have shown sharp increase in the number of infections reported in recent days from Chile, Japan, and the UK, and other parts of the world, with the most dramatic increase recorded in Australia where more than 1200 cases were reported in a very short duration. As per the latest report of the Ministry of Health and Family Welfare, death from swine flu has reached to 1235. Around 12,3397 people have been tested in India as on February 1, 2010. In India, 23.3% of people who have tested for swine flu are found suffering from swine flu. Also around 4% of people who have tested positive for swine flu have died and could not be saved in India. The New York Times has reported that this is the first flu for being pandemic in the last 41 years. This article enlightens the brief review about the swine influenza virus, its modes of spread, and prevention measures. The aim of this article is to bring awareness in general and know the consequences of the infection.
An Improved Protocol for Biginelli Reaction  [PDF]
Vivek Srivastava
Green and Sustainable Chemistry (GSC) , 2013, DOI: 10.4236/gsc.2013.32A006
Abstract:

[Hmim][Tfa] was used as catalyst for the Biginelli reaction under microwave heating. Low catalyst loading, reduced reaction time and operational simplicity are the main highlights of this protocol. The proposed protocol was found active in the synthesis of 30 different biologically active compounds.

Assessment of diagnostic accuracy of high-resolution ultrasonography in determination of temporomandibular joint internal derangement
Byahatti Sujata,Ramamurthy B,Mubeen M,Agnihothri P
Indian Journal of Dental Research , 2010,
Abstract: Aim : The aim of this study was to determine the value of dynamic high-resolution ultrasonography (HR-US) in the evaluation of internal derangements of a temporomandibular joint (TMJ) in the open and closed mouth position. Settings and Design : The study designed to collect the sample from the Outpatient Department of Oral Medicine and Radiology at GDC, Bangalore. Patients with pain, clicking, deviation, and tenderness were included in the study as a symptomatic group. The asymptomatic group was free of any symptoms. Materials and Methods : Maximum mandibular range of motion (Open and Closed) was performed during HR-US of TMJ in 100 consecutive patients, (50 symptomatic and 50 asymptomatic cases, a total of 400 joints, with 200 joints in the right and left closed and open mouth position;36 males and 64 females; age range, 16 - 50 years; mean age 27.56 years). Subsequently, the entire group, after clinical diagnosis, went for HR-US. Sonography confirmed the diagnosis by showing internal derangement in 34 (68%) of the symptomatic group and the remaining 16 (32%) patients failed to show any derangement. In the asymptomatic group 40 patients did not show any pathology associated with TMJ, whereas, 10 patients showed internal derangement. The data obtained was analyzed statistically. Results : HR-US performed during the maximal range of motion (Open and Closed) helped to detect 34 instances (68 joints) of internal derangement, which were true positive cases, whereas, 16 patients (32 joints) showed a false positive finding for internal derangement (ID). The results obtained showed a sensitivity of 64%, specificity of 88%, positive predictive value of 84%, and a negative predictive value of 71%, with an accuracy of 76%. Conclusions : Dynamic HR-US being non-invasive can provide valuable information about internal derangement of the TMJ in mandibular closed mouth than open mouth position.
Neurosarcoidosis: An Illustrative Case and Review of Perioperative Considerations  [PDF]
Vivek Arora, Srilatha Mallu
Open Journal of Anesthesiology (OJAnes) , 2012, DOI: 10.4236/ojanes.2012.24038
Abstract: Sarcoidosis is a multisystem inflammatory granulomatous disease of unknown etiology. Neurosarcoidosis (NS) is a rare but potentially devastating manifestation of sarcoidosis, with a prevalence of approximately 5% in patients with systemic sarcoidosis. Due to the possible involvement of any part of the nervous system, a myriad of neurological manifestations can occur. Clinical features resulting from involvement of the hypothalmo-pituitary axis and cranial nerves, in particular, cranial nerve VII are the more common presentations of this condition. Medical therapy with corticosteroids is the mainstay of treatment and providing tissue for diagnosis remains the principal indication for surgery. Therapeutically, neurosurgery is indicated only for life-threatening complications. We describe the clinical case of a patient with fatally progressive NS who had multiple anesthetic exposures. This case highlights the perioperative considerations of NS and its anesthetic implications.
The Role of Global Civil Society in Global Governance  [PDF]
Vivek Kumar Mishra
Beijing Law Review (BLR) , 2012, DOI: 10.4236/blr.2012.34026
Abstract: Globalisation is the most defining feature of the twenty first century. The globalised world faces new challenges such as climate change, terrorism, poverty and economic crisis. These challenges having no borders and cannot be solved by any country alone. These can be resolved only by coordinated efforts at the global level. Therefore, the world needs more effective forms of collaboration between international organisations, governments, the private sector and global civil society. The paper is an attempt to elucidate the role of global civil society as a means of global governance for the resolution of many global issues. More particularly, the aim is to understand how global civil society organisations are shaping the processes of global governance, and what their implications might be for the quality of governance at the international level.
High Performance Polymer Light-Emitting Devices  [PDF]
Vivek Kant Jogi
World Journal of Nano Science and Engineering (WJNSE) , 2014, DOI: 10.4236/wjnse.2014.41003
Abstract:
In order to improve the performance of polymer light-emitting devices, driving voltages, current efficiency, luminance and power efficiency of different cathode metals such as Ca/Al, CsF/Al, LiF/Al and LiF/Ca/Ag were compared. The results show that cathode metals CsF/Al contain the highest current efficiency, maximum luminance and power efficiency. Therefore, we can choose the CsF/Al to be the cathode for improving the performance of polymer light-emitting devices.
Autologous Stem Cell Transplant for AL Amyloidosis
Vivek Roy
Bone Marrow Research , 2012, DOI: 10.1155/2012/238961
Abstract: AL amyloidosis is caused by clonal plasma cells that produce immunoglobulin light chains which misfold and get deposited as amyloid fibrils. Therapy directed against the plasma cell clone leads to clinical benefit. Melphalan and corticosteroids have been the mainstay of treatment for a number of years and the recent availability of other effective agents (IMiDs and proteasome inhibitors) has increased treatment options. Autologous stem cell transplant (ASCT) has been used in the treatment of AL amyloidosis for many years. It is associated with high rates of hematologic response and improvement in organ function. However, transplant carries considerable risks. Careful patient selection is important to minimize transplant related morbidity and mortality and ensure optimal patient outcomes. As newer more affective therapies become available the role and timing of ASCT in the overall treatment strategy of AL amyloidosis will need to be continually reassessed. 1. Introduction Amyloidosis is a disease of protein misfolding in which the involved protein acquires an abnormal beta-pleated sheet configuration rather than the native alpha helical state [1]. The amyloid protein is insoluble, and its deposition in various tissues causes tissue damage and organ dysfunction. Amyloidosis can be of various types based on the precursor protein involved in amyloid formation. More than 20 different human fibrillar amyloid proteins have been described [2], and accurate identification of the type is crucial to treatment planning. It is also important to distinguish localized from systemic amyloidosis since patients presenting with localized amyloidosis generally do not need systemic treatment. The most common type of systemic amyloidosis (primary amyloidosis or AL amyloidosis) is caused by production of immunoglobulin light chain or light chain fragment secondary to an underlying plasma cell dyscrasia. Other systemic amyloidoses (secondary amyloidoses) include AA amyloid (caused as a result of chronic inflammatory disease), ATTR caused by alteration in transthyretin (TTR) protein because of one of several mutations (familial amyloid) or misfolding of wild-type transthyretin protein (senile amyloidosis), and dialysis-related amyloidosis (deposition of beta 2 microglobulin). Primary amyloidosis is the only type of systemic amyloidosis that responds to cytotoxic chemotherapy directed against the abnormal plasma cell clone, the source of amyloidogenic light chains. Other treatment strategies to prevent amyloid formation by altering the equilibrium between soluble precursor and
?Revivir el Estado desarrollista? El mito de la "Burguesía Nacional"
Chibber,Vivek;
Documentos y aportes en administraci?3n p?oblica y gesti?3n estatal , 2008,
Abstract: the return to a kind of "developmentalism" is not only to be found among political elites, but also, emanates from the anti-globalization movement- -critical intellectuals, ngos, and trade unions, and appears to many to be the "transitional programme" of our time. defending a space for national capitalist development, under the direction of domestic groups, seems consistent with conscious direction of the economy--even if under the hegemony of the national bourgeoisie. nostalgia for the bygone era certainly understandable. but with a half-century of experience with just such models of development, which relied upon, and fostered the growth of, domestic capitalists. it may, therefore, be of some relevance to turn to the historical record, in order to examine closely the political preconditions for, and consequences of, developmentalist projects.
Connecting care competencies and culture during disasters
Chhabra Vivek
Journal of Emergencies, Trauma and Shock , 2009,
Abstract: Connecting care Competencies and Culture are core fundamentals in responding to disasters. Thick coordination between professionals, communities and agencies in different geographical areas is crucial to the happening of appropriate preparedness and thus efficient response and mitigation of a disaster. In the next few articles, we present diverse examples related to the preparedness and recovery process to adverse disasters across the globe
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