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Prevalence of Restless Legs Syndrome in Patients Treated with Peritoneal Dialysis: Clinical and Biochemical Characteristics among Patients with and without Restless Legs Syndrome  [PDF]
Selda Korkmaz, Bulent Tokgoz, Sevda Ismailogullari, Ismail Kocyigit, Merva Kocyigit, Ozgur Berkay Aksu, Murat Aksu
Open Journal of Nephrology (OJNeph) , 2013, DOI: 10.4236/ojneph.2013.31008
Abstract: Introduction and Aims:This is a prospective study identifying prevalence of Restless Legs Syndrome (RLS) in patients ongoing peritoneal dialysis (PD) due to end stage renal disease (ESRD) and comparing clinical and biochemical characteristics among patients with and without RLS. Methods: Two hundred ESRD patients who received PD at least six months assessed by neurologist and nephrologist with regards to presence of RLS. Also, clinical and biochemical features of these patients are determined. One hundred and forty four patients were excluded from study because they had other secondary causes of RLS except for ESRD. Results: Thirteen of 56 patients (23.2%) had RLS. The use of vitamin B + folic acid supplements was significantly lower in patients with RLS than in those without RLS (69.2% vs 97.7%; p = 0.008). There was no significant difference between patient groups with and without RLS in terms of age, gender, body mass index, cause of ESRD, peritoneal membrane transport characteristic, smoking, consuming alcohol, use of erythropoietin, duration of PD, hemoglobin, serum calcium, serum phosphorus, serum albumin, levels of serum iron, total iron binding capacity, ferritin, folic acid and vitamin B12, transferrin saturation, weekly Kt/V urea value, and amount of residual urine volume (p > 0.05). Conclusion: RLS is more common among PD patients than general population. Although essential cause is not exactly known, use of folic acid and vitamin B complex decrease the RLS prevalence in this particular patient group.
Unusual Clinical Presentation of Ethylene Glycol Poisoning: Unilateral Facial Nerve Paralysis
Eray Eroglu,Ismail Kocyigit,Sami Bahcebasi,Aydin Unal,Murat Hayri Sipahioglu,Merva Kocyigit,Bulent Tokgoz,Oktay Oymak
Case Reports in Medicine , 2013, DOI: 10.1155/2013/460250
Abstract: Ethylene glycol (EG) may be consumed accidentally or intentionally, usually in the form of antifreeze products or as an ethanol substitute. EG is metabolized to toxic metabolites. These metabolites cause metabolic acidosis with increased anion gap, renal failure, oxaluria, damage to the central nervous system and cranial nerves, and cardiovascular instability. Early initiation of treatment can reduce the mortality and morbidity but different clinical presentations can cause delayed diagnosis and poor prognosis. Herein, we report a case with the atypical presentation of facial paralysis, hematuria, and kidney failure due to EG poisoning which progressed to end stage renal failure and permanent right peripheral facial nerve palsy. 1. Introduction Ethylene glycol (EG) may be consumed accidentally or intentionally, usually in the form of antifreeze products or as an ethanol substitute. It is converted by alcohol dehydrogenase to active metabolites in the liver, and these metabolites cause metabolic acidosis with increased anion gap, renal failure, hypocalcemia, oxaluria, and damage to the central nervous system and cranial nerves [1–3]. Diagnosis of EG poisoning could be a challenge due to altered mental status and lack of poisoning history. While metabolic acidosis with increased anion gap is common, osmolar gap resolves within 24 to 72 hours as the EG is metabolized to toxic metabolites. Early initiation of treatment can reduce the mortality, and morbidity but different presentations especially with delayed cases could be a problem, so patients with acute renal failure require more attention [4]. In cases of renal failure with the suspicion of EG poisoning, kidney biopsy should be considered promptly. Histological examination of renal tissue often reveals widespread necrosis of the tubular epithelium and deposition of a multitude of doubly refractile oxalate crystals in the distal tubules and collecting ducts [5, 6]. Herein, we report a case with the atypical presentation of facial paralysis, hematuria, and kidney failure due to EG poisoning. 2. Case Report A 25-year-old man was admitted to the emergency department of our university hospital with sudden onset of nausea, vomiting, slight mental disability, and abdominal pain. Cardiovascular, respiration, and gastrointestinal system examination findings were normal. The neurological examinations of the cranial nerves and limbs were normal. He was clinically dehydrated. On the first day of his admission, laboratory studies revealed a BUN level of 35?mg/dL, creatinine level of 3.17?mg/dL, calcium level of
Resonance Spectra of Caged Stringy Black Hole and Its Spectroscopy
I. Sakalli,G. Tokgoz
Physics , 2015, DOI: 10.1155/2015/739153
Abstract: The Maggiore's method (MM), which evaluates the transition frequency that appears in the adiabatic invariant from the highly damped quasinormal mode (QNM) frequencies, is used to investigate the entropy/area spectra of the Garfinkle--Horowitz--Strominger black hole (GHSBH). Instead of the ordinary QNMs, we compute the boxed QNMs (BQNMs) that are the characteristic resonance spectra of the confined scalar fields in the GHSBH geometry. For this purpose, we assume that the GHSBH has a confining cavity (mirror) placed in the vicinity of the event horizon. We then show how the complex resonant frequencies of the caged GHSBH are computed using the Bessel differential equation that arises when the scalar perturbations around the event horizon are considered. Although the entropy/area is characterized by the GHSBH parameters, their quantization is shown to be independent of those parameters. However, both spectra are equally spaced.
The effect of propofol lipuro with and without lidocaine on infection pain in Children
SG Beyaz, A Tufek, O Tokgoz
Nigerian Journal of Clinical Practice , 2011,
Meat Consumption and Buying Behaviors of Consumers Living in Manisa City Center, Turkey
Bulent Ergonul
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2011.286.290
Abstract: This study presents results of the data analysis and the results of a consumer questionnaire of 41 questions into meat and meat products carried out in Manisa city center among September 2008 and May 2009. Responds of 1200 consumers from different ages, genders and jobs were analyzed. Survey showed that despite recent food tendencies and new consumption behaviors, consumers living in Manisa still prefer red meat to poultry meat and fish. Also data related to consumption frequencies of meat kinds and meat products were conducted in the study.
Health Manpower Planning and Employment Policies for Turkey
Bulent Kilic
TAF Preventive Medicine Bulletin , 2007,
Abstract: Health manpower planning in health care should be done strategically while considering the following factors: health care needs and demands for community, health care organizations' objectives, goals and resources, goal of a high quality health workforce of sufficient size which has been appropriately distributed, their full employment realized within the appropriate time frame. A good health manpower planning consists of eight components: quantity (size), quality (skill), distribution, timing, employment, necessity, goals and resources. According to the calculations in this article, it must be 1515 people per general practitioner (GP) and 1333 people per midwife. There must be 44.755 GP and 50.866 midwife for primary level in Turkey. However there are 51.530 GP and 41.513 midwife in Turkey in 2002. In this situation there is no more need for GP but there is a big need for 10.000 midwife as totally and actually 30.000 midwife for working at health centres for Turkey. As a result, this article discusses the shortcomings of Health Ministry's employment policies in Turkey. It is suggested that in the short run concepts such as physician unemployment, under-employment and flexible work hours will become frequently discussed in Turkey health care public discourse. [TAF Prev Med Bull. 2007; 6(6): 501-514]
Could Microchimerism be an Etiological Factor in Psychotic Disorders? A Hypothetical Suggestion
Bulent Demirbek
Psikiyatride Guncel Yaklasimlar , 2010,
Abstract: In this letter to the editor, a possible etiologic relationship between microchimerism and psychotic disorders has been hypothezied and several study proposals that could be used in the testing of this hypothesis has been suggested.
The bad, the poor but alive
Bulent Mutlu
Anadolu Kardiyoloji Dergisi , 2008,
47 Year Old Patient with Pseudo-Asthma
Bulent Altinsoy
Oman Medical Journal , 2011,
Abstract: 47- year- old female patient presented in out-patient department in Afyon Chest Disease Hospital with dyspnea, cough and purulent sputum. She has been receiving regular inhaler β-agonist and corticosteroids with the diagnosis of asthma bronchial since childhood. However, the patient had a history of very often upper and lower respiratory tract infections. The patient did not smoke, drink alcohol, or use illicit drugs intravenously. She was currently on asthma medications.
Protective Effect of Melatonin on Streptozotocin-induced Diabetes in Mice
Bulent Gunduz
Journal of Medical Sciences , 2001,
Abstract: The research work was conducted to investigate the effects of melatonin on streptozotocin (STZ)-induced diabetes in mice. Mice were divided into six groups. The first two groups were STZ injected animals. The other four groups, were STZ plus melatonin injected. The melatonin doses were 50 or 500μg kg-1 respectively. Plasma glucose level, body weights and insulates were examined. The plasma glucose levels were significantly higher only in STZ-injected mice. No significant difference was seen in the plasma glucose content of STZ plus melatonin 50 and 500μg kg-1 groups. Mononuclear cell infiltration of pancreatic islets (insulates) was much more intensive only in STZ injected mice.These results suggested that when melatonin is injected at the same time with STZ, it acts to prevent the development of diabetes in experimental mice.
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