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Search Results: 1 - 10 of 301702 matches for " Brian P. O'Connor "
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Applying Complexity Theory to a Dynamical Process Model of the Development of Pathological Belief Systems
Brian P. O'Connor,Liane Gabora
Physics , 2013,
Abstract: A general dynamical process model of psychiatric disorders is proposed that specifies the basic cognitive processes involved in the transition from beliefs about self, others and world that are normal and adaptive, to beliefs that are rigid, extreme, and maladaptive. The relevant thought trajectories are self-confirming, and are considered to underlie the corresponding trajectories in symptoms. In contrast with previous work, the model focuses on underlying mechanisms, and it provides an evolutionary basis for the widespread susceptibility to psychiatric symptoms and disorders without the problematic claim that such disorders were selected by evolutionary forces. The model thereby incorporates both normality and abnormality in the same framework.
Matrix $φ^4$ Models on the Fuzzy Sphere and their Continuum Limits
Brian P. Dolan,Denjoe O'Connor,P. Presnajder
Physics , 2001, DOI: 10.1088/1126-6708/2002/03/013
Abstract: We demonstrate that the UV/IR mixing problems found recently for a scalar $\phi^4$ theory on the fuzzy sphere are localized to tadpole diagrams and can be overcome by a suitable modification of the action. This modification is equivalent to normal ordering the $\phi^4$ vertex. In the limit of the commutative sphere, the perturbation theory of this modified action matches that of the commutative theory.
Matrix models on the fuzzy sphere
Brian P. Dolan,Denjoe O'Connor,Peter Presnajder
Physics , 2002,
Abstract: Field theory on a fuzzy noncommutative sphere can be considered as a particular matrix approximation of field theory on the standard commutative sphere. We investigate from this point of view the scalar $\phi^4$ theory. We demonstrate that the UV/IR mixing problems of this theory are localized to the tadpole diagrams and can be removed by an appropiate (fuzzy) normal ordering of the $\phi^4$ vertex. The perturbative expansion of this theory reduces in the commutative limit to that on the commutative sphere.
Scalar and Spinor Field Actions on Fuzzy $S^4$: fuzzy $CP^3$ as a $S^2_F$ bundle over $S^4_F$
Julieta Medina,Idrish Huet,Denjoe O'Connor,Brian P. Dolan
Physics , 2012, DOI: 10.1007/JHEP08(2012)070
Abstract: We present a manifestly Spin(5) invariant construction of squashed fuzzy $CP^3$ as a fuzzy $S^2$ bundle over fuzzy $S^4$. We develop the necessary projectors and exhibit the squashing in terms of the radii of the $S^2$ and $S^4$. Our analysis allows us give both scalar and spinor fuzzy action functionals whose low lying modes are truncated versions of those of a commutative $S^4$.
Critical Behaviour of the Fuzzy Sphere
Denjoe O'Connor,Brian P. Dolan,Martin Vachovski
Physics , 2013, DOI: 10.1007/JHEP12(2013)085
Abstract: We study a multi-matrix model whose low temperature phase is a fuzzy sphere that undergoes an evaporation transition as the temperature is increased. We investigate finite size scaling of the system as the limiting temperature of stability of the fuzzy sphere phase is approached. We find on theoretical grounds that the system should obey scaling with specific heat exponent \alpha=1/2, shift exponent \bar \lambda=4/3 and that the peak in the specific heat grows with exponent \bar \omega=2/3. Using hybrid Monte Carlo simulations we find good collapse of specific heat data consistent with a scaling ansatz which give our best estimates for the scaling exponents as \alpha=0.50 \pm 0.01,\bar \lambda=1.41 \pm 0.08 and \bar \omega=0.66 \pm 0.08 .
Fuzzy Complex Quadrics and Spheres
Brian P. Dolan,Denjoe O'Connor,Peter Presnajder
Mathematics , 2003, DOI: 10.1088/1126-6708/2004/02/055
Abstract: A matrix algebra is constructed which consists of the necessary degrees of freedom for a finite approximation to the algebra of functions on the family of orthogonal Grassmannians of real dimension 2N, known as complex quadrics. These matrix algebras contain the relevant degrees of freedom for describing truncations of harmonic expansions of functions on N-spheres. An Inonu-Wigner contraction of the quadric gives the co-tangent bundle to the commutative sphere in the continuum limit. It is shown how the degrees of freedom for the sphere can be projected out of a finite dimensional functional integral, using second-order Casimirs, giving a well-defined procedure for construction functional integrals over fuzzy spheres of any dimension.
The Recognizability of Individual Creative Styles Within and Across Domains
Liane Gabora,Brian P. O'Connor,Apara Ranjan
Quantitative Biology , 2013,
Abstract: We present a set of studies that tested the hypothesis that creative style is recognizable within and across domains. Art students were shown two sets of paintings, the first by five famous artists and the second by their art student peers. For both sets, they guessed the creators of the works at above-chance levels. In a similar study, creative writing students guessed at above-chance levels which passages were written by which of five famous writers, and which passages were written by which of their writing student peers. When creative writing students were asked to produce works of art, they guessed at above-chance levels which of their peers produced which artwork. Finally, art students who were familiar with each other's paintings guessed at above-chance levels which of their peers produced which non-painting artwork. The findings support the hypothesis that creative styles are recognizable not just within but also across domains. We suggest this is because all of an individual's creative outputs are expressions of a particular underlying uniquely structured self-organizing internal model of the world.
Fuzzy Complex Projective Spaces and their Star-products
A. P. Balachandran,Brian P. Dolan,J. Lee,X. Martin,Denjoe O'Connor
Mathematics , 2001, DOI: 10.1016/S0393-0440(02)00020-7
Abstract: We derive an explicit expression for an associative *-product on fuzzy complex projective spaces. This generalises previous results for the fuzzy 2-sphere and gives a discrete non-commutative algebra of functions on fuzzy complex projective spaces, represented by matrix multiplication. The matrices are restricted to ones whose dimension is that of the totally symmetric representations of SU(N). In the limit of infinite dimensional matrices we recover the commutative algebra of functions on ordinary projective space. Derivatives on the fuzzy projective space are also expressed as matrix commutators.
Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis
Brian D Gelbman, Adriana Heguy, Timothy P O'Connor, Joseph Zabner, Ronald G Crystal
Respiratory Research , 2007, DOI: 10.1186/1465-9921-8-10
Abstract: Microarray analysis of airway epithelium obtained by bronchoscopy on matched cohorts of 13 phenotypically normal smokers and 9 non-smokers was used to identify specific genes modulated by smoking that were associated with apoptosis. Among the up-regulated apoptotic genes was pirin (3.1-fold, p < 0.002), an iron-binding nuclear protein and transcription cofactor. In vitro studies using human bronchial cells exposed to cigarette smoke extract (CSE) and an adenovirus vector encoding the pirin cDNA (AdPirin) were performed to test the direct effect of cigarette smoke on pirin expression and the effect of pirin expression on apoptosis.Quantitative TaqMan RT-PCR confirmed a 2-fold increase in pirin expression in the airway epithelium of smokers compared to non-smokers (p < 0.02). CSE applied to primary human bronchial epithelial cell cultures demonstrated that pirin mRNA levels increase in a time-and concentration-dependent manner (p < 0.03, all conditions compared to controls).Overexpression of pirin, using the vector AdPirin, in human bronchial epithelial cells was associated with an increase in the number of apoptotic cells assessed by both TUNEL assay (5-fold, p < 0.01) and ELISA for cytoplasmic nucleosomes (19.3-fold, p < 0.01) compared to control adenovirus vector.These observations suggest that up-regulation of pirin may represent one mechanism by which cigarette smoke induces apoptosis in the airway epithelium, an observation that has implications for the pathogenesis of cigarette smoke-induced diseases.Although the airway epithelium has several defense mechanisms that respond to the stress imposed by cigarette smoke, in some individuals these defenses are exaggerated, resulting in chronic inflammation, and eventually, chronic bronchitis [1-5]. One of the earliest effects of cigarette smoke on the airway epithelium is to disrupt the protective barrier that is normally mediated by tight junctions between epithelial cells, resulting in increased permeability across
A new approach to physical activity maintenance: Rationale, design, and baseline data from the Keep Active Minnesota trial
Nancy E Sherwood, Brian C Martinson, A Lauren Crain, Marcia G Hayes, Nicolaas P Pronk, Patrick J O'Connor
BMC Geriatrics , 2008, DOI: 10.1186/1471-2318-8-17
Abstract: The Keep Active Minnesota Trial is a randomized controlled trial of an interactive phone- and mail-based intervention to help 50–70 year old adults who have recently increased their physical activity level, maintain that activity level over a 24-month period in comparison to usual care. Baseline, 6, 12, and 24 month measurement occurred via phone surveys with kilocalories expended per week in total and moderate-to-vigorous physical activity (CHAMPS Questionnaire) as the primary outcome measures. Secondary outcomes include hypothesized mediators of physical activity change (e.g., physical activity enjoyment, self-efficacy, physical activity self-concept), body mass index, and depression. Seven day accelerometry data were collected on a sub-sample of participants at baseline and 24-month follow-up.The Keep Active Minnesota study offers an innovative approach to the perennial problem of physical activity relapse; by focusing explicitly on physical activity maintenance, the intervention holds considerable promise for modifying the typical relapse curve. Moreover, if shown to be efficacious, the use of phone- and mail-based intervention delivery offers potential for widespread dissemination.ClinicalTrials.gov Identifier: NCT00283452.Despite substantial data documenting the health benefits of physical activity [1-18], sedentary behavior remains a significant public health problem that is particularly prevalent among older adults. The 2005 Behavioral Risk Factor Surveillance System (BRFSS) documents that among adults age 45–54, more than half (52%) were obtaining less than recommended levels of physical activity, with the same being true for 55% of adults age 55–64 [19]. With a few exceptions [20,21], most intervention efforts have remained focused on PA initiation [22-32]. However, since ongoing participation in PA is necessary to sustain health benefits, complementary strategies to increase the number of sedentary individuals who initiate PA and efforts to increase the n
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