oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Search Results: 1 - 2 of 2 matches for " Bongkod Jitjuk "
All listed articles are free for downloading (OA Articles)
Page 1 /2
Display every page Item
A phase I trial of Gynostemma pentaphyllum Makino in healthy volunteers
Pranee Chavalittumrong,Busarawan Sriwanthana,Rungrueng Kijphati,Bongkod Jitjuk
Songklanakarin Journal of Science and Technology , 2007,
Abstract: We conducted a phase I trial of Gynostemma pentaphyllum, grown in northern Thailand, to evaluate its safety in three groups of healthy volunteers. Fourteen, fifteen and fourteen volunteers respectively received the water extract of G. pentaphyllum in capsules at the doses of 50, 200 and 400 mg twice daily for two months. There were no major adverse events reported from any of the three groups throughout the study. Significant changes in hematological parameters, natural killer cell activities and the numbers of CD3+, CD4+ and CD8+ cells were not seen during taking the extract. Some biochemical parameters were significantly different from baseline data. Those values were, however, within normal limits and did not result in clinically significant conditions. Our results suggested that the water extract of G. pentaphyllum at the doses of 50, 200 or 400 mg twice daily given to healthy volunteers for two months was safe.
In vitro effects of Thai medicinal plants on human lymphocyte activity
Busarawan Sriwanthana,Weena Treesangsri,Bongkod Boriboontrakul,Somchit Niumsakul
Songklanakarin Journal of Science and Technology , 2007,
Abstract: We assessed the effects of Cleistocalyx nervosum var paniala, Gynostemma pentaphyllum, Gynura procumbens, Houttuynia cordata, Hyptis suaveolens, Portulaca grandiflora, Phytolacca americana and Tradescantia spathacea on lymphocyte proliferation and the effects of C. nervosum, G. pentaphyllum, H. suaveolens and P. grandiflora on natural killer (NK) cells activity. All of the extracts significantly stimulated human lymphocyte proliferative responses at various concentrations depending on each extract. The extracts of C. nervosum and H. suaveolens were significantly enhanced NK cells activity while those of G. pentaphyllum and P. grandiflora did not alter NK cells function. Our results suggested that the extracts of those plants have stimulating activity on human lymphocytes and could be clinically useful for modulating immune functions of the body.
Page 1 /2
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.