oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Search Results: 1 - 9 of 9 matches for " Bigarella "
All listed articles are free for downloading (OA Articles)
Page 1 /9
Display every page Item
Nota s?bre os depósitos arenosos recentes do litoral sul-brasileiro
Bigarella, Jo?o José;
Boletim do Instituto Oceanográfico , 1954, DOI: 10.1590/S0373-55241954000100010
Abstract: in this paper the author studies some sand samples from the coastal plain and beaches of south brazil. he modifies the former opinion about the origin of the hard and brown layers of sand, before named by him mangrovito. he suggests the action of the underground water rich in organic matter as being responsible for the hardening of the ancient shore sands.
Contribui??o ao Estudo da Planície Litoranea do Estado do Paraná
Bigarella, Jo?o José;
Brazilian Archives of Biology and Technology , 2001, DOI: 10.1590/S1516-89132001000500005
Abstract: the present paper contains an approach to systematize the study of the state of paraná coastal plains, in the southern part of brazil. it contains in general some geographical and geological data, documented by maps, sketches and photographs. in the initial stage the coastal plain represents a marine ingression, caused by faulting. this ingression penetrated the valleys of a not yet determinated geological landscape. ended the movement of deeping by faulting begins the epirogenic ascension and building of the barriers and beach ridges. an intensive sedimentation caused the lagoons and bays obstruction. this work refers mainly to t33 he sedimentary formations and the coastal plains is classified in the following way for the study in consideration to the morphology and origin: marine sedimentation - shore, barrier and beach ridge; intermediary sedimentation - mangrove swamps, mud and sand banks and mangrovito; continental sedimentation - dunes and terrestrial alluvion. there are also presented some data about the rocky coast and vegetation.
Contribui o ao Estudo da Planície Litoranea do Estado do Paraná
Bigarella Jo?o José
Brazilian Archives of Biology and Technology , 2001,
Abstract: The present paper contains an approach to systematize the study of the State of Paraná coastal plains, in the southern part of Brazil. It contains in general some geographical and geological data, documented by maps, sketches and photographs. In the initial stage the coastal plain represents a marine ingression, caused by faulting. This ingression penetrated the valleys of a not yet determinated geological landscape. Ended the movement of deeping by faulting begins the epirogenic ascension and building of the barriers and beach ridges. An intensive sedimentation caused the lagoons and bays obstruction. This work refers mainly to t33 he sedimentary formations and the coastal plains is classified in the following way for the study in consideration to the morphology and origin: Marine sedimentation - shore, barrier and beach ridge; Intermediary sedimentation - mangrove swamps, mud and sand banks and mangrovito; Continental sedimentation - dunes and terrestrial alluvion. There are also presented some data about the rocky coast and vegetation.
A study of convective flux schemes for aerospace flows
Bigarella, Enda Dimitri V.;Azevedo, Jo?o Luiz F.;
Journal of the Brazilian Society of Mechanical Sciences and Engineering , 2012, DOI: 10.1590/S1678-58782012000300012
Abstract: this paper presents the effects of some convective flux computation schemes on boundary layer and shocked flow solutions. second-order accurate centered and upwind convective flux computation schemes are discussed. the centered jameson scheme, plus explicitly added artificial dissipation terms are considered. three artificial dissipation models, namely a scalar and a matrix version of a switched model, and the cusp scheme are available. some implementation options regarding these methods are proposed and addressed in the paper. for the upwind option, the roe flux-difference splitting scheme is used. the cusp and roe schemes require property reconstructions to achieve second-order accuracy in space. a multidimensional limited muscl interpolation method is used to perform property reconstruction. extended multidimensional limiter formulation and implementation are here proposed and verified. theoretical flow solutions are used in order to provide a representative testbed for the current study. it is observed that explicitly added artificial dissipation terms of the centered scheme may nonphysically modify the numerical solution, whereas upwind schemes seem to better represent the flow structure.
Normal force calculations for rocket-like configurations
Bigarella, E. D. V.;Azevedo, J. L. F.;Mello, O. A. F.;
Journal of the Brazilian Society of Mechanical Sciences and Engineering , 2004, DOI: 10.1590/S1678-58782004000300005
Abstract: transonic and supersonic flow simulations over typical launch vehicle configurations are presented. a 3-d finite difference numerical code, written for general, curvilinear, body-conforming coordinate systems, is used. the code solves the thin-layer approximation for the laminar navier-stokes equations. simulations are performed for a launcher and a sounding rocket configurations, currently under development at instituto de aeronáutica e espa?o. calculations consider cases at angle of attack and at various freestream mach numbers. normal force coefficients are obtained such that the loads required for the design phase can be determined. computational results are compared to available experimental data. in general, good results within engineering error margins are obtained.
Adherens junctions connect stress fibres between adjacent endothelial cells
Jaime Millán, Robert J Cain, Natalia Reglero-Real, Carolina Bigarella, Beatriz Marcos-Ramiro, Laura Fernández-Martín, Isabel Correas, Anne J Ridley
BMC Biology , 2010, DOI: 10.1186/1741-7007-8-11
Abstract: We report that endothelial cell-cell junctions can attach to the ends of stress fibres instead of to cortical F-actin, forming structures that we name discontinuous adherens junctions (AJ). Discontinuous AJ are highly dynamic and are increased in response to tumour necrosis factor (TNF)-α, correlating with the appearance of stress fibres. We show that vascular endothelial (VE)-cadherin/β-catenin/α-catenin complexes in discontinuous AJ are linked to stress fibres. Moreover, discontinuous AJ connect stress fibres from adjacent cells independently of focal adhesions, of which there are very few in confluent endothelial cells, even in TNF-α-stimulated cells. RNAi-mediated knockdown of VE-cadherin, but not zonula occludens-1, reduces the linkage of stress fibres to cell-cell junctions, increases focal adhesions, and dramatically alters the distribution of these actin cables in confluent endothelial cells.Our results indicate that stress fibres from neighbouring cells are physically connected through discontinuous AJ, and that stress fibres can be stabilized by AJ-associated multi-protein complexes distinct from focal adhesions.Endothelial cell-cell junctions maintain endothelial integrity and regulate vascular morphogenesis. A major role of the vascular endothelium is to control the movement of small solutes and leukocytes in and out of the bloodstream. Endothelial junctions consist of several different multi-protein complexes, whose relative abundance and roles in regulating permeability and leukocyte diapedesis depend on the endothelial cell type. Endothelial adherens junctions (AJ) and tight junctions (TJ) are the main regulators of paracellular permeability in the endothelium. Some junctional proteins unique to endothelial cells, including PECAM-1, ICAM-2 and S-endo I, also contribute to endothelial barrier function [1]. In endothelial AJ, the transmembrane vascular endothelial (VE)-cadherin binds the cytoplasmic proteins β-catenin and p120-catenin. β-catenin also bi
Cognitive functions of epileptic patients on monotherapy with phenobarbitone and healthy controls
Bigarella, M?nica M.;M?der, Maria J.;Doro, Maribel P.;Gorz, Ana M.;Marcourakis, Tania;Tsanaclis, Lolita;Bittencourt, Paulo R. M.;
Arquivos de Neuro-Psiquiatria , 1991, DOI: 10.1590/S0004-282X1991000200003
Abstract: quantitative measurements have indicated that heredity, cerebral damage, psycho-social aspects, ictal and inter-ictal phenomena and antiepileptic drugs may interfere in the cognitive dysfunction of epileptic patients. in the present study objective methods included immediate and late recall and recognition of pictures, stroop test and auditory selection. twenty patients with symptomatic localized epilepsy aged 17-52 years (27±10, mean ±sd) were compared to age and socially matched healthy controls. patients were on therapeutic serum concentrations (25±12 m/mi) of phenobarbitone and had active epilepsy with 1.94 generalized tonic-clonic, 0.85 simple partial and 6.28 complex partial seizures monthly (means). patients performed worse than controls in all 6 tests (p<0.05 to p<0.001), indicating a generalized cognitive deficit related to seizures and/or barbiturate therapy. we suggest further studies should be carried out in populations with uniform monotherapeutic regimens and epileptic syndromes in order to isolate factors related to the cognitive dysfunction of epileptic patients.
Cognitive functions, epileptic syndromes and antiepileptic drugs
Bittencourt, Paulo R. M.;Mader, Maria Joana;Bigarella, Monica M.;Dóro, Maribel P.;Gorz, Ana M.;Marcourakis, Tania M.;Ferreira, Zulma S.;
Arquivos de Neuro-Psiquiatria , 1992, DOI: 10.1590/S0004-282X1992000100005
Abstract: cognitive function of patients on monotherapy specific for their epileptic syndrome has been studied infrequently. we evaluated 7 patients with symptomatic localised epilepsies (sel) on phenytoin aged 30±12 (mean±standard deviation) years, 8 with idiopathic generalised epilepsies on sodium valproate aged 18±4 years, 16 with sel on carbamazepine aged 28±11 years, and 35 healthy controls aged 27±11 years. all subjects were of normal intelligence, educated appropriately to age, and led productive lives in the community. two of the patients on carbamazepine and one on valproate had less than five partial, absence or myoclonic seizures monthly, the remaining were controlled. carbamazepine serum concentrations were 12±5 ug/ml, phenytoin were 23±7, and valproate were 62±23 (mean±sd). tests included immediate recall and recognition for pictures, stroop test, delayed recall and recognition of pictures. patients on phenytoin and valproate performed significantly worse than controls on immediate recall, and patients on carbamazepine performed significantly worse than controls in stroop test (p<0,01). the results indicate relatively minor effects of the epileptic syndromes and of phenytoin, carbamazepine and valproate on cognition of patients with controlled epilepsy leading productive lives in the community. we conclude that the cognitive deficit found in chronic epileptic patients on polytherapeutic drug regimen must be multifactorial, and that future studies need to control for all possible variables in order to achieve meaningul results.
CXCR7 Is Highly Expressed in Acute Lymphoblastic Leukemia and Potentiates CXCR4 Response to CXCL12
Rita de Cássia Carvalho Melo, Ana Leda Longhini, Carolina Louz?o Bigarella, Mariana Ozello Baratti, Fabiola Traina, Patrícia Favaro, Paula de Melo Campos, Sara Teresinha Olalla Saad
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0085926
Abstract: Recently, a novel CXCL12-binding receptor, has been identified. This CXCL12-binding receptor commonly known as CXCR7 (CXC chemokine receptor 7), has lately, based on a novel nomenclature, has received the name ACKR3 (atypical chemokine receptor 3). In this study, we aimed to investigate the expression of CXCR7 in leukemic cells, as well as its participation in CXCL12 response. Interesting, we clearly demonstrated that CXCR7 is highly expressed in acute lymphoid leukemic cells compared with myeloid or normal hematopoietic cells and that CXCR7 contributed to T-acute lymphoid leukemic cell migration induced by CXCL12. Moreover, we showed that the cellular location of CXCR7 varied among T-lymphoid cells and this finding may be related to their migration capacity. Finally, we hypothesized that CXCR7 potentiates CXCR4 response and may contribute to the maintenance of leukemia by initiating cell recruitment to bone marrow niches that were once occupied by normal hematopoietic stem cells.
Page 1 /9
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.