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Search Results: 1 - 10 of 1072 matches for " Bhattacharyya Nirmal "
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Guided fine needle aspiration cytology of retroperitoneal masses - Our experience
Gangopadhyay Mimi,Bhattacharyya Nirmal,Ray Sailes,Chakrabarty Subrata
Journal of Cytology , 2011,
Abstract: Background : Early pathological classification of retroperitoneal masses is important for pin-point diagnosis and timely management. Aims : This study was done to evaluate the usefulness and drawbacks of guided fine needle aspiration cytology (FNAC) of retroperitoneal masses covering a period of two years with an intention to distinguish between neoplastic and non-neoplastic lesions and to correlate with histologic findings. Materials and Methods : FNAC was done under radiological guidance in all cases using long needle fitted with disposable syringe. Appropriate staining was done and cytology was correlated with histology which was taken as the gold standard for comparison. Results : Fifty-one patients who presented with retroperitoneal masses were studied. Forty-four lesions were malignant cytologically and 7 were inflammatory (tuberculous). According to radiological and cytologic findings, we classified our cases into four groups: renal tumors, retroperitoneal lymphadenopathy, germ cell tumors, soft tissue tumors. Except for cases of non-Hodgkin lymphoma (NHL) and metastatic lesions, we had sensitivity and specificity of 100%. In NHL the sensitivity and specificity were both 50%. In cases of metastatic adenocarcinoma, the sensitivity and specificity were 84.6% and 81.8%, respectively. Conclusions : Ignoring the pitfalls, guided FNAC is still an inexpensive and reliable method of early diagnosis of retroperitoneal lesions.
Ovarian tumors in pediatric age group - A clinicopathologic study of 10 years′ cases in West Bengal, India
Bhattacharyya Nirmal,De Anuradha,Bera Pranati,Mongal Sristidhar
Indian Journal of Medical and Paediatric Oncology , 2010,
Abstract: Background and objectives: Objective in this retrospective study is to find out the incidence of different ovarian tumors of girls up to 20 years of age observed in last ten years in North Bengal Medical College and to correlate clinical and gross findings with histopathologic findings and to compare the incidence with other studies and follow-up of patients with malignant ovarian tumors. Materials and Methods: Findings were retrieved from records of different pathological reports and clinical reports. Results: Total 151 cases of ovarian tumors were received in pathology department in which 34 cases were malignant (22.6%). Amongst malignant cases, 66% are of germ-cell origin-dysgerminoma being the commonest. Strikingly we got 9 cases of malignant surface epithelial tumor. As per follow-up records most of the dysgerminoma came in stage IA and recovered fully following chemotherapy and radiotherapy. Amongst other malignant tumors, few lost the follow-up management and others expired due to metastasis. Conclusions: Patients from hilly areas of North Bengal and low socio-economic status led to lower detection rate of ovarian tumors in early stage which are absolutely necessary for proper guidelines of management to reduce mortality.
Clinicopathologic study of pelvic lesions managed by surgeons in a medical college in Kolkata in the last 2 years
Bhattacharyya Nirmal,Mallick Mamata,Roy Himansu,Das Mrinal
Indian Journal of Pathology and Microbiology , 2008,
Abstract: The pelvic cavity is a basin-like space in the lowermost part of the abdomen where various neoplastic and non neoplastic lesions can occur involving its contents. When the nature of lesions are not clearly gynecological, patients are managed by surgeons. Our study aims to asses the clinicopathologic analysis of neoplastic lesions of the pelvic cavity managed by surgeons particularly over a period of 2 years. Out of 162 total lesions, 102 cases were non neoplastic, such as appendicular lump, Tubo-ovarian (TO) mass, hematoma and 60 cases were neoplastic. Among the 60 cases of neoplastic lesions, 40 cases were benign comprised of twisted ovarian cyst, broad-ligament fibroid, and neurofibroma and 20 cases were malignant comprised of colorectal carcinoma, ovarian carcinoma, liposarcoma, Primitive nurectodermal tumor (PNET), seminoma, and lymphnode metastasis. The lesions in such closed, difficult to approach areas throws clinicians into a diagnostic dilemma during both the preoperative and intraoperative period. Even pathologists cannot ascertain some diagnosis without the help of immunohistochemistry. So, to adopt early and concise management protocol, there should be more such studies in different institutions that are currently lacking in world literature.
Banter: An Alternative Strategy in Creating a Learning Community  [PDF]
Sumita Bhattacharyya
Creative Education (CE) , 2013, DOI: 10.4236/ce.2013.43030
Abstract: In this qualitative study we investigated the role of bantering in creating a learning community for science education. The curriculum was centered on a technology-integrated Project Based Approach (PBA). We examined the pattern of in-service teachers’ interaction with such a learning environment and perceptions of their future instructional practices that result from collaborative reflection on the use of Banter throughout the semester. The findings suggest that exposure to bantering interaction not only helped the in-service teachers to make decisions about the scientific issues they will face in the future but also helped to construct a more inquiry based understanding of the issues in science teaching. Methodological limits and possibilities were explored through the use of data analysis software such as Inspiration and NVivo.


The Unexplored Role of Probiotics on the Parasitic Pathogens  [PDF]
Bratati Mukhopadhyay, Nirmal Kumar Ganguly
Food and Nutrition Sciences (FNS) , 2014, DOI: 10.4236/fns.2014.522230
Abstract: The beneficial bacteria coined as probiotics are used as therapeutics to the host and evidences are there to demonstrate to treat bacterial and viral respiratory infections, gastrointestinal diseases, eczema, inflammation, H. pylori infection, irritable bowel syndrome and allergic symptoms etc. In recent past, probiotics has been reported for the control of intestinal parasite infections as well as few non-gut infections spread among human and veterinary animals. Animal models and in vitro culture systems have been studied regarding cellular interactions between probiotics and pathogens or relevant host cells, though the underlying molecular mechanisms mediating the beneficial effects have not yet fully discovered. Hence, more evidence based studies are warranted to correlate whether probiotics through multiple mechanisms might indeed provide a strain-specific protection against parasites to use it as therapeutics. This article has described the effect of probiotics in some of the intestinal as well as non-gut parasites and suggested the scope of exploring the benefit for protozoan parasite Leishmania, as India is planning for the elimination of the disease.
RNTCP and tuberculosis control - High time to act
Jain Nirmal
Lung India , 2010,
Abstract:
Experimental evidences in support of the biological effects and physical basis of homeopathic potencies
Nirmal Sukul
International Journal of High Dilution Research , 2012,
Abstract: Background: Homeopathic potencies 12 cH and above cross the Avogadro number and, for this, do not contain any original drug molecules. Two major problems involved in the scientific study of potencies are (1) understanding the physical basis of potencies and (2) demonstrating the biological effects of potencies. The present study aims to address these questions. Methods and Results: In course of our experimental studies spanned over more than 30 years we have demonstrated significant effects of homeopathic potencies on man, animals and plants. We have also showed that potencies could be differentiated through their electronic spectra, and this difference in spectra can be attributed to the electron transfer interaction. In a molecular complex, electron of one molecule absorbs a quantum of visible radiation and is excited, not to a higher energy level of this molecule, but to one of the vacant high energy levels of the neighboring molecules. This process is known as electron or charge transfer interaction. This has been demonstrated in Iodine in two different solvents of CCl4 and aqueous ethanol (Sukul N C, Environ Ecol 17,866-872, 1999). We have further demonstrated that the effect of a homeopathic potency can be transmitted from one part of a plant to another, and also from one plant to another through water. I am presenting here a few selected cases of our experimental studies. Potentized Nux vomica significantly reduced ethanol consumption in rats by 73.7%and ethanol-induced sleep time in albino mice by 44.4%. Causticum 30 C and Rhus tox 30 C produced anti-inflamatory and anti-nocicptive effect on adjuvant arthritis in albino rats. Potentized homeopathic drugs reduced microfilaraemia by 28 to 100% and filariasis in two villages of West Bengal endemic for Bancroftian filaiasis. Potentized Cina and Thuja ameliorated trichinellosis in mice reducing larval population in muscles by 84% and 68%, respectively. Potencies of Agaricus and Nux vomica, produced excitatory effect on the isolated rat ileum. Potentized drugs altered firing rate of hypothalamic neurons in rats and cats. Nux vom 30 c and Merc cor 30c facilitated water permeability in erythrocytes of catfish in a test tube. Potencies of Merc cor and Merc iod enhanced α-amylase activity in vitro ,by 44 and 21%,respectively. Drugs ,that inhibit photosynthesis and plant growth in high doses, promote the same phenomena when applied on plants at ultra low doses. Potentized Cantharis, a homeopathic drug used for burn injuries, counter the effect of heat shock in Adhatoda vasica plants in terms of modulating
MODEL BASED TESTING CONSIDERING STEPS, LEVELS, TOOLS & STANDARDS OF SOFTWARE QUALITY
Nirmal Kumar
Journal of Global Research in Computer Science , 2011,
Abstract: This paper gives an overview to the topic of model-based testing. The model based testing process is described, and the steps available at each stage are considered. The different types of tool necessary to support the process are explained and example tools listed along with the standards they support. The position for standards in model-based testing is examined, and the new skills required by tester are discussed. Throughout research on model-based testing in the last 5-10 years has verified the probability of this approach. It has been shown that it can be cost-effective, and has developed a variety of test generation strategies and model coverage criteria. Some commercial tools have started to emerge, from the USA (T-Vec, Reactive Systems, I-logix), and also from Europe (Conformiq, Leirios Technologies, Telelogic), as well as a wide variety of academic and research tools [BFS05]. The discussion in this paper is limited to functional testing, because model-based testing is less mature in other areas. Finally, means of determining the appropriateness of projects for model-based testing are considered. In this paper following factors are analyzed: Model Based Testing, Steps, Levels, Methods & tools that affect MBT. Keywords: model-based testing, Design, UML, Generation Criteria
MODEL BASED TESTING CONSIDERING STEPS, LEVELS, TOOLS & STANDARDS OF SOFTWARE QUALITY
Nirmal Kumar
Journal of Global Research in Computer Science , 2011,
Abstract: This paper gives an overview to the topic of model-based testing. The model based testing process is described, and the steps available at each stage are considered. The different types of tool necessary to support the process are explained and example tools listed along with the standards they support. The position for standards in model-based testing is examined, and the new skills required by tester are discussed. Throughout research on model-based testing in the last 5-10 years has verified the probability of this approach. It has been shown that it can be cost-effective, and has developed a variety of test generation strategies and model coverage criteria. Some commercial tools have started to emerge, from the USA (T-Vec, Reactive Systems, I-logix), and also from Europe (Conformiq, Leirios Technologies, Telelogic), as well as a wide variety of academic and research tools [BFS05]. The discussion in this paper is limited to functional testing, because model-based testing is less mature in other areas. Finally, means of determining the appropriateness of projects for model-based testing are considered. In this paper following factors are analyzed: Model Based Testing, Steps, Levels, Methods & tools that affect MBT.
Staging Unincorporated Power: Richard Harding Davis and the Critique of Imperial News
Nirmal Trivedi
Journal of Transnational American Studies , 2011,
Abstract: This essay contextualizes the work of war correspondent Richard Harding Davis within an evolving “imperial news apparatus” that would culminate in his reporting of the Spanish-American War. Critics have conventionally framed Davis squarely within the imperial cause, associating him with his admirer Roosevelt and naval admiral Alfred T. Mahan. Contrary to readings of Davis as an apologist for US imperialism, Trivedi contends that Davis understood how US imperial power relied on an information apparatus to communicate to an increasingly media-conscious American public through culture, that is, via familiar narratives, symbols, and objects—what Trivedi calls “imperial news.” The essay follows Davis’s development from his fictional representation of the new war correspondent in “The Reporter Who Made Himself King” to his own war correspondence before and after the Spanish-American War as collected in the memoirs A Year from a Reporter’s Notebook (1897), Cuba in War Time (1897), and Notes of a War Correspondent (1912). Davis’s war correspondence and fictional work effectively stage US imperialism as “unincorporated power”: that is, as power reliant on a developing news-making apparatus that deploys particular discursive strategies to validate its political claims. This staging critiques strategies of US imperial sovereignty—specifically its “privatization of knowledge” and its promotion of the war correspondent as nothing more than a spectator and purveyor of massacres.
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