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Standarization and optimization of micromeretic properties of nimesulide for processing into a tablet dosage form by crystalo-co-agglomeration technology
Bhattacharyya Subhra,Bhattacharyya Indrani,Patro Niranjan
Asian Journal of Pharmaceutics , 2010,
Abstract: The present study was undertaken to prepare direct compressible tablets of nimesulide by altering its physical properties with the help of the method crystallo-co-agglomeration technology. Nimesulide is a widely used nonsteroidal anti-inflammatory drugs type of drug and is very useful in the treatment of arthritis. Because of its poor flowability character, tablets of nimesulide cannot be prepared by direct compression. An attempt has been taken to improve the tableting property by altering the micromeretic properties, like flow rate, Carr index, Hausner ratio and angle of repose. Conformation of improvement of compressibility and other processing problems was studied by Heckel analysis and Kawakita constant using a hydraulic press under a pressure of 0.5, 1, 2 and 4 tonnes for 10 s. The tablets were prepared by direct compression of nimesulide agglomerates using two different types of polymers, polyethelene glycol (PEG6000) and ethyl cellulose (EC) in different ratios (50, 100 and 200 mg). The drug release shows different patterns for the various percentages of PEG and EC.
Health Status and Access to Health Services in Indian Slums  [PDF]
Indrani Gupta, Pradeep Guin
Health (Health) , 2015, DOI: 10.4236/health.2015.72029
Abstract: This paper analyzes the state of health and access to health services among the urban poor in India. Analysis is based on data from a primary survey conducted among 2000 households, covering 10,929 individuals from four cities of India. Summary statistics and regressions (using STATA) are used for data analysis. Results show lack of government facilities and services, a very high preference for private health facilities, high expenses especially in private but also in public facilities, and a perception that private facilities are offering high quality services as important concerns. An econometric analysis of the determinants of acute illness indicates the insufficiency of basic amenities like sanitation, garbage disposal and potable water. Together with the lack of availability of government health facilities in the vicinity, these results indicate continued vulnerability of the urban poor, and the need for urgent government action.
Banter: An Alternative Strategy in Creating a Learning Community  [PDF]
Sumita Bhattacharyya
Creative Education (CE) , 2013, DOI: 10.4236/ce.2013.43030
Abstract: In this qualitative study we investigated the role of bantering in creating a learning community for science education. The curriculum was centered on a technology-integrated Project Based Approach (PBA). We examined the pattern of in-service teachers’ interaction with such a learning environment and perceptions of their future instructional practices that result from collaborative reflection on the use of Banter throughout the semester. The findings suggest that exposure to bantering interaction not only helped the in-service teachers to make decisions about the scientific issues they will face in the future but also helped to construct a more inquiry based understanding of the issues in science teaching. Methodological limits and possibilities were explored through the use of data analysis software such as Inspiration and NVivo.


A Comprehensive Study on the 2012 Dengue Fever Outbreak in Kolkata, India
Bhaswati Bandyopadhyay,Indrani Bhattacharyya,Srima Adhikary,Jayshree Konar,Nidhi Dawar,Jayeeta Sarkar,Saiantani Mondal,Mayank Singh Chauhan,Nemai Bhattacharya,Anita Chakravarty,Asit Biswas,Bibhuti Saha
ISRN Virology , 2013, DOI: 10.5402/2013/207580
Abstract: Background. Dengue viruses (DV) belong to the family Flaviviridae, with four serotypes referred to as DV-1, DV-2, DV-3, and DV-4. A large-scale outbreak of dengue fever occurred in 2012 involving several districts of West Bengal. Objective. To present a comprehensive picture of the dengue fever outbreak in 2012 and to identify the prevailing serotypes. Materials and Methods. Serum samples were collected from suspected dengue fever cases. Samples from fever cases <5 days duration were tested for dengue NS1 antigen employing Pan Bio (Australia) NS1 ELISA kit. Serum samples of ≥5 days fever were tested for dengue-specific IgM by MAC ELISA test kit prepared by the National Institute of Virology Pune, India. Serotyping of dengue samples was done by dengue-specific reverse transcriptase polymerase chain reaction (RT-PCR). Results. The number of dengue cases in 2012 clearly outnumbered the dengue cases in 2010 and 2011. The majority of the cases were in the age group 11–30 years with a male preponderance. Outbreak occurred during the months of Aug.–Nov. indicating increased vector transmission in the monsoon and postmonsoon periods. The prevailing serotypes in this outbreak were Den1, Den3, and Den4. 1. Introduction Dengue viruses (DV) belong to the family Flaviviridae, and there are four serotypes of the virus referred to as DV-1, DV-2, DV-3, and DV-4 [1]. DV is a positive-stranded encapsulated RNA virus and is composed of three structural protein genes, which encode the nucleocapsid or core (C) protein, a membrane-associated (M) protein, an enveloped (E) glycoprotein, and seven nonstructural (NS) proteins. It is transmitted mainly by Aedes aegypti mosquito and also by Ae. albopictus. All four serotypes can cause the full spectrum of disease from a subclinical infection to a mild self-limiting disease, the dengue fever (DF), a severe disease that may be fatal, and the dengue haemorrhagic fever/dengue shock syndrome (DHF/DSS). Dengue is the most common and widespread arboviral infection in the world today. It is an increasingly prevalent tropical arbovirus infection with significant morbidity and mortality [1]. dengue infection has been known to be endemic in India for over two centuries as a benign and self-limited disease. In recent years, the disease has changed its course manifesting in the severe form as DHF and with increasing frequency of outbreaks [2]. dengue infection in a previously nonimmune host produces a primary response of antibodies characterized by a slow and low-titer antibody response. IgM antibody is the first immunoglobulin isotype to
Status Of Women From Pre-vedic To Contemporary India- Is It A Ray Towards Empowerment Or Story Of Coercion?
Indrani Basu
Golden Research Thoughts , 2013, DOI: 10.9780/22315063
Abstract: The analysis of women's activities within family is still sat somewhat on the periphery of the discipline of economics. Though some discussion has made, but has not been found satisfactory for dealing with the issues in developing economics. Marxist-feminist has moved towards accepting the importance of looking inside the family. Women of contemporary India are both family provider and bread winner. Therefore a details discussion on their status in society is very much needed issue. However, neither the family nor its reproductive behaviour is static in any society. This is also applicable for market. Their nature changes radically during the process of social evolution. Each society constructs a set of social, cultural, economical, political and legal processes that is crucial for supporting its institution, like family and market.
Entanglement - A Queer In The World Of Quantum : Some Perspectives
Indrani Chattopadhyay
Physics , 2008,
Abstract: The work is intended to represent some interesting and apparently peculiar features of entangled system in both pure as well as mixed states level. In the pure state level, we are largely concerned about the existence and characteristics of bipartite incomparable pair of states. We have found some schemes for local transformation of one pure bipartite state to another, incomparable in nature, by exploiting free unpreserved entanglement. Also, we observed that different incomparable pair of states in $3\times 3$ may co-operate with each other to cross the barrier of incomparability. Our next goal was to probe critically the roots of the existence of incomparable states. We have succeeded in connecting incomparability with some famous no-go theorems of quantum mechanics. We have established it with no-flipping principle, general anti-unitary operators and lastly with inner product preserving operations. Thus we are able to pose incomparability as a good detector of some non-physical operations. In the next part, we provide a new class of multipartite bound entanglement in mixed state level. The class of states are activable bound entangled. There are exactly four orthogonal activable bound entangled states in any even number of qubit system. They have some interesting features like Bell correlation, permutation symmetry, local Pauli connection, non-compatibility, etc. Apart from those properties, the class of bound entangled states have the remarkable feature of local indistinguishability in quantum systems.
Antiferromagnetic systems with spin gap: exact results
Indrani Bose
Physics , 1996,
Abstract: We describe some antiferromagnetic systems which exhibit spin gaps. We also discuss the effect of doping one such system, namely, the spin-ladders, with holes. Some model antiferromagnetic systems with spin gap are reviewed for which exact results are available. Exact results for a doped spin-ladder model are also mentioned.
Nucleosynthesis inside accretion disks and outflows formed during core collapse of massive stars
Indrani Banerjee
Physics , 2013,
Abstract: We investigate nucleosynthesis inside the gamma-ray burst (GRB) accretion disks and in the outflows launched from these disks mainly in the context of Type II collapsars. We report the synthesis of several unusual nuclei like 31P, 39K, 43Sc, 35Cl and various isotopes of titanium, vanadium, chromium, manganese and copper in the disk. We also confirm the presence of iron-group and alpha-elements in the disk, as shown by previous authors. Much of these heavy elements thus synthesized are ejected from the disk and survive in the outflows. While emission lines of several of these elements have been observed in the X-ray afterglows of GRBs by BeppoSAX, Chandra, XMM-Newton etc., Swift seems to have not found these lines yet.
The Physical Basis of Integrable Spin Models
Indrani Bose
Physics , 2002,
Abstract: Integrable models are often constructed with real systems in mind. The exact solvability of the models leads to results which are unambiguous and provide the correct physical picture. In this review, we discuss the physical basis of some integrable spin models and their relevance in the study of real systems. The emphasis in the review is on physical understanding rather than on the mathematical aspects of integrability.
Low-dimensional quantum spin systems
Indrani Bose
Physics , 2000,
Abstract: Low-dimensional quantum spin systems are interacting many body systems for which several rigorous results are known. Powerful techniques like the Bethe Ansatz provide exact knowledge of the ground state energy and low-lying excitation spectrum. A large number of compounds exists which can effectively be described as low-dimensional spin systems. Thus many of the rigorous results are also of experimental relevance. In this Lecture Note, an introduction is given to quantum spin systems and the rigorous results known for such systems. Some general theorems and exactly-solvable models are discussed. An elementary introduction to the Bethe Ansatz technique is given.
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