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Search Results: 1 - 10 of 328 matches for " Bhanu Mehra "
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Rapid Tests versus ELISA for Screening of HIV Infection: Our Experience from a Voluntary Counselling and Testing Facility of a Tertiary Care Centre in North India
Bhanu Mehra,Sonali Bhattar,Preena Bhalla,Deepti Rawat
ISRN AIDS , 2014, DOI: 10.1155/2014/296840
Abstract: Early and accurate diagnosis of human immunodeficiency virus (HIV) infection is essential for timely identification of patients needing antiretroviral therapy and for instituting HIV prevention strategies. The primary methodology for HIV testing has shifted from enzyme linked immunosorbent assay (ELISA) to rapid diagnostic tests (RDTs) in recent years, especially in resource limited settings. However, the diagnostic performance of RDTs is a matter of concern. In the present study the performance of an RDT being used as the initial test in serial testing based algorithm for HIV diagnosis was compared with ELISA. Seven hundred and eighty-seven sera, tested at the voluntary counselling and testing facility employing a serial testing algorithm (based on SD Bioline HIV-1/2 3.0 as the first test), were subsequently tested with Microlisa-HIV for anti-HIV antibodies. The first test missed 9 HIV reactive samples and also registered 5 false positives. The sensitivity, specificity, and negative and positive predictive values of the first test were 77.5%, 99.3%, and 98.8% and 86.1%, respectively, taking ELISA as the standard test. Our study highlights that RDTs fare poorly compared to ELISA as screening assays and that reactive results by RDTs need to be confirmed by western blot for a positive serodiagnosis of HIV infection. 1. Introduction Approximately 35.3 million people across the world are infected with human immunodeficiency virus (HIV) [1]. Early and accurate knowledge of HIV serostatus of an individual is the cornerstone of HIV prevention and therapeutic intervention. In addition to allowing timely initiation of antiretroviral therapy of the HIV infection, early diagnosis also provides an opportunity to limit the spread of HIV from the infected individuals to the naive population. Detection of anti-HIV antibodies as a marker of HIV exposure is the most widely used approach for serodiagnosis of this infection. Enzyme linked immunosorbent assay (ELISA) has been a preferred screening procedure in this regard [2]. However the labour intensive and time consuming format of the assay as well as the requirement of instrumentation and technical expertise has resulted in a shift from an ELISA based approach to rapid diagnostic tests (RDTs), particularly in resource constrained settings. While some studies have reported the performance of RDTs and ELISA to be comparable [3], results from others have raised concerns regarding sensitivity and specificity of the rapid assays [4–6]. With regard to HIV testing, two testing algorithms are commonly described: parallel and
The Role of Library and Information Science Education in the Development of Community Health Information Services for People Living with HIV/AIDS: Perspectives of Directors and Managers of Public Libraries  [PDF]
Bharat Mehra, Adrienne Dessel
World Journal of AIDS (WJA) , 2011, DOI: 10.4236/wja.2011.13012
Abstract: This article identifies the role of library and information science (LIS) education in the development of community health information services for people living with HIV/AIDS (PLWHA). Preliminary findings are presented from semi- structured qualitative interviews that were conducted with eleven directors and managers of local branches in the Knox County Public Library (KCPL) System that is located in the East Tennessee region in the United States. Select feedback reported by research participants is summarized in the article about strategies in LIS education that can help local public librarians and others in their efforts to become more responsive information providers to PLWHA. Research findings help better understand the issues and concerns regarding the development of digital and non-digital health information services for PLWHA in local public library institutions.
Measurement of Radioactivity of 238U, 226Ra, 232Th and 40K in Soil of Different Geological Origins in Northern India  [PDF]
Rohit Mehra, Manmohan Singh
Journal of Environmental Protection (JEP) , 2011, DOI: 10.4236/jep.2011.27110
Abstract: Radioactivity of the nuclides 238U, 226Ra, 232Th and 40K was measured in soil by γ-ray spectrometry using HPGe detector. A criterion was set in order to analyse soil samples from plain, semi-hilly and hilly areas in northern India. More than three γ-ray energy peaks were used for the determination of 226Ra and 232Th activity concentrations to obtain more accurate results. Some of these peaks have interfering energies, which was caused by the limited resolution of the detector, but they were resolved theoretically and used in the analysis because of their significance in reducing the random error to its minimum level. Relationships between the measured radionuclides have been discussed elaborately. Radionuclides 238U and 226Ra were found in disequilibrium with ratio of specific activities 238U/, 226Ra) less than unity for most of the samples. In some cases this disequilibrium may be significant enough to modify the γ-ray dose factors.
Gap Functions and Error Bounds for Set-Valued Vector Quasi Variational Inequality Problems  [PDF]
Rachana Gupta, Aparna Mehra
Applied Mathematics (AM) , 2017, DOI: 10.4236/am.2017.812135
One of the classical approaches in the analysis of a variational inequality problem is to transform it into an equivalent optimization problem via the notion of gap function. The gap functions are useful tools in deriving the error bounds which provide an estimated distance between a specific point and the exact solution of variational inequality problem. In this paper, we follow a similar approach for set-valued vector quasi variational inequality problems and define the gap functions based on scalarization scheme as well as the one with no scalar parameter. The error bounds results are obtained under fixed point symmetric and locally α-Holder assumptions on the set-valued map describing the domain of solution space of a set-valued vector quasi variational inequality problem.
Patient satisfaction
Prakash Bhanu
Journal of Cutaneous and Aesthetic Surgery , 2010,
Abstract: Patient satisfaction is an important and commonly used indicator for measuring the quality in health care. Patient satisfaction affects clinical outcomes, patient retention, and medical malpractice claims. It affects the timely, efficient, and patient-centered delivery of quality health care. Patient satisfaction is thus a proxy but a very effective indicator to measure the success of doctors and hospitals. This article discusses as to how to ensure patient satisfaction in dermatological practice.
Puccinia jabalpurensis sp. nov. on exotic weed Lagascea mollis from India
Indian Phytopathology , 2011,
Abstract: A new species of rust fungus, Puccinia jabalpurensis collected from Lagascea mollis (Asteraceae), from Central part of India is described and illustrated. This new species of Puccinia is characterized by the presence of unique combination of features viz. compact and stromatic telia, various types of teleutospores (mostly two celled, one celled mesospore often present, three celled spores very rare), usually persistent, smooth, cylindrical to flexuous and longer teleutospore pedicel.
Biogenic amines and tumor-vascular interaction in melanomas
Bhanu Iyengar
Journal of Solid Tumors , 2011, DOI: 10.5430/jst.v1n2p44
Abstract: Background In nodular melanomas in vertical growth phase, tumor-vascular complexes (TVC), with perivascular mantle zone (PMZ) of 5 to 6 layers (L1-L5) of tumor cells are formed around angiogenic vessels at the tumor-stroma interphase, showing organized neural differentiaton. The present study explores the sequence of biogenic amines positivity in relation to angiogenesis, utilizing the TVC as a 3D model. Methods The sequence of positivity for Nestin (Nes), GFAP, indoleamines: serotonin (SER)/melatonin (MLT), catecholamines: dopamine (DA)/noradrenalin (NA), pigment (Pig); dopa oxidase (DO); and related mitosis in layers of the PMZ (L1-L5) was assessed in 897 developing TVCs using 5 μm serial paraffin and frozen sections. Statistical Analysis: ANOVA: Kruskal-Wallis One Way Analysis of Variance; All Pairwise Multiple Comparison Procedures (Tukey Test). Results Nes, GFAP appear in L1/L2, next indoleamines (serotonin/melatonin) in L2/L3 associated with mitosis. DA is positive in L3/L4 coinciding with DO which peaks in L4 with NA, Pig appears in L4/L5. Mitosis in L2/L3 is associated with indoleamine positive cells which remain in L2/L3, with catecholamine positive cells moving into L4/L5 thus establishing a polarity. Conclusion Thus, the angiogenic vessel confers polarity and an embryonal microenviron
A Companion to Qualitative Research by Ewe Flick, Ernst von Kardoff and Ines Steinke. 2004
Bhanu Timseena
Nepalese Journal of Qualitative Research Methods , 2007, DOI: 10.3126/njqrm.v1i0.1977
Abstract: doi: 10.3126/njqrm.v1i0.1977 Nepalese Journal of Qualitative Research Methods Vol.1 2007 pp.68-71
Application of Qualitative and Quantitative Research Methods in Development Domain: Sharing of Some Anthropological Experiences from Rural Development Projects
Bhanu Timseena
Nepalese Journal of Qualitative Research Methods , 2007, DOI: 10.3126/njqrm.v1i0.1973
Abstract: doi: 10.3126/njqrm.v1i0.1973 Keywords: Development Domain; Rural Development Nepalese Journal of Qualitative Research Methods Vol.1 2007 pp.51-63
Dynamical net charge fluctuations at RHIC energies in STAR
Bhanu Sharma
Physics , 2015,
Abstract: We present preliminary results from the study of dynamical net-charge fluctuations measured in Au+Au collisions at $\sqrt{s_{NN}}$ = 39 GeV to 7.7 GeV and compare with the published results at higher collision energies. We also present the centrality dependence of the dynamical net-charge fluctuations.
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