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Search Results: 1 - 10 of 189806 matches for " Bhagya G. Thenuwara "
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Peritoneal Dialysis in Dengue Shock Syndrome May Be Detrimental
Chulananda D. A. Goonasekera,Bhagya G. Thenuwara,Ranjith P. V. Kumarasiri
Journal of Tropical Medicine , 2012, DOI: 10.1155/2012/917947
Abstract: Dengue shock syndrome is the most severe form of Dengue that can be fatal. Nonresponders to standard therapy need intensive care. This paper outlines the clinical features, complications, and outcomes of Dengue Shock Syndrome not responding to standard therapies and needing supportive care in a tertiary referral intensive care unit of a developing country. Nearly one-third die within 3 days of admission to ICU. Peritoneal dialysis predicts the worst outcomes. 1. Introduction Dengue is an important arthropod-borne viral disease of humans [1]. Its presentation varies from a mild viral syndrome to hemorrhagic fever and severe shock. Its severe forms (hemorrhagic fever and shock syndrome) may lead to multiorgan involvement and death. Dengue Shock Syndrome (DSS) is characterized by a massive increase in systemic capillary permeability with consequent hypovolemia [2]. The mortality rate in Dengue Shock Syndrome ranges from 6 to 30 percent, most commonly reported in children. Fluid resuscitation is critical with added support for failing organs [3]. In the recent past, Sri Lanka has experienced a surge of the disease reaching epidemic proportions associated with a probable change in the virus strain to a more virulent form [4, 5]. In this context we have also noted a rise in the number of cases with severe forms of the disease needing intensive care. The Peradeniya ICU is a tertiary referral centre and it attracts a large number of above patients with Dengue Shock Syndrome in the region who do not respond to standard therapy with intravenous fluids, antibiotics, and supportive care including inotropes. 2. Methods We collected demographic data of all patients referred for intensive care between January 2009 and June 2010 (18 months) and analyzed their outcomes in relation to the complications of DSS that ensued during their ICU stay and the therapies given. The diagnosis of Dengue has been established upon clinical grounds (WHO guidelines 2009) and treated accordingly by the referring physicians before admission to the ICU. On admission to ICU, all have had fever, vomiting 78%, abdominal pain 21%, cough 5%, and body ache among 3% of cases. Eleven patients have had serological tests and Dengue IgM was found to be positive amongst 72% and IgG in 50% of the tested. They all have had intravenous fluid therapies and antibiotics. During the course of therapy in ICU, 43.6% of cases received fresh frozen plasma, 21.8% cryoprecipitate, 32.7% blood, and 56.4% platelet transfusions. Furthermore, 36.4% of cases were mechanically ventilated for multiple reasons such as
Study Of Transmission Characteristics Of 2x2 Mimo System for OFDM Multiplexing and Bpsk Modulation With ZF Equalizer And MMSE Receivers
Bhagya. R,,A. G. Ananth
International Journal of Soft Computing & Engineering , 2012,
Abstract: A detailed analysis of 2×2 MIMO (Multiple Input Multiple Output) combined with OFDM (Orthogonal Frequency Division Multiplexing) transmission system and BPSK modulation has been carried out. The BER performance of the system has been determined for Additive white Gaussian Noise (AWGN) presuming Flat fading Rayleigh channel. On the receiver side linear equalization techniques such as Zero Force Equalizer (ZF) and Minimum Mean Square Error (MMSE) detectors were employed for studying the BER performance. The simulation results show that for BER of ~10-4, the SNR required are ~34 dB for ZF equalizer and ~31dB for MMSE equalizer. The simulation results indicate that the MMSE equalizer shows better performance ~3 dB over the ZF equalizer. Further comparison of the 2X2 MIMO performance of OFDM with STBC multiplexing indicates comparable BER performances. The simulation results are presented and discussed in the paper.
Demographics and Asset Markets: A Survey of the Literature  [PDF]
Wasanthi Thenuwara, Mahinda Siriwardana, Nam Hoang
Theoretical Economics Letters (TEL) , 2017, DOI: 10.4236/tel.2017.74057
Abstract: This paper surveys the theoretical and empirical literature examining the effects of population age structure on financial asset prices, including critical reviews of the methodologies used and an evaluation of contradictory results. The survey focuses on the effects of the Baby Boom generation on asset prices, and in particular, the question of the asset meltdown hypothesis (AMH). The existing literature reveals that an asset meltdown may never eventuate nevertheless it remains plausible that ageing of the Baby Boomers will have a significant negative impact on asset prices. The previous studies were based on where the proportion of the old age population is relatively low. With the first Baby Boomers reaching 65 years of age in 2011 this proportion is projected to increase substantially and hence the effect is reinforced. Thus new research is needed to address the unresolved issues given that population ageing has serious policy issues in the developed economies.
Transmission characteristics of 4x4 MIMO system with OFDM multiplexing and Markov Chain Monte Carlo Receiver
R Bhagya,Pramodini D V,A G Ananth
International Journal of Soft Computing & Engineering , 2011,
Abstract: A detailed analysis of the performance of 4×4Multiple Input Multiple Output (MIMO) antenna system hasbeen carried out using Orthogonal Frequency DivisionMultiplexing (OFDM) techniques. The transmissioncharacteristics are determined for BPSK and 16-QAM digitalmodulation. Additive White Gaussian Noise (AWGN) has beenused for the channel. On the receiver side, Markov Chain MonteCarlo (MCMC) receiver techniques have been employed forcomputing the BER performance. The simulation results showthat, for BER of ~10-4, the SNR achieved are significantlyhigher. The results indicate for BPSK modulation the SNR ~ 9dB, and for 16-QAM modulation the SNR ~13 dB. The MIMOOFDMmultiplexing scheme show a overall improvement of ~4.0 dB for BER values of 10-4 between BPSK and 16-QAMmodulation. A comparison of the performance of presentMIMO-OFDM multiplexing system with MIMO-CDMA systemand common MCMC receiver indicates that, the MIMO-OFDMMultiplexing exhibits a better BER performance for 16-QAMdigital modulation. The simulations results are presented anddiscussed in the paper.
Effect of Sodium Valproate pretreatment on Haloperidol induced catalepsy in rats
Sattigeri Bhagya Manoj,Balsara J J
Pravara Medical Review , 2009,
Abstract: Sodium valproate a broad spectrum antiepileptic, elevates the brain GABA levels. Studies have suggested a regulatory role of GABA on Dopaminergic neurons. Behavioural studies in animals have provided additional interaction between GABAergic and DAergic systems. Hypofuntioning of nigrostriatal DAergic system in rats is responsible for induction of catalepsy. Haloperidol induces catalepsy in rats by blocking post synaptic striatal D2DA receptors. Hence the study was taken up to evaluate the effect of sodium valproate pretreatment on Haloperidol induced catalepsy. Sodium valproate 100 to 400 mg/Kg significantly increased the cataleptic effect of Haloperidol at both 1 and 2 hour testing time intervals.
Prevalence and Pattern of Consanguineous Marriages Among Different Communities in Mangalore
Bhagya Bhaskar,Sucharitha Suresh,Ramakrishna Avadhani
Online Journal of Health & Allied Sciences , 2013,
Abstract: Introduction: Consanguineous marriages are a common practice in the Middle East, Asian and African populations. Many studies have stated an association between first cousin marriages and the incidence of autosomal recessive diseases and congenital malformations. High frequency of consanguinity is reported by researchers among South India. The objectives of this study were to determine the prevalence and type of consanguineous marriages among the different communities of Mangalore. Methods: This study was conducted on 1164 married women in Mangalore to investigate the prevalence and type of consanguineous marriages. All the women were interviewed personally using a structured questionnaire. Family pedigree was constructed to study the type of consanguineous marriages. Data analysis was done by SPSS Win 13.0. Results: A low percentage of consanguinity (6.53%) was observed with a mean inbreeding coefficient of 0.0339. Frequency of consanguinity between religions was highly significant. Of these the most frequent were first cousin marriages (43.42%). Within Hindu religion the highest rate of consanguinity was among the Billavas (47.62%) of which the most frequent were distant relative marriages (75%) followed by second cousin marriages (57.14%). There was no significant difference in the frequency distribution of the types of consanguinity between the religions and also between the different groups among Hindus. Conclusion: The frequency of consanguinity was found to be low in Mangalore. The findings contradict with the earlier reports of high prevalence of consanguineous marriages in South India. Increased female education, increased socio-economic status and decrease in parental decisions in marriages may be the reasons.
The amplitude of sunspot minimum as a favorable precursor for the prediction of the amplitude of the next solar maximum and the limit of the Waldmeier effect
K. B. Ramesh,N. Bhagya Lakshmi
Physics , 2011, DOI: 10.1007/s11207-011-9866-7
Abstract: The linear relationship between the maximum amplitudes (R$_{max}$) of sunspot cycles and preceding minima (R$_{min}$) is one of the precursor methods used to predict the amplitude of the upcoming solar cycle. In the recent past this method has been subjected to severe criticism. In this communication we show that this simple method is reliable and can profitably be used for prediction purposes. With the 13-month smoothed R$_{min}$ of 1.8 at the beginning, it is predicted that the R$_{max}$ of the ongoing cycle will be around 85$\pm$17, suggesting that Cycle 24 may be of moderate strength. Based on a second order polynomial dependence between the rise time (T$_R$) and R$_{max}$, it is predicted that Cycle 24 will reach its smoothed maximum amplitude during the third quarter of the year 2013. An important finding of this paper is that the rise time cycle amplitude relation reaches a minimum at about 3 to 3.5 years corresponding to a cycle amplitude of about 160. The Waldmeier effect breaks at this point and T$_{R}$ increases further with increase in R$_{max}$. This feature, we believe, may put a constraint on the flux transport dynamo models and lead to more accurate physical principles based predictions.
Genetic Variability and Path Analysis Studies in Hybrid Maize (Zea mays L.)  [PDF]
Mohammad Quamrul Islam Matin, Md. Shalim Uddin, Md. Motiar Rohman, Mohammad Amiruzzaman, Abul Kalam Azad, Bhagya Rani Banik
American Journal of Plant Sciences (AJPS) , 2017, DOI: 10.4236/ajps.2017.812209
Abstract: The present study was carried out to access correlation coefficient, path analysis and genetic variability among twenty one locally developed maize hybrids for ten characters. Positive and significant genotypic, phenotypic correlation coefficient were recorded for yield with anthesis silking interval (rg = 1.00**, rp = 0.96**), cob diameter (rg = 0.99** and rp = 0.95**) and ear height (rg = 0.98** and rp = 0.94**). But days to 50% tasseling had moderate but significant positive correlation at both phenotypic and genotypic level. High genotypic coefficient of variation (GCV) was obtained from thousand seed weight, days to 50% silking, cob diameter and anthesis silking interval. The highest phenotypic coefficient of variation (PCV) was observed in thousand seed weight followed by days to 50% silking and cob diameter. The highest heritability (Hb) was observed for cob diameter (95.25) followed by days to 50% silking (94.15), days to maturity (93.85) and ear height (93.06). The characters with high GCV and higher values of heritability indicated high potential for selection. Anthesis silking interval (0.79) had the highest positive direct effect on yield followed by cob diameter (0.31), cob length (0.31) and plant height (0.04) indicating the effectiveness of direct selection. While some other characters such as days to 50% tasseling (-0.12), days to 50% silking (-1.78), ear height (-1.16), days to maturity (-0.64) exhibited indirect negative effect on yield indicating the effectiveness of indirect selection.
Serum lipid profile in prepubertal, reproductive and postmenopausal women
Bhagya V,Hemalatha N R,Veeranna H B, Banu V
International Journal of Biological and Medical Research , 2011,
Abstract: The present study was undertaken to know serum lipid profile changes in prepubertal, reproductive and postmenopausal periods in women. The fasting blood samples were collected from 120 healthy volunteers from Bangalore and total cholesterol, triglyceride, VLDL, HDL were measured by enzymatic method. LDL was calculated using Friedewald’s equation, HDL/LDL, HDL/cholesterol ratios were obtained. The results showed statistically significant increase in total cholesterol (p<0.0001) with age and also statistically significant increase in TG (p<0.0001), VLDL (p<0.0001) and LDL (p<0.0001) were observed between reproductive and postmenopausal women. HDL showed statistically significant decrease in postmenopausal women compared to reproductive age group. HDL/LDL and HDL/cholesterol ratios decreased with increasing age from reproductive to postmenopausal period (p<0.0001).Thus it can be concluded that serum lipid profile changes with possibly mediated by changing hormonal profile and sex steroids, especially estrogen which has role in lipid metabolism, thereby indirectly on coronary artery disease.
Bhagya Kodavanji,Amrutha Tripathy,Rama Swamy,P. Rajendran
International Journal of Biomedical Research , 2012, DOI: 10.7439/ijbr.v3i1.244
Abstract: Heart rate variability (HRV) is the simplest and most widely performed measure of cardiac autonomic function.Decreased HRV implicates an increased risk of arrhythmic events and an increased mortality. HRV is influenced by genetic, many environmental andbehavioral factors.The present study was an attempt to investigate the difference in the HRV between the people of same origin but born and brought up in a different social, environmental and cultural set up i.e. between the young Indian females and young Non-resident Indian (NRI) females.HRV of Sixteen Indian femalesstudents of mean age 18.41±0.5and seventeen NRI females students of mean age 18.63±0.5 were analyzed using HRV software.HRV was analyzed both by time domain and frequency domain methods during normal breathing.We observed that there was no statistical significant difference in the heart rate variability of Indians and NRIs. But the values of all the variables of time domain method and HF power andHFnu by frequency domain method during normal breathing were higher in Indians, which shows that probably Indians have a better parasympathetic tone compared to NRIs but it did not reach statistical significance level because of smaller sample size.
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