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Evaluation of the concentration of Proinflammatory/Pro Th1 Cytokines IFN- and TNF-α and anti inflammatory/Pro Th2 Cytokines IL-13 and IL-4 in breast milk and their relationship to atopic dermatitis
Moradkhani S,Mahdi M,Daneshvar H,Bazargan Harandi N
Tehran University Medical Journal , 2013,
Abstract: Background: Atopic dermatitis (AD) is one of the most common chronic, highly pruritic and inflammatory skin diseases. The exclusive influence of breastfeeding in the prevention of inflammatory diseases is a matter of debate. In this study, we aimed to determine the concentration of interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), interleukin-13 (IL-13) and interleukin-4 (IL-4) cytokines as anti Th2 or anti Th1 cytokines in breast milk and their relationship with atopic dermatitis in breastfed infants.Methods: This study carried out in Afzalipour Hospital of kerman during one year from 2010 to 2011, we selected 50 breastfed infants with AD as cases and 50 healthy infants without AD or any other allergic disease as the controls. The concentrations of pro- and anti-inflammatory cytokines were measured by ELISA in the mothers' milk. The demographic characteristics were recorded in a data collection form. Moreover, severity of the disease was determined by SCORAD index. T-test and logistic regression were used for assessment of the correlation among study variables. Results: The concentrations of IFN-γ and IL-13 were significantly higher (respectively, P=0.04, and P=0.02) in the case group. However, logistic regression revealed that only IFN-γ significantly increased the risk for atopic dermatitis (P=0.02). Concentration of TNF-α was similar in the milk from mothers belonging to the two groups.Conclusion: The results indicate that the concentrations of IFN-γ, IL-13 and IL-4 cytokines are higher in the milk of mothers whose infants have AD. However, the risk for atopic dermatitis increases by 49% by every ten-unit (in pg/mL) increase in the level of IFN-γ.
Sound Control in the Physic Lab in the Polyacryl Company and Studying the Noise Reduction by Means of Different Absorbents
Harandi
Audiology , 1999,
Abstract: Studying noise effect at the workplace has more various aspects than other factors. So it is not surprising that its adverse impact on the physical and mental state of the society has been detected to some extent. There is a significant correlation between the hearing loss and the noise pollution of the workplaces. The most important ways to lessen and control the impact of noise are: substituting the noisy equipments with ones that produce less noise, correcting noise sources and isolating the sound source. In the current study we tried to control the noise level by using various sound absorbents and measured sound level by using these different substances. The results of these measurements have reported in the current article in details.
Iranian Female Adolescent's Views on Unhealthy Snacks Consumption: A Qualitative Study
A Karimi-Shahanjarini,N Omidvar,M Bazargan,A Rashidian
Iranian Journal of Public Health , 2010,
Abstract: "nBackground: Given the increasing prevalence of obesity among Iranian adolescents and the role of consumption of un-healthy snacks in this issue, interventions that focus on factors influencing food choice are needed. This study was designed to delineate factors associated with unhealthy snack use among female Iranian adolescents."nMethods: The theory of Planned Behavior served as the framework of the study. Qualitative data were collected via nine fo-cus group discussions in two middle schools (6th to 8th grades) in a socio-economically diverse district in the city of Tehran in spring 2008. The study sample included 90 female adolescents aged 12-15 years. The sampling strategy was purposive method. Data analyzed using the "framework" method."nResults: Major factors identified by the respondents were taste, peer pressure, parental influence, easy access to unhealthy snacks, limited availability of healthy snacks, appeal of snacks, habit, high price of healthy snacks, and media advertise-ments. Nutritional value and healthiness was not one of the first priorities when buying snacks, as adolescents thought it was too early for them to worry about illness and adverse consequences of eating junk foods."nConclusions: For developing culturally sensitive evidence-based interventions that can motivate adolescents to choose healthy snacks, a broad range of factors should be taken into account.
Rapid identification of vibrio-cholerae O1 by coaglutination test using mono-specifis antibody
Bazargan SA,Fatholahzadeh B,Tabraiie B,Moazammiie N
Tehran University Medical Journal , 1996,
Abstract: In our investigation, rabbit hyper-immune serum to V.cholerae ogawa was absorbed with V.cholerae inaba whole-cells and vice versa. Applying ammonium sulphate precipitation method, mono-specific g globulins were purified and concentrated from the absorbed whole serum. These antibodies were fixed on staphylococcus cowan 1 NCTC-8325 whole-cells, using different chemical fixatives. It was observed that maximum fixation of g globulin to protein-A was achieved by 1-propanol 50% at 3 hours, which revealed through single radial immuno-diffusion techniqe. The rectal swab samples were cultured in an enrichment bile-peptons broth. After 5 hours 37°C while agitations, one drop of each sample was mixed with one drop of vibrio-cholerae bivalent mono-specific coagglutination reagent (VBCR). The results were read after 2 to 3 minutes. Finally though statistical analysis sensitivity and specificity of coagglutination test were calculated to be 95.1% and 99.2% respectively, when compared to positive & negative controls and conventional culture methods. Using VBCR, coagglutination test can be therefore considered as a simple, reliable and rapid method to detect V.cholerae O1 in the stool of patients in endemic area and less equipped laboratories
IS PEPTIC ULCER WITH HELICOBACTER INFEC TION THE CAUSE OF CHRONIC URTICARIA?
A. Farhoudi,N. Bazargan,Z. Pourpak,M. Movahedi
Iranian Journal Of Allergy, Asthma and Immunology , 2000,
Abstract: Helicobacter pylori, the most important cause of gastritis and peptic ulcer, has recently been associated with several extradigestive diseases. The aim of this study was to assess the prevalence of Helicobacter pylori infection and effects of bacterium eradication in 50 patients affected by idiopathic chronic urticaria. Helicobacter pylori was assessed by serology or biopsy and urease test or 13C urea breath test. Amoxicillin, bismuth subcitrate (Denol), metronidazole and cimetidine were given to infected patients for 2 weeks. The results of therapy were assessed by urea breath test six weeks after therapy. In response to treatment urticaria clinically regressed in 16 out of 24 patients (66.6%). Thus bacterium eradication was associated with a remission of urticaria symptoms, suggesting a possible role in the pathogenesis of this disorder.
Comparison of Five Simple Methods for DNA Extraction from Echinococcus granulosus Protoscoleces for PCR-Amplification of Ribosomal DNA
M Sharbatkhori,EB Kia,M Fasihi Harandi,N Jalalizand
Iranian Journal of Parasitology , 2009,
Abstract: "nBackground: Cystic hydatid disease is an important zoonosis, affecting humans and animals and is a significant public health and economic problem throughout the world and Iran. Since extraction of DNA from the parasite is a primary and crucial step which has a principal effect on PCR results, in the current study five simple methods for DNA extraction from protoscoleces of Echinococcus granulosus were ap-plied and compared with each other. "nMethods: After collecting hydatid cysts from an abattoir, DNA samples were extracted from two cyst isolates from sheep, two from goats and two from camels using five different methods involving the use of glass beads, mechanical grinder, freeze-thaw, boiling and crushing. For all DNA samples ex-tracted, one PCR assay based on amplifying rDNA-ITS1 region was performed and amplicons re-solved on 1.5% agarose gels. "nResults: The methods were compared regarding to DNA and PCR bands, time and cost effectiveness and laborious amount. The target DNA was successfully amplified from all samples using all methods produced an expected band size. All methods showed some advantages and disadvantages in PCR gels. The boiling method, which was the most time and cost effectiveness method, achieved the thick-est bands in the PCR following grinder, crushing, freeze-thaw and glass beads."nConclusion: Boiling and crushing methods were the most suitable methods regarding their amplicon quality, easiness, quickness and cost effectiveness.
Approximate Endpoints for Set-Valued Contractions in Metric Spaces
Hussain N,Amini-Harandi A,Cho YJ
Fixed Point Theory and Applications , 2010,
Abstract: The existence of approximate fixed points and approximate endpoints of the multivalued almost -contractions is established. We also develop quantitative estimates of the sets of approximate fixed points and approximate endpoints for multivalued almost -contractions. The proved results unify and improve recent results of Amini-Harandi (2010), M. Berinde and V. Berinde (2007), iri (2009), M. P curar and R. V. P curar (2007) and many others.
Approximate Endpoints for Set-Valued Contractions in Metric Spaces
N. Hussain,A. Amini-Harandi,Y. J. Cho
Fixed Point Theory and Applications , 2010, DOI: 10.1155/2010/614867
Abstract: The existence of approximate fixed points and approximate endpoints of the multivalued almost I-contractions is established. We also develop quantitative estimates of the sets of approximate fixed points and approximate endpoints for multivalued almost I-contractions. The proved results unify and improve recent results of Amini-Harandi (2010), M. Berinde and V. Berinde (2007), iri (2009), M. P curar and R. V. P curar (2007) and many others.
Evaluation of clinical education departments of Tehran hospitals
Farzianpoor F,Bazargan A
Tehran University Medical Journal , 1999,
Abstract: The present research evaluated the teaching of treatment hospitals of medical sciences universities in Tehran. The aim of research was a clinical diagnosis on particular nature of medical specialty, sub specialty fields promoting the quality of medical education and offering special services in teaching hospitals in comparison with standard measurements. An effective method in recognizing the strong and weak points of teaching and treatment services in teaching hospitals is choosing the Accreditation Model, that played a great role in this research. The steps to perform the model are as follows: 1) At the beginning, the medical education system criteria was mentioned according to model consisting of five parts: input-process-intermediate output-final input and outcome. The evaluation factors are: 1- Managing, treatment, teaching and research sections. 2- The theoretical, practical and experties of the faculty members. 3- The educational progress of assistants. 4- Resources, facilities, equipment and financial services in teaching of treatment center. 5- The ability to carryout teaching of treatment and clinical projects. 6- Patient satisfaction. 2) To determine if the variables are standard, the national and international documents (teaching standards of Cebec, Canada) were studied to compare the standards to the medical education system in medical hospitals. The viewpoints of board of directors in teaching hospitals were gathered. At last, the final model was devised according to the viewpoints and the final standard confirmed, 96.7% positive votes. 3) To determine the percentage role of evaluation factors, called the basis the investigation forms were filled by the managers of the hospitals according to interview and Delphi technique. The importance of each basis was investigated and confirmed in two stages in teaching hospitals in Tehran and all over Iran, according to the information. 4) According to the standards, many questions were constructed. The board of directors in teaching of treatment sections in every selected hospital determined the rank of each criteria on the hospital where they worked. After gathering the data by the investigator and determining the grades, the following linear-formula will be applied and the criteria to judge a teaching hospital on its credibility will be available. Y=a1x1+a2x2+... akxk. 5) Based on the data collected and the application of the linear formula, the hospitals in the study proved to comply with the accreditation standards. They were rated as satisfactory.
Impact of Wind Farms of DFIG Type on Power System Transient Stability  [PDF]
Libao Shi, Shiqiang Dai, Liangzhong Yao, Yixin Ni, Masoud Bazargan
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2010, DOI: 10.4236/jemaa.2010.28063
Abstract: The impact of large-scale grid-connected wind farms of Doubly-fed Induction Generator (DFIG) type on power system transient stability is elaborately discussed in this paper. In accordance with an equivalent generator/converter model, the comprehensive numerical simulations with multiple wind farms of DFIG type involved are carried out to reveal the impact of wind farm on dynamic behavior of existing interconnected power system. Different load models involving nonlinear load model and induction motor model are considered during simulations. Finally, some preliminary conclusions are summarized and discussed.
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