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Search Results: 1 - 10 of 861 matches for " Bawaskar Manish "
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Chaudhari Shilpa,Bawaskar Manish,Shirsat Ajinath
Journal of Drug Delivery and Therapeutics , 2012,
Abstract: Gastroretentive dosage forms (GRDF) enable prolonged and continuous input of the drug to the upper parts of the gastrointestinal tract and improve the bioavailability of medications those are characterized by a narrow absorption window. The aim of this study was first to develop and physico-chemically characterize an optimal single unit bilayer floating tablet for Carvedilol phosphate (CP) prepared by direct compression technology secondly use Ocimum basilicum mucilage (OBM) as a gelling, swelling and sustaining polymer in combination with HPMC and compared their drug release profile with marketed sustained release formulation for once-a-day administration of Carvedilol. Effect of OBM and its concentration on tablet properties such as hardness, friability, floating characteristics, swelling properties, tablet erosion and release patterns were evaluated. The release rate and floating characteristics could effectively be modified by varying ‘‘matrix forming swelling polymer, gas-generating agent’’ ratio. Drug release in optimized formulation was approximately 93.80% in 24 h in vitro and floating lag time around 5 min. The results showed floating tablets are a feasible approach for the sustained release (SR) preparation of CP.
Novel role of antiplatelet agents (aspirin plus clopidogrel) in an incoagulable blood of a victim of russell's viper snakebite
Bawaskar, H. S.;
Journal of Venomous Animals and Toxins including Tropical Diseases , 2006, DOI: 10.1590/S1678-91992006000100011
Abstract: snake antivenom is a specific antidote to the venom action, neutralizing the circulating venom. however, it fails to neutralize the venom fixed to target organs such as platelets, renal tubules, etc. russell's viper venom initiates rapid coagulation in a victim by activating blood platelets, factors v, x, and anticoagulant cofactors. activation of thrombin, resulting in formation of micro-thrombi, fibrinolysis, and a vicious cascade, sets in. inhibition of activated platelets by aspirin (cyclooxygenase inhibitor) and clopidogrel (adp receptor inhibitor) helps to break this vicious circle induced by russell's venom and may initiate the natural physiological clotting mechanism. they can be utilized as an adjuvant treatment.
Ectopic Autosomal Dominant Polycystic Kidney Disease (ADPKD)—An Extremely Rare Radiological Finding  [PDF]
Manish Gupta
Open Journal of Radiology (OJRad) , 2014, DOI: 10.4236/ojrad.2014.41015

ADPKD is an inherited systemic disorder that predominantly affects the kidney, but may affect other organs including liver, pancreas, brain, and arterial blood vessel. APKPD occurs worldwide affecting about 1 in 500 - 1000 people. Hypertension is the most common manifestation of ADPKD and the major contributor to renal disease progression. A definite diagnosis of ADPKD relies on image testing. Renal ultrasound is commonly used because of its cost effectiveness.

Interpretation of water quality parameters for Villages of Sanganer Tehsil, by using Multivariate Statistical analysis  [PDF]
Yashbir Singh, Manish Kumar
Journal of Water Resource and Protection (JWARP) , 2010, DOI: 10.4236/jwarp.2010.210102
Abstract: In this study, the factor analysis techniques is applied to water quality data sets obtained from the Sanganer Tehsil, Jaipur District, Rajasthan (India). The data obtained were standardized and subjected to principal components analysis (PCA) extraction to simplifying its interpretation and to define the parameters responsible for the main variability in water quality for Sanganer Tehsil in Jaipur District. The PCA analysis resulted in two factors explaining more than 94.5% of the total variation in water quality data set. The first factor indicates the variation in water quality is due to anthropogenic sources and second factor shows variation in water quality due to organic sources that are taking place in the system. Finally the results of PCA reflect a good look on the water quality monitoring and interpretation of the surface water.
A Survey on the Stability of 2-D Discrete Systems Described by Fornasini-Marchesini Second Model  [PDF]
Manish Tiwari, Amit Dhawan
Circuits and Systems (CS) , 2012, DOI: 10.4236/cs.2012.31003
Abstract: A key issue of practical importance in the two-dimensional (2-D) discrete system is stability analysis. Linear state-space models describing 2-D discrete systems have been proposed by several researchers. A popular model, called Forna- sini-Marchesini (FM) second model was proposed by Fornasini and Marchesini in 1978. The aim of this paper is to present a survey of the existing literature on the stability of FM second model.
Robust Suboptimal Guaranteed Cost Control for 2-D Discrete Systems Described by Fornasini-Marchesini First Model  [PDF]
Manish Tiwari, Amit Dhawan
Journal of Signal and Information Processing (JSIP) , 2012, DOI: 10.4236/jsip.2012.32034
Abstract: This paper considers the guaranteed cost control problem for a class of two-dimensional (2-D) uncertain discrete systems described by the Fornasini-Marchesini (FM) first model with norm-bounded uncertainties. New linear matrix inequality (LMI) based characterizations are presented for the existence of static-state feedback guaranteed cost controller which guarantees not only the asymptotic stability of closed loop systems, but also an adequate performance bound over all the admissible parameter uncertainties. Moreover, a convex optimization problem is formulated to select the suboptimal guaranteed cost controller which minimizes the upper bound of the closed-loop cost function.
Bone Transport in Tibial Gap Non-Union—A Series of 25 Cases  [PDF]
Manish Kiran, Rabi Jee
Open Journal of Orthopedics (OJO) , 2012, DOI: 10.4236/ojo.2012.24027

Gap non-union of the tibia is frequently associated with deformity, infection and shortening. Ilizarov’s method of bone transport was used in the management of twenty-five cases of gap non-union of the tibia. The mean bone gap was 6.53 cm (range 4 to 12 cm). Union was achieved in all cases within a mean period of 11.12 months. The mean time taken for union, per centimeter of bone gap was found to be 1.7 months/cm. Pin tract infection was the commonest complication, seen in 9 cases (36%). The other complications encountered were neuropraxia (n = 3) deviation of the transported bone segment (n = 7), buckling of skin at the advancing side of bone (n = 4), traumatic corticotomy (n = 3), incomplete corticotomy (n = 1), equinus deformity (n = 4), knee stiffness (n

Mono-Therapy versus Poly-Therapy: Ten Years Indian Experience on Various Seizure Disorders  [PDF]
Deepak Goel, Manish Mittal
World Journal of Neuroscience (WJNS) , 2015, DOI: 10.4236/wjns.2015.55034
Abstract: Objectives: To find out prescription patterns and seizure freedom with different mono-, duo- and poly-therapies used in various seizure disorders in Indian setting. Material and Methods: Subjects with seizures, not responding to first antiepileptic drug, were evaluated prospectively for a period of 6 months. Patients on various dual antiepileptic drugs (AEDs) prescriptions were prospectively analyzed for 1) the pattern and frequency of different duo-therapies; 2) etiological profile of patients in duo-therapy prescription; and 3) frequency of seizure freedom on various duo-therapy groups. Results: Among 2542 patients, 293 (11.5%) lost in follow-up and thus, 2249 (88.5%) were followed. 1324 (58.9%) had seizure freedom on mono-therapy, 532 (23.7%) required duo-therapy and only 45 (2%) were better controlled on poly-therapy. Among the subjects, who were on mono-therapy, Carbamazepine/Oxcarbazepine was the most commonly prescribed in 1285 (50.55%) patients as first drug followed by Valproate compound and Phenytoin. The most common duo-therapy used was combination of Valproate with Lamotregine, followed by Phenytoin and Phenobarbitone. Other mono-therapy and combinations are given in this paper. Conclusions: Duo-therapy was required and found to be effective in 23.7% of Indian patients with epilepsy. Selection of appropriate two drug combination is based on individual approach and overall clinical profile of patient.
Efficient Technique of Air-Conditioning
S. D. Suryawanshi,Tarup M. Chordia,Nikita Nenwani,Harish Bawaskar
Lecture Notes in Engineering and Computer Science , 2011,
Jayshree Ghorpade,Jitendra Parande,Madhura Kulkarni,Amit Bawaskar
Advanced Computing : an International Journal , 2012,
Abstract: The future of computation is the Graphical Processing Unit, i.e. the GPU. The promise that the graphicscards have shown in the field of image processing and accelerated rendering of 3D scenes, and thecomputational capability that these GPUs possess, they are developing into great parallel computingunits. It is quite simple to program a graphics processor to perform general parallel tasks. But afterunderstanding the various architectural aspects of the graphics processor, it can be used to performother taxing tasks as well. In this paper, we will show how CUDA can fully utilize the tremendous powerof these GPUs. CUDA is NVIDIA’s parallel computing architecture. It enables dramatic increases incomputing performance, by harnessing the power of the GPU. This paper talks about CUDA and itsarchitecture. It takes us through a comparison of CUDA C/C++ with other parallel programminglanguages like OpenCL and DirectCompute. The paper also lists out the common myths about CUDAand how the future seems to be promising for CUDA.
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