OALib Journal期刊

ISSN: 2333-9721



匹配条件: “Bandana” ,找到相关结果约30条。
Diet and lifestyle: its association with cholesterol levels among Nomad tribal populations of Rajasthan
Bandana S
International Journal of Medicine and Biomedical Research , 2012,
Abstract: Background: Dietary pattern and lifestyle may enhance the risk factors associated with cardiovascular and metabolic diseases. Aim: This study examine the dietary pattern and other lifestyle known to be associated with threatening features related to metabolic disorders. Material and Method: 1440 subjects made up of 633 males and 807 females with age group >18 years were studied from a cluster of three districts. All subjects lived in different locations of these districts of Rajasthan. Dietary patterns, physical activities related with work, habit of consuming liquor were noted while cholesterol level, blood glucose levels, blood pressure, height, weight, waist girth, and hip circumference were measured. Results: The overall prevalence rate of borderline high cholesterol level (200-239) and high cholesterol (>240) was 21.1 % and 9.4 % among select tribal populations. It was found that 71.7% were non-vegetarian and 28.3% were vegetarian out which 82.6% were males and 63.2% were females. It was observed that males (10.7%) had high cholesterol level as compared to females (8.4%). Females were slightly more at borderline high cholesterol level as compared to males. Working group (9.8%) had high level of cholesterol level as compared to non-working group (6.7%). Conclusion: Specifically meat eaters were significantly associated with high cholesterol level and liquor consumers might be prone to risk factors like high cholesterol levels as they were not significantly associated but positively correlated with high cholesterol levels. Overall consumption of mustard oil was 100% among these populations. This might be the reason for having less prevalence rate of high cholesterol level as compared to rural and urban populations.
Prevalence of diseases: a survey among ghumantoo nomad tribes of rajasthan - india
Bandana Sachdev
International Journal of Biological and Medical Research , 2011,
Abstract: Objective: To study the prevalence rate of various diseases among ghumantoo nomad tribes of Rajasthan State in India. Methods: A cross-sectional study involving 1286 ghumantoo nomadic populations in select districts of Jhunjhunu, Sikar and Churu was undertaken. Information regarding various diseases among the study population was obtained through questionnaires. Results: The major diseases that were prevalent ; Allergies, Cough, Asthma, Gastric pain, leucorrhea, Body pain, Dental , Eye and Ear problem , Constipation, Hypertension, and Blood sugar. Conclusion: The prevalence of Allergies, Asthma and Leucorrhea were maximum among them.
Prevalence of hypertension and associated risk factors among Nomad Tribe groups
Bandana Sachdev
Antrocom : Online Journal of Anthropology , 2011,
Abstract: Background: Hypertension is strongly correlated with modifiable risk factors such as adiposities, age, stress, high salt intake, Overweight and obesity is conveniently determined from BMI and visceral adiposity is determined by waist circumference. On the other hand, genetic factor has been established as an important non–modifiable predisposing factor. And ABO blood group is one such factor which needs to be investigated. Objectives: To study the prevalence rate of hypertension and various associated risk factors among few select endogamous group of Tribal Population. Methods: Cross-sectional, Tribal population-based study, consisting of a total sample of twelve hundred and eighty-six discrete subjects of age ≥18 years was chosen. BMI, waist circumference, ABO blood group, systolic and diastolic blood pressure were determined and correlated with each other. Results: The results were analyzed by applying correlation analysis and chi-square test. This study revealed that the prevalence of hypertension was high among the entire select tribe groups but seen highest in frequency in Bhopa (31%). It further showed that the subjects with blood group B had high blood pressure in the entire tribal groups except Bhopa Tribe. Conclusion: This study provides population based study on hypertensive tendency among select few endogamous tribal populations.
Construction and Characterization of a Chloroplast Targeting Plasmid DNA Vector in Nicotiana tabacum
Mahipal Singh,Bandana Dhiman
Journal of Biotech Research , 2009,
Abstract: A chimeric plasmid DNA vector designated as pMS65LBgus was constructed with the aim of targeting chloroplasts in Nicotiana tabacum. The Plasmid was designed to contain β-glucuronidase (gusA) gene under a modified chloroplast 16S rRNA gene promotor and a psbA gene terminator sequence. Adjacent to gusA gene, plasmid vector was designed to contain a selectable marker aminoglycoside 3’ adynyle-transferase (aadA) gene under atpA gene promotor and rbcL gene terminator sequences. The entire cassette with two genes was flanked by ~1.0 kb fragment on each side, spreading through 3’rps12 gene and orf131 of the tobacco chloroplast genome. Both gusA and aadA genes orient in opposite directions and are expressed in Escherichia coli. The entire cassette with aadA and gusA genes along with their expression signals can be excised by Nde I restriction endonuclease digestion. Multiple cloning sites at both ends of the gusA coding sequence enable a desired passenger gene to be replaced with gusA. PCR amplification, Southern hybridization, restriction mapping and dot blot analysis of the vector revealed a high degree of homology of the 2 kb tobacco chloroplast targeting fragment in the vector with various plant species, suggesting that the targeting vector may also be useful in other plants.
Second-Order Duality for Nondifferentiable Multiobjective Programming Involving ($Phi $, $ ho $)-Univexity
Ganesh Kumar Thakur,Bandana Priya
Journal of Mathematics Research , 2010, DOI: 10.5539/jmr.v2n4p33
Abstract: The concepts of ($Phi $, $ ho $)-invexity have been given by Carsiti, Ferrara and Stefanescu(Carsiti, G., et al 2006)We consider a second-order dual model associated to a multiobjective programming problem involving support functions and a weak duality result is established under appropriate second-order ($Phi $, $ ho $)-univexity conditions.
Second-order duality for nondifferentiable multiobjective programming involving (Φ,ρ)-univexity
Ganesh Kumar Thakur,Bandana Priya
Kathmandu University Journal of Science, Engineering and Technology , 2011, DOI: 10.3126/kuset.v7i1.5426
Abstract: The concepts of (Φ, ρ)-invexity have been given by Carsiti,Ferrara and Stefanescu[32]. We consider a second-order dual model associated to a multiobjective programming problem involving support functions and a weak duality result is established under appropriate second-order (Φ, ρ)-univexity conditions. AMS 2002 Subject Classification : 90C29; 90C30; 90C46. Key words : Second-order (Φ, ρ)-(pseudo/quasi)-convexity; multiobjective programming; second-order duality; duality theorem. DOI: http://dx.doi.org/ 10.3126/kuset.v7i1.5426 KUSET 2011; 7(1): 92-104 ?
Development and validation of stability indicating HPLC method for the estimation of 5-Fluorouracil and related substances in topical formulation
Sriguru Bandana,Nandha NP,Vairale AS,Sherikar AV
International Journal of Research in Pharmaceutical Sciences , 2010,
Abstract: A sensitive HPLC method has been developed and validated for the determination of 5-Fluorouracil (5-FU) and related substances in a novel topical formulation. The highly polar molecule requires aqueous mobile phase for the elution and separation of 5-Fluorouracil and its impurities (Impurity A, B and C official in EP). The developed method is found to be specific, reproducible, and stability indicating. The Phenomenex Synergi Polar RP 250×4.6mm 4μ column was used and mobile phase consisted of 0.1M potassium di hydrogen phosphate (KH2PO4) buffer to achieve good resolution and retention of the analyte and its impurities. The detector linearity was established from concentrations ranging from 0.01 μg/ml to 500 μg/ml for 5-Flurouracil and from 0.01 μg/ml to 0.08 μg/ml for related substances with a correlation co-efficient of 0.999. The relative response factor (RRF) values of impurity A, impurity B and impurity C determined from linearity plots were 1.9, 0.9 and 1.4 respectively. The limit of detection (LOD) and limit of quantification (LOQ) found to be in a range of 0.004μg/ml and 0.014μg/ml for 5-Fluorouracil and related substances respectively. The molecule was stable in all the stress conditions such as acid, base, oxidation, heat and photolysis as per the recommendations of ICH guidelines. The method was proved to be robust with respect to changes in flow rate, pH and column temperature. The proposed method is found to be sensitive, precise, rapid, reproducible, and offers good column life.
Characterization of a highly repetitive DNA sequence in Camellia sinensis (L.) O. Kuntze genome
Mahipal Singh,Bandana Dhiman,Chandan Sharma
Journal of Biotech Research , 2011,
Abstract: Tea is a widely consumed non-alcoholic natural beverage grown mostly in tropical asia and Africa. It is a vegetatively propagated crop and thus has low genetic variability. Repetitive DNA sequences in the genome, although, are commonly recognised very useful to differentiate individuals, they have not been explored extensively in tea genome. Here we report characterization of novel repetitive motiffs in a genomic DNA clone, designated as pMST11. It was isolated and sequenced from a genomic library of Camellia sinensis (L.) O. Kuntze by reverse genomic hybridisation approach. Sequence analysis of the insert displayed a highly A+T rich (66.8%) fragment of 894 base pairs (bp) containing a 168 bp single open reading frame in minus strand. The insert exhibited twelve 15-45 bp long direct repeats, of which, six were novel, non-overlapping and more than 30 bp long. The insert sequence of the clone displayed two unique microsatellite loci, having dinucleotide repeats (AG)15 and (AG)17. Interestingly, both microsatellites contained a 15 bp-consensus sequence attached to their 3' ends. Hybridization of the pMST11 clone with the tea genomic DNA, digested individually with 17 restriction endonucleases, exhibited a continuous smear suggesting that one or more repeats are highly dispersed through-out the tea genome. Dot blot analysis of the 894 bp insert sequence with genomes of 10 out of 12 different plant species exhibited positive signals of various intensities. Human and animal genomes exhibited negligible signals suggesting plant-specific nature of the repeats. The role of these repeat sequences in context of evaluating genetic variation in vegetatively propagated tea is discussed.
PalmPred: An SVM Based Palmitoylation Prediction Method Using Sequence Profile Information
Bandana Kumari, Ravindra Kumar, Manish Kumar
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0089246
Abstract: Protein palmitoylation is the covalent attachment of the 16-carbon fatty acid palmitate to a cysteine residue. It is the most common acylation of protein and occurs only in eukaryotes. Palmitoylation plays an important role in the regulation of protein subcellular localization, stability, translocation to lipid rafts and many other protein functions. Hence, the accurate prediction of palmitoylation site(s) can help in understanding the molecular mechanism of palmitoylation and also in designing various related experiments. Here we present a novel in silico predictor called ‘PalmPred’ to identify palmitoylation sites from protein sequence information using a support vector machine model. The best performance of PalmPred was obtained by incorporating sequence conservation features of peptide of window size 11 using a leave-one-out approach. It helped in achieving an accuracy of 91.98%, sensitivity of 79.23%, specificity of 94.30%, and Matthews Correlation Coefficient of 0.71. PalmPred outperformed existing palmitoylation site prediction methods – IFS-Palm and WAP-Palm on an independent dataset. Based on these measures it can be anticipated that PalmPred will be helpful in identifying candidate palmitoylation sites. All the source datasets, standalone and web-server are available at
Clinical Expression of an Inherited Unbalanced Translocation in Chromosome 6
Bani Bandana Ganguly,Vijay Kadam,Nitin N. Kadam
Case Reports in Genetics , 2011, DOI: 10.1155/2011/396450
Abstract: Unbalanced chromosomal rearrangements are not common; however, they have a significant clinical expression. The parental balanced translocation produces unbalanced chromosome, which is transmitted to next generation through fertilization of gametes carrying the derivative chromosome. The carriers of balanced rearrangements mostly do not have recognizable phenotypic expression. We report a family comprising of healthy and non-consanguineous young parents and their preemie newborn severely affected with congenital anomalies and systemic disorders. Conventional Gbanding analysis of somatic chromosomes identified a balanced translocation, t(6;10)(p23;q24), in mother and an unbalanced rearrangement, der(6)t(6:10)(p23;q24)mat, in the child. The child has inherited a derivative chromosome 6 with partial deletion of 6(p23-pter) and partial trisomy 10(q24-qter), which has resulted in fusion of genes of two different chromosomes. The prominent phenotypic features of del(6p), including high forehead, flat nasal bridge, agenesis of left ear, atrial septal defect (ASD), craniosynostosis, and growth retardation, are overlapping with specific Axenfeld-Reiger-, Larsen-, and Ritscher-Sinzel/3-C syndromes, however, lacking in ocular anomalies, skeletal laxity, or cerebellar malformation. Therefore, this paper rules out the isolated effect of del(6p23) or trisomy 10(q24) on distinct previously reported syndromes and proposes the combined effect of unbalanced chromosomal alteration.

Copyright © 2008-2017 Open Access Library. All rights reserved.