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匹配条件: “Bahador A” ,找到相关结果约460053条。
Commemoration of 1000th liver transplantation in Shiraz Center
A Bahador
International Journal of Organ Transplantation Medicine , 2011,
Abstract: The 10th Congress of Iranian Society for Organ Transplantation (IRSOT 2011) was held in Shiraz in May 17–19, 2011. Most of the scientific staff of Iranian Transplantation wards and many colleagues who have been involving in transplantation from the Middle East, United States and other countries participated in this Congress. During the Congress, on evening of May 18, in commemoration of 1000 liver transplantations in Shiraz, a group of people gather together to celebrate this great event. All Congress participants, chairmen of transplant wards, social and official managers of Shiraz and families of donors and recipients took part in this feast. Dr. S. A. Malek-Hosseini, Chairman of Shiraz Organ Transplant Center briefly gave a report on history and progression of the Shiraz Transplant Center. The first liver transplant was performed in 1993, before deceased donor approval law in Iranian parliament (2000) and Iranian transplant organ procurement organization (2002). Obtaining the consent from the deceased donor families was based on a religious decree of the late Imam Khomeini (1989). The first living related liver transplantation was performed in 1996 and up to 2011, 165 cases have been transplanted. The first split liver transplantation was done in 2002 and up to 2011, 56 cases have been trans-planted. In his report, Dr. Malek-Hosseini mentioned that half of the transplanted livers and all of the transplanted kidneys from deceased donors were harvested from the South of Iran network. In Shiraz Transplant Center, more than 80% of kidney transplants were performed from deceased donor since 2009. The goal of this celebration was to glorify of deceased donors families. The ceremony was attend ed by a sizable number of families of organ donors and recipients. It was highlighted by emotional speech of recipients and donor families. Some of donors’ families, for the first time faced with the recipients who live with liver or kidney of their beloved ones, this confrontation was a unique oc-casion that impressed all participants. In this ceremony, services of the special guest of the Congress, Professor J. Fung from Cleveland Clinic of USA, and the retired colleagues of Shiraz Organ Transplant Center were also appreci ated
Local Langerhans cell histiocytosis (eosinophilic granuloma) in a six-month baby: a case report
Bahador M,Esmaeilpoor S,Bahador M,Ebrahimi nezhad A
Tehran University Medical Journal , 2008,
Abstract: "nBackground: Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the proliferation of specialized bone marrow-derived Langerhans cells and mature eosinophils. The estimated annual incidence ranges from 0.5-2 cases per 100,000 persons per year. The pathogenesis of LCH is unknown. The prevalence of LCH seems to be higher among whites and males. The most common complaints at presentation are those related to bone lesions. Treatment consists of surgery, chemotherapy and radiotherapy alone or in combination. The age of onset varies according to the variety of LCH. Solitary lesions may occur in bones or skin. Cutaneous lesions present with firm, painless papulonodules or vesicles. "nCase report: This six-month-old baby presented with firm papulonodules on her temporal skin, but fortunately her other organs were healthy. She underwent two surgeries, separated by a one-month interval. Due to local recurrence after a short period of time, she underwent a 10-Gy dose of radiation. Her response proved good during follow-up. "nConclusion: Radiotherapy is good for controlling local recurrence in LCH, with few sequelae related to treatment.
The Impact of Integration of Instructional Systems Technology into Research and Educational Technology  [PDF]
Baharak Makki, Bahador Makki
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.32043
Abstract: This paper aims at presenting a review about instructional system technology integration in educational literature. Transitional periods of educational technology are discussed and principles of integration of instructional technology in educational technology are reviewed.
Prevalence of MBL-producing Pseudomonas aeruginosa isolated from burn patients
Mirsalehian A,Nakhjavani F,Bahador A,Jabal ameli F
Tehran University Medical Journal , 2011,
Abstract: "n 800x600 Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 st1":*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} Background: Pseudomonas aeruginosa is an important opportunistic pathogen causes clinical infections among burn patients. Metallo-β-lactamases (MBLs) are important mechanisms of Carbapenem (drug of choice) resistance among Pseudomonas aeruginosa isolates. The aims of this study were to determine the antibiotic susceptibility pattern and to detect the prevalence of MBLs among Pseudomonas aeruginosa"n"nMethods: Initially, the antibiotic resistance patterns of 170 clinical strains isolated from burn patients in Motahari Hospital in Tehran, Iran were determined by Kirby-Bauer disc diffusion method. All of the clinical isolates using two phenotypic and genotypic methods. Pseudomonas aeruginosa isolates resistant to Imipenem were screened for production of MBL by E test with Imipenem / Imipenem plus EDTA (E test MBL). PCR assay was performed for detection of blaVIM genes."n"nResults: Based on the study results, the percentage of resistance was as below: Imipenem (10 μg) 52.9%, Amikacin (30 μg) 81.7%, Carbenicilin (100 μg) 74.7%, Polymixine B (300 unit) 10%, Ticarcilin (75 μg) 84.7%, Tobramycin (10 μg) 88.2%, Colisitin (10 μg) 34.1, Colisitin (25 μg) 28.3%. Of 90 Carbapenem resistant isolates, 10(11/1%) isolates were positive by E test, all were sensitive to Colisitin and Polymixine B. All of the Imipenem resistant Pseudomonas aeruginosa isolates were examined by PCR for the presence of the blaVIM genes. All MBL-producing isolates carried blaVIM-1 genes."n"nConclusion: Considering the high prevalence and clinical importance of MBL-producing isolates, rapid identification of them and use of the appropriate infection control measures are necessary to prevent further spread of infections by these organisms.
Peripheral Blood Mononuclear Cell Mycobacterium tuberculosis PCR sensitivity in diagnosis of Tuberculosis
Hajiabdolbaghi M,Allishah H.A,Rasoolinejad M,Bahador A
Tehran University Medical Journal , 2008,
Abstract: Background: Tuberculosis is still one of the most important causes of mortality and morbidity in many countries and is the second only to human immunodeficiency virus as a cause of death worldwide resulting from a single infectious agent. In 1993, the World Health Organization declared tuberculosis a global public health emergency. Conven-tional methods for the diagnosis of Mycobacterium tuberculosis (MTB) infections are time consuming, as MTB culture requires 3-8 weeks for growth. To determine the sensitivity of polymerase chain reaction (PCR) in peripheral blood mononuclear cells (PBMC), we have evaluated Mycobacterium tuberculosis DNA in peripheral blood samples with PCR technique in adults with new cases of pulmonary and extra-pulmonary tuberculosis. Setting: Department of Infectious disease of Imam Khomeini Hospital, 2004- 2005, Tehran, Iran.Methods: In this cross-sectional study, we evaluated MTB DNA extracted from 3ml citrated peripheral blood samples from 95 adults with new cases of pulmonary and extra-pulmonary tuberculosis. DNA extraction was performed using a commercial PCR kit with IS1081 primers. For prevention of cross contamination and reduction of false positives, all steps were performed under laminar hood.Results: The 95 patients, 59 of whom were male, had a mean age 44.44 years (SD±20.26); 69 cases had pulmonary and 26 had extra-pulmonary tuberculosis. PCR was positive in 32 (33.7%) patients and negative in 63 (66.3%) cases. The overall sensitivity and accuracy of the PCR assay was 44.1% for pulmonary, 19.2% for extra-pulmonary and 10% for disseminated tuberculosis, respectively.Conclusion: The low sensitivity of the IS1081 primer MTB-PCR assay on PBMC may pose problems for the rapid diagnosis of tuberculosis. However, further studies are needed to confirm this technique as an alternative test for the diagnosis of tuberculosis.
Smoking Prevalence and Associated Factors to Quit among Tabriz Dormitory University Medical Students, Tabriz, Iran
Shamsipour M.,Korani Bahador R.,Mohammadpoorasl A.,Mansouri A.
Qom University of Medical Sciences Journal , 2012,
Abstract: Background and Objectives: Cigarette smoking as a major public health problem contributes extra health costs, and smoking cessation among youths is a priority for any prevention program. This study aimed to determine the prevalence of smoking and examined factors associated with having attempts to quit smoking and the motivations to quit among medical university students. Methods: A cross-sectional survey using a random sampling was carried out among 523 (293 male, and 246 female, aged 22.48±3.33years) students in Tabriz University of Medical Sciences. Data were collected by using a self-administered questionnaire. The data were analyzed by t-test, chi-square test and Fisher exact tests.Results: The overal prevalence of smoking was 8.9%. (male 18% and 1.4% female). There were significant relationships between smoking status with male gender and alcohol consumption (p<0.001). The reasons for smoking initiation were: satisfying their curiosity, new experience (37.76%), pleasure and entertainment (17.48%), mental, emotional problems and sedation (16.08%), smoker friends (15.38%), inexperience and ignorance (4.89%). 54.16% of the current smokers had a history of smoking cessation.Conclusion: Regarding the higher prevalence of cigarette smoking in students, especialy in male and attempting to quit smoking in majority of them, preventive interventions in younger age and providing cigarette smoking cessation services for students seem necessary.
Prevalence of Chlamydia Trachomatis and Mycoplasma Genitalium in Pregnant Women of Sabzevar- Iran
M Haghighi Hasanabad,M Mohammadzadeh,A Bahador,N Fazel
Iranian Journal of Microbiology , 2011,
Abstract: Background: As prenatal screening for sexually transmitted infections and treatment of infected pregnant women is not routinely performed in Iran and prevalence of two sexually transmitted pathogens, Chlamydia trachomatis and Mycoplasma genitalium, in Sabzevar (east of Iran) is unknown, we decided to perform this prospective study.Methods: One hundred ninety-six urine specimens of pregnant women attending the specialized maternity hospital of the city were collected and tested by duplex PCR.Results: A total of 31 specimens were positive (15.81%) (27 Chlamydia trachomatis isolates, 13.77%; and 2 Mycoplasma genitalium isolates, 1.02%). Co-infection with both species was detected in 2 specimens (1.02%). A significant correlation was found between preterm labor and infection (P-value ≤ 0.05).Conclusion: The present study shows high prevalence of Chlamydial infections in comparison with Mycoplasma genitalium in this region. Further studies with larger sample size and more focused on different groups at risk are needed for a movement towards prevention and control of sexually transmitted infections (STIs).
Detection of Chlamydia trachomatis and Mycoplasma genitalium in semen samples of infertile men using multiplex PCR
Sadrpour P,Bahador A,Asgari S,Bagheri R
Tehran University Medical Journal , 2013,
Abstract: Background: Chlamydia trachomatis is the most common bacterial sexually transmitted infection in the world, but the effect of this infection on male fertility is still controversial. Despite reports of interaction between Mycoplasma genitalium and sperm, this pathogen in semen samples of infertile men is less studied. We studied, the prevalence of Chlamydia trachomatis and Mycoplasma genitalium infection in infertile men.Methods: Among attending Avicenna Infertility Center, 120 men who had abnormal semen analysis tests were selected and the samples were taken. After detailed analysis of semen quality, DNA was extracted from each sample by chelex. Samples were evaluated for these two pathogens by multiplex PCR. Results were statistically analyzed.Results: Chlamydia trachomatis and Mycoplasma genitalium was detected in 23/3% and 12/5% of the samples, respectively. Although, Mycoplasma genitalium infection rises by increasing (P=0.640) and decreasing in age of first sexually activity (P=0.203), and also positive cases of Chlamydia trachomatis infection showed increase regarding age increase (P=0.619) and age decrease in first sexually activity (P=0.511), but these differences were not statistically significant. Conclusion: All in all, regarding to the increased prevalence of Chlamydia trachomatis infection compared with the only similar study in Iran and high prevalence of Mycoplasma genitalium infection in infertile men, this assessment was done. A multiplex PCR protocol rapidly and simultaneously identify these organisms in comparison with uniplex from clinical samples. Based on our results screening for Chlamydia trachomatis and Mycoplasma genitalium infection among infertile men seems to be valuable.
Production of Recombinant Streptokinase in E. coli and Reactivity with Immunized Mice
S. Mahmoudi,H. Abtahi,A. Bahador,G. Mosayebi
Pakistan Journal of Biological Sciences , 2010,
Abstract: Streptokinase (SK) is a potent plasminogen activator with widespread clinical use as a thrombolytic agent. In this study, we produce high level expression of recombinant streptokinase in E. coli by expression vector pET32a. Genomic DNA of streptokinase gene (SKC) was extracted, then amplified by polymerase chain reaction (PCR) method and sub-cloned to prokaryotic expression vector pET32a. Escherichia coli BL21 (DE3) pLysS were transformed with pET32a-skc and gene expression was induced by IPTG. The expressed protein was purified by affinity chromatography by Ni-NTA resin. High concentration of the recombinant protein obtained from the single-step purification by affinity-chromatography (Ni-NTA). The yield of recombinant streptokinase was nearly 470 mg L-1 of initial culture. Our data showed that production of recombinant streptokinase improved by pET32a in Escherichia coli.
Evaluation of Different Primer Sets for the Rapid Diagnosis of Tuberculosis
Fatolahzadeh,P. Maleknejad,A. Bahador,H. Peeri- Dogaheh
Pakistan Journal of Biological Sciences , 2007,
Abstract: Pleural fluid samples from patients with exudative effusion who were diagnosed with tuberculous pleuritis are examined using a new designed primer set based on IS1081 gene (IS1081-PCR) and rpoB-PCR. The PCR results are compared with the results of the sample cultures, using Loewenstein-Jensen (LJ) medium and Ziehl-Neelsen (ZN) staining. Of 78 cases that were confirmed as tuberculous pleuritis by histopathology, supported by sputum culture, biochemical markers (adenosine deaminase, gamma interferon and tumor necrosis factor), radiographic and clinical data, 61 (78.2%) were positive by IS1081-PCR, 43 (55.1%) by rpoB-PCR, 17 (21.7%) by culture and 3 (3.8%) by ZN stain. When IS1081-PCR test results were compared with the confirmed culture, the sensitivity, specificity, positive predictive value and negative predictive value for the IS1081-PCR were 94.1, 55.7, 37.2 and 97.1%, respectively. The corresponding values for the rpoB-PCR were 94.1, 26.2, 26.2 and 94.1%, respectively. When tests results were compare with the confirmed radiographic, histopathology, biochemical markers and clinical diagnosis of tuberculous pleuritis, the IS1081-PCR assay is more sensitive, specific and reliable than both rpoB-PCR assay and culture.

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