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Search Results: 1 - 10 of 193900 matches for " Ba?ak Karakurum G?KSEL "
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Late Onset Poststroke Seizures
Baak Karakurum GKSEL,Mehmet KARATA?,Meliha TAN,,Tülin YILDIRIM
Journal of Neurological Sciences , 2005,
Abstract: The most common cause of seizures is cerebrovascular disease in elderly population. Late onset seizures are not investigated as well as early onset seizures in patients with stroke. There is no common consensus about clinical, electrophysiological and radiological features of these seizures. In this study, 55 patients with late onset seizure who had stroke history were investigated. The 49 % of patients were women, the mean ages of patients were 63.9±9.2 years. The mean of duration between stroke and the first seizure was 30.4±36.8 months and the mean of following time was 14±13 months. The 89% of patients ischemic stroke and 11% of patients had hemorrhagic stroke. The lesion localizations were cortical in 17 (30.9%) patients, subcortical in 8 (14.5%) and cortico-subcortical in 29 (52.7%). As a result 84 % patients’ lesions were cortical localization. There were partial seizure in 39 (%70.9) patients, generalized tonic-clonic seizure in 16 (29.1%) patients. 43 (78%) patients had no seizure during antiepileptic therapy. 7 (12.7%) patients had seizure after beginning antiepileptic drug due to stopping drug, low blood level of drug and ineffectiveness of drug. 5 (9%) patients had not been given drug because of first seizure and no seizure during follow-up. In conclusion, the late onset poststroke seizures seem frequently in ischemic stroke, the reccurence rate was high and partial type seizures were more common than generalized and cortical localization was seen frequently. On the other hand, this condition has good prognosis.
Investigation of Frequency of Allergic Contact Dermatitis Due to Cosmetics in Patients with Acne Vulgaris
?pek Gürses Ko?,P?nar Yüksel Baak
Turkderm , 2010,
Abstract: Background and Design: Acne vulgaris is a chronic inflammatory disease of pilosebaceous unit. While some cosmetic products can trigger acne, topical and cosmetic agents used in the treatment of acne may cause allergic contact dermatitis. Therefore, the choice of cosmetic products is very important for the patients. Limited number of studies have been found in literature investigating allergic contact dermatitis due to only topical drugs in patients with acne vulgaris.Material and Method: In this research, it is aimed to find out the frequency of allergic contact dermatitis caused by cosmetics in patients with acne vulgaris. Fifty patients with acne vulgaris but without clinical signs of contact dermatitis and 50 control cases without contact dermatitis on admittance were included in the study. Skin patch tests of the European standard series (27 allergens) and cosmetic series (45 allergens) with IQ Chamber test materials were applied on the unlesional back of the patient and control groups. Materials with testing substances were taken out of skin 48 hours later and read after 30 minutes and at 72nd hour, as suggested by International Contact Dermatitis Research Group, and substances leading to reactions were recorded.Results: Sensitivity to sorbitan monooleate, in the cosmetic series, was found to be significantly higher in the patient group (p=0,022). While no statistical difference except for sorbitan monooleate was detected in the patient and control groups, it was found that the patient group reacted positively to more allergens than the controls. Conclusion: In conclusion, because of abundance of allergens detected with patch test in the patient group, it may be suggested that cosmetic products might be responsible for the development of allergic contact dermatitis in patients with acne vulgaris. In addition, we believe that furthering studies with groups of numerous patients are needed to support our results.
A Case of Eosinophilic Ulcer Localized at Lower Lip
Hicran Yetkin,P?nar Yüksel Baak,Vahide Baysal Akkaya,Gülsün ?nan
Turkderm , 2009,
Abstract: Eosinophilic ulcer of the oral mucosa is an uncommon, benign and self-limiting disease. Although exact pathogenesis of the disease is unknown, trauma is thought to play a role in the etiology. Eosinophilic ulcer is characterised by an ulcer with an indurated border, commonly occurring on the tongue but also on any region of the lips and oral mucosa. The ulcerated lesion with acute onset may heal spontaneously within 1 week to 8 months. A 23 year-old-man man was admitted for painful ulceration on the lower lip for seven years which flares up during summers and heals spontaneously. Clinical and histopathological findings of the case, consistent with eosinophilic ulcer, is presented because of its rare occurrence as well as clinical resemblance to squamous cell carcinoma of the lower lip.
Investigation of Serum Leptin Levels in Psoriatic Patients
Türkan G?nül,P?nar Yüksel Baak,Yusuf Kara,Vahide Baysal Akkaya
Turkderm , 2009,
Abstract: Background and Design: Psoriasis is a chronic, T cell mediated hyperproliferative skin disease. Leptin is an adipokine that stimulates Th1 immune response while suppressing Th2 immune response. Because that leptin plays an important role in the T cell immunity, it is aimed to investigate the relation between psoriasis and leptin and whether leptin plays a role in the immunopathogenesis of psoriasis in the present study. Mateiral and Method: Serum leptin, interleukin (IL)-1b, IL-6, IL-8, TNF-a and nitric oxide (NO) levels were measured in 54 psoriatic patients and age, sex and body mass index matched 50 healthy control subjects. Results: The mean serum leptin concentration was not statistically different in psoriatic patients compared with the controls (p=0.568). Serum leptin levels were not correlated with PASI score, duration and clinical type of the disease as well as IL-1b, IL-6, IL-8, TNF-a and NO levels. IL-8 and TNF-a levels were significantly higher in patients with psoriasis than healthy control subjects (p=0.002 and p=0,020 respectively). The mean serum IL-1b, IL-6 and NO levels were not statistically different in patients when compared with control subjects. Conclusion: These results showed that leptin may not play a significant role in the immunopathogenesis of psoriasis and leptin could not be accepted as a marker to assess severity of the disease.
A Case of Mucormycosis Presented with Oral Ulcers
P?nar Yüksel Baak,Emel Sesli ?etin,Hicran Yetkin,Vahide Baysal Akkaya
Turkderm , 2009,
Abstract: A 62-year-old male patient suffering from oral ulcers and painful throat with pancytopenia was diagnosed as acute myeloid leukemia. Because of uncontrolled fever despite antibiotherapy and that Rhizopus spp. was identified from oral lesions, amphotericin B was added to treatment for two weeks. Oral lesions were completely cleared thereafter and this case was presented to point out that mucormycosis must be kept in mind in the differential diagnosis of oral mucosal lesions in patients with immunosuppression as well as it is a rare disease with high mortality.
Ruptured Ectopic Pregnancy in a Patient with Bilateral Tube Ligation
Turkish Journal of Emergency Medicine , 2012,
Abstract: Tubal sterilization is a commonly used method of contraception. In the case of sterilization failure, the rate of intrauterine pregnancy is higher than that of ectopic pregnancy. In this article, we present a case of ruptured ectopic pregnancy with a previous history of bilateral tube ligation, presented to our hospital. We aim to underline the necessity of primarily considering ectopic pregnancy as a cause of abdominal pain, even in the presence of tube ligation history in females with childbearing potential.
Spontaneous Coronary Artery Dissection in a Patient with Henoch -Sch nlein Purpura
Zeki ?im?ek,Gksel Acar,Elnur Alizade,Mustafa Ak?akoyun
Ko?uyolu Kalp Dergisi , 2009,
Abstract: Henoch-Sch nlein purpura is a small vessel vasculitis that affects mainly the skin, joints, gastrointestinal tract and kidneys. The cardiovascular system is also rarely affected . We describe a 47-year-old man with Henoch-Sch nlein purpura who developed anteroseptal myocardial infarction. The coronary angiography revealed coronary dissection at the level of second diagonal branch of left anterior desending artery as the culprit lesion. The region of dissection and the proximal lesion was successfully treated by stenting. The myocardial infarction on the basis of spontaneous coronary dissection in the present case with established Henoch-Sch nlein purpura, may be the first to be described.
The Effect of Valsartan on Heart Rate Variability and Heart Rate Recovery in Patients with Mild to Moderate Mitral Stenosis
Hekim Karap?nar,?zlem Batukan Esen,Mustafa Ak?akoyun,Gksel A?ar
Ko?uyolu Kalp Dergisi , 2010,
Abstract: Summary: Atrial fibrillation (AF) is known to be one of the most important complications of mitral stenosis (MS). It has been reported that autonomic nervous system (ANS) had an effect on AF development, heart rate variability (HRV) and heart rate recovery (HRR) were under the control of ANS, and their disorders were present in MS. We studied the effect of Valsartan on HRV and HRT, and thus its effect on ANS. Methods: Eleven patients (39±8 years, 10 females) with mild to moderate MS were included in the study. Sixteen volunteers (38±8 years, 14 females) matched for age and sex were selected for control group. All subjects underwent transthoracic echocardiography (TTE), symptom-limited treadmill test and 24 hour Holter monitorization.The patients were administered 160 mg of Valsartan daily for 14 weeks. TTE, treadmill test and Holter monitorization were repeated at the end of treatment period. In Holter monitorization, the time and frequency domain analysis of HRV and in exercise test, HRR at first and third minutes (HRR1 and HRR3) were examined. Results: Before Valsartan treatment, no significant difference was found in HRR and HRV parameters between the two groups. Systolic and diastolic blood pressure, and also HRR1values were significantly decreased after treatment of Valsartan (117±6 vs. 107±4 mmHg p<0.002, 76±6 vs. 69±9 mmHg p<0.044, 44±14 vs. 33±12 p< 0.014, respectively), while the exercise time was significantly increased (786±114 vs. 846±95 sn p< 0.044). In Holter analysis neither time nor frequency domain of HRV parameters showed a meaningful change. Conclusion: In moderate MS, treatment with Valsartan improved the effort capacity, while autonomic function parameters have been defined on the base of HRV and HRR were not significantly different.
The Conus Artery Arising from Posterolateral Branch of the Right Coronary Artery; A Case Report
Mustafa Ak?akoyun,?zlem Esen,Zeki ?im?ek,Gksel A?ar
Ko?uyolu Kalp Dergisi , 2010,
Abstract: Congenital coronary anomalies are relatively uncommon, with a prevalence varying from 0.3% of autopsy series to 1.3% of angiographic studies. We report a case of a conus artery originating from posterolateral branch of the right coronary artery. The anomaly was discovered incidentally during cardiac catheterization. Such an anomalyis identified for the first time.
Vanishing white matter leukodystrophy, a rare case report
Serhat Güler,Adnan Yüksel,Ak?n ??can,?lhan I??k
Turk Pediatri Ar?ivi , 2013,
Abstract: ...
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