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Search Results: 1 - 10 of 939 matches for " BRENDA; MONACHE "
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PROPIEDADES ANTIVIRALES DE COMPUESTOS NATURALES Y SEMI-SINTETICOS DE LA RESINA DE HELIOTROPIUM FILIFOLIUM
RENE TORRES,BRENDA MODAK,ALEJANDRO URZúA,FRANCO DELLE MONACHE
Boletín de la Sociedad Chilena de Química , 2002,
Abstract: Del producto mayoritario del exudado resinoso de Heliotropium filifolium ( Fam. Boraginacea), el inusual alcohol espiránico filifolinol 1, se sintetizó el compuesto, no previamente descrito, filifolinona 3. Estos dos, junto al también aislado previamente de H. filifolium , senecionato de filifolinol 2, fueron ensayados en sus antividades antivirales frente a cepas de cinco virus, productores de enfermedades en seres humanos. El filifolinol resultó ser el más activo frente al virus de la poliomelitis, pero con una estrecha relación entre la dosis antiviral y la citotóxica A new compound called filifolinone 3 was synthesized from the unusual spiranic alcohol filifolinol 1, the principal compound isolated from the resinous exudate of Heliotropium filifolium. (fam.Boraginaceae) Both compounds and the ester derivative of 1, filifolinyl senecionate 2 were tested as antiviral agents against five virus species of importance in human diseases. The most active compound resulted 1, specially against polio virus, but with a tight relationship between antiviral dosis/cytotoxic dosis
ANTIOXIDANT PROPERTIES OF LIGNANS AND FERULIC ACID FROM THE RESINOUS EXUDATE OF LARREA NITIDA
TORRES,RENé; URBINA,FRANCISCO; MORALES,CLAUDIA; MODAK,BRENDA; MONACHE,FRANCO DELLE;
Journal of the Chilean Chemical Society , 2003, DOI: 10.4067/S0717-97072003000300012
Abstract: from the resinous exudate of twigs end leaves of larrea nitida, two lignans nor isoguaiacine 1 and meso-nor-dihydroguaiaretic acid 2 and ferulic acid 3 were isolated. the antioxidant activities of resin and pure compounds were assesed by bleaching of the abts derived radical-cation
PROPIEDADES ANTIVIRALES DE COMPUESTOS NATURALES Y SEMI-SINTETICOS DE LA RESINA DE HELIOTROPIUM FILIFOLIUM
TORRES,RENE; MODAK,BRENDA; URZúA,ALEJANDRO; DELLE MONACHE,FRANCO; DAMONTE,ELSA; PUJOL,CARLOS A.;
Boletín de la Sociedad Chilena de Química , 2002, DOI: 10.4067/S0366-16442002000300009
Abstract: a new compound called filifolinone 3 was synthesized from the unusual spiranic alcohol filifolinol 1, the principal compound isolated from the resinous exudate of heliotropium filifolium. (fam.boraginaceae) both compounds and the ester derivative of 1, filifolinyl senecionate 2 were tested as antiviral agents against five virus species of importance in human diseases. the most active compound resulted 1, specially against polio virus, but with a tight relationship between antiviral dosis/cytotoxic dosis
Nemorosonol B, A polyisoprenylated alkyl-aryl-ketone from clusia nemorosa
Franco Delle Monache
Bulletin of the Chemical Society of Ethiopia , 1990,
Abstract: Bull. Chem. Soc. Ethiop., 4(l), 67-69 (1990).
Nemorosonol B, A polyisoprenylated alkyl-aryl-ketone from clusia nemorosa
Franco Delle Monache
Bulletin of the Chemical Society of Ethiopia , 1990,
Abstract: Bull. Chem. Soc. Ethiop., 4(l), 67-69 (1990).
The Impact of Cattle Grazing in High Elevation Sierra Nevada Mountain Meadows over Widely Variable Annual Climatic Conditions  [PDF]
Lindsey Myers, Brenda Whited
Journal of Environmental Protection (JEP) , 2012, DOI: 10.4236/jep.2012.328097
Abstract: The impact of summer cattle grazing on water quality during three very different climatic years in the Sierra Nevada was investigated. Water year 2009 had near normal precipitation; 2010 had late precipitation and snowmelt; and 2011 had 150% above normal precipitation. Surface waters were tested for pathogenic bacteria indicators fecal coliform, E. coli, and total coliform before and after cattle were released onto summer grazing allotments. Water samples were collected from meadow stream sites up to 6 weeks before and up to 6 weeks after cattle grazing began. Streams passing through ungrazed meadow served as controls. Eight sample sites were between 1694 m and 2273 m in elevation; one site was lower at 1145 m in elevation. Samples were transported within 6 hours to a water analysis laboratory, where samples were analyzed following standardized laboratory methods. Results showed that individual site and total mean concentrations of E. coli in surface waters were within regulatory standards before cattle arrived during each of the 3 study years. After the beginning of grazing, mean E. coli counts increased as follows: 2009 from 8 to 240 CFU/100mL, 2010 from 7 to 561 CFU/10mL; 2011 from 7 to 657 CFU/100mL (p < 0.05 all years). Total coliform bacteria and fecal coliform concentrations showed the same pattern. This study shows that cattle grazing in the high elevation Sierra Nevada results in a significant increase in indicator bacteria. This impact on the watersheds occurs despite widely variable annual climatic conditions.
Botulinum toxin type-A (BoNTA) and dynamic wrist-hand orthoses versus orthoses alone for the treatment of spastic-paretic upper extremity in chronic stroke patients  [PDF]
Sepideh Pooyania, Brenda Semenko
Open Journal of Therapy and Rehabilitation (OJTR) , 2014, DOI: 10.4236/ojtr.2014.21003
Abstract: Purpose: The purpose of this study was to investigate the potential functional improvement of the spastic-paretic upper extremity of individuals with chronic hemiparesis when using a dynamic wrist-hand orthosis with and without concurrent botulinum toxin type-A (BoNTA) injections into the spastic upper extremity muscles. Methods: A three-year retrospective chart review was conducted on all stroke patients referred to out-patient occupational therapy for an upper extremity rehabilitation program, which included use of a dynamic wrist-hand orthosis (DWHO). Three charts documented concurrent treatment with a DWHO + BoNTA. Eleven charts documented DWHO use without concurrent BoNTA treatment. Pre- and post-intervention outcome measure scores were compared between the two groups. Pre- and post-interven- tion scores were also analyzed irrespective of treatment group. Results: Although improvement approached significance on three of the documented outcome measures when comparing the DWHO + BoNTA and DWHO groups, no statistically significant changes were found. A significant difference (p < 0.05) however, was found between the pre- and post-intervention scores irrespective of treatment group in 13 of 14 of the outcome measures documented. Conclusions: Further research with a larger sample size is suggested to assess the combined effect of using a dynamic wrist-hand orthosis and BoNTA injections into the spastic upper extremity muscles of individuals with chronic hemiparesis post stroke.
Alternative Nitrogenases in Anabaena variabilis: The Role of Molybdate and Vanadate in Nitrogenase Gene  [PDF]
Teresa Thiel, Brenda S. Pratte
Advances in Microbiology (AiM) , 2013, DOI: 10.4236/aim.2013.36A011
Abstract: Anabaena variabilis ATCC 29413 has two distinct nitrogenases that function in heterocysts, a conventional Mo-nitrogenase and an alternative V-nitrogenase. Synthesis of these two enzymes was repressed in cells growing with a source of fixed nitrogen, such as ammonium; however, the V-nitrogenase was also repressed by Mo. Expression of the V-nitrogenase which was not affected by V and expression of the Mo-nitrogenase was not affected by the presence or absence of either Mo or V. In the absence of both Mo and V in an environment lacking fixed nitrogen, cells became starved for both metals; however, low levels of nitrogen fixation and slow growth persisted. A mutant lacking the V-nitrogenase was still able to grow very slowly in Mo-and V-free medium; however, loss of the Mo-nitrogenase in a nifDK1 mutant abolished the residual growth, suggesting that only the Mo-nitrogenase functioned under these conditions to support slow growth. The addition of vanadate, molybdate, or tungstate, which is transported by the molybdate transporter, to cells starved for these metals resulted in an increase in nitrogenase activity within two hours after the addition of the metal and this increase required new protein synthesis. While tungstate functioned about as well as vanadate in supporting acetylene reduction, the cells were not able to grow any better with tungstate than with no added metal. A mutant lacking the V-nitrogenase showed no increase in nitrogenase activity upon addition of tungstate, suggesting that the V-nitrogenase was able to incorporate tungstate. Tungstate was able to substitute for molybdate in repressing transcription of a Mo-transport gene, but it did not repress transcription of the vnfH gene, which was repressed by Mo. The availability of Mo and V plays an important role in controlling whether the Mo-or the V-nitrogenase is used for nitrogen fixation.
Nintendo® Wii™ and a Physical Activity Routine: Effective Therapeutic Interventions in the Older Adult Population?  [PDF]
Elizabeth A. Fain, Brenda Kennell
Open Journal of Nursing (OJN) , 2014, DOI: 10.4236/ojn.2014.48060
Abstract:

Occupational therapists work with individuals across the lifespan to promote health and wellness. “Occupational therapy promotes health and wellbeing through active involvement in meaningful occupations. By helping clients eliminate barriers, enhance their self-management skills, improve their performance of daily activities and adopt healthy habits and routines, occupational therapy unlocks the door to participation across the lifespan” (AOTA, 2010). In today’s world, health and wellness-related services are in demand for those aged 65 and older. As life expectancy rates continue to rise, there is an increase in concern for the field of occupational therapy to find a successful and efficient way to meet the needs of the growing number of older adults (National Center for Health Statistics, 2006). The idea that physical activity can be a beneficial occupation in the elderly has been examined and proved effective as a means of enhancing the quality of life in this population. “Although functional impairments due to the aging process seem to be inevitable, functional limitations due to an inactive lifestyle might be reversed. Indeed, it has been suggested that physically active lifestyles may contribute to improving or maintaining health and wellness” (Fletcher, Gulanick, & Braun, 2005). The purpose of this study was to investigate the effects of two different physical activity programs on individuals aged 65 and older. The variables that were examined were functional skills (activities of daily living), balance skills, and overall upper extremity function. This study looked at two forms of physical activity to determine their individual effects on functional skills, balance, and overall upper extremity function in this population. The two physical activity interventions were the Nintendo Wii gaming system and a videotaped exercise routine.

Catching What We Can't See: Manual Interception of Occluded Fly-Ball Trajectories
Gianfranco Bosco, Sergio Delle Monache, Francesco Lacquaniti
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0049381
Abstract: Control of interceptive actions may involve fine interplay between feedback-based and predictive mechanisms. These processes rely heavily on target motion information available when the target is visible. However, short-term visual memory signals as well as implicit knowledge about the environment may also contribute to elaborate a predictive representation of the target trajectory, especially when visual feedback is partially unavailable because other objects occlude the visual target. To determine how different processes and information sources are integrated in the control of the interceptive action, we manipulated a computer-generated visual environment representing a baseball game. Twenty-four subjects intercepted fly-ball trajectories by moving a mouse cursor and by indicating the interception with a button press. In two separate sessions, fly-ball trajectories were either fully visible or occluded for 750, 1000 or 1250 ms before ball landing. Natural ball motion was perturbed during the descending trajectory with effects of either weightlessness (0 g) or increased gravity (2 g) at times such that, for occluded trajectories, 500 ms of perturbed motion were visible before ball disappearance. To examine the contribution of previous visual experience with the perturbed trajectories to the interception of invisible targets, the order of visible and occluded sessions was permuted among subjects. Under these experimental conditions, we showed that, with fully visible targets, subjects combined servo-control and predictive strategies. Instead, when intercepting occluded targets, subjects relied mostly on predictive mechanisms based, however, on different type of information depending on previous visual experience. In fact, subjects without prior experience of the perturbed trajectories showed interceptive errors consistent with predictive estimates of the ball trajectory based on a-priori knowledge of gravity. Conversely, the interceptive responses of subjects previously exposed to fully visible trajectories were compatible with the fact that implicit knowledge of the perturbed motion was also taken into account for the extrapolation of occluded trajectories.
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