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Editorial Vol.2(1)
BD Bhatia
Journal of Universal College of Medical Sciences , 2014, DOI: 10.3126/jucms.v2i1.10481
Abstract: DOI: http://dx.doi.org/10.3126/jucms.v2i1.10481 Journal of Universal College of Medical Sciences (2014) Vol.2(1)
Framing a Well-Structured Single Best Response Multiple Choice Questions (MCQs) - An Art to be Learned by a Teacher
N Chaudhary,BD Bhatia,SK Mahato
Journal of Universal College of Medical Sciences , 2014, DOI: 10.3126/jucms.v2i2.11176
Abstract: DOI: http://dx.doi.org/10.3126/jucms.v2i2.11176
Ebola Virus Outbreak: The Present Situation in South East Asia Perspective
S Chaudhary,VK Pahwa,BD Bhatia
Journal of Universal College of Medical Sciences , 2014, DOI: 10.3126/jucms.v2i3.11819
Abstract: No abstract DOI: http://dx.doi.org/10.3126/jucms.v2i3.11819 Journal of Universal College of Medical Sciences Vol.2(3) 2014: 1-2
Papillary glioneuronal tumor: a new entity awaiting inclusion in WHO classification
BD Radotra, Yashwant Kumar, Alka Bhatia, Sandeep Mohindra
Diagnostic Pathology , 2007, DOI: 10.1186/1746-1596-2-6
Abstract: Tumors of mixed glioneuronal type like gangliocytoma, dysembryoplastic neuroepithelial tumor, ganglioglioma, anaplastic ganglioglioma and central neurocytoma are well recognized in the central nervous system [1]. In the year 1998 a new variant of mixed glioneuronal tumor was described by Komori et al. [2] which is still not included as a separate entity in the WHO classification. It was composed primarily of glioneuronal elements with prominent pseudopapillary structures. This unusual mixed glioneuronal tumor of the central nervous system was called papillary glioneuronal tumor (PGNT). The pseudopapillae are usually composed of hyalinized vessels covered by a single or stratified layer of glial fibrillary acid protein (GFAP) positive astrocytes. The cells forming neuronal elements include neurocytes, ganglioid cells or ganglion cells within the neuropil which are synaptophysin positive. To date 32 cases of PGNT have been reported in the world literature. We report the 33rd case with a review of the literature.The patient was a 41-year-old male who presented with pain in the nape of the neck of one week duration in December 2005. Also there was a history of headache on and off for the past one year and vertigo for two and a half years. Magnetic resonance imaging showed a predominantly solid tumor with ill defined margins. The mass showed a heterogeneous hyper-intense signal on T2 weighted images with no obvious cystic degeneration. It was occupying the cerebral parenchyma of the left temporal and parieto-occipital regions. There was involvement of posterior part of body and splenium of the corpus callosum with extension of the lesion across midline to the right parietal region. The left side of midbrain, thalamus and basal ganglia appeared distorted along with tentorial herniation. The posterior part of the body of the left lateral ventricle was compressed and the third ventricle was displaced to the right side. The tumor was close to but did not reach the cortical s
Non invasive trans-cutaneous bilirubin as a screening test to identify the need for serum bilirubin assessment in healthy term neonates
BK Gupta,N Chaudhary,BD Bhatia,Binod Gupta
Journal of Universal College of Medical Sciences , 2013, DOI: 10.3126/jucms.v1i4.9567
Abstract: INTRODUCTION: Hyperbilirubinemia is a common problem in the neonates. It can progress to develop kernicterus unless intervention is initiated. Severity of jaundice and decision for management are usually based on total serum bilirubin (TsB) estimation which technique and results closely correlates with total serum bilirubin levels. OBJECTIVES: To compare the accuracy of visual assessment of jaundice by single trained observer based on Kramer's index with total serum bilirubin levels in healthy term neonates. To compare accuracy of non invasive bilirubin assessment with serum bilirubin levels, to compare trans-cutaneous bilirubin assessment on different sites (forehead and sternum) and to develop a cutoff point oftrans-cutaneous bilirubin level for serum bilirubin assessment. METHODS: This prospective study was conducted in the Neonatal unit of the department of Paediatrics at Kasturba Hospital ,Manipal. Study period was from October 2007 to June 2008. Clinical assessment of jaundice was done in healthy term neonates by observer (Trained Paediatric Post Graduate Resident) based on Kramer's index. Transcutaneous bilirubin assessment was done on the forhead and sternum of each baby using JM-103 Minolta. Air shields bilirubino meter. Serum bilirubin level was measured within 30 minutes of the clinical assessment for each baby. RESULTS: This study included 187 healthy term neonates. The mean birth weight was 2856.83gm ± 493.89gm and mean gestation was 38.25+ 1.030 SD. Clinical assessment and Transcutaneous bilirubin(TcB) significantly correlated with total serum bilirubin (TsB), with correlation co-efficient of 0.757 and 0.801 respectively (p 0.0001). Transcutaneous bilirubin assessment over forehead showed a tendency to under estimate total serum bilirubin, with mean difference of-0.31 mg/dl, SD 1.75 mg/dl with 95% confidence interval ofthe mean -0.60 and -0.02 mg/dl (p value 0.05).Transcutaneous bilirubin assessments between 10 mg/dl to 15 mg/dl correlated accurately with total serum bilirubin levels avoiding blood sampling. CONCLUSION: Trained observer clinical assessment of jaundice can be used for screening neonatal jaundice. Non invasive transcutaneous bilirubin assessment has demonstrated significant accuracy with serum bilirubin level estimates between 48 hours to 7 days on two different sites forehead and sternum. DOI: http://dx.doi.org/10.3126/jucms.v1i4.9567 Journal of Universal College of Medical Sciences (2013) Vol.1 No.04: 17-21
Multiple Choice Questions-Part II (Classification, Item Preparation, Analysis and Banking)
N Chaudhary,BD Bhatia,SK Mahato,KK Agrawal
Journal of Universal College of Medical Sciences , 2014, DOI: 10.3126/jucms.v2i3.11830
Abstract: No Abstract Available DOI: http://dx.doi.org/10.3126/jucms.v2i3.11830 Journal of Universal College of Medical Sciences Vol.2(3) 2014: 54-59
Severe Left Ventricular Dysfunction in Falciparum Malaria: A Case Report and Review of Literature on Cardiac Involvement in Malaria
N Chaudhary,N Verma,BD Bhatia,BK Gupta,N Kabiraj,R Lodha
Journal of Universal College of Medical Sciences , 2013, DOI: 10.3126/jucms.v1i3.8766
Abstract: Malaria is an important cause of death in both children and adults, especially in tropical countries like India1. Nearly one third cases of malaria are reported from South Asia where majority (65%) of them are from India alone 1,2. If undiagnosed and untreated promptly, falciparum malaria can be an important cause for high case fatality rate. Cerebral malaria is one of the commonest causes of death in children1. Although involvement of myocardium and cardiac failure is rare, few cases have been reported in literature. We report a 10-year old male child diagnosed as falciparum malaria with severe left ventricular dysfunction.
The immunogenicity and safety of a reduced PRP-content DTPw-HBV/Hib vaccine when administered according to the accelerated EPI schedule
Sukanta Chatterjee, Sylvan J Rego, Fulton D'Souza, BD Bhatia, Alix Collard, Sanjoy K Datta, Jeanne-Marie Jacquet
BMC Infectious Diseases , 2010, DOI: 10.1186/1471-2334-10-298
Abstract: 299 healthy infants were randomised to receive either DTPw-HBV/Hib2.5 [Kft] DTPw-HBV/Hib2.5 or DTPw-HBV/Hib according to the 6-10-14 week EPI schedule. Blood samples were analysed prior to the first dose of study vaccine and one month after the third vaccine dose for the analysis of immune responses. Solicited local and general symptoms such as pain, redness and swelling at the injection site and drowsiness and fever, unsolicited symptoms (defined as any additional adverse event) and serious adverse events (SAEs) were recorded up to 20 weeks of age.One month after the third vaccine dose, 100% of subjects receiving DTPw-HBV/Hib2.5 [Kft] or DTPw-HBV/Hib and 98.8% of subjects receiving DTPw-HBV/Hib2.5 vaccine had seroprotective levels of anti-PRP antibodies (defined as anti-PRP antibody concentration ≥0.15 μg/ml). Seroprotective antibody concentrations were attained in over 98.9% of subjects for diphtheria, tetanus and hepatitis B. The vaccine response rate to pertussis antigen was at least 97.8% in each group. Overall, the DTPw-HBV/Hib2.5 [Kft] vaccine was well tolerated in healthy infants; no SAEs were reported in any group.The DTPw-HBV/Hib2.5 [Kft] vaccine was immunogenic and well-tolerated when administered according to the EPI schedule to Indian infants.http://www.clinicaltrials.gov webcite NCT00473668Combination vaccines improve individual compliance and vaccination coverage and offer a convenient vehicle for introducing community protection against new diseases by adding antigens to an existing vaccine with high coverage [1,2]. The diphtheria-tetanus-whole cell pertussis (DTPw) is one such vaccine, with a global coverage of 81% in 2007 [3].In 1996, GlaxoSmithKline (GSK) Biologicals licensed the first combined DTPw and hepatitis B vaccine (DTPw-HBV, Tritanrix(tm)Hep B), which was shown to improve the uptake of hepatitis B vaccine in Thailand [4]. Haemophilus influenzae type b (Hib) protection was added via the monovalent vaccine, Hiberix(tm) to form DTPw-HBV/Hib.
Letter to the Editor - Chronic kidney disease in sub-Saharan Africa: Hypothesis for research demand
BD Yirsaw
Annals of African Medicine , 2012,
Abstract: No
Influence Of Early Literacy Parental Involvement On Science Achievement Of Junior Secondary School Students In Nigeria
BD Oludipe
Ethiopian Journal of Education and Sciences , 2010,
Abstract: Influence of early literacy on science achievement of Junior Secondary School students was examined in this study. The sample consisted of 360 Junior Secondary School II (JSSII) students(162 females and 198 males, mean age 13.47years, SD= 0.746) randomly selected from 12 co-educational junior secondary schools in Osun state, Nigeria. An achievement test (Integrated Science Achievement Test, ‘INSAT’) and a questionnaire (Early Literacy Parent Involvement Questionnaire, ‘ELIPIQ’) were used for data collection. The Cronbach coefficient alpha value for the questionnaire was found to be 0.62 while Reliability estimates of 0.74 was established for the achievement test. Findings revealed that: of the 360 parents involved in this study, only about 20.8% were highly involved in their children’s early literacy acquisition; parental involvement in literacy acquisition of boys was more than that of girls, though this difference was not significant; a positive relationship between parental involvement in early literacy acquisition and students’ science achievement was found and, parental involvement in children’s early literacy acquisition predicted only 0.280 (28%) of the variation of achievement in science (R2 = 0.280) and a positive but weak (r =0.183) significant relationship between parents’ educational attainment and their involvement in literacy acquisition of their children was also found. It was therefore recommended that parents should be more involved in early literacy acquisition of their children by spending time to read with them, share stories, recite rhymes, jingles, poetry, and so on.
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