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Flavonoid Contents From Some Capparidaceous Medicinal Plants of North-West Rajasthan
B.B.S. Kapoor* and Raksha Mishra
Indian Journal of Pharmaceutical and Biological Research , 2013,
Abstract: Evaluation of flavonoid contents from three selected medicinal plant species of capparidaceae familygrowing in North–Western Rajasthan was carried out. The leaves of Capparis decidua, Cleome gynandraand Cleome viscosa were analysed for flavonoid contents i.e. Quercetin and Kaempferol. Flavonoidcontents like Quercetin and Kaempferol were isolated and identified. The maximum total flavonoidcontents (1.16mg./gdw) was found in leaves of Capparis decidua while minimum (0.71mg./gdw) in leavesof Cleome viscosa.
Capparidaceous Medicinal Plants of North-West Rajasthan: Good Sources of Ascorbic Acid
B.B.S. Kapoor* and Raksha Mishra
Indian Journal of Pharmaceutical and Biological Research , 2013,
Abstract: Ascorbic acid contents of roots, shoots and fruits of three selected medicinal plants like Capparis decidua,Cleome gynandra and Cleome viscosa of family Capparidaceae have been analysed. Maximum ascorbicacid contents were found in the fruits of Capparis decidua (108.12mg/100g.d.w.) while, minimum in theroots of Cleome viscosa (62.25mg/100g.d.w).
Antimicrobial Screening of Some capparidaceous Medicinal Plants of North-West Rajasthan
B.B.S. Kapoor* and Raksha Mishra
Indian Journal of Pharmaceutical and Biological Research , 2013,
Abstract: Antimicrobial screening of ethyl ether and alcoholic extracts of leaves of three selected medicinal plantspecies of capparidaceae family growing in North–Western Rajasthan was carried out. Capparis decidua,Cleome gynandra and Cleome viscosa showed positive reactions against bacterial pathogens i.e.Staphylococcus aureus, Escherichia coli and a fungal pathogen Candida albicans.
Efficiency and duality in nonsmooth multiobjective fractional programming involving η-pseudolinear functions
Mishra S.K.,Upadhyay B.B.
Yugoslav Journal of Operations Research , 2012, DOI: 10.2298/yjor101215002m
Abstract: In this paper, we shall establish necessary and sufficient optimality conditions for a feasible solution to be efficient for a nonsmooth multiobjective fractional programming problem involving η-pseudolinear functions. Furthermore, we shall show equivalence between efficiency and proper efficiency under certain boundedness condition. We have also obtained weak and strong duality results for corresponding Mond-Weir subgradient type dual problem. These results extend some earlier results on efficiency and duality to multiobjective fractional programming problems involving η-pseudolinear and pseudolinear functions.
Study on Hexavalent Chromium Reduction by Chromium Resistant Bacterial Isolates of Sukinda Mining Area
V. Mishra,D.P. Samantaray,S.K. Dash,B.B. Mishra,R.K. Swain
Our Nature , 2010, DOI: 10.3126/on.v8i1.4313
Abstract: Rapid industrialization coupled with explosive development of chemical and mining industries has not only resulted in global deterioration of the environmental quality but also has drawn attention of scientists for an effective measure to control environmental pollution. Sukinda in the district of Jajpur, Orissa has drawn worldwide attention as one of the most polluted area with chromium due to chromate rich. In the present experiment, attempt has made to detoxify Cr (VI) by chromium resistant bacterial isolates of Sukinda mining area. Random soil and water samples were collected aseptically from four different sites of the mining area and physiochemical parameters of the samples were estimated. Out of the twelve, four chromium resistant bacterial isolates viz ., Micrococcus luteus, Pseudomonas putida, Serratia marcescens and Acinetobacter calcoaceticus tolerated hexavalent chromium beyond 500 ppm and selected for reduction. Among all, Acinetobacter calcoaceticus shown highest amount of hexavalent chromium reduction of 67.14% incubated at 30°C for 24 hr at pH 7. Then Acinetobacter calcoaceticus was selected for parametric studies and observed to exhibit highest reduction i.e., 70.53% potential at pH 8.0, temperature 30°C/24 hr. Therefore, Acinetobacter calcoaceticus may be use in the bioremediation of hexavalent chromium toxicity. DOI: 10.3126/on.v8i1.4313
Multi-response optimization of WEDM Process Parameters using the AHP and TOPSIS method
B.B. Nayak,S. S. Mahapatra
International Journal on Theoretical and Applied Research in Mechanical Engineering , 2013,
Abstract: The work presents a multi response optimization approach to determine the optimal process parameters in wire electrical discharge machining process. Experiments have been conducted using six process parameters such as discharge current, pulse duration, pulse frequency, wire speed, wire tension and dielectric flow rate each at three levels for obtaining the responses like material removal rate, roughness value of the worked surface (a measure of surface finish), and kerf. Taguchi L27 orthogonal array is used to gather information regarding the process with less number of experimental runs. Traditional Taguchi approach is insufficient to solve a multi response optimization problem. In order to overcome this limitation, a multi criteria decision making method, techniques for order preference by similarity to idealsolution (TOPSIS) is applied in the present study. In order to consider experimental uncertainty, the responses are expressed in linguistic terms rather than crisp values. The weight for each criterion (response) is obtained by analytical hierarchy process instead of using intuition and judgement of the decision maker.
Formulation and in Vitro Evaluation of Once Daily Sustained Release Formulation of Aceclofenac
S Ghosh, B.B Barik
Tropical Journal of Pharmaceutical Research , 2010,
Abstract: Purpose: The objective of the study was to develop matrix tablets for oral controlled release of aceclofenac using ethyl cellulose, guar gum and various grades of cellulose polymers. Methods: Possible drug-excipient interaction was evaluated by high performance liquid chromatography (HPLC) and Fourier infrared spectroscopy (FTIR). The tablets prepared were assessed for their physicochemical, in vitro drug release at pH1.2, 4.5, 6.8 and 7.5 and stability characteristics. Comparison with a ‘once daily’ commercial aceclofenac product was made in the in vitro studies. Results: There was no interaction between aceclofenac and the polymers used as excipients. Furthermore, the physicochemical properties of the tablets were satisfactory. The release profile of one of the formulated aceclofenac tablets (F7), which contained hydroxypropyl methyl cellulose (HPMC K4M), was statistically similar (p < 0.05) to that of the commercial aceclofenac brand in all the dissolution media. The formulated products ware stable and showed no changes in physical appearance, drug content, or dissolution pattern after storage at 40 oC /75 %RH for 6 months. Conclusion: The results indicate that it is feasible to achieve a stable ‘once daily’ sustained release aceclofenac tablet formulation by using HPMC K4M of 4000cps viscosity grade as matrix material.
A Comparative Study of the Pharmacokinetics of Conventional and Sustained-release Tablet Formulations of Aceclofenac in Healthy Male Subjects
S Ghosh, B.B Barik
Tropical Journal of Pharmaceutical Research , 2010,
Abstract: Purpose: To examine the pharmacokinetics of a formulated aceclofenac sustained release tablet formulation and determine if it is bioequivalent to a commercial brand of aceclofenac immediate release tablet (Zerodol 100 mg). Methods: Each of two groups of twelve fasting volunteers received either the reference standard (Zerodol 100 mg tablets) or the test formulation (200 mg aceclofenac) orally once, using a cross-over design with a one week wash-out period. Their blood samples were obtained at regular time intervals over 24 h and analyzed by high performance liquid chromatography (HPLC). Using the noncompartmental approach, plasma levels of aceclofenac were employed to compute their individual disposition kinetics, including peak plasma concentration (Cmax), peak time (Tmax), area under the plasma level-time curve (AUC 0-t), elimination rate constant (Kel) and elimination half life ( t1/2). Results: The Cmax values of 11043 ± 3073 ng/ml and 12301 ± 3000 ng /ml were attained in 2.58 ± 1.22 h and 1.29 ± 0.75 h for the test and reference products, respectively, while AUCO- was 45996 ± 10427 and 50253 ± 8283 ng.h/ml, respectively. At 90% confidence interval, the C max, AUC 0-t and AUC0- values of the test preparation were 96.4 - 101.3, 100.2 -101.9 and 98.5 - 99.8%, respectively, of the values for the reference. The t1/2 values were found to be 4.50 ± 1.25 and 2.20 ± 2.59 h for the reference and test products. Conclusion: On the basis of the pharmacokinetic data, it can be said that the test aceclofenac sustained release formulation and the reference product were bioequivalent in some respects. However, the test formulation exhibited a longer elimination half-life (t1/2), thus demonstrating sustained release properties, unlike the reference.
The Complementary Hankel Type Transformations Of Arbitrary Order
B.B. Waphare,S.B. Gunjal
International Journal of Analysis and Applications , 2013,
Abstract: In this paper four self-reciprocal integral transformations of Hankel type are defined. The simultaneous use of trans-formations H1,α,β and H2,α,β (which are denoted by Hα,β) allows us to solve many problems of Mathematical Physics involving the differential operator α,β= D2+4αx 1D, whereas the pair of transformations H3,α,β and H4,α,β (which we express by Hα,β) permits us to tackle those problems containing its adjoint operator, no matter what the real value of α β be. These transformations are also investigated in a space of generalized functions according to the mixed Parseval equation.
Studies on the Rheological Properties of Ogi Produced from Different Pearl Millet Varieties
S. Modu,B.B. Shehu,J. Amina,I. Nkama
Pakistan Journal of Biological Sciences , 2004,
Abstract: In the present study viscosity characteristics and pasting properties of ogi produced from six pearl (both local and improved) cultivars was studied.The ogi produced from the pearl cultivars exhibited varying degrees of rheological characteristic.The viscosity data recorded at the share rates were significantly (p < 0.05) different for the ogi`s. While the amylograph hot past viscosities for the individual ogi`s recorded significant (p < 0.05) differences in the parameters assessed. None of the ogi?samples had a characteristic peak except ogi from Gwagwa?pearl millet cultivar. The excellent stabilities exhibited by the ogi samples from LCIC-9702, SOSAT-C 88 (improved cultivars) and Zango and Ex-Borno (local cultivars) is desirable for instant ogi. There were non significant differences in the water absorption capacity of the ogi from the pearl millet varieties. SOSAT-C88andZangorecordedthehighestpercentwaterabsorptionof76and74%,respectively,while Ex-Borno was the least.
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