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Search Results: 1 - 10 of 146396 matches for " B. Prakash "
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Development and in Vitro-in Vivo Evaluation of Controlled Release Matrix Tablets of Desvenlafaxine  [PDF]
Shashidhar Reddy Dodda, Prakash Rao B
Pharmacology & Pharmacy (PP) , 2012, DOI: 10.4236/pp.2012.31003
Abstract: The objective of this investigation was to prepare extended release tablet containing matrix granules of Desvenlafaxine succinate monohydrate and to study its in vitro release and in vivo absorption. The design of dosage form was performed by choosing hydrophilic hydroxypropyl methyl cellulose (HPMC K100M), sodium carboxyl methyl cellulose (Blanose), microcrystalline cellulose (MCC) and lactose monohydrate polymers as matrix builders and polyvinyl pyrolidine (Kollidon K30) as granulating polymers. Granules were prepared by composing drug with HPMC K100M, sodium CMC, MCC and lactose monohydrate by spray drying method. Optimized formulation of Desvenlafaxine succinate monohydrate was formed by using 20% HPMC K100M, 26.6% MCC, 6.6% of sodium CMC (Blanose), 13.3% of lactose monohydrate and 5% ratio of Kollidon K30 as binder. Tablets were compressed with free flowing optimized granules of uniform drug content. This extended the release period up to 24 h in vitro study. Similarity factor and mean dissolution time were also reported to compare various dissolution profiles. The network formed by HPMC, MCC and Blanose had been coupled satisfactorily with the controlled resistance. Biopharmaceutical study of this optimized dosage form in rabbit model showed 24 h prolonged drug release in vivo. A close correlation (R2 = 0.9833) was established between the in vitro release and the in vivo absorption of drug. The results suggested that wet granulation with spray dried technique, is a suitable method to formulate sustained release Desvenlafaxine succinate monohydrate and it can Perform therapeutically better than conventional immediate release dosage form.
Modified Vegetable Oil Based Additives as a Future Polymeric Material—Review  [PDF]
Nikesh B. Samarth, Prakash A. Mahanwar
Open Journal of Organic Polymer Materials (OJOPM) , 2015, DOI: 10.4236/ojopm.2015.51001
Abstract: Polymeric materials from renewable resources have attracted a lot of attention in recent years. The development and utilization of vegetable oils for polymeric materials are currently in the spotlight of the polymer and chemical industry, as they are the largest renewable platform due to their universal wide availability, ingrained biodegradability, low cost, and excellent environmental aspects (i.e., low ecotoxicity and low toxicity toward humans). These excellent natural characteristics are now being taken advantage of in research and development, with vegetable oil derived polymers/polymeric materials/composites being used in numerous applications including paints and coatings, adhesives, and nanocomposites. The aim of this review paper is to give a fundamental description of the various vegetable oil applications in polymer materials and its recent developments. Particular emphasis will be placed on study and main application of triglyceride based additive for polymer and to give the reader an insight into the main developments is discussed.
Variant Inferior Root of Ansa Cervicalis
Babu,B. Prakash;
International Journal of Morphology , 2011, DOI: 10.4067/S0717-95022011000100040
Abstract: ansa cervicalis is a loop of nerves found in the anterior wall of the carotid sheath in the carotid triangle of neck innervating infrahyoid muscles. its superior root has fibres from the first cervical nerve that leaves the hypoglossal nerve and joins the inferior root formed by the branches from the second and third cervical nerves. the two roots join to form ansa cervicalis. the ansa cervicalis nerve formation is relatively complex, as its course and location along the great vessels of the neck vary. in the present case on the left side of an adult male cadaver the inferior root was absent and the contributions from c2 and c3 were joining independently with the superior root of ansa to form ansa cervicalis. however no such variation was found in the ansa cervicalis formation on the right side.
Variant Inferior Root of Ansa Cervicalis Variación de la Raíz Inferior del Asa Cervical
B. Prakash Babu
International Journal of Morphology , 2011,
Abstract: Ansa cervicalis is a loop of nerves found in the anterior wall of the carotid sheath in the carotid triangle of neck innervating infrahyoid muscles. Its superior root has fibres from the first cervical nerve that leaves the hypoglossal nerve and joins the inferior root formed by the branches from the second and third cervical nerves. The two roots join to form ansa cervicalis. The ansa cervicalis nerve formation is relatively complex, as its course and location along the great vessels of the neck vary. In the present case on the left side of an adult male cadaver the inferior root was absent and the contributions from C2 and C3 were joining independently with the superior root of ansa to form ansa cervicalis. However no such variation was found in the ansa cervicalis formation on the right side. El asa cervical es un loop de nervios que se encuentra en la pared anterior de la vaina carotídea, en el triángulo carotídeo del cuello, que inerva los músculos infrahioideos. Su raíz superior tiene fibras del primer nervio cervical que sale del nervio hipogloso y se une a la raíz inferior formada por las ramas de los nervios cervicales segundo y tercero. Las dos raíces se unen para formar el asa cervical. La formación del asa cervical del nervio es relativamente compleja, ya que su curso y ubicación varía a lo largo de los grandes vasos del cuello. En el lado izquierdo del cuello de un cadáver adulto de sexo masculino, la raíz inferior del asa cervical estaba ausente y las contribuciones de los ramos de C2 y C3 se unieron, de forma independiente, con la raíz superior del asa y así formar el loop.
An Experimental Study on Mechanical and Fracture Behavior of Phosphoric Iron  [PDF]
A. K. Vishnoia, B.K. Mishra, S. Prakash
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2010, DOI: 10.4236/jmmce.2010.912079
Abstract: Phosphoric iron of two different phosphorus content, namely P1 (Fe-0.30P-0.226C), P2 (Fe-0.11P-.028C) were first prepared by ingot casting route. The ingot were soaked and forged at 1150℃. The microstructures of the phosphoric iron and its relevant mechanical properties such as hardness and tensile properties have been characterized. J-R curves of the material have been determined at room temperature. Fracture behaviour under tearing load has been studied through fracture toughness tests on phosphoric iron using Compact Tension (CT) specimens of Width (W) =50 mm and thickness (B) =12.5mm. J-R curves were obtained from specimens precracked to a/W = 0.5 .The single specimen unloading compliance method have been used for generating J-R curves.
Changes in Plasma GH, LH and Progesterone and Blood Metabolites Following Long-term Exogenous Somatoliberin Administration in Growing Buffaloes (Bubalus bubalis)
Mohan Mondal,B. S. Prakash
Journal of Animal and Veterinary Advances , 2012,
Abstract: To investigate the effects of long-term somatoliberin on changes in plasma GH, LH and progesterone and blood metabolites in growing female buffalo calves, twelve calves within the age group of 6 to 8 months of age were divided into two groups (treatment and control groups) of six each in such a way that their mean body weight did not differ (P>0.01) and were fed as per Kearl standard (1982) for growing buffaloes. Treatment group buffaloes were administered i.v. with synthetic bGRF [ somatoliberin; bGRF (1-44)-NH2 ] @ 10Fg/100 Kg. body weight at fortnight interval till 18 injections were completed (9 months). Blood samples were collected at fifteen days interval one month prior to and two month post-treatment for estimation of plasma GH, LH and progesterone and blood metabolites viz. non-esterified fatty acids (NEFA), alpha amino nitrogen and glucose. During pre-treatment period, plasma GH, LH and progesterone and blood metabolites did not differ (P>0.05) between the groups. Post-somatoliberin administration at the end of first month, the plasma GH and LH showed a higher trend (P<0.001) in somatoliberin treated buffaloes over untreated controls and this trend continued even in post-treatment period. Increasing trend (P<0.01) of plasma LH with advancing age of the calves was also recorded in both the groups. Unlike untreated controls, a definite up and rise trend of plasma progesterone was recorded in somatoliberin treated group during treatment period. Plasma NEFA, alpha amino nitrogen and glucose were found to be higher (P<0.05) in treatment than control group. Results indicate that long-term exogenous somatoliberin administration sustained a higher level of plasma GH even after cessation of treatment without showing any sign of refractoriness in this species. The buffaloes treated with somatoliberin may approach puberty earlier as they would reach the >critical= body mass earlier, is also reflected by higher plasma progesterone and LH concentrations. However, detailed studies are required to ascertain the hypothesis.
Control of mango anthracnose by hot water and fungicides treatment
OM PRAKASH and B. K. PANDEY
Indian Phytopathology , 2012,
Abstract: Following harvest, mango (cv. Dashehari) fruits were treated with hot water at 52℃ for 5, 15 and 30 min alone and in combination with fungicides to control postharvest anthracnose (Colletotrichum gloeosporioides [Glomerella cingulata]) disease. Hotwater (52℃) alone for 30 min was very effective in controlling the disease. Treated fruits could be stored at 12?for up to 26 days (21 days at 12?+ 5 days at ambient temperature for ripening). However, the duration of hot water treatment could be reduced to 15 min by supplementing with carbendazim or thiophanate-methyl (each @ 0.1%). Hot water (52?for 15 min) together with carbendazim treated fruits could be stored for 26 days at 12?without any anthracnose infection, while with thiophanate-methylfruits could be stored for only 19 days at 12? Fungicides applied at ambient temperature did not control anthracnose. Hot water treatments did not show any adverse effect on fruit ripening.
Epidemiology of disability in incident leprosy patients at supervisory urban leprosy unit of Nagpur city
L B Chavan, Prakash Patel
National Journal of Community Medicine , 2011,
Abstract: Leprosy is a chronic infectious disease caused by Mycobacterium Leprae, affecting mainly peripheral nerves and skin. Disabilities and deformities are major concerns as it triggers social, economic and psychosocial problems of leprosy patients. In the study, 105 incident leprosy patients registered in a randomly selected Supervisory Urban Leprosy Unit during year 2004-05 were interviewed. Disability was graded as per WHO-2 point scale. There were 52 male and 53 female with median age of 26 years. The WHO grade -II disability was 12.38 % and it was significantly higher among manual workers and housewives (76.92%, P<0.05). Hands and feet disabilities were found in 38.10 % while nobody had eye related disability. Subjects with delayed diagnosis beyond 12 months had significantly higher grade-2 disabilities than diagnosed earlier (P<0.05). Disability rate was also higher in Multi-Bacillary leprosy patients (P<0.001). Ulcer was the most common type of grade-II deformity (61.54 %) which was significantly higher in females (P<0.05). Prevalence of disability was found higher in study area than national average. Awareness about Prevention Of Deformities (POD), early diagnosis (<12 months) and treatment are recommended to avert visible deformities and hence social stigma in leprosy patients.
Anterior Crossbite Correction in Early Mixed Dentition Period Using Catlan's Appliance: A Case Report
Prashanth Prakash,B. H. Durgesh
ISRN Dentistry , 2011, DOI: 10.5402/2011/298931
Abstract:
Quantum Alternation: Prospects and Problems
Costin B?descu,Prakash Panangaden
Computer Science , 2015, DOI: 10.4204/EPTCS.195.3
Abstract: We propose a notion of quantum control in a quantum programming language which permits the superposition of finitely many quantum operations without performing a measurement. This notion takes the form of a conditional construct similar to the IF statement in classical programming languages. We show that adding such a quantum IF statement to the QPL programming language simplifies the presentation of several quantum algorithms. This motivates the possibility of extending the denotational semantics of QPL to include this form of quantum alternation. We give a denotational semantics for this extension of QPL based on Kraus decompositions rather than on superoperators. Finally, we clarify the relation between quantum alternation and recursion, and discuss the possibility of lifting the semantics defined by Kraus operators to the superoperator semantics defined by Selinger.
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