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Response of lettuce to Cd-enriched water and irrigation frequencies
A Azizian, S Amin, M Maftoun, Y Emam, M Noshadi
African Journal of Environmental Science and Technology , 2011,
Abstract: This pot experiment was an attempt to investigate a broad response of lettuce to different cadmium (Cd) levels of irrigation water (0, 5, 10 and 20 mg l-1) under different irrigation intervals (1, 2 and 4 days). The results showed that increased level of soil Cd through irrigation eventually decreased the yield of lettuce in all cases; however, in some cases yield was increased with lower doses of Cd application. No injury symptoms were observed other than plant height and yield reduction. Shoot dry weight proved to be the most sensitive parameters to the cadmium, especially under water stress conditions. The results also showed that the concentrations of nutrient elements in lettuce shoot were suppressed by water stress. The presence of cadmium in irrigation water did not significantly affect the absorption of nutrient elements by plants except for Fe. Shoot Cd concentration and its uptake decreased with increasing irrigation frequencies and the reverse trend occurred with increasing Cd levels of irrigation water. However, the values were higher than recommended guideline in all conditions. Also, shoot Cd content showed a significant positive correlation with the final accumulated Cd concentration of soil and was expressed by a plateau model under the dry irrigation regime and linear models at other irrigation intervals. Overall, shoot Cd concentration was predicted by using a simple linear regression model regardless of evapotranspiration and transpiration rate of plant.
Protective Effect of Dendrosomal Curcumin Combination on Colon Cancer in Rat
Sarbolouki MN,Alizadeh AM,Khaniki M,Azizian S
Tehran University Medical Journal , 2012,
Abstract: Background: Cancer is a multistep process that develops very rapidly after its onset. Previous studies have confirmed antitumor effects of curcumin (1,7-bis (4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; diferuloylmethane) that can potentially prevent colon cancer development with low side-effects. Different methods have been performed to increase the efficiency and effectiveness of curcumin among which dendrosome, a nanoparticle created by Sarbolouki et al. was used in this study. The present study was undertaken to evaluate the effects of dendrosomal curcumin on rat colon cancer. Methods: In this study which was performed in Cancer Research Center of Tehran University of Medical Sciences in 2010 year, forty rats were equally divided into control, curcumin and curcumin-dendrosome groups. Animals received azoxymethane (15 mg/kg s.c.), a carcinogen, once a week for two weeks. Curcumin (0.2%) and curcumin-dendrosome were administered to the respective animals 2 weeks before the first and 14 weeks after the last azoxymethane injections. Eventually, colorectal specimens from tumoral and adjacent non-tumoral mucosal tissues were fixed in 10% formaldehyde, and passaged and embedded in paraffin. Histopathological and immunohistochemical studies were performed on the specimens. Results: The mean number of lesions, nuclear/cytoplasmic ratio, epithelial stratification, loss of nuclear polarity, goblet depletion, structural abnormality and beta-catenin expression were higher in the control group compared to curcumin and curcumin-dendrosome groups. These parameters had significantly decreased in the dendrosomal curcumin group (P<0.05). Conclusion: The present study shows that dendrosome can be used as a suitable nanoparticle to increase curcumin efficiency in the prevention or treatment of colon cancer.
Servey Impact of Activated Alumina in Fluoride Concentration Peresent in Water and Appointment Adsorption Isotherm and Kinetics
M.T Samadi,R Nourozi,S Azizian,Y Dadban Shahamat
Iranian Journal of Health and Environment , 2009,
Abstract: Backgrounds and Objectives: Determination of Fluoride in drinking water has received increasing interest, duo to its beneifical and detrimental effects on health. The aim of this research is investigation of Effect of activated alumina in fluoride concentration reduction in drinking water."nMaterials and Methods: Expriment in batch system and with change effective parameters such as pH(5, 7,9), equilibration time (30, 60, 90, 120 minute), initial fluoride concentration(1.4, 2, 2.4 mg/l) and activated Alumina dosage (0.1, 0.2, 0.3 gr/l) was investigated. Also found data of this research were fited with Langmuir and Freundlich models, kinetic data with pseudo- first order, pseudo- second order and modifited pseudo- first order models."nResults: The results showed that with increasing of pH of solution, removal efficiency was decreased and optimum pH was found to be in the range of 5 to 7. Also removal efficiency of fluoride was increased with increasing of adsorbent dosage and decreasing of initial concentration of fluoride. Adsorption isotherm data show that the fluoride sorption followed the Langmuir model (r2=0.98). Kinetics of sorption of fluoride onto Activated alumina was well described by pseudo- second order model."nConclusion: The concentration of Activated Alumina had significant effect on the reduction of fluoride ions concentration in water.The higher fluoride removals were observed for batch experiments at pH=5 because no free fluoride ion is present in the solutions, and it could be casued by electrostatic interactions between the surface of alumina and the dominant fluoride species in solution The kinetic model can adequately describe the removal behaviors of fluoride ion by alumina adsorption in the batch system.
CorePLAN Radiotherapy Planning System Based on PACS
Morteza Bakhtiary,Amirreza Azizian
Iranian Journal of Radiology , 2007,
Abstract: Accurate and precision tumor treatment in radiotherapy is one of the critical problems for cancer therapy. Before foundation of DICOM, planning done through inaccurate and 2D methods using simple images that are contoured using a digitizer device on hard copy images of CT or X-ray. Body, tumor and normal contours made by user. After introducing DICOM, medical physicists and oncologists try to plan based on DICOM files which acquired, archived and delivered by PACS."nCorePLAN is a representative product of Seoul C&J, Inc. for treatment planning based on PACS. This product is a convenient and comprehensive radiation therapy planning system that supports 3D conformal treatment, multi-plan, IMRT (Intensity Modulated Radiation Therapy) with useful intelligent functions and automatic registration suite. CorePLAN provides accurate dose calculations based on the collapsed cone convolution method, which is proven by the KFDA. The accuracy of its algorithms was confirmed through numerous clinical tests and achievement of treating over 700 patients. "nCorePLAN demonstrates excellent accuracy, and its high-speed calculation is as fast as that of 2D algorithms. This is a result of the implementation of new technologies and rigorous optimization based on PACS."nSome CorePLAN features are:"n-Automatically detecting and contouring the body, contouring desired regions easily with a single click."n-Digitizer for making Images that is contoured using a digitizer device."n-Film Scanner to producing digitalized images through a film scanner device. "n-DICOM QNR that combines with other DICOM-compatible applications is done through DICOM query and retrieval methods. "n-DICOM 3.0 standard which support DICOM-RT standard."n-DICOM Server that used while linked with PACS system and others. "n-CoreFusion which is a convenient and accurate registration system that supports every important medical modality (CT, MR and PET) for excellent tumor contouring and visualization for treatment follow up, which supports automatic, marker-based and manual registration.
H2TPP Organocatalysis in Mild and Highly Regioselective Ring Opening of Epoxides to Halo Alcohols by Means of Halogen Elements
Parviz Torabi,Javad Azizian,Shahab Zomorodbakhsh
Molecules , 2012, DOI: 10.3390/molecules17055508
Abstract: We found that elemental iodine and bromine are converted to trihalide nucleophiles (triiodine and tribromide anion, respectively) in the presence of catalytic amounts of meso-tetraphenylporphyrins (H2TPP). Therefore a highly regioselective method for the synthesis of b-haloalcohols through direct ring opening of epoxides with elemental iodine and bromine in the presence of H2TPPs as new catalysts is described. At room temperature a series of epoxide derivatives were converted into the corresponding halohydrins resulting from an attack of trihalide species anion atoms at the less substituted carbon atom. This method occurs under neutral and mild conditions with high yields in various aprotic solvents, even when sensitive functional groups are present.
A Comprehensive Review and Analysis of Maturity Assessment Approaches for Improved Decision Support to Achieve Efficient Defense Acquisition
Nazanin Azizian,Shahram Sarkani,Thomas Mazzuchi
Lecture Notes in Engineering and Computer Science , 2009,
Abstract:
Assessment of Cost Benefits of Establishing Picture Archiving and Communication Systems (PACS) in Clinical Centers Using Economic Models
Mahdie Jajroudi,Amir Reza Azizian,Hassan Ghantaati
Iranian Journal of Radiology , 2010,
Abstract: Clinical and healthcare systems are continuously under a progressive pressure of improving patients' treatment qualities and increasing their system's efficacy. Accepting new technologies by healthcare systems occurs with a view to control costs and im-proves the quality of services. The radiology department is one of the most important parts of healthcare and clinical organizations and using new technology leads to its forward improvements."nThe target goal of powerful PACS is to improve the quality of treatment. The better the quality of treatment and physician satisfaction, the higher the patient cure as well as the less patient return which is aquired by increasing the effectiveness of treatment and diagnostic systems, decreasing costs and increment of communications between treatment and diagnostic parts."nDespite numerous benefits of PACS for healthcare centers, most departments do not have established PACS or are using these systems in limited settings. In addition, it is always concerning that these systems do not have economic evaluation and capital inflow as well as the fact that the interests are not gained in return for high costs of installing and maintenance."nThe purpose of this article was to show how PACS leads to fewer expenses compared with those of film-less systems. Two direct and indirect methods have been used for analyzing the expenses. In the direct method, conventional financial schemes (i.e. net present value [NPV] and internal rate of return [IRR]) are applied and it is highlighted that changing workflow condition and system efficiency could decrease the costs in the indirect method.
Violence Against Women: A Study of Underlying Factors in Tehran Forensic Center 1380
R Azizian,B Saroukhani,M Mahmodi
Journal of School of Public Health and Institute of Public Health Research , 2004,
Abstract: Across the world, violence against women is a major threat to their physical and mental well-being. This violation of the most fundamental human rights usually takes the form of family or domestic violence. According to global statistics, the rates of death and disability resulting from violence to women of reproductive is comparable to those from cancers and more than those due to car accidents and infectious diseases. Data for this cross-sectional study were collected from women referring to Tehran Forensic Center, with a view to obtaining a realistic picture of violence to women. The women in this study had presented with wounds and injuries inflicted by their husbands. These women had been referred to the Center by family courts to complete legal formalities concerning injury diagnosis and duration of treatment. Data were gathered on 120 subjects randomly selected women who completed questionnaires and interviews. The main factors underlying family violence were examined from five different aspects: behavioral and educational problems (79.2%), financial strain (54.2%), interference by the husband’s family (39.2%), sexual problems (13.3%), and differences in culture and social class (10%). However, many women declared that several factors were contributing simultaneously to the problem of violence. Factors found to have an accelerating or interfering role included the woman’s age and the couple’s education level.
Laryngeal angioleiomyoma: A case report of 52-year-old female  [PDF]
Ahmad Rezaee, Leili Ebrahimi, Alireza Sadeghipour, Behzad Sarvar Azimzadeh, Amir Reza Azizian
Case Reports in Clinical Medicine (CRCM) , 2013, DOI: 10.4236/crcm.2013.21006
Abstract:

Introduction: Laryngeal angioleiomyoma is a rare benign tumor of larynx with vascular origin. We report a case of laryngeal angioleiomyoma in a 52-year-old female. Case presentation: A 52- year-old Caucasian female was referred to our institute with a chief compliant of severe midnight snoring. Her symptoms were progressive and began from two years ago. There was no history of hoarseness and laryngeal pain. The patient underwent a laryngoscopic examination and a large mass was seen on the left aryepiglotic fold. Surface of lesion was smooth and covered by laryngeal mucosa with no ulcer. There was a rapid enhancing mass on left aryepiglotic fold with bulging into the left piriformis sinus in contrast-enhanced computed tomography. The tumor was complicated by profuse bleeding after biopsy which was not controlled by conventional approaches. The patient was then administered a general anesthesia and the tumor was completely removed via laryngosurgery accompanied by left superior thyroid artery ligation. The specimen was histopathologically compatible with laryngeal angioleiomyoma. Conclusion: Angioleiomyoma of larynx is of benign nature and rarely recurs. However, it can be complicated by profuse bleeding on biopsy and contrast-medium imaging should be considered before surgical intervention to diagnose the tumor properly and prevent life-threatening complications.

Functionalization of carboxylated multiwall nanotubes with imidazole derivatives and their toxicity investigations
Javad Azizian, Hasan Tahermansouri, Esmaeil Biazar, et al
International Journal of Nanomedicine , 2010, DOI: http://dx.doi.org/10.2147/IJN.S13629
Abstract: nctionalization of carboxylated multiwall nanotubes with imidazole derivatives and their toxicity investigations Original Research (5772) Total Article Views Authors: Javad Azizian, Hasan Tahermansouri, Esmaeil Biazar, et al Published Date November 2010 Volume 2010:5 Pages 907 - 914 DOI: http://dx.doi.org/10.2147/IJN.S13629 Javad Azizian1, Hasan Tahermansouri1, Esmaeil Biazar2, Saeed Heidari3, Davood Chobfrosh Khoei1 1Department of Chemistry, Science and Research branch, Islamic Azad University, Ponak, Tehran, Iran; 2Young researchers club – Islamic Azad University, Tonekabon Branch, Iran; 3Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshty University of Medical Sciences,Tehran, Iran Abstract: Imidazoles and their derivatives are compounds with chemotherapeutic applications. In this study, we investigated the chemical functionalization of carboxylated multiwalled carbon nanotubes (MWNT–COOH) by 1,2-phenylendiamine. Multiwalled nanotube (MWNT)–benzimidazole was obtained by an MWNT–amide reaction with POCl3 after 72 hours, which was confirmed by Fourier transform infrared, scanning electron microscopy, thermal gravimetric analysis, and elemental analysis. These functionalizations were chosen due to -NH2 and NHCO active sites in MWNT–amide for future application. Toxicity assays with fibroblast cells and MTT test for measurement of viable cell numbers were also performed. Cellular results did not show any toxicity change in modified samples from that of the reference samples.
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