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Investigating Catalase and Carbonic Anhydrase Enzyme Activities and Levels of Certain Trace Elements and Heavy Metals in Patients with Primary and Metastatic Hepatic Carcinoma  [PDF]
Ayse Arslan, Halit Demir, Harun Arslan
Journal of Cancer Therapy (JCT) , 2013, DOI: 10.4236/jct.2013.48163

Hepatocellular carcinoma (HCC) is among most common terminal cancer types in the world. Primary etiological factors include cirrhosis, hepatitis, aflatoxin and alcohol. The current study was conducted to determine cytosolic erythrocyte carbonic anhydrase and catalase enzyme activities and levels of some trace elements. For this purpose, 40 patients with primary and metastatic hepatic cancer and 29 healthy volunteers enrolled to the study. Catalase and carbonic anhydrase enzyme activities and serum trace element levels were measured in patient and control groups. In the current study, serum copper, magnesium, manganese and zinc levels were lower in the primary and metastatic hepatic cancer group in comparison with the control group (P < 0.05). In contrast, serum iron, cobalt, cadmium and lead levels were higher in the patient relative to the control group (P < 0.05). In comparison with the control group, the catalase level was lower in primary and metastatic cancer group, while the carbonic anhydrase level was higher in the cancer group (P < 0.05). Changes in levels of trace elements and anti-oxidant enzymes may be the factors which influence the development and progression of liver cancer. The carbonic anhydrase enzyme can be a useful indicator in the diagnosis of cancer. However, this issue warrants further investigation.

Evaluation of Lipid Peroxidation and Some Antioxidant Activities in Patients with Primary and Metastatic Liver Cancer  [PDF]
Ayse Arslan, Halit Demir, M. Fatih Ozbay, Harun Arslan
Journal of Cancer Therapy (JCT) , 2014, DOI: 10.4236/jct.2014.52024

Abstract: HCC is the 6th most common cancer in the world. The main risk factors associated with HCC are hepatitis B (HBV) and hepatitis C viral infections and other factors that play a role in HCC development, include aflatoxin B1 (AFB1) cigarette smoking, and chronic inflammation. The aim of this study is to investigate lipid peroxidation and some antioxidant enzyme activities in patients with primary and metastatic liver cancer. For this purpose, 25 primary and metastatic liver cancer patients and 15 healthy controls were included in the study. In blood samples taken from the patient and control groups, the main product of lipid peroxidation MDA and SOD, GSH, GPx activity levels were examined. In result of study serum MDA level is higher and erythrocyte SOD, GSH, and GPx activities were found to be significantly lower in the patient group compared with the control group (p < 0.05). As a result, liver cancer is associated with oxidative stress and antioxidant system weakens, which is an important indicator of oxidative stress, lipid peroxidation levels increased and promotes the tissue damage.

Esneyebilir bir protez kaide rezin ile hareketli b lümlü protezlerin yap m : vaka sunumu
Koray Soygun,Hakan Demir,Giray Bolayir,Ayse Kubra Demir
Cumhuriyet Dental Journal , 2011, DOI: 10.7126/cdj.2012.1132
Abstract: Aesthetic considerations in dental treatment are directly related to the sentiments and opinions of the patient. Aesthetics has been a crucial factor for fixed rehabilitations, but nowadays removable partial dentures also show great interest in satisfying the aesthetic requirements. Tooth selection, teeth arrangement, and the compatibility of the artificial tooth with face structure are known to affect aesthetics in removable partial dentures. In addition to these, poor design of clasp systems can be the major impairment factors in structural components of these dentures. Although development of precision attachments, and the clasp systems, it is unable to obtain satisfying aesthetic with removable partial dentures. In this study, we present a case report that describes the rehabilitation of a patient with a polyamide (PA6.6) denture base resin in order to remedy both the functional and aesthetic considerations. ZET Di hekimli inde estetik gereksinimler hastalar n duygu ve dü ünceleriyle direk ilgilidir. Estetik yakla mlar protetik tedavide zellikle sabit rehabilitasyonlar i in ncelik ta sa da bugün hareketli b lümlü protezler i in de ayn derecede nem olu turmaktad r. Hareketli b lümlü protezlerde estetin sa lanmas nda di se imi, di dizimi, yapay di lerin yüz ekliyle uygunlu u gibi fakt rlerin etkili oldu u bilinmektedir. Bununla birlikte bu protezlerin yap sal unsurlar aras nda esteti i olumsuz y nde etkileyen en nemlisi kro e sistemleridir. Estetik gereksinimleri kar lamas a s ndan bir ok kro e sistemi, hassas tutucular geli tirilmesine kar n baz vakalarda bu sistemler yeterli olamamaktad r. Bu al mada fonksiyonel ve estetik gereksinimleri kar lamak amac yla geli tirilmi poliamid (PA 6.6) protez kaide rezin ile yap lan vakam z sunmay ama lad k. Anahtar Kelimeler: Hareketli b lümlü protez, estetik, kro e, poliamid 6.6
An Acute Edematous Pancreatitis Case caused by Probably Hypertriglyceridemia: Case Report
Ertugrul Kayacetin,Ruhusen Kutlu,Ayse Demir
TAF Preventive Medicine Bulletin , 2010,
Abstract: Hypertriglyceridemia is one of the non-biliary, eluding important causes of acute pancreatitis. Currently, there is no standardized protocol to treat these patients. We presented a case with acute edematous pancreatitis caused by hypertriglyceridemia in this case report. The patient, then, complicated with a pseudocyst in the pancreas and bilateral pleural effusion. We aimed to present this case with acute pancreatitis due to the probable hypertriglyceridemia and to show how one can handle these complications. [TAF Prev Med Bull 2010; 9(3): 263-268]
Factors of Acceptance for Mobile Learning in Corporate Settings: An Empirical Investigation in Banking Industry  [PDF]
Ayse Kok
Intelligent Information Management (IIM) , 2013, DOI: 10.4236/iim.2013.55015
Abstract: Due to the proliferation of mobile technology and devices like smartphones and tablet PCs into our daily lives, m-learning attracts also more attention in professional training in enterprises. Derived from these statements, this research paper is focused on the following question: what are acceptance factors for m-learning (mobile learning) in the organizational setting? The paper analyzes a real experience in m-learning for training the banking personnel in an international banking institution in Turkey. For this purpose, a mobile virtual learning environment called as mFOR@ was developed and implemented, which was designed to support the training and development process for employees using Pocket PCs. The participants of the training activity (13 professionals) evaluated the m-learning experience via a semi-structured interview; all the content and interactions within mFOR@ were analyzed via content analysis. As a basis for a successful implementation in professional training in enterprises, the acceptance by decision makers and the learners is critical. That is the reason why I present a qualitative analysis of acceptance and the perceived value of m-learning in a corporate setting.
Behind the Scenes with a Video Training Platform: The Challenges of Researching the Provision of Open Educational Resources  [PDF]
Ayse Kok
Advances in Internet of Things (AIT) , 2013, DOI: 10.4236/ait.2013.34009

Video training platforms are now being implemented on a large scale in organizations. In this paper, I look at a video training platform including open educational resources available for many employees with varying patterns and motivations for use. This has provided me with a research challenge to find methods that help other practitioners in the field understand and explain such initiatives. I describe ways to model the research and identify where pressures and contradictions can be found, drawing on a reflective view of my own practice in performing the research. Open educational resources are defined as technology-enabled educational resources that are openly available for consultation, use and adaptation by users for non-commercial purposes [1]. The bank subject to this case study has been the first organisation in Turkey that provided open educational resources for all its employees. The video platform (called “For @ Tube”) provides users with over 100 video lectures drawn from reputable universities around the world including Yale and Harvard. Other learning tools such as discussion forums, blogs and traditional e-learning courses have been made available to the users on the e-learning platform called “For @” since 2006. In this paper, I aim to introduce the new video training platform (“For @ Tube”) and outline some of the main research issues surrounding such an

Evaluation of Nutritional Habits of Obese Children in Toddler Period and Their Families  [PDF]
Senay Cetinkaya, Ayse Gurol
Open Journal of Pediatrics (OJPed) , 2018, DOI: 10.4236/ojped.2018.82019
Abstract: Toddler period is the period that nutritional habits are learnt. This research is a semi-analytical field research that was performed in doctors’ offices 1, 6 and 7 in the provincial center of Konya with the purpose of determining the socio-demographic characteristics of obese pre-school children and their families who volunteered to participate in the research. The cosmos of the research consists of 22 village clinics in Konya provincial center. Obese Cosmos consists of obese children between 1 - 3 years of age and their families who applied to outpatient clinics of the Doctors’ Offices numbered 1, 6 and 7, which were selected with cluster sampling method, for vaccination and who accepted to participate in the research. Data were collected between 01 January 2005 and 31 March 2005 by using a questionnaire and a form of anthropometric measures to enter the measures of height, weight, thickness of skin folds, and waist and hip size. The difference between the increase of weight of the mother during pregnancy and the non-categorized RW outputs of the child in birth was found to be statistically significant (p < 0.05). Variation analysis was performed in order to check whether or not there was a difference between the period of breastfeeding and Standart Deviation Score (SDS) and Relative Weight (RW) values and it was found to be significant (p < 0.05). No statically significant relationship was found between the time child spends watching TV daily and SDS and RW values of the child (p > 0.05). Although there was found no statically significant relationship between the daily play hours of the child and SDS (p > 0.05), there was a significant relationship between RW (p < 0.05). It is important that the parents should spend more time playing with their children and increasing the play time. Informing booklets have been prepared and given to parents with the purpose of training.
Protection against Diarrhea Associated with Giardia intestinalis Is Lost with Multi-Nutrient Supplementation: A Study in Tanzanian Children
Jacobien Veenemans,Theo Mank,Maarten Ottenhof,Amrish Baidjoe,Erasto V. Mbugi,Ayse Y. Demir,Jos P. M. Wielders,Huub F. J. Savelkoul,Hans Verhoef
PLOS Neglected Tropical Diseases , 2011, DOI: 10.1371/journal.pntd.0001158
Abstract: Background Asymptomatic carriage of Giardia intestinalis is highly prevalent among children in developing countries, and evidence regarding its role as a diarrhea-causing agent in these settings is controversial. Impaired linear growth and cognition have been associated with giardiasis, presumably mediated by malabsorption of nutrients. In a prospective cohort study, we aim to compare diarrhea rates in pre-school children with and without Giardia infection. Because the study was conducted in the context of an intervention trial assessing the effects of multi-nutrients on morbidity, we also assessed how supplementation influenced the relationship between Giardia and diarrhoea rates, and to what extent Giardia modifies the intervention effect on nutritional status. Methods and Findings Data were collected in the context of a randomized placebo-controlled efficacy trial with 2×2 factorial design assessing the effects of zinc and/or multi-micronutrients on morbidity (n = 612; height-for-age z-score <?1.5 SD). Outcomes measures were episodes of diarrhea (any reported, or with ≥3 stools in the last 24 h) and fever without localizing signs, as detected with health-facility based surveillance. Giardia was detected in stool by enzyme-linked immunosorbent assay. Among children who did not receive multi-nutrients, asymptomatic Giardia infection at baseline was associated with a substantial reduction in the rate of diarrhea (HR 0.32; 0.15–0.66) and fever without localizing signs (HR 0.56; 0.36–0.87), whereas no such effect was observed among children who received multi-nutrients (p-values for interaction 0.03 for both outcomes). This interaction was independent of age, HAZ-scores and distance to the research dispensary. There was no evidence that Giardia modified the intervention effect on nutritional status. Conclusion Although causality of the Giardia-associated reduction in morbidity cannot be established, multi-nutrient supplementation results in a loss of this protection and thus seems to influence the proliferation or virulence of Giardia or associated intestinal pathogens.
Non-commutative geometry and irreversibility
Ayse Erzan,Ayse Gorbon
Physics , 1997, DOI: 10.1007/s100510050159
Abstract: A kinetics built upon $q$-calculus, the calculus of discrete dilatations, is shown to describe diffusion on a hierarchical lattice. The only observable on this ultrametric space is the "quasi-position" whose eigenvalues are the levels of the hierarchy, corresponding to the volume ofphase space available to the system at any given time. Motion along the lattice of quasi-positions is irreversible.
Pre-Service Primary Teachers’ Attitudes towards Mathematics in an Australian University  [PDF]
Dilshara Hill, Ayse Aysin Bilgin
Creative Education (CE) , 2018, DOI: 10.4236/ce.2018.94042
Abstract: Pre-service primary teachers are important people to shape future generations, as they will be the first face of mathematics a young child meets when he/she starts school. Since numerical literacy is becoming as important as literacy itself due to ease of data collection and ease of analysis of the data, it is important to educate the future generation and their teachers to be as effective as possible in their abilities to learn/teach mathematics. The research on pre-service teachers’ mathematical anxiety and their attitudes towards mathematics show that the pre-service teacher typically has high levels of maths anxiety and that their attitude to mathematics makes a big difference to their learning during their studies at the university and then teaching mathematics to their young students. The purpose of this study was to investigate the relationship between previous (i.e. high school) mathematics study and attitudes toward mathematics. Our study showed that a high percentage of participants who studied mathematics in their final year at high school had a somewhat positive attitude toward mathematics.
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