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Search Results: 1 - 10 of 30866 matches for " Aurélie Robert "
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Functional design method for improving safety and ergonomics of mechanical products  [PDF]
Aurélie Robert, Sébastien Roth, Dominique Chamoret, Xiu Tian Yan, Francois Peyraut, Samuel Gomes
Journal of Biomedical Science and Engineering (JBiSE) , 2012, DOI: 10.4236/jbise.2012.58058
Abstract: In order to help companies to improve their competetiveness, it is important to develop new design methodologies. In this framework, a Functional And Robust Design (FARD) methodology dedicated to routine design of “highly productive” modular product ranges is proposed including principles of functional analysis, Design For Assembly (DFA), and techniques of modelling and simulation for ergonomics consideration. This paper focuses on the application of this original method applied to mechanical vibration and ergonomics problems of a scraper. Including biomechanical aspect in the design methodology, it is possible to identify the impact of a vibration tool on its users using numerical models of the tool coupled to a finite element model of the human hand. This method can proactively warn very early, in the design process, the risks of causing musculoskeletal disorders and facilitate an optimization of the mechanical tool. This study is a first step in a context of human-centered design.
Acute camptocormia induced by olanzapine: a case report
Florence Robert, Martial Koenig, Aurélie Robert, Stéphane Boyer, Pascal Cathébras, Jean-Philippe Camdessanché
Journal of Medical Case Reports , 2010, DOI: 10.1186/1752-1947-4-192
Abstract: A 73-year-old Caucasian woman with no history of neuromuscular disorder, treated for chronic delusional disorder for the last ten years, received two injections of long-acting haloperidol. She was then referred for fatigue. Physical examination showed a frank parkinsonism without other abnormalities. Routine laboratory tests showed normal results, notably concerning creatine kinase level. Fatigue was attributed to haloperidol which was substituted for olanzapine. Our patient left the hospital after five days without complaint. She was admitted again three days later with acute back pain. Examination showed camptocormia and tenderness in paraspinal muscles. Creatine kinase level was elevated (2986 UI/L). Magnetic resonance imaging showed necrosis and edema in paraspinal muscles. Olanzapine was discontinued. Pain resolved quickly and muscle enzymes were normalized within ten days. Risperidone was later introduced without significant side-effect. The camptocormic posture had disappeared when the patient was seen as an out-patient one year later.Camptocormia is a heterogeneous syndrome of various causes. We believe that our case illustrates the need to search for paraspinal muscle damage, including drug-induced rhabdomyolysis, in patients presenting with acute-onset bent spine syndrome. Although rare, the occurrence of camptocormia induced by olanzapine must be considered.Camptocormia (bent spine syndrome) refers to an abnormal posture with marked flexion of the thoraco-lumbar spine which increases during walking and resolves in supine position. Originally attributed to psychogenic disorders (war hysteria), this symptom is an increasingly recognized feature of parkinsonian and dystonic disorders, but it may also be caused by neuromuscular disorders [1,2]. A fatty degeneration of paraspinal muscles has been reported in some cases, giving support to the "myopathic theory", but there is recent evidence that both central and peripheral mechanisms may be involved in the path
Pathologies Associated with Serum IgG4 Elevation
Mikael Ebbo,Aurélie Grados,Emmanuelle Bernit,Frederic Vély,José Boucraut,Jean-Robert Harlé,Laurent Daniel,Nicolas Schleinitz
International Journal of Rheumatology , 2012, DOI: 10.1155/2012/602809
Abstract: Statement of Purpose. IgG4-related disease (IgG4-RD) is usually associated to an increase of serum IgG4 levels. However other conditions have also been associated to high serum IgG4 levels. Methods. All IgG subclasses analyses performed in our hospital over a one-year period were analyzed. When IgG4 level were over 1.35?g/L, the patient’s clinical observation was analyzed and both final diagnosis and reason leading to IgG subclasses analysis were recorded. Only polyclonal increases of IgG4 were considered. Summary of the Results. On 646 IgG subclass analysis performed, 59 patients had serum IgG4 over 1.35?g/L. The final diagnosis associated to serum IgG4 increase was very variable. Most patients (25%) presented with repeated infections, 13.5% with autoimmune diseases, and 10% with IgG4-RD. Other patients presented with cancer, primary immune deficiencies, idiopathic interstitial lung disease, cystic fibrosis, histiocytosis, or systemic vasculitis and 13.5% presented with various pathologies or no diagnosis. Mean IgG4 levels and IgG4/IgG ratio were higher in IgG4-RD than in other pathologies associated to elevated IgG4 levels. Conclusions. Our study confirms that elevation of serum IgG4 is not specific to IgG4-RD. Before retaining IgG4-RD diagnosis in cases of serum IgG4 above 1.35?g/L, several other pathological conditions should be excluded. 1. Introduction Immunoglobulin G4 (IgG4) represents the less abundant of the four IgG subclasses in human serum accounting for 3 to 6% of the total IgG [1]. IgG4 has been associated with several pathological conditions. Most of these associations suggest a protective effect of IgG4, such as in allergen-specific immunotherapy [2] and protection from inflammatory manifestations during parasitosis [3]. In few situations, IgG4 is associated with a direct pathogenic effect, such as in pemphigus. During this blistering dermatosis, antidesmosome autoantibodies belong to the IgG4 subclass [4]. However, total IgG4 serum levels are not raised in these conditions. In 2001, Hamano et al. report a quantitative serum IgG4 elevation during sclerosing (or “autoimmune”) pancreatitis above the cutoff value of 135?mg/dL in 95% of patients with autoimmune pancreatitis [1]. This entity was first described in 1961 by Sarles and colleagues in patients with lymphoplasmacytic infiltrate and fibrosis of the pancreas associated to polyclonal hypergammaglobulinemia [5]. Polyclonal hypergammaglobulinemia raised initially the issue of the possible auto-immune nature of the disease, but this hypothesis has not been confirmed to date. Indeed, no
La Septième Porte. Réalités et représentations des conflits familiaux dans l’Athènes classique.
Aurélie Damet
Genre & Histoire , 2010,
Abstract: En étudiant la violence familiale dans l’Athènes classique des Ve et IVe siècles avant J. C, j’ai souhaité réconcilier des sources et des approches méthodologiques trop souvent cloisonnées. La dramaturgie, tragique et comique, les réflexions philosophiques platoniciennes et aristotéliciennes et les plaidoiries judiciaires méritent en effet d’être confrontées, afin de proposer une chronique intégrale de la parenté déchirée athénienne. Aux realia transmis par les traces juridiques du IVe siècle...
L’état du problème du logement à Quito
Aurélie Quentin
M@ppemonde , 2005,
Abstract: The housing problem in Quito take two different forms in the city, from the historical centre to the peripheral slums. Over the past ten years, the public response to these two sides of the problem has completely changed to comply with the rules of the good governance.
Günter Grass, peler l’oignon du souvenir
Aurélie Renault
m@gm@ , 2012,
Abstract: La publication en 2006 de l’autobiographie de Günter Grass, Pelures d’oignon, fait scandale : cet homme si engagé du c té des plus faibles s’est engagé volontairement dans la Waffen SS ! Cet aveu est difficile de la part de l’auteur. Il lui faut peler amèrement l’oignon du souvenir, multiplier les questions, cherchant alors des réponses pour comprendre son attitude d’alors, des réponses qui ne peuvent que le rendre coupable à ses yeux comme à celui de son lectorat. Aussi son pacte autobiographique tourne-t-il, pour l’essentiel, autour de la question du jugement. Il n’hésite pas à se dédoubler, faisant de son Moi passé un personnage que son Moi présent juge sévèrement. Les métaphores de la honte se multiplient, donnant lieu à un cache-cache entre les deux Moi de l’auteur qui ne va pas sans s’achever sur la victoire du Moi présent, lequel se dit coupable pour renforcer une thèse qui lui est chère, celle de la co-responsabilité : c’est l’ensemble du peuple allemand qui est co-responsable face au Mal nazi. Mémoire et Imagination se réconcilient au nom d’un engagement dont le présent prend acte.
Les réfugiés politiques espagnols en RDA
Aurélie Denoyer
Trajectoires , 2009,
Abstract: Les réfugiés politiques espagnols en RDA représentent le plus petit groupe de migrants que la RDA ait jamais accueilli. De sa constitution en 1951 à la mort de Franco en 1975, le collectif espagnol de Dresde compta entre 82 et 91 personnes. Cet exil espagnol dans le bloc de l'Est fut déclenché par l'opération Boléro-Paprika qui conduisit en septembre 1950 à l'expulsion vers la RDA de 33 Espagnols communistes résidant en France. La plupart n'en repartirent jamais. Dans cet article seront présentés l'accueil en RDA et la manière dont ce collectif se constitua. L'intégration de cette population en RDA sera elle aussi analysée. Dans un dernier temps, nous questionnerons la manière dont l'identité des enfants de ces exilés s'est constituée. Die politischen Flüchtlinge in der DDR sind die kleinste Migrantengruppe, die die DDR jemals aufgenommen hat. Das spanische Kollektiv in Dresden umfasste zwischen 82 und 91 Personen. Seinen Ursprung hatte dieses spanische Exil im Ostblock in der so genannten Operation Bolero-Paprika, die im Jahr 1950 zur Ausweisung von 33 spanischen Kommunisten aus Frankreich in die DDR führte. Die Mehrheit konnte dieses Land nie wieder verlassen. In diesem Beitrag wird die Aufnahme in der DDR und die Gründung dieses Kollektivs pr sentiert. Die Integration dieser Gruppe wird ebenfalls analysiert. Zudem wird der Frage der Identit tskonstruktion der Kinder nachgegangen.
Lucille Ball, the Queen of Show Business versus Lucy Ricardo, the Failed Actress
Aurélie Blot
Transatlantica : Revue d'études Américaines , 2011,
Abstract: Most American people, all generations taken into account, remember Lucille Ball as a great comic figure of the Fifties. Nonetheless, just a few people remember her as one of the most powerful women of her time. This might be because Lucille Ball refused to be considered as a businesswoman; she wanted to be seen as an actress above all. In this article, I will analyze how Lucille Ball became a businesswoman in spite of herself and how her success as an actress contributed to her success as a businesswoman.
Jacques Pothier. Les Nouvelles de Flannery O’Connor.
Aurélie Guillain
Transatlantica : Revue d'études Américaines , 2006,
Abstract: Dans cet ouvrage, J. Pothier présente de manière synthétique les deux recueils de nouvelles de Flannery O’Connor qui ont été rassemblés de manière posthume dans The Collected Short Stories. Il y dégage les deux grandes figures de la suffisance qui se pavanent dans ces nouvelles : la figure du Pharisien et celle de l’intellectuel progressiste, deux personnages également convaincus d’occuper la place de choix au sein de hiérarchies qu’ils ont eux mêmes con ues mais qui, au terme des intrigues, ...
Introduction
Aurélie Varrel
EchoGéo , 2009,
Abstract: L’Union indienne était considérée voici encore deux décennies comme l’exemple par excellence du pays dit en développement, voire pauvre, avec ce que cela impliquait de difficultés et de fragilités ; en témoignait la manière dont elle se trouvait traitée dans les programmes scolaires, où sa présence était par ailleurs fort discrète. Elle appara t désormais au deuxième rang des pays dits émergents. Certains lieux, secteurs d’activités et personnages incarnent pour le monde entier cette nouvelle...
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