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Search Results: 1 - 10 of 121683 matches for " Augusto Henriques Fulgêncio Brand?o "
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Dopplerfluxometria de artérias oftálmicas e avalia??o da fun??o endotelial nas formas precoce e tardia da pré-eclampsia
Brando, Augusto Henriques Fulgêncio;Barbosa, Alexandre Sim?o;Lopes, Ana Paula Brum Miranda;Leite, Henrique Vitor;Cabral, Ant?nio Carlos Vieira;
Radiologia Brasileira , 2012, DOI: 10.1590/S0100-39842012000100006
Abstract: objective: to identify possible differences between endothelial dysfunction evaluated by brachial artery flow-mediated dilation and central hyperperfusion evaluated by dopplerfluxometry of ophthalmic artery in women with early- and late-onset preeclampsia. materials and methods: flow-mediated dilation testing and dopplerfluxometry of ophthalmic artery were performed in 81 patients (26 with early preeclampsia, 30 with late preeclampsia, and 25 normotensive pregnant women - control group). results: as compared with the control group, patients with preeclampsia presented lower values of flow-mediated dilation, both in cases of early preeclampsia (7.62 ± 5.42% × 14.12 ± 6.14%; p = 0.02) and in cases of late preeclampsia (5.83 ± 4.12% × 14.12 ± 6.14%; p = 0.00). no statistically significant difference was observed between early- and late-onset preeclampsia (7.62 ± 5.42% × 5.83 ± 4.12%; p = 0.09). values for dopplerfluxometry of ophthalmic artery were significant lower in patients with preeclampsia as compared with the control group, both in cases of early preeclampsia (0.631 ± 0.024 × 0.737 ± 0.032; p = 0.01) and in cases of late preeclampsia (0.653 ± 0.019 × 0.737 ± 0.032; p = 0.03). again, no statistically significant difference was observed between early- and late-onset preeclampsia (0.631 ± 0.024 × 0.653 ± 0.019; p = 0.12). basically, the results demonstrate a decrease in values for dopplerfluxometry of ophthalmic artery in patients with early and late presentations of preeclampsia as compared with the control group, although with no statistically significant difference between the two presentations of the disease. conclusion: the present results indicate the presence of endothelial dysfunction and central hyperperfusion in patients with early- and late-onset preeclampsia.
Comparative Study of Endothelial Function and Uterine Artery Doppler Velocimetry between Pregnant Women with or without Preeclampsia Development
Augusto Henriques Fulgêncio Brando,Ludmila Maria Guimar?es Pereira,Alessandra Cristina de Oliveira Gon?alves,Zilma Silveira Nogueira Reis,Henrique Vítor Leite,Ant?nio Carlos Vieira Cabral
Journal of Pregnancy , 2012, DOI: 10.1155/2012/909315
Abstract: Background. Poor placentation and systemic endothelial dysfunction have been identified as main events in Preeclampsia (PE). The relationship and chronology of these phenomena are important if we are to understand the pathophysiological mechanisms underlying this major clinical problem. Objectives. To compare the evolution of placentation and endothelial function in normotensive and preeclamptic pregnancies. Patients and methods. In a prospective cohort study, 59 pregnant women with a high risk of developing PE were subjected to flow-mediated dilation (FMD) and to Doppler velocimetry of uterine arteries in order to obtain their Pulsatility Index (UtA-PI). The variations in the FMD and UtA-PI values, between 16+0 and 19+6 and 24+0 and 27+6 weeks of gestation, were compared, taking PE development into consideration. Results. Nine patients developed PE and the other 50 women remained normotensive. At 16+0 to 19+6 weeks of pregnancy, patients that developed PE presented higher values of UtA-PI than the normotensive group, but there was no difference in FMD results between them. At 24+0 to 27+6 weeks, the patients that developed PE presented higher values of UtA-PI and lower values of FMD than the women that remained normotensive. Conclusions. These results corroborate the evidence that endothelial injury is secondary to poor placentation. 1. Introduction Preeclampsia (PE) is a multisystemic disorder that accounts for a large number of maternal deaths in developed and developing countries worldwide [1–3]. Although its etiology remains unclear, several events in PE physiopathology are well studied and can be evaluated using biochemical or biophysical methods. In order to prevent PE complications, there are many early detection markers, which include maternal demographics, past medical, obstetric, family history, and some current pregnancy characteristics [4–6]. Maternal factors and history alone can be used as a PE risk stratification method. Elevated body mass index, maternal age extremes and Afro-American ethnicity are associated with a higher risk of PE [7]. Some diseases such as diabetes and chronic hypertension also significantly increase the risk [8]. The patients that present these conditions are the ones who will most benefit from a satisfactory and specific level of care, once the risk of developing PE in this groups rises threefold, reaching a PE prevalence of 45% [3]. Preeclampsia is essentially an endothelial disease [9, 10]. Progressive endothelial dysfunction leads to arterial hypertension, glomerular lesion, hepatic failure, and cerebral edema
Uso de fator VII recombinante ativado para tratamento e profilaxia de grandes sangramentos
Vince, Flávio Augusto Henriques;Brando, Maria José Nascimento;
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (S?o Paulo) , 2009, DOI: 10.1590/S0102-67202009000300007
Abstract: introduction: recombinant activated factor vii (rfviia) is a protein produced by genetic engineering, the structure is very similar to the structure of intrinsic activated factor vii (fvii). its action is based on knowledge of the coagulation mechanism in vivo by acting in direct activation of factor x independent resulting in formation of thrombin at the injury site and thereby contributing to the formation of stable fibrin clots without the action of factor viii and factor ix. methods: was conducted extensive review of the literature in order to determine the new findings related to the use of recombinant activated factor vii in patients with severe bleeding. results: it was found that the use of rfviia started in the 80's for prophylaxis and treatment of bleeding in patients with a history of hemophilia a or b with inhibitors to factor viii and ix, factor vii deficiency and glanzmann's thrombasthenia refractory to replacement platelet. in 1999 its use was expanded to other clinical situations and thus began to be published several studies showing the efficacy of rfviia as a pro-hemostatic agent in patients with bleeding disorders or other previously healthy patients with a history of acute bleeding of major consequence. trauma is the leading cause of mortality worldwide and uncontrolled bleeding the main challenge in caring for these patients. it is common for the association of trauma with coagulopathy, requiring in some cases specific therapy to treat it. at this point in adjuvant therapy with rfviia should be considered. other common causes of bleeding are the heart, gynecologic/obstetric surgeries and diseases involving the liver. the coagulopathy in these cases is deficiency of factors dependent on vitamin k, and the fvii factor with smaller half life. conclusion: the use of rfviia has been suggested as a promising therapeutic option for these patients. thus, the recent increase in the use of rfviia in situations not approved has led to growing questions abo
Uveíte por tuberculose em um centro de referência no Sudeste do Brasil Tuberculous uveitis at a referral center in southeastern Brazil
Wesley Ribeiro Campos,Juliana Fulgêncio Henriques,Afranio Lineu Kritski,André Curi
Jornal Brasileiro de Pneumologia , 2008,
Abstract: OBJETIVO: Descrever a ocorrência de uveíte por tuberculose (UTB) em um centro de referência em Minas Gerais, Brasil. MéTODOS: Um total de 16 pacientes (idade > 15 anos) atendidos consecutivamente de janeiro de 2001 a julho de 2004 no Centro de Referência de Uveíte do Estado de Minas Gerais para avalia o diagnóstica de uveíte foi selecionado para este estudo. Foram coletados dados demográficos e clínicos, assim como dados sobre avalia o para toxoplasmose, sífilis e doen as reumatológicas, teste tuberculínico e sorologia anti-HIV. RESULTADOS: Dos 16 pacientes, 11 (69%) tinham UTB. História prévia de contato com tuberculose pulmonar foi relatada por 72% (8/11) dos pacientes do grupo com UTB e por 20% (1/5) dos pacientes do grupo sem UTB. Embora a raz o de chances para essa associa o tenha sido de 10,67 (IC95%: 0,59-398,66), o valor de p apresentou significancia limítrofe (0,078). N o houve diferen a quanto ao quadro ocular inflamatório e ao resultado do teste tuberculínico entre os pacientes com UTB e os sem UTB. Todos os pacientes tinham sorologia negativa para o HIV e foram acompanhados por 2 anos. CONCLUS ES: Neste estudo, a história prévia de contato com tuberculose pulmonar foi de grande ajuda para o diagnóstico da UTB. OBJECTIVE: To describe the occurrence of tuberculous uveitis (TBU) at a referral center in the state of Minas Gerais, Brazil. METHODS: A total of 16 consecutive patients (>15 years of age) who underwent diagnostic evaluation of uveitis between January of 2001 and July of 2004 at the Minas Gerais State Referral Center were selected for study. Demographic and clinical data, as well as data related to screening for toxoplasmosis, syphilis, and rheumatologic diseases, together with the results of tuberculin skin testing and HIV testing, were collected. RESULTS: Of the16 patients evaluated, 11 (69%) were found to have TBU. A history of contact with pulmonary tuberculosis was reported by 8 (72%) of the 11 patients with TBU and by 1 (20%) of the 5 with non-TBU. Although the odds ratio for this association was 10.67 (95% CI: 0.59-398.66), the p value was borderline significant (p = 0.078). There was no difference between the patients with TBU and those with non-TBU in terms of the status of ocular inflammation or the tuberculin skin testing results. All of the patients were HIV negative and were monitored for two years. CONCLUSION: In this study, a history of contact with pulmonary tuberculosis proved to be useful in diagnosing TBU.
Uveíte por tuberculose em um centro de referência no Sudeste do Brasil
Campos, Wesley Ribeiro;Henriques, Juliana Fulgêncio;Kritski, Afranio Lineu;Curi, André;Pimentel, Rosita Tomishi;Spindola de Miranda, Silvana;
Jornal Brasileiro de Pneumologia , 2008,
Abstract: objective: to describe the occurrence of tuberculous uveitis (tbu) at a referral center in the state of minas gerais, brazil. methods: a total of 16 consecutive patients (>15 years of age) who underwent diagnostic evaluation of uveitis between january of 2001 and july of 2004 at the minas gerais state referral center were selected for study. demographic and clinical data, as well as data related to screening for toxoplasmosis, syphilis, and rheumatologic diseases, together with the results of tuberculin skin testing and hiv testing, were collected. results: of the16 patients evaluated, 11 (69%) were found to have tbu. a history of contact with pulmonary tuberculosis was reported by 8 (72%) of the 11 patients with tbu and by 1 (20%) of the 5 with non-tbu. although the odds ratio for this association was 10.67 (95% ci: 0.59-398.66), the p value was borderline significant (p = 0.078). there was no difference between the patients with tbu and those with non-tbu in terms of the status of ocular inflammation or the tuberculin skin testing results. all of the patients were hiv negative and were monitored for two years. conclusion: in this study, a history of contact with pulmonary tuberculosis proved to be useful in diagnosing tbu.
Perfil funcional de pacientes portadores de seqüela de tuberculose de um hospital universitário
Ramos, Lucia Maria Macedo;Sulmonett, Nara;Ferreira, Cid Sergio;Henriques, Juliana Fulgêncio;Miranda, Silvana Spíndola de;
Jornal Brasileiro de Pneumologia , 2006, DOI: 10.1590/S1806-37132006000100010
Abstract: objective: to describe data related to the pulmonary function of patients with sequelae of pulmonary tuberculosis, pleural tuberculosis or both. methods: in the outpatient clinic of a university hospital, 218 patients were evaluated. of those 218, 56 had sequelae of tuberculosis (pulmonary, pleural or both), and 162 had other types of tuberculosis. all patients were evaluated in the pulmonary function laboratory between february 2000 and july 2004, and 43 were found to be eligible for inclusion in the study. patients with a history of asthma, chronic pulmonary obstructive disease, cardiac insufficiency, collagen diseases, silicosis or thoracic surgery, as well as those for whom spirometry yielded unacceptable results or was not performed, were excluded. the lung fields were divided into six zones, and radiographic results were classified by degree: i (involvement of only one zone with no cavitation); ii (involvement of two or three zones or of one zone with cavitation); or iii (extensive involvement of three or more zones with or without cavitation). results: the final study sample comprised 50 patients, 44 (88%) of whom had pulmonary tuberculosis. the most prevalent form (17/50; 34%) was mixed ventilatory disturbance. severe disturbances were more significant in degree iii radiographs (p = 0.0002) and normal pulmonary function was predominant among patients presenting degree i and ii radiographs (p = 0.002). conclusion: the early discovery and treatment of tuberculosis contribute to reduce the number of cases, as well as the incidence of tuberculosis sequelae, thereby improving the quality of life of tuberculosis patients. further studies, involving longitudinal, sequential analysis and larger samples of patients with tuberculosis sequelae, should be conducted in referral centers in brazil.
Rompendo barreiras educacionais: negros no ensino superior
André Augusto Brando
Physis: Revista de Saúde Coletiva , 2004, DOI: 10.1590/s0103-73312004000100011
Abstract:
Conceitos e Coisas: Robert Castel, A “Desfilia o” e a Pobreza Urbana no Brasil
André Augusto Brando
Revista Emancipa??o , 2002,
Abstract: Este artigo discute os pontos de afastamento e de convergência entre os processos recentes de aprofundamento da pobreza urbana no Brasil e as contribui es de R. Castel acerca das modifica es do mercado de trabalho e da lógica da integra o social na sociedade francesa atual. Na medida em que este autor tem hoje lugar cativo em muitas disciplinas de nossa área, trata-se aqui de pensar na adequa o de suaproblemática às quest es brasileiras.
Tabanidae (Diptera) do Estado do Maranh?o, Brasil: IV. Descri??o de Dichelacera (Dichelacera) gemmae sp.n.
Limeira-de-Oliveira, Francisco;Gorayeb, Inocêncio de S;Henriques, Augusto L;
Neotropical Entomology , 2009, DOI: 10.1590/S1519-566X2009000100011
Abstract: dichelacera (dichelacera) gemmae sp.n. is described based on 28 females collected in open vegetation of "cerrado", in carolina municipality, south of maranh?o state, brazil.
Nina Rodrigues e a patologiza??o do crime no Brasil
Augusto, Cristiane Brando;Ortega, Francisco;
Revista Direito GV , 2011, DOI: 10.1590/S1808-24322011000100011
Abstract: the current work aims at performing an analysis of the criminals "pathologization" movement by means of a historical reading of the impact of ''brain scientificism" in the criminal sphere. more particularly, there is an emphasis on the reception of the lombrosionism matrix theories in 1 9th-century brazilian criminology, in which we can see the microcosms of classes and races conflicts of interests, mediated by the medical authority who, in his scientific beliefs ?or in his ideological filiations), looked for illuminate the limits between the moral fault and the madness - or the both (moral madness) as pathology or as pure perversity -and tried to show the correct form ?scientific} of punishing or treating.
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