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Serous cystadenoma with co-existing stromal tumor with sex-cord stromal elements: An extremely rare tumor  [PDF]
Asavari A. Bachhav
Open Journal of Obstetrics and Gynecology (OJOG) , 2014, DOI: 10.4236/ojog.2014.43019

Surface epithelial-stromal tumors are the most common neoplasm of ovary in the reproductive age and beyond. Less than 1% of epithelial ovarian tumors occur before the age of 21 years while 75% of sexcord stromal tumors (Sertoli and Leydig Cell) occur in the third and fourth decades of life. Serous tumors rarely occur in combination with germ cell tumors, sex-cord stromal tumors or granulosa cell tumors. Thus it is extremely rare for a combination of the above two tumors to occur before 21 years although a case report for a tumor with epithelial, stromal and sex-cord stromal elements for a 58-year-old patient has been documented. We believe ours is the first case in literature of a massive Serous Cystadenoma with co-existing stromal tumor with minor sex-cord stromal (Sertoli-Leydig Cell) elements.

Chondroprotective Potential of Fruit Extracts of Phyllanthus emblica in Osteoarthritis
Venil N. Sumantran,Asavari Kulkarni,Rucha Chandwaskar,Abhay Harsulkar,Bhushan Patwardhan,Arvind Chopra,Ulhas V. Wagh
Evidence-Based Complementary and Alternative Medicine , 2008, DOI: 10.1093/ecam/nem030
Abstract: There is a need for effective nutraceuticals for osteoarthritis care. The fruit of Phyllanthus emblica is used as a powerful rejuvenator in Ayurvedic medicine. This study measured the chondroprotective potential of P. emblica (‘Amalaki’) fruits in vitro. We used aqueous extracts of unprocessed P. emblica fruit powder (powder A), and the powder obtained after hot water extraction and drying of powder A (powder B). Chondroprotection was measured in three different assay systems. First, we tested the effects of both fruit powders on the activities of the enzymes hyaluronidase and collagenase type 2. Second, an in vitro model of cartilage degradation was set-up with explant cultures of articular knee cartilage from osteoarthritis patients. Cartilage damage was assayed by measuring glycosaminoglycan release from explants treated with/without P. emblica fruit powders. Aqueous extracts of both fruit powders significantly inhibited the activities of hyaluronidase and collagenase type 2 in vitro. Third, in the explant model of cartilage matrix damage, extracts of glucosamine sulphate and powder B (0.05 mg/ml) exhibited statistically significant, long-term chondroprotective activity in cartilage explants from 50% of the patients tested. This result is important since glucosamine sulphate is the leading nutraceutical for osteoarthritis. Powder A induced a statistically significant, short-term chondroprotective activity in cartilage explants from all of the patients tested. This is the first study to identify and quantitate new chondroprotective activities of P. emblica fruits. These data provide pilot pre-clinical evidence for the use of P. emblica fruits as a chondroprotective agent in osteoarthritis therapy.
A Dynamical Model to Analyze the Influence of Sliding Friction on Motion on a Curve—An Analytical Method  [PDF]
Prahlad Kulkarni
Open Journal of Applied Sciences (OJAppS) , 2015, DOI: 10.4236/ojapps.2015.58043
Abstract: To demonstrate the influence of sliding friction of motion on a curve, a circular path is considered for simplicity on which a person slides from the highest point to the lowest point. A slide which represents a quadrant of radius 5 m and a person of mass 60 kg are considered for comparison in this paper. A Differential equation for motion considering the fact that the normal force depends both on the sin component of weight and also on the tangential velocity, is established and is solved using integrating factor method, and the motion is analysed for different surface roughness of the slide and is compared using superimposed graphs, also the limiting value of friction coefficient at which the person just exits the slide is determined. The correction factor for exit velocity with friction as compared with the exit velocity for zero friction is determined. The fraction of energy lost to friction at the exit is evaluated. The Variation of normal force with the position of the person on the slide is plotted for different surface roughness of the slide, and the position on the slide where the normal force or the force experienced by the person is maximum, is determined and hence its maximum value is evaluated for different surface roughness. For simplicity, a point contact between the body and the slide is considered.
Flux pinning characteristics in cylindrical ingot niobium used in superconducting radio frequency cavity fabrication
Asavari S. Dhavale,Pashupati Dhakal,Anatolii A. Polyanskii,Gianluigi Ciovati
Physics , 2012, DOI: 10.1088/0953-2048/25/6/065014
Abstract: We present the results of from DC magnetization and penetration depth measurements of cylindrical bulk large-grain (LG) and fine-grain (FG) niobium samples used for the fabrication of superconducting radio frequency (SRF) cavities. The surface treatment consisted of electropolishing and low temperature baking as they are typically applied to SRF cavities. The magnetization data were fitted using a modified critical state model. The critical current density Jc and pinning force Fp are calculated from the magnetization data and their temperature dependence and field dependence are presented. The LG samples have lower critical current density and pinning force density compared to FG samples which implies a lower flux trapping efficiency. This effect may explain the lower values of residual resistance often observed in LG cavities than FG cavities.
Structural Properties of Optimal Scheduling Policies for Wireless Data Transmission  [PDF]
Nomesh Bolia, Vidyadhar Kulkarni
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2012, DOI: 10.4236/ijcns.2012.510069
Abstract: We analyze a cell with a fixed number of users in a time period network. The base station schedules to serve at most one user in a given time period based on information about the available data rates and other parameter(s) for all the users in the cell. We consider infinitely backlogged queues and model the system as a Markov Decision Process (MDP) and prove the monotonicity of the optimal policy with respect to the \"starvation age\" and the available data rate. For this, we consider both the discounted as well as the long-run average criterion. The proofs of the monotonicity properties serve as good illustrations of analyzing MDPs with respect to their optimal solutions.
Single Flap Otoendoscopic Myringoplasty for Large Central Perforation—A Pilot Study  [PDF]
Vikram Kulkarni, Mudit Mittal
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2014, DOI: 10.4236/ijohns.2014.34030

Introduction: Otoendoscopic myringoplasty has been successfully used for repair of small to medium sized perforation using various materials. Very few studies have used this method for repair of large central perforation. Goals: To evaluate the transcanal otoendoscopic approach to reconstruct large central perforation by raising single flap. Methods Utilized: Pilot study on forty patients with chronic suppurative otitis media dry stage with large central perforation in medical college hospital and research centre was conducted. A zero degree 4 mm otoendoscope and custom made suction elevator was used for myringoplasty. Results: The perforation of thirty eight patients had healed by the end of two months. Conclusion: Otoendoscopic myringoplasty is effective in managing large central perforation and patients need to be observed for longer period to calculate the successful rate.

Acute toxicity of Cypermethrin, a synthetic pyrethroid to estuarine clam Katelysia opima (Gmelin) and its effect on oxygen consumption  [PDF]
Madhura Mukadam, Arvind Kulkarni
Journal of Agricultural Chemistry and Environment (JACEN) , 2014, DOI: 10.4236/jacen.2014.34016
Abstract: The impact of acute exposure of Cypermethrin on the rate of oxygen consumption of the estuarine clam, Katelysia opima was studied. After 12, 24, 36, 48, 60, 72 84 and 96 h of exposure to acute concentration, the average oxygen consumption in LC0 group was 0.215, 0.305, 0364, 0.355, 0.362, 0.376, 0.313, 0.305, 0.297 (ml/L/hr/gm) and in LC50 group it was 0.210, 0.299, 0.356, 0.247, 0.217, 0.244, 0.203, 0.186, 0.174 (ml/L/hr/gm). It was observed that the rate of oxygen consumption fluctuated with an increase in the exposure period. The decrease was maximum in LC50 group as compared to LC0 group.
Evaluation of Reproductive Characteristics of 21 Highly Inbred Lines of White Leghorns Divergently Selected for or Segregating in Tumor Resistance  [PDF]
Gururaj Kulkarni, Huanmin Zhang
Open Journal of Animal Sciences (OJAS) , 2015, DOI: 10.4236/ojas.2015.51008
Abstract: Reproduction performance of 21 inbred experimental lines of White Leghorns was evaluated based on samples of reproduction records over a period of eight consecutive years. Two lines (63 and 72) have been extensively used in studies, especially in research seeking for genetic and epigenetic factors underlying resistance to avian tumor virus-induced diseases in chickens. The other 19 lines are recombinant congenic strains (RCS), which were generated by crossing lines 63 and 72 followed by two consecutive backcrosses to the line 63 and then full-sib mating. In theory, each RCS processes 7/8 of progenitor background line 63 genome and a random sample (1/8) of the progenitor donor line 72 genome. All 21 inbred lines share a common major histocompatibility complex haplotype, B*2. The estimated average fertility of the 21 inbred lines ranged from 72.9% (RCS-J) up to 96.8% (RCS-P). Both progenitor lines 63 and 72 were observed with lower average fertility (82.4% and 81.6%, respectively) in comparison with the RCS except the RCS-J, suggesting a substantial polygenic component underlying the fertility phenotype. The average embryo mortality rate ranged from 14.5% (RCS-P) up to 47.0% (RCS-M). The background line 63 fell at about the middle of the range (28.3%) significantly higher than the donor line 72 (15.7%), which was among the group with the lowest embryo mortality. By definition, hatchability of fertile eggs is reversely correlated with embryo mortality. The average hatchability ranged from 26.5% (RCS-M) up to 66.8% (line 72) while the background line 63 remained (46.6%) at about the middle of the range. The variability of the average embryo mortality and hatchability observed among the 21 inbred lines indicated the two correlated traits also follow polygenic models of inheritance. Findings from this study paves the way for further investigation on genetic and environmental influence over reproductive performance of inbred lines of chickens, and particularly in understanding and improving the reproduction fitness of invaluable genetic resources like these inbred lines.
Variations in arterial supply of vermiform appendix
Kulkarni UK,Kulkarni DU
International Journal of Anatomical Variations , 2011,
Abstract: Till date appendix holds the same surgical significance, which it had previously. The appendicular artery is considered to be a branch from posterior caecal artery or ileocolic artery entering the mesoappendix from behind the ileum and supplying it. During routine cadaveric dissections some variations were seen in number and course of the appendicular artery. Such three cases of surgical importance along with their review of literature are discussed herewith.
An Open Source P2P Encrypted VoIP Application
Ajay Kulkarni,Saurabh Kulkarni
Computer Science , 2014, DOI: 10.14569/IJACSA.2014.050601
Abstract: Open source is the future of technology. This community is growing by the day; developing and improving existing frameworks and software for free. Open source replacements are coming up for almost all proprietary software nowadays. This paper proposes an open source application which could replace Skype, a popular VoIP soft phone. The performance features of the developed software is analyzed and compared with Skype so that we can conclude that it can be an efficient replacement. This application is developed in pure Java using various APIs and package and boasts features like voice calling, chatting, file sharing etc. The target audience for this software will initially only be organizations (for internal communication) and later will be released on a larger scale.
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