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Search Results: 1 - 10 of 429284 matches for " Arve S?b? "
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Chronic Consequences of Uncomplicated Yersinia Enterocolitica Infection: A Retrospective Study (2004) of Military Recruits Previously (1987) Screened for Antibodies to Yersinia Enterocolitica O:3  [PDF]
Arve Sb, Karin Nygard, Georg Kapperud, J?rgen Lassen
International Journal of Clinical Medicine (IJCM) , 2011, DOI: 10.4236/ijcm.2011.22024
Abstract: In 1987, a serological survey among 755 male Norwegian military recruitsshowed that 68 (9.0%) had IgG (7.4%) and / or IgA (4.5%) antibodiesto Y.enterocolitica O:3, consistent with previous infection.In 2004,433 of the former recruits (mean age 37.5 years, range 35 - 42 years) answered a questionnaire, in order to investigatedevelopment of possible chronic disorders and complaints related to uncomplicated Y.enterocolitica infection. The questionnaire covered per-sonal and demographic data, behavioral risk factors, and possible chronic complaints related to yersiniosis.Among the 433 responders, 51 (11.8%) were seropositive for IgG or IgA in the 1987 survey, 380 were seronegative, and 2 had ambiguous results.No difference was observed between the seropositive and seronegativegroups regarding education, annual income, general behavioral risk factors like smoking, alcohol consumption, physical activity, and dietary parameters; or diagnosed chronic illness. However, the seropositives weresignificantly more likely than the seronegatives to report recurrent diarrhea, painful or swollen joints, and muscle pain. Also, presence of all three complaints was more common among seropositives. Conclusion: The present study shows that uncomplicated Y.enterocolitica O:3 infection is a risk factor regarding future development of chronic complaintssuch as diarrhea, and joint and muscle complaint.
A new development for occupational health services in Norway
Arve Lie
SJWEH Supplements , 2009,
Abstract: Occupational health services (OHS) in Norway are multidisciplinary. The OHS units are quite small, compared to other European countries, with an average of four full-time OHS professionals covering 2000 employees. All are financed by employers. Approximately half of the working population is covered by an OHS. Norwegian work environment legislation sets out which enterprises are obliged to have an OHS, what types of services are to be delivered, and the importance of the impartiality of the OHS. The main focus of an OHS should be to play an expert and advisory role in the health, environmental, and safety policy and activities of the enterprise. A recent governmental report proposed a certification system for OHS in Norway and a further expansion of obligatory OHS to include some new lines of businesses, for example the healthcare and education sectors. The key objectives and tasks for future OHS should be the same as today, but with an increased effort on the reduction of sickness absence and promotion of early return to work.
Pharmaceutical-grade albumin: impaired drug-binding capacity in vitro
Harald Olsen, Anders Andersen, Arve Nordb?, Ulf E Kongsgaard, Ole P B?rmer
BMC Pharmacology and Toxicology , 2004, DOI: 10.1186/1472-6904-4-4
Abstract: The binding properties of the various albumin solutions were tested in vitro by means of ultrafiltration. Naproxen, warfarin, and digitoxin were used as ligands. HPLC was used to quantitate the total and free drug concentrations. The data were fitted to a model of two classes of binding sites for naproxen and warfarin and one class for digitoxin, using Microsoft Excel and Graphpad Prism.The drugs were highly bound to albumin (95–99.5%). The highest affinity (lowest K1) was found with naproxen. Pharmaceutical-grade albumin solutions displayed significantly lower drug-binding capacity compared to native human serum and Sigma albumin. Thus, the free fraction was considerably higher, approximately 40 times for naproxen and 5 and 2 times for warfarin and digitoxin, respectively. The stabilisers caprylic acid and N-acetyl-DL-tryptophan used in the manufacturing procedure seem to be of importance. Adding the stabilisers to human serum and Sigma albumin reduced the binding affinity whereas charcoal treatment of the pharmaceutical-grade albumin from Octapharma almost restored the specific binding capacity.This in vitro study demonstrates that the specific binding for warfarin and digitoxin is significantly reduced and for naproxen no longer detectable in pharmaceutical-grade albumin. It further shows that the addition of stabilisers may be of major importance for this effect.Albumin is the most abundant protein in blood plasma. One of its main functions is transporting endogenous and exogenous compounds, which might be toxic in the unbound state, but non-toxic as albumin-bound. Thus the albumin may serve as a circulating depot, whereas the unbound substances are the pharmacologically active moieties [1,2]. Changes in the free drug concentration due to displacement or pathological states like impaired renal or liver function and hypoalbuminaemia may increase drug effect, particularly if the drug is highly albumin-bound [3]. Albumin also plays an essential role in generating t
Domínguez,Erwin; Elvebakk,Arve;
Gayana. Botánica , 2002, DOI: 10.4067/S0717-66432002000100007
Abstract: this is a report on the presence of lecanophora subacaule krapov. (malvaceae), collected for the first time in the pali aike national park, magallanes, chile. argentinean and chilean distribution and species description are provided
Erwin Domínguez,Arve Elvebakk
Gayana. Botanica , 2002,
Abstract: Se da cuenta del hallazgo de Lecanophora subacaule Krapov. (Malvaceae), colectada por primera vez en Chile en el Parque Nacional Pali Aike, ubicado en la provincia de Magallanes, XII Región. Se entrega la descripción de la especie y se indica su distribución en Argentina y Chile This is a report on the presence of Lecanophora subacaule Krapov. (Malvaceae), collected for the first time in the Pali Aike National Park, Magallanes, Chile. Argentinean and Chilean distribution and species description are provided
D delighet av/med diabetes
Aage Tverdal,Arve Sj?lingstad
Norsk Epidemiologi , 2009,
Abstract: -
On Capability-Related Adaptation in Networked Service Systems
Finn Arve Aagesen,Patcharee Thongtra
International Journal of Computer Networks & Communications , 2012,
Abstract: Adaptability is a property related to engineering as well as to the execution of networked service systems. This publication considers issues of adaptability both within a general and a scoped view. The generalview considers issues of adaptation at two levels: 1) System of entities, functions and adaptability types, and 2) Architectures supporting adaptability. Adaptability types defined are capability-related, functionality-related and context-related adaptation. The scoped view of the publication is focusing on capability-related adaptation. A dynamic goal-based policy ontology is presented. The adaptation functionality is realized by the combination of Extended Finite State Machines, Reasoning Machines andLearning Mechanisms. An example case demonstrating the use of a dynamic goal-based policy is presented
World Health Organization Estimates of the Global and Regional Disease Burden of 11 Foodborne Parasitic Diseases, 2010: A Data Synthesis
Paul R. Torgerson?,Brecht Devleesschauwer?,Nicolas Praet?,Niko Speybroeck?,Arve Lee Willingham?,Fumiko Kasuga?,Mohammad B. Rokni?,Xiao-Nong Zhou?,Eric M. Fèvre?,Banchob Sripa
PLOS Medicine , 2015, DOI: 10.1371/journal.pmed.1001920
Abstract: Background Foodborne diseases are globally important, resulting in considerable morbidity and mortality. Parasitic diseases often result in high burdens of disease in low and middle income countries and are frequently transmitted to humans via contaminated food. This study presents the first estimates of the global and regional human disease burden of 10 helminth diseases and toxoplasmosis that may be attributed to contaminated food. Methods and Findings Data were abstracted from 16 systematic reviews or similar studies published between 2010 and 2015; from 5 disease data bases accessed in 2015; and from 79 reports, 73 of which have been published since 2000, 4 published between 1995 and 2000 and 2 published in 1986 and 1981. These included reports from national surveillance systems, journal articles, and national estimates of foodborne diseases. These data were used to estimate the number of infections, sequelae, deaths, and Disability Adjusted Life Years (DALYs), by age and region for 2010. These parasitic diseases, resulted in 48.4 million cases (95% Uncertainty intervals [UI] of 43.4–79.0 million) and 59,724 (95% UI 48,017–83,616) deaths annually resulting in 8.78 million (95% UI 7.62–12.51 million) DALYs. We estimated that 48% (95% UI 38%-56%) of cases of these parasitic diseases were foodborne, resulting in 76% (95% UI 65%-81%) of the DALYs attributable to these diseases. Overall, foodborne parasitic disease, excluding enteric protozoa, caused an estimated 23.2 million (95% UI 18.2–38.1 million) cases and 45,927 (95% UI 34,763–59,933) deaths annually resulting in an estimated 6.64 million (95% UI 5.61–8.41 million) DALYs. Foodborne Ascaris infection (12.3 million cases, 95% UI 8.29–22.0 million) and foodborne toxoplasmosis (10.3 million cases, 95% UI 7.40–14.9 million) were the most common foodborne parasitic diseases. Human cysticercosis with 2.78 million DALYs (95% UI 2.14–3.61 million), foodborne trematodosis with 2.02 million DALYs (95% UI 1.65–2.48 million) and foodborne toxoplasmosis with 825,000 DALYs (95% UI 561,000–1.26 million) resulted in the highest burdens in terms of DALYs, mainly due to years lived with disability. Foodborne enteric protozoa, reported elsewhere, resulted in an additional 67.2 million illnesses or 492,000 DALYs. Major limitations of our study include often substantial data gaps that had to be filled by imputation and suffer from the uncertainties that surround such models. Due to resource limitations it was also not possible to consider all potentially foodborne parasites (for example Trypanosoma cruzi). Conclusions
Use of Oxfendazole to Control Porcine Cysticercosis in a High-Endemic Area of Mozambique
Alberto Pondja ,Luís Neves,James Mlangwa,Sónia Afonso,José Fafetine,Arve Lee Willingham III,Stig Milan Thamsborg,Maria Vang Johansen
PLOS Neglected Tropical Diseases , 2012, DOI: 10.1371/journal.pntd.0001651
Abstract: A randomized controlled field trial to evaluate the effectiveness of a single oral dose of 30 mg/kg of oxfendazole (OFZ) treatment for control of porcine cysticercosis was conducted in 4 rural villages of Angónia district, north-western Mozambique. Two hundred and sixteen piglets aged 4 months were selected and assigned randomly to OFZ treatment or control groups. Fifty-four piglets were treated at 4 months of age (T1), while another 54 piglets were treated at 9 months of age (T2) and these were matched with 108 control pigs from the same litters and raised under the same conditions. Baseline data were collected on the prevalence of porcine cysticercosis using antigen ELISA (Ag-ELISA), as well as knowledge and practices related to Taenia solium transmission based on questionnaire interviews and observations. All animals were followed and re-tested for porcine cysticercosis by Ag-ELISA at 9 and 12 months of age when the study was terminated. Overall prevalence at baseline was 5.1% with no significant difference between groups. At the end of the study, 66.7% of the controls were found positive, whereas 21.4% of the T1 and 9.1% of the T2 pigs were positive, respectively. Incidence rates of porcine cysticercosis were lower in treated pigs as compared to controls. Necropsy of 30 randomly selected animals revealed that viable cysts were present in none (0/8) of T2 pigs, 12.5% (1/8) of T1 pigs and 42.8% (6/14) of control pigs. There was a significant reduction in the risk of T. solium cysticercosis if pigs were treated with OFZ either at 4 months (OR = 0.14; 95% CI: 0.05–0.36) or at 9 months of age (OR = 0.05; 95% CI: 0.02–0.16). Strategic treatment of pigs in endemic areas should be further explored as a means to control T. solium cysticercosis/taeniosis.
Prevalence and Risk Factors of Porcine Cysticercosis in Angónia District, Mozambique
Alberto Pondja ,Luís Neves,James Mlangwa,Sónia Afonso,José Fafetine,Arve Lee Willingham III,Stig Milan Thamsborg,Maria Vang Johansen
PLOS Neglected Tropical Diseases , 2010, DOI: 10.1371/journal.pntd.0000594
Abstract: Taenia solium is an important zoonosis in many developing countries. Cysticercosis poses a serious public health risk and incurs sizeable economic losses to pig production. Because data on the epidemiology of porcine cysticercosis in Mozambique are scarce, the present study was conducted to determine the prevalence and risk factors for porcine cysticercosis. A cross-sectional survey was carried out in 11 villages in Angónia district, Tete province in northwestern Mozambique. Between September and November, 2007, a total of 661 pigs were tested serologically and examined by tongue inspection. Serum samples were tested for the presence of circulating parasite antigen using a monoclonal antibody-based sandwich enzyme-linked immunosorbent assay (Ag-ELISA). In addition, a questionnaire survey to collect information on pig production, occurrence and transmission of porcine cysticercosis, risk factors and awareness of porcine cysticercosis was conducted in the selected households from which pigs were sampled. Two hundred thirty-one samples (34.9%) were found positive by the Ag-ELISA, while by tongue inspection on the same animals cysticerci were detected in 84 pigs (12.7%). Increasing age (OR = 1.63; 95% CI = 1.13–2.37) and free-range pig husbandry system (OR = 3.81; 95% CI = 2.08–7.06) were important risk factors for porcine cysticercosis in the district. The present findings indicate that porcine cysticercosis is endemic in the region, and that increasing pig age and pig husbandry practices contribute significantly to porcine cysticercosis transmission. Further epidemiological studies on the prevalence and transmission of porcine cysticercosis in rural communities in Mozambique are needed to enable collection of more baseline data and implementation of effective control strategies within the country.
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