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Search Results: 1 - 10 of 44366 matches for " Antonio Di Carluccio "
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Some Remarks on the Seismic Demand Estimation in the Context of Vulnerability Assessment of Large Steel Storage Tank Facilities
Antonio Di Carluccio,Giovanni Fabbrocino
ISRN Civil Engineering , 2012, DOI: 10.5402/2012/271414
Some Remarks on the Seismic Demand Estimation in the Context of Vulnerability Assessment of Large Steel Storage Tank Facilities
Antonio Di Carluccio,Giovanni Fabbrocino
ISRN Civil Engineering , 2012, DOI: 10.5402/2012/271414
Abstract: The seismic behavior of steel tanks is relevant in industrial risk assessment because collapse of these structures may trigger other catastrophic phenomena due to loss of containment. Therefore, seismic assessment should be focused on for leakage-based limit states. From a seismic structural perspective, damages suffered by tanks are generally related to large axial compressive stresses, which can induce shell buckling near the base and large displacements of unanchored structures resulting in the detachment of piping. This paper approaches the analysis of seismic response of sliding, nonuplifting, unanchored tanks subject to seismic actions. Simplified methods for dynamic analysis and seismic demand estimation in terms of base displacement and compressive shell stress are analyzed. In particular, attention is focussed on some computational issues related to the solution of the dynamic problem and on the extension of the incremental dynamic analysis (IDA) technique to storage tanks. 1. Introduction Earthquakes represent an external hazard for industrial installations and may trigger accidents, that is, fire and explosions resulting in injury to people and to near field equipments or constructions, whenever structural failures result in the release of hazardous material. In recent years the quantitative risk analysis (QRA) procedures have been extended to include seismic analysis for industrial installation, for example, petrochemical plants, and chemical plants, storage facility [1–3]. From the structural perspective, steel tanks for oil storage are standardized structures both in terms of design and construction [4–6]. A review of the international standards points out that the design procedures evolved slowly. Nevertheless, a large number of postearthquake damage observations [7] are available and empirical vulnerability functions have been developed [8]. This is a privileged case with respect to other civil engineering structures that basically can be seen as single prototypes; however, empirical fragility typically suffers some shortcomings. In fact, site effects can influence vulnerability data, so that a disaggregation is hard to perform. Therefore, the development of analytical models able to predict the response of the structural components and systems under seismic loading is worth exploring. The present work is aimed at discussing a numerical procedure able to analyze the response of anchored and unanchored tanks under two-dimensional ground motion accounting for the structure sliding. The main objective of the study is, in particular, the
The BP-M* Methodology for Process Analysis in the Health Sector  [PDF]
Antonio Di Leva, Salvatore Femiano
Intelligent Information Management (IIM) , 2011, DOI: 10.4236/iim.2011.32007
Abstract: In this paper we present the main phases of the BP-M* methodology and its application to a care pathway for patients in the Oncology Division of a large hospital, to evaluate pros and cons of different drug administration modalities and the impact of these modalities to the organizational process. BP-M* has been developed for the manufacturing sector but the relevance of business modeling, analysis and reorganization is not restricted to a specific sector. The aim of this work is to show its application to a real life study of a complex process in the health sector.
Silicone Band in the Surgical Treatment of Manifest Exotropia  [PDF]
Lelio Sabetti, Antonio Berarducci, Domenico Di Lodovico
Open Journal of Ophthalmology (OJOph) , 2013, DOI: 10.4236/ojoph.2013.31001

Purpose: A silicone band was sutured anteriorly to the edge of the lateral rectus muscle neotendon during recession surgery in order to reduce and delay the reoccurrence after exotropia surgery. Methods: Collected data of 12 patients (8 males and 4 females), aged 7 - 54 years with diagnosis of constant manifest exotropia and mean angle deviation in primary position of 15,04o(sd 1,18) for near and of 13,23o (sd 0,71) for distance. All patients underwent surgical treatment consisting of lateral rectus recession and silicone band apposition in correspondence to the anterior edge of the lateral rectus muscle neotendon. Results: A substantial reduction of the mean angle deviation was observed in all patients after surgery. No adverse bandrelated effects were detected. Conclusion: The silicone band in the surgical treatment of manifest exotropia could be a valuable aid in delaying the relapse thanks to its physical and structural features and to its biocompatibility.

Business Process Analysis and Simulation: The Contact Center of a Public Health and Social Information Office  [PDF]
Antonio Di Leva, Emilio Sulis, Manuela Vinai
Intelligent Information Management (IIM) , 2017, DOI: 10.4236/iim.2017.95010
Abstract: This article proposes a framework, called BP-M* which includes: 1) a methodology to analyze, engineer, restructure and implement business processes, and 2) a process model that extends the process diagram with the specification of resources that execute the process activities, allocation policies, schedules, times of activities, management of queues in input to the activities and workloads so that the same model can be simulated by a discrete event simulator. The BP-M* framework has been applied to a real case study, a public Contact Center which provides different typologies of answers to users’ requests. The simulation allows to study different system operating scenarios (“What-If” analysis) providing useful information for analysts to evaluate restructuring actions.
Single Amino Acid Substitutions in the Chemotactic Sequence of Urokinase Receptor Modulate Cell Migration and Invasion
Katia Bifulco, Immacolata Longanesi-Cattani, Paola Franco, Vincenzo Pavone, Pietro Mugione, Gioconda Di Carluccio, Maria Teresa Masucci, Claudio Arra, Giuseppe Pirozzi, Maria Patrizia Stoppelli, Maria Vincenza Carriero
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0044806
Abstract: The receptor for urokinase-type plasminogen activator (uPAR) plays an important role in controlling cell migration. uPAR binds urokinase and vitronectin extracellular ligands, and signals in complex with transmembrane receptors such as Formyl-peptide Receptors (FPR)s and integrins. Previous work from this laboratory has shown that synthetic peptides, corresponding to the uPAR88–92 chemotactic sequence, when carrying the S90P or S90E substitutions, up- or down-regulate cell migration, respectively. To gain mechanistic insights into these opposite cell responses, the functional consequences of S90P and S90E mutations in full-length uPAR were evaluated. First, (HEK)-293 embryonic kidney cells expressing uPARS90P exhibit enhanced FPR activation, increased random and directional cell migration, long-lasting Akt phosphorylation, and increased adhesion to vitronectin, as well as uPAR/vitronectin receptor association. In contrast, the S90E substitution prevents agonist-triggered FPR activation and internalization, decreases binding and adhesion to vitronectin, and inhibits uPAR/vitronectin receptor association. Also, 293/uPARS90P cells appear quite elongated and their cytoskeleton well organized, whereas 293/uPARS90E cells assume a large flattened morphology, with random orientation of actin filaments. Interestingly, when HT1080 cells co-express wild type uPAR with uPAR S90E, the latter behaves as a dominant-negative, impairing uPAR-mediated signaling and reducing cell wound repair as well as lung metastasis in nude mice. In contrast, signaling, wound repair and in vivo lung metastasis of HT1080 cells bearing wild type uPAR are enhanced when they co-express uPARS90P. In conclusion, our findings indicate that Ser90 is a critical residue for uPAR signaling and that the S90P and S90E exert opposite effects on uPAR activities. These findings may be accommodated in a molecular model, in which uPARS90E and uPARS90P are forced into inactive and active forms, respectively, suggesting important implications for the development of novel drugs targeting uPAR function.
Vesicourethral anastomosis facilitated by a new disposable instrument
Di Piero, Antonio C.;
International braz j urol , 2004, DOI: 10.1590/S1677-55382004000400012
Abstract: the author presents a prototype of a disposable device that enables, in one single movement, the passing of all suture stitches in the urethral stump that will be anastomosed to the bladder or to a neobladder, with the advantage of a regular distribution of these stitches around the urethral circumference. in tests with animals, the device showed to be easily applicable, effective and safe.
Corchete y curvatura
Di Scala,Antonio J.;
Revista Colombiana de Matemáticas , 2005,
Abstract: the first part of this article presents the definition of lie bracket related to commuting flows of vector fields. in the second part, basic definitions and of connections and curvature are given in order to emphasize the link between lie brackets and curvature. finally, by using locally-defined connections, we give a short and original proof of a classical theorem of beltrami. the article is addressed to a non specialist in local differential geometry.
A atualidade da vis?o de Ab'Sáber
Mauro, Claudio Antonio Di;
Sociedade & Natureza , 2012, DOI: 10.1590/S1982-45132012000100002
Abstract: this paper turns itself to study the scientific work of professor aziz nacib ab'saber, at least in three aspects: 1) the geomorphology and paleoclimate evolution in the tertiary and quaternary, when the author acknowledges that the physiological studies of landscapes, although essential to the geomorpho logists'objectives, may be clarified only at the expense of markedly interdisciplinary research; 2) climate change processes, which are ignored in current knowledge, and the heritage gained over the history of the earth, to plan carefully, actions that promote societies in the pursuit of a "development"; 3) the s?o paulo' urban site, in the middle of last century, when, in less than 15 years, the town that and grew up in the hills, and hills had chosen as his ideal topography site, down to the plains, occupying sectors and clods newly emptied by the works of the energy company "light". the contributions were originally prepared under the geomorphological perspective, had, in their essence, the geographical view of the world citizen.
Corchete y curvatura
Antonio J. Di Scala
Revista Colombiana de Matemáticas , 2005,
Abstract: La primera parte del artículo presenta al corchete de Lie asociado al problema de la comutatividad de dos flujos. En la segunda parte se introducen las definiciones básicas de conexión y curvatura en fibrados vectoriales, subrayando la relación corchete-curvatura. Finalmente, usando conexiones afines localmente definidas, se da una demostración original y sencilla de un teorema de Eugenio Beltrami. Este artículo apunta a un lector no especialista (e.g. un estudiante de doctorado en matemática o física, etc) en geometría diferencial local. The first part of this article presents the definition of Lie Bracket related to commuting flows of vector fields. In the second part, basic definitions and of connections and curvature are given in order to emphasize the link between Lie Brackets and curvature. Finally, by using locally-defined connections, we give a short and original proof of a classical theorem of Beltrami. The article is addressed to a non specialist in local differential geometry.
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