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Search Results: 1 - 10 of 31785 matches for " Anselm Chi-Wai Lee "
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Unusual hematologic disease affecting Caucasian children traveling to Southeast Asia: acquired platelet dysfunction with eosinophilia
Anselm Chi-Wai Lee
Hematology Reports , 2012, DOI: 10.4081/hr.2012.e5
Abstract: An 11-year-old American boy was staying with his family in Indonesia. He presented with a 5-month history of recurrent bruises and ecchymosis. A clinical diagnosis of acquired platelet dysfunction with eosinophilia was made when his full blood counts showed hypereosinophilia (7.4×10 9/L) with normal platelet count and gray platelets under the microscope. The diagnosis was supported by abnormal platelet aggregation tests consistent with a storage pool disorder. The bleeding symptoms and eosinophilia resolved a month later with a full course of antihelminthic therapy. Hematologists should be aware of this unusual disease in travelers returning from the Southeast Asia.
Hyper-reactive malarial splenomegaly and splenic infarct in a caucasian toddler
Anselm Chi-Wai Lee
Infectious Disease Reports , 2011, DOI: 10.4081/idr.2011.e13
Abstract: A 4-year-old boy from the United States had been staying in Indonesia for five months when he presented with fever, severe lethargy, progressive weight loss, and abdominal distension. He was first diagnosed with Plasmodium vivax infection in Indonesia and received treatment with chloroquine. However, his condition continued to deteriorate and he required erythrocyte transfusion for severe anemia. Three weeks into his illness, he was found to have low parasitemia with Plasmodium falciparum with massive hepatosplenomegaly in Singapore. A splenic infarct was also documented on computed tomography. Treatment with atovaquone-proguanil resulted in stabilization of the hemoglobin level and rapid reduction in splenic size, with clearance of malarial parasites from the bloodstream. Although reported typically in adult tropical residents, hyper-reactive malarial splenomegaly may occasionally be found in the pediatric traveler. Clinicians receiving children returning from the tropical regions should be aware of this potentially life-threatening complication of partially treated malaria.
Dactinomycin-induced Hepatic Sinusoidal Obstruction Syndrome Responding to Treatment with N-acetylcysteine
Anselm Chi-wai Lee, Peter Yu-tang Goh
Journal of Cancer , 2011,
Abstract: Hepatic sinusoidal obstruction syndrome is commonly described in pediatric oncology as a complication of chemotherapy. It has also been occasionally reported in adult cancer patients. Treatment is largely supportive with fluid restriction. A 16-month-old girl with stage II Wilms tumor receiving post-nephrectomy chemotherapy with dactinomycin and vincristine developed hepatic sinusoidal obstruction syndrome with painful hepatomegaly, ascites with significant weight gain, grossly deranged liver function, severe thrombocytopenia, and reversal of blood flow in the portal vein on Doppler sonography. Treatment with N-acetylcysteine was followed by complete resolution of clinical signs and amelioration of laboratory abnormalities within 72 hours of treatment. N-acetylcysteine is a safe and probably an effective treatment for dactinomycin-induced hepatic sinusoidal obstructive syndrome.
Food-borne bacteremic illnesses in febrile neutropenic children
Anselm Chi-wai Lee,Nellie Dawn Siao-ping Ong
Hematology Reports , 2011, DOI: 10.4081/hr.2011.e11
Abstract: Bacteremia following febrile neutropenia is a serious complication in children with malignancies. Preventive measures are currently targeted at antimicrobial prophylaxis, amelioration of drug-induced neutropenia, and nosocomial spread of pathogens, with little attention to community-acquired infections. A retrospective study was conducted at a pediatric oncology center during a 3-year period to identify probable cases of food-borne infections with bacteremia. Twenty-one bacteremic illnesses affecting 15 children receiving chemotherapy or hematopoietic stem cell transplantation were reviewed. Three (14%) episodes were highly suspected of a food-borne origin: a 17-year-old boy with osteosarcoma contracted Sphingomonas paucimobilis septicemia after consuming nasi lemak bought from a street hawker; a 2-year-old boy with acute lymphoblastic leukemia developed Chryseobacterium meningosepticum septicemia after a sushi dinner; a 2-year-old girl was diagnosed with acute lymphoblastic leukemia and Lactobacillus bacteremia suspected to be of probiotic origin. All of them were neutropenic at the time of the infections and the bacteremias were cleared with antibiotic treatment. Food-borne sepsis may be an important, but readily preventable, cause of bloodstream infections in pediatric oncology patients, especially in tropical countries with an abundance of culinary outlets.
Chronic ulcerative gastroduodenitis as a first gastrointestinal manifestation of Hermansky-Pudlak syndrome in a 10-year-old child
Anselm Chi-Wai Lee, Kin-Hung Poon, Wing-Hong Lo, Lap-Gate Wong
World Journal of Gastroenterology , 2008,
Abstract: A 10-year-old Chinese boy who had a history of congenital thrombocytopathy presented with severe iron deficiency anemia secondary to chronic gastric inflammation and duodenal ulcerations. Subtle oculocutaneous albinism led to the finding of diminished dense bodies in the platelets under electron microscopy, hence the diagnosis of Hermansky-Pudlak syndrome (HPS). Biopsies from the stomach and duodenum revealed a lymphocytic infiltration in the submucosa, but H pylori infection was absent. The gastroduodenitis responded to the treatment with omeprazole while iron deficiency anemia was corrected by oral iron therapy. HPS is a rare cause of congenital bleeding disorder with multisystemic manifestations. Upper gastrointestinal involvement is rare and should be distinguished from a mere manifestation of the bleeding diathesis.
A Numerical Study of Boson Stars
Chi-Wai Lai
Physics , 2004,
Abstract: We present a numerical study of general relativistic boson stars in both spherical symmetry and axisymmetry. We consider both time-independent problems, involving the solution of equilibrium equations for rotating boson stars, and time-dependent problems, focusing on black hole critical behaviour associated with boson stars. The study of the critical phenomena that arise at the threshold of black hole formation has been a subject of intense interest among relativists and applied mathematicians over the past decade. Type I critical phenomena were previously observed in the dynamics of spherically symmetric boson stars by Hawley and Choptuik. We extend this work and show that, contrary to previous claims, the subcritical end-state is well described by a stable boson star executing a large amplitude oscillation with a frequency in good agreement with that predicted for the fundamental normal mode of the end-state star from linear perturbation theory. We then extend our studies of critical phenomena to the axisymmetric case, studying two distinct classes of parametrized families of initial data whose evolution generates families of spacetimes that ``interpolate'' between those than contain a black hole and those that do not. In both cases we find strong evidence for a Type I transition at threshold, and are able to demonstrate scaling of the lifetime for near-critical configurations of the type expected for such a transition. This is the first time that Type I critical solutions have been simulated in axisymmetry.
Property $(T)$ and strong Property $(T)$ for unital $C^*$-algebras
Chi-Wai Leung,Chi-Keung Ng
Mathematics , 2009,
Abstract: In this paper, we will give a thorough study of the notion of Property $(T)$ for $C^*$-algebras (as introduced by M.B. Bekka in \cite{Bek-T}) as well as a slight stronger version of it, called "strong property $(T)$" (which is also an analogue of the corresponding concept in the case of discrete groups and type $\rm II_1$-factors). More precisely, we will give some interesting equivalent formulations as well as some permanence properties for both property $(T)$ and strong property $(T)$. We will also relate them to certain $(T)$-type properties of the unitary group of the underlying $C^*$-algebra.
Invariant ideals of twisted crossed products
Chi-Wai Leung,Chi-Keung Ng
Mathematics , 2002,
Abstract: We prove a result concerning the inclusion of non-trivial invariant ideals inside non-trivial ideals of a twisted crossed product. We will also give results concerning the primeness and simplicity of crossed products of twisted actions of locally compact groups on $C^*$-algebras.
Berkovich spectra of elements in Banach Rings
Chi-Wai Leung,Chi-Keung Ng
Mathematics , 2014,
Abstract: Adapting the notion of the spectrum $\Sigma_a$ for an element $a$ in an ultrametric Banach algebra (as defined by Berkovich), we introduce and briefly study the Berkovich spectrum $\sigma^{Ber}_R(u)$ of an element $u$ in a Banach ring $R$. This spectrum is a compact subset of the affine analytic space $A_Z^1$ over $Z$, and the later can be identified with the "equivalence classes" of all elements in all complete valuation fields. If $R$ is generated by $u$ as a unital Banach ring, then $\sigma^{Ber}_R(u)$ coincides with the spectrum of $R$ (as defined by Berkovich). If $R$ is a unital complex Banach algebra, then $\sigma^{Ber}_R(u)$ is the "folding up" of the usual spectrum $\sigma_B(u)$ alone the real axis. For a non-Archimedean complete valuation field $k$ and an infinite dimensional ultrametric $k$-Banach space $E$ with an orthogonal base, if $u\in L(E)$ is a completely continuous operator, we show that many different ways to define the spectrum of $u$ give the same compact set $\sigma^{Ber}_{L(E)}(u)$. As an application, we give a lower bound for the valuations of the zeros of the Fredholm determinant $\det(1- t\cdot u)$ (as defined by Serre) in complete valuation field extensions of $k$. Using this, we give a concrete example of a completely continuous operator whose Fredholm determinant does not have any zero in any complete valuation field extension of $k$.
Complementary and alternative medicine use among older Australian women - a qualitative analysis
Deirdre McLaughlin, Chi-Wai Lui, Jon Adams
BMC Complementary and Alternative Medicine , 2012, DOI: 10.1186/1472-6882-12-34
Abstract: The women expressed a range of views on CAM which fell into three broad themes: "push" factors such as dissatisfaction with conventional health services, "pull" factors which emphasised the positive aspects of choice and self-care in health matters, and barriers to CAM use. Overall, the "push' factors did not play a major role in the decision to use CAM, rather this was driven by "pull" factors related to health care self-responsibility and being able to source positive information about types of CAM. A number of barriers were identified such as access difficulties associated with increased age, limited mobility and restricted transport options, as well as financial constraints.CAM use among older women was unlikely to be influenced by aspects of conventional health care ("push factors"), but rather was reflective of the personal beliefs of the women and members of their close social networks ("pull factors"). While it was also apparent that there were differences between the rural and urban women in their use of CAM, the reasons for this were mainly due to the difficulties inherent in accessing certain types of CAM in rural areas.The use of complementary and alternative medicines (CAM) among older adults is an emerging health issue [1]. A recent review has suggested that the increasing practice of CAM use among older people may be the result of several interacting trends. For example, the ageing of the global population has resulted in a concomitant focus on compression of morbidity. Additionally, increased consumer participation in health care and the rise of the anti-ageing movement has encouraged the advancement of technologies to slow or reverse the biological process of ageing [2]. However, we know very little about older peoples' experiences of using CAM and there has been criticism of the lack of gerontological perspectives within CAM research. In particular there has been a lack of attention to cultural, geographical and other determinants of CAM use in thi
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