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Sharing Resources in Educational Communities
Allison Littlejohn,Anoush Margarayn
International Journal of Emerging Technologies in Learning (iJET) , 2010, DOI: 10.3991/ijet.v5i2.857
Abstract: The paper explores the implications of mobility within educational communities for sharing and reuse of educational resources. The study begins by exploring individuals’ existing strategies for sharing and reusing educational resources within localised and distributed communities, with particular emphasis on the impact of geographic location on these strategies. The results indicate that the geographic distribution of communities has little impact on individuals’ strategies for resource management, since many individuals are communicating via technology tools with colleagues within a localised setting. The study points to few major differences in the ways in which individuals within the localised and distributed communities store, share and collaborate around educational resources. Moving beyond the view of individuals being statically involved in one or two communities, mobility across communities, roles and geographic location are formulated and illustrated through eight scenarios. The effects of mobility across these scenarios are outlined and a framework for future research into mobility and resource sharing within communities discussed.
Collective Learning in the Workplace: Important Knowledge Sharing Behaviours
Anoush Margarayn,Allison Littlejohn,Colin Milligan
International Journal of Advanced Corporate Learning (iJAC) , 2011, DOI: 10.3991/ijac.v4i4.1801
Abstract: In this paper we identify a set of learning practices adopted by knowledge workers as they learn at work. We examine how key knowledge sharing behaviours: consuming, connecting, creating and contributing knowledge, are associated with these learning practices. Each learning practice brings together a combination of these components to form a distinct learning pathway, providing a baseline for rethinking combinations of practices for more effective learning and development in the workplace.
The Influence of Naqshbandi Sheikhs on Educational Process of Timurid Era
Maasumeh Goodarzi,Aboulhassan Fayyaz Anoush
Asian Culture and History , 2013, DOI: 10.5539/ach.v5n1p79
Abstract: In the ninth century (A.H.) the number of Sufis and their sects increased due to Timurids’ attention to Sufis, and as a consequence convents (Khaneqa) became one of the most important economical and political centers. Excessive wealth and spiritual influence of Sufis leaders particularly Sheikhs of Naqshbani kingdom result in Sufism power being twice as much so that, Timurid kings and Sultans used their spiritual influence to legitimize their rules and tried not only to respect and honor them but also, to construct and operate their Khaneqas. Close relationship between Naqshbani’s leaders and Timurid Sultans had a great influence on most country’s affairs, particularly education and training as most of removal and installations in the field of educational affairs were under their views. In this survey, the impact of Naqshbandi’s Sheikhs on educational process during Timurid period was investigated and analyzed by citing library references and implementing analytical-descriptive method.
Predictors of Chronic Physical and Mental Quality of Life Following Traumatic Brain Injury  [PDF]
Shahrokh Yousefzade-Chabok, Sara Ramezani Kapourchali, Zoheir Reihanian, Ehsan Kazemnezhad Leili, Anoush Dehnadi Moghadam, Zahra Mohtasham Amiri
Health (Health) , 2014, DOI: 10.4236/health.2014.66069
Abstract: Objective and Background: This study aimed at determining the predictors of chronic physical and mental quality of life (QOL) in patients with traumatic brain injury (TBI) focusing on neuropsychological functions post trauma. Materials and Methods: This is a longitudinal study in which 257 patients having inclusion criteria were enrolled. Neuropsychological tasks including logical memory, verbal paired associates, visual memory, verbal expression, auditory comprehension, semantic judgment and semantic categories were implemented. The appearance of psychiatric disorder, Agnosia, Apraxia, Dysarthria and pragmatic linguistic disorder post trauma were evaluated at discharge. QOL was studied 6 months after injury by filling SF-36 questionnaire via phone interview with patients. Results: Appearance of some post-traumatic disorders including agnosia, pragmatic linguistic disorder and psychiatric disorder were significantly correlated to poor QOL. The final step of logistic regression model showed that TBI severity, verbal memory, auditory comprehension and semantic acceptability scores were predictors of unfavorable mental QOL as well as TBI severity, injury severity scale (ISS) score and multifocal lesions for unfavorable physical QOL. Discussion: Thus, it is recommended that clinicians choose medical therapeutic priorities to improve the verbal neuropsychological sequela and provide preliminaries for a chronic favorable mental QOL. Furthermore, to prevent of chronic unfavorable physical QOL, early care of organic injuries should be considered especially in patients with severe and multifocal TBI.
Loss of Tgif Function Causes Holoprosencephaly by Disrupting the Shh Signaling Pathway
Kenichiro Taniguchi,Anoush E. Anderson,Ann E. Sutherland,David Wotton
PLOS Genetics , 2012, DOI: 10.1371/journal.pgen.1002524
Abstract: Holoprosencephaly (HPE) is a severe human genetic disease affecting craniofacial development, with an incidence of up to 1/250 human conceptions and 1.3 per 10,000 live births. Mutations in the Sonic Hedgehog (SHH) gene result in HPE in humans and mice, and the Shh pathway is targeted by other mutations that cause HPE. However, at least 12 loci are associated with HPE in humans, suggesting that defects in other pathways contribute to this disease. Although the TGIF1 (TG-interacting factor) gene maps to the HPE4 locus, and heterozygous loss of function TGIF1 mutations are associated with HPE, mouse models have not yet explained how loss of Tgif1 causes HPE. Using a conditional Tgif1 allele, we show that mouse embryos lacking both Tgif1 and the related Tgif2 have HPE-like phenotypes reminiscent of Shh null embryos. Eye and nasal field separation is defective, and forebrain patterning is disrupted in embryos lacking both Tgifs. Early anterior patterning is relatively normal, but expression of Shh is reduced in the forebrain, and Gli3 expression is up-regulated throughout the neural tube. Gli3 acts primarily as an antagonist of Shh function, and the introduction of a heterozygous Gli3 mutation into embryos lacking both Tgif genes partially rescues Shh signaling, nasal field separation, and HPE. Tgif1 and Tgif2 are transcriptional repressors that limit Transforming Growth Factor β/Nodal signaling, and we show that reducing Nodal signaling in embryos lacking both Tgifs reduces the severity of HPE and partially restores the output of Shh signaling. Together, these results support a model in which Tgif function limits Nodal signaling to maintain the appropriate output of the Shh pathway in the forebrain. These data show for the first time that Tgif1 mutation in mouse contributes to HPE pathogenesis and provide evidence that this is due to disruption of the Shh pathway.
The Protective Effects of Garlic Extract Against Acetaminophen-Induced Oxidative Stress and Glutathione Depletion
M. Anoush,M.A. Eghbal,F. Fathiazad,H. Hamzeiy
Pakistan Journal of Biological Sciences , 2009,
Abstract: Acetaminophen, the most commonly sold over-the-counter antipyretic analgesic, is capable of causing severe and sometimes fatal hepatic damage in humans and experimental animals. The incidence of liver injury due to acetaminophen overdose, either with suicidal intent or by accident, is increasing. Garlic is among those medicinal plants famous for its different health protective effects. In this study, the protective effects of garlic extract on acute acetaminophen-induced liver injury were investigated using freshly isolated rat hepatocytes. The hepatocytes were isolated from Sprague-Dawley male rats by a two step collagenase model. Formation of Reactive Oxygen Species (ROS) and Glutathione (GSH) depletion were studied after addition of acetaminophen to cell suspensions. The effects of garlic extract on prevention of ROS formation as well as GSH depletion was investigated and compared with the effects of N-Acetyl Cysteine (NAC) as the standard treatment. Reactive oxygen species formation was assessed by a spectrofluorometry method and garlic extract was shown to be as effective as NAC in decreasing ROS formation induced by acetaminophen. Glutathione (GSH) levels of hepatocytes were determined using HPLC. Garlic extract was effective in preventing GSH depletion significantly (p<0.05). It is concluded that garlic extract has an antioxidant effect and can protect hepatocytes from GSH depletion following NAPQI production.
A proposal for continuous loading of an optical dipole trap with magnetically guided ultra cold atoms
Anoush Aghajani-Talesh,Markus Falkenau,Axel Griesmaier,Tilman Pfau
Physics , 2009, DOI: 10.1088/0953-4075/42/24/245302
Abstract: The capture of a moving atom by a non-dissipative trap, such as an optical dipole trap, requires the removal of the excessive kinetic energy of the atom. In this article we develop a mechanism to harvest ultra cold atoms from a guided atom beam into an optical dipole trap by removing their directed kinetic energy. We propose a continuous loading scheme where this is accomplished via deceleration by a magnetic potential barrier followed by optical pumping to the energetically lowest Zeeman sublevel. We theoretically investigate the application of this scheme to the transfer of ultra cold chromium atoms from a magnetically guided atom beam into a deep optical dipole trap. We discuss the realization of a suitable magnetic field configuration. Based on numerical simulations of the loading process we analyze the feasibility and efficiency of our loading scheme.
Demographic Characteristics of Patients and Causes Leading to Chronic Renal Failure in Children Admitted to Mashhad Children Hospital  [PDF]
Anoush Azarfar, Mohammad Esmaeeli, Yalda Ravanshad, Mitra Naseri, Shapour Badiee Aval, Fatemeh Ghanee Sharbaf, Sahar Ravanshad, Hassan Mehrad-Majd, Zohreh Mohammadi
Open Journal of Nephrology (OJNeph) , 2017, DOI: 10.4236/ojneph.2017.72006
Abstract: Background: An irreversible renal function impairment is called chronic renal failure (CRF) which finally leads to the “end-stage renal disease” (ESRD) and requires renal replacement therapies. The aim of this study is to evaluate the incidence, prevalence of epidemiological indicators (age, sex), and causes of chronic renal failure in children in Mashhad (one of the big cities of Iran). Methods: This is a cross-sectional study that was conducted on patients’ records over a seven-year period (2008-2014) in Doctor Sheikh Children’s Hospital of Mashhad. The inclusion criteria were all children under 20 years old diagnosed with ESRD, with a GFR less than 15 ml/min/1.73 m2 who were referred to the hospital during the study period. Patients’ information, such as age, gender, onset of dialysis, causes of constructing renal failure, and positive or negative antigen of hepatitis B was extracted from their records. Data were analyzed using SPSS 16 software. Results: A total of 326 patients were studied, of which, 56.4% were male. 45.1% were from 7 to 18 years. 56.4% of patients were on hemodialysis and others were on peritoneal dialysis. The most common cause of chronic renal failure in the study was respectively reflux nephropathy (32.9%), nephrotic syndrome (8.9%), neurogenic bladder (5.5%), stones (2.5%), glomerulopathy (2.1%) and cystinosis (1.5%) and (20.9%) had unknown cause. During the 7-year period of study considering the treatment outcomes, 69.3% of patients needed to continue the dialysis; 10.4% underwent transplantation; 10.4% unfortunately died despite of treatment and 1.5% were cured. Conclusions: It is hoped that considering the clinical symptoms of children with chronic renal failure and the diagnosis of the cause, we can reduce complications of the disease with a quick diagnosis and treatment, as well as appropriate follow-up.
Laser cooling of a magnetically guided ultra cold atom beam
Anoush Aghajani-Talesh,Markus Falkenau,Valentin V. Volchkov,Leah E. Trafford,Tilman Pfau,Axel Griesmaier
Physics , 2010, DOI: 10.1088/1367-2630/12/6/065018
Abstract: We report on the transverse laser cooling of a magnetically guided beam of ultra cold chromium atoms. Radial compression by a tapering of the guide is employed to adiabatically heat the beam. Inside the tapered section heat is extracted from the atom beam by a two-dimensional optical molasses perpendicular to it, resulting in a significant increase of atomic phase space density. A magnetic offset field is applied to prevent optical pumping to untrapped states. Our results demonstrate that by a suitable choice of the magnetic offset field, the cooling beam intensity and detuning, atom losses and longitudinal heating can be avoided. Final temperatures below 65 microkelvin have been achieved, corresponding to an increase of phase space density in the guided beam by more than a factor of 30.
A Femtosecond Nanometer Free Electron Source
Peter Hommelhoff,Yvan Sortais,Anoush Aghajani-Talesh,Mark A. Kasevich
Physics , 2005, DOI: 10.1103/PhysRevLett.96.077401
Abstract: We report a source of free electron pulses based on a field emission tip irradiated by a low-power femtosecond laser. The electron pulses are shorter than 70 fs and originate from a tip with an emission area diameter down to 2 nm. Depending on the operating regime we observe either photofield emission or optical field emission with up to 200 electrons per pulse at a repetition rate of 1 GHz. This pulsed electron emitter, triggered by a femtosecond oscillator, could serve as an efficient source for time-resolved electron interferometry, for time-resolved nanometric imaging and for synchrotrons.
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