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Search Results: 1 - 10 of 213530 matches for " Anna P. Goddu "
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Using Mobile Health to Support the Chronic Care Model: Developing an Institutional Initiative
Shantanu Nundy,Jonathan J. Dick,Anna P. Goddu,Patrick Hogan
International Journal of Telemedicine and Applications , 2012, DOI: 10.1155/2012/871925
Abstract:
Using Mobile Health to Support the Chronic Care Model: Developing an Institutional Initiative
Shantanu Nundy,Jonathan J. Dick,Anna P. Goddu,Patrick Hogan,Chen-Yuan E. Lu,Marla C. Solomon,Arnell Bussie,Marshall H. Chin,Monica E. Peek
International Journal of Telemedicine and Applications , 2012, DOI: 10.1155/2012/871925
Abstract: Background. Self-management support and team-based care are essential elements of the Chronic Care Model but are often limited by staff availability and reimbursement. Mobile phones are a promising platform for improving chronic care but there are few examples of successful health system implementation. Program Development. An iterative process of program design was built upon a pilot study and engaged multiple institutional stakeholders. Patients identified having a “human face” to the pilot program as essential. Stakeholders recognized the need to integrate the program with primary and specialty care but voiced concerns about competing demands on clinician time. Program Description. Nurse administrators at a university-affiliated health plan use automated text messaging to provide personalized self-management support for member patients with diabetes and facilitate care coordination with the primary care team. For example, when a patient texts a request to meet with a dietitian, a nurse-administrator coordinates with the primary care team to provide a referral. Conclusion. Our innovative program enables the existing health system to support a de novo care management program by leveraging mobile technology. The program supports self-management and team-based care in a way that we believe engages patients yet meets the limited availability of providers and needs of health plan administrators. 1. Introduction Despite the availability of effective treatments, chronic diseases are often poorly controlled and remain a leading cause of preventable morbidity and mortality and excess costs worldwide [1, 2]. Outcomes are generally worse for patients of lower socioeconomic status, including racial and ethnic minorities, who experience higher rates of disease and complications, lower quality and access to care, and limited health literacy and social support [3, 4]. The Chronic Care Model (CCM) has been proposed as a multicomponent intervention to improve chronic care [5, 6]. Self-management support is a cornerstone of CCM and has been linked to improved health outcomes in a range of chronic conditions [7]. Yet, in practice, self-management support programs are poorly reimbursed, difficult to scale, and often unavailable [8]. Payers and providers recognize the need for self-management support programs, but often lack the human or financial resources needed to adequately provide them [8]. Existing programs may not be suitable for racial and ethnic minorities and traditionally rely on one-on-one or group sessions, which are resource intensive [8, 9]. In addition,
Data envelopment analysis of randomized ranks
Sant'Anna, Annibal P.;
Pesquisa Operacional , 2002, DOI: 10.1590/S0101-74382002000200007
Abstract: probabilities and odds, derived from vectors of ranks, are here compared as measures of efficiency of decision-making units (dmus). these measures are computed with the goal of providing preliminary information before starting a data envelopment analysis (dea) or the application of any other evaluation or composition of preferences methodology. preferences, quality and productivity evaluations are usually measured with errors or subject to influence of other random disturbances. reducing evaluations to ranks and treating the ranks as estimates of location parameters of random variables, we are able to compute the probability of each dmu being classified as the best according to the consumption of each input and the production of each output. employing the probabilities of being the best as efficiency measures, we stretch distances between the most efficient units. we combine these partial probabilities in a global efficiency score determined in terms of proximity to the efficiency frontier.
Data envelopment analysis of randomized ranks
Sant'Anna Annibal P.
Pesquisa Operacional , 2002,
Abstract: Probabilities and odds, derived from vectors of ranks, are here compared as measures of efficiency of decision-making units (DMUs). These measures are computed with the goal of providing preliminary information before starting a Data Envelopment Analysis (DEA) or the application of any other evaluation or composition of preferences methodology. Preferences, quality and productivity evaluations are usually measured with errors or subject to influence of other random disturbances. Reducing evaluations to ranks and treating the ranks as estimates of location parameters of random variables, we are able to compute the probability of each DMU being classified as the best according to the consumption of each input and the production of each output. Employing the probabilities of being the best as efficiency measures, we stretch distances between the most efficient units. We combine these partial probabilities in a global efficiency score determined in terms of proximity to the efficiency frontier.
Envejecimiento y dolor Pain in the elderly
Anna Farr Pérez
Revista de la Sociedad Espa?ola del Dolor , 2008,
Abstract:
Approximation Theorems Related to the Coupon Collector's Problem
Anna Pósfai
Mathematics , 2010,
Abstract: This Ph.D. thesis concerns the version of the classical coupon collector's problem, when a collector samples with replacement a set of $n\ge 2$ distinct coupons so that at each time any one of the $n$ coupons is drawn with the same probability $1/n$. For a fixed integer $m\in\{0,1,...,n-1\}$, the coupon collector's waiting time $W_{n,m}$ is the random number of draws the collector performs until he acquires $n-m$ distinct coupons for the first time. The basic goal of the thesis is to approximate the distribution of the coupon collector's appropriately centered and normalized waiting time with well-known measures with high accuracy, and in many cases prove asymptotic expansions for the related probability distribution functions and mass functions. The approximating measures are chosen from five different measure families. Three of them -- the Poisson distributions, the normal distributions and the Gumbel-like distributions -- are probability measure families whose members occur as limiting laws in the limit theorems concerning $W_{n,m}$. The other two approximating measure families are certain compound Poisson distributions and Poisson--Charlier signed measures.
A Supplement to the Paper Poisson Approximation in a Poisson Limit Theorem Inspired by Coupon Collecting
Anna Pósfai
Mathematics , 2009,
Abstract: In this note we give a proof for the result stated as Theorem 4 in Poisson Approximation in a Poisson Limit Theorem Inspired by Coupon Collecting.
Irr1/Scc3 cohesin interacts with Rec8 in meiotic prophase of Saccharomyces cerevisiae  [PDF]
Agata Cena, Piotr Kowalec, Danuta P?ochocka, Anna Kurlandzka
Open Journal of Genetics (OJGen) , 2012, DOI: 10.4236/ojgen.2012.21001
Abstract: The meiotic cohesin complex of S. cerevisiae shares with the mitotic one the Irr1/Scc3, Smc1, and Smc3 subunits, while the meiosis-specific subunit Rec8 replaces mitotic subunit Scc1/Mcd1. We noticed earlier that the irr1-1 mutation (F658G) severely affected meiosis. The irr1 1/IRR1 cells were entering meiosis before having completed mitotic cell division. Using meiotic two-hybrid assay and co-immunoprecipitation we show that in cells arrested in pachytene due to a lack of a gene-regulatory factor Ndt80, the Irr1 protein interacts with Rec8p and the irr1-1 mutation abolishes this interaction. These findings indicate an important role of Irr1p in early stages of meiosis.
Genomic amplification of BCR/ABL1 and a region downstream of ABL1 in chronic myeloid leukaemia: a FISH mapping study of CML patients and cell lines
Anna Virgili, Elisabeth P Nacheva
Molecular Cytogenetics , 2010, DOI: 10.1186/1755-8166-3-15
Abstract: A duplication of the entire Ph chromosome with no further events involving the derivative 22 was found in 12 patients. In contrast, a sideline with either 1 or 2 isochromosomes of the Ph chromosome was identified in 6 patients but none of the cell lines. In one of the patients a translocation between the distal end of one arm of the isoderivative chromosome 22 and a third chromosome was revealed. 2 patients were found to carry marker structures harbouring high copy number gains of BCR/ABL1 fusion along with a variable part of 9q34 region downstream of ABL1 breakpoint, similarly to the markers present in the imatinib resistant cell line K562. We identified the following regions of amplification: 9q34.1 → q34.2 and 9q34.1 → qter, with a common minimum amplified region of 682 Kb. One of the patients had 5 BCR/ABL1 positive clones with variable level of 9q34 amplifications on a variety of structures, from an isoderivative 22 to tandem duplications.These data confirm that the intrachromosomal genomic amplification of BCR/ABL1 that occurs in some CML patients during disease progression also involves amplification of 9q34 gene-rich sequences downstream of ABL1 breakpoint. The variety of rearrangements identified in this relatively small cohort demonstrates that the Ph chromosome is not a stable structure but prone to further rearrangements during disease progression.Chronic myeloid leukaemia (CML) is a malignant pluripotent haematopoietic stem cell disease characterized by the expression of the BCR/ABL1 fusion gene, a constitutively activated tyrosine kinase which commonly results from the formation of the Philadelphia chromosome (Ph) after a t(9;22)(q34;q11) or related variant rearrangement [1]. Amplification of BCR/ABL1, as well as mutations of the fusion gene, has been shown to be associated with clinical resistance to imatinib therapy [2,3]. The blast phase of CML is characterized by acquisition of new cytogenetic abnormalities in 80% of the patients, the most common b
O conceito de natureza em A origem das espécies
Regner, Anna Carolina K. P.;
História, Ciências, Saúde-Manguinhos , 2001, DOI: 10.1590/S0104-59702001000400010
Abstract: the main issue in the theory of the origin of species through natural selection, according to charles darwin, is the attempt to enlighten the mystery of the origin of species, by showing how it takes place. when analyzing darwin's works, their different aspects and versions, we come across a certain view of nature that sustains and clarifies our search. in this article, we try to examine this view, as well as the epistemological and ontological support it gives to darwin's investigation and to his thesis that natural selection, among other factors, has been the most important 'means of modification', the prevailing 'power of changing, the 'principle' in nature according to which new species are originated. when analyzing the definitions and various connotations there are for 'nature' in his book, we find the necessary articulation between the two pillars 'nature' and 'natural selection', which is present in darwin's concept of 'struggle for existence' and reflected in the logical and conceptual structure of his work.
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