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Search Results: 1 - 10 of 1991 matches for " Ankrah Lennox-Mac "
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The Role of Human Herpesvirus Type-6 (HHV-6) in Convulsions Seen in Children at Korle-Bu Teaching Hospital, Accra  [PDF]
Ankrah Lennox-Mac, Adiku Theophilus, Badoe Eben, Kwamena William Coleman Sagoe, Anna Aba Kafintu-Kwashie, Makafui Seshie
Open Journal of Medical Microbiology (OJMM) , 2014, DOI: 10.4236/ojmm.2014.41009
Abstract:
Background: Since the isolation of HHV-6 in 1986, extensive investigation has revealed it to be ubiquitous and responsible for the majority of cases of a common febrile rash illness of infants known as roseola. Other clinical associations including seizure disorders, encephalitis and meningitis have also been stated in various publications. Objective: The aim of the study is to find out if there is any association between HHV-6 infection and the convulsions prevailing at the Child Health Department of the Korle-Bu Teaching Hospital, Accra-Ghana. Methods and Results: Children admitted into the Department of Child Health with episode of convulsions were recruited after informed consent had been sought from subjects. Cerebrospinal fluid (CSF) and Plasma were obtained from patients. PCR directed at the detection of the large tegument protein (LTP) gene in the SIE strain of the HHV-6 in Plasma and CSF from patients was done. The mean age of study subjects was 37.44 months with 53 (64.6%) being males. There was a significant relationship between the convulsions and fever (P < 0.05). Based on CSF characteristics gathered, viral infections may be the probable cause of the observed convulsions but not malaria or bacterial infections. None of the samples from the patients had evidence of HHV-6. Conclusion: The study was unable to establish HHV-6 infection in the CSF and Plasma of patients. What role if any HHV-6 has in convulsions seen in children or neurological diseases at large merits further studies. Other neurotropic viruses need to be investigated as possible causes for the convulsions.
Maternal Age, Low Birth Weight and Early Neonatal Death in Tertiary Hospital in the Volta Region of Ghana  [PDF]
Innocent Afeke, Lennox Mac-Ankrah, Ibrahim Jamfaru, Kokou H. Amegan-Aho, Hintermann Kobina Mbroh, Sylvester Y. Lokpo, Edem Obum, Delali Geni, Joseph Adu-Amankwaah, Verner N. Orish
Open Journal of Pediatrics (OJPed) , 2017, DOI: 10.4236/ojped.2017.74029
Abstract: Objectives: Current study sought to determine an association between Low Birth Weight (LBW) and early neonatal mortality at a resource limited country’s referral hospital and to determine relationship between maternal age and birth outcomes. Method: A retrospective study analyzing data on births in the Volta Regional Hospital, Ghana from the period of November 2011 to June 2016. A total of 8279 births were analyzed. Results: Results suggest that teenage mothers (8.60%) are more likely to give birth to pre-term babies than the elderly (6.60%) and the adult mothers (4.61%). LBW is highest among the teenage mothers (12.69%) followed by the elderly mothers (7.87%) and then the least among the adult mothers (6.48%). Extremely Low Birth Weight (ELBW) and Macrosomia births were more observed among the elderly mothers (0.90%; 2.17%) than the teenage (0.28%; 0.14%) and adult mothers (0.34%; 1.61%) respectively. Data suggest that 100% of the ELBW were pre-term birth, 88.28% Very Low Birth Weight (VLBW), 34.56% LBW and only 1.06% of the pre-term birth were with Normal Birth Weight (NBW). Death rate ranges from 50% for ELBW, 33.59% for VLBW, 8.22% for LBW, 5.43% for Macrosomia and 1.5% for NBW. However, death rate distribution among the various age groups was statistically not significant (
Malaria Control Mechanisms for Effective Healthcare Delivery in Ghana: The Use of Geographical Information Systems (GIS)  [PDF]
Lenos Koku Ankrah, Desmond Ayim-Aboagye, Franklin N. Glozah
Open Journal of Preventive Medicine (OJPM) , 2016, DOI: 10.4236/ojpm.2016.62008
Abstract: Malaria is a major health problem facing many tropical countries, including Ghana. The use of modern mechanisms to study environmental factors in malaria occurrence is imperative in malaria control efforts. The aim of this research is to investigate how malaria occurrence is influenced by environmental factors and how Geographical Information Systems (GIS) can be used as a mechanism for improving malaria control in healthcare delivery in Ghana. Environmental factors, elevation, daily temperature and daily rainfall were plotted against prevalence of M and S forms of mosquitoes using ArcGIS 10.1. Prevalence of Anopheles gambiae M was the highest at elevations of 0 m to 200 m and that of S was the highest at elevations between 200 m and 500 m. Prevalence of M was the highest at temperatures between 26.1°C - 27.6°C whilst that of S was the highest at temperatures of between 24.5°C and 26.0°C. Prevalence of M was the highest at rainfall between 10 mm and 35 mm and S was the highest at rainfall between 26 mm and 36 mm and beyond. M form was positively correlated with temperature and negatively with elevation and humidity. The S form was negatively associated with temperature and positively with elevation and rainfall. GIS models can combine with environmental data to estimate vector prevalence under environmental conditions and therefore its use is recommended in Ghana.
NPPF and Archaeology: A Discussion
Rob Lennox
Papers from the Institute of Archaeology , 2013, DOI: 10.5334/pia.398
Abstract: Flatman and Perring have demonstrated in this article that the NPPF has thus far engendered mixed emotions for those of us working in the historic environment sector, but they seem to suggest that the overriding sense is one of relief after a fearful consultation process; the stormy waters have died down and it looks like steady sailing ahead. However, perhaps the real problem lies in the fact that the promising winds of change have dropped too, and that our ship may be in danger of being becalmed.
Conservative treatment of unruptured Ectopic pregnancy in Jamaica  [PDF]
Horace Fletcher, Keisha Buchanan, Lennox Jacob
Open Journal of Obstetrics and Gynecology (OJOG) , 2011, DOI: 10.4236/ojog.2011.11002
Abstract: Medical treatment with methotrexate is now successfully replacing conservative surgical treatment in selected patients. We reviewed patients treated with methotrexate, compared to salpingectomy and salpingostomy between 1990 to 1995 and 2000 to 2003. For 1990-1995 there were 21 conservative surgical treatments (5.3% ectopic pregnancies). The ratio of ectopic to normal deliveries was 1:24. Medical treatment was done for 19 pregnancies (3.4% of ectopic pregnancies) for 2000 to 2003. During the period there was an ectopic rate of 1:16.8 births. Patients treated medically were similar to those treated surgically except that none reportedly having rebound tenderness and only 1/18 having an ultrasound scan showing a foetal heart and none with a gestational sac >4cm. In the medically treated group the success rate was 68% while in the surgically treated groups success was 100%. There was no significant difference in the parameters in the conservative surgical and medically treated groups
Numerical Accuracy of the Kiva4 Code under Different Ignition Timing on the Combustion Characteristics of Gasoline in a Spark Ignition Engine  [PDF]
Joseph Lungu, Lennox Siwale, Edwin Luwaya
Journal of Power and Energy Engineering (JPEE) , 2018, DOI: 10.4236/jpee.2018.611008
Abstract: The purpose of this work was to show that kiva4 is more accurate than kiva3vr2 under different ignition timings. The numerical accuracy of kiva4 was compared with the numerical results obtained by other researchers who used kiva3vr2 as the simulation code. The combustion characteristics of gasoline under different ignition timings are obtained using the kiva4 code. For achieving this, two cases were investigated; a complete engine cycle was successfully simulated using a four-valve pent-roof engine and a comparison was made with experimental results by other researchers. At a constant speed of 600 rpm, a BASF (Badische Anilin-und Soda Fabrik) octane rating engine-single cylinder was used where ignition timing was changed in the range of 4° BTDC to 18° BTDC. Kiva4 generates more accurate results than kiva3vr2. The experimental results were more in agreement with kiva4 than kiva3vr2 results. The average temperature and pressure in kiva4 were 640 K and 16.48 bars while in kiva3vr2 were 600 K and 14.83 bars, the peak temperature and pressure in kiva4 were 2316.3 K and 21.5 bars while in kiva3vr2 were 2171.5 K and 19.4 bars. The peak temperature and pressure increase with increasing spark advance until the most favorable instant time is determined. Best performance was achieved when the ignition time was set to 10 degrees before top dead center.
Toxins and Secretion Systems of Photorhabdus luminescens
Athina Rodou,Dennis O. Ankrah,Christos Stathopoulos
Toxins , 2010, DOI: 10.3390/toxins2061250
Abstract: Photorhabdus luminescens is a nematode-symbiotic, gram negative, bioluminescent bacterium, belonging to the family of Enterobacteriaceae.Recent studies show the importance of this bacterium as an alternative source of insecticides, as well as an emerging human pathogen. Various toxins have been identified and characterized in this bacterium. These toxins are classified into four major groups: the toxin complexes (Tcs), the Photorhabdus insect related (Pir) proteins, the “makes caterpillars floppy” (Mcf) toxins and the Photorhabdus virulence cassettes (PVC); the mechanisms however of toxin secretion are not fully elucidated. Using bioinformatics analysis and comparison against the components of known secretion systems, multiple copies of components of all known secretion systems, except the ones composing a type IV secretion system, were identified throughout the entire genome of the bacterium. This indicates that Photorhabdus luminescens has all the necessary means for the secretion of virulence factors, thus it is capable of establishing a microbial infection.
History and Philosophy of Science: a Phylogenetic approach
Lennox, James G.;
História, Ciências, Saúde-Manguinhos , 2001, DOI: 10.1590/S0104-59702001000400008
Abstract: in the aftermath of thomas kuhn's the structure of scientific revolutions, there was a great deal of discussion about the relationship between the history of science and the philosophy of science. a wider issue was at stake in these discussions: 'normativism' versus 'naturalism' in epistemology. if the history of science, at best, gives us reliable information about what actually occurred historically, how can it inform debates about such things as confirmation or explanation in philosophy of science? this essay makes a case for the centrality of historical investigation in the philosophy of science. i will defend what i term the 'phylogenetic' approach to the philosophy of science. i will argue that since the foundations and dominant methods of a particular scientific field are shaped by its history, studying that history can give us considerable insight into conceptual and methodological problems in a particular science. the case will be made both on general, philosophical grounds, and by compelling instantiation.
History and Philosophy of Science: a Phylogenetic approach
Lennox James G.
História, Ciências, Saúde-Manguinhos , 2001,
Abstract: In the aftermath of Thomas Kuhn's The structure of scientific revolutions, there was a great deal of discussion about the relationship between the History of Science and the Philosophy of Science. A wider issue was at stake in these discussions: 'normativism' versus 'naturalism' in Epistemology. If the History of Science, at best, gives us reliable information about what actually occurred historically, how can it inform debates about such things as confirmation or explanation in Philosophy of Science? This essay makes a case for the centrality of historical investigation in the Philosophy of Science. I will defend what I term the 'Phylogenetic' approach to the Philosophy of Science. I will argue that since the foundations and dominant methods of a particular scientific field are shaped by its history, studying that History can give us considerable insight into conceptual and methodological problems in a particular Science. The case will be made both on general, philosophical grounds, and by compelling instantiation.
Charles Darwin, Geologist by Sandra Herbert
James G. Lennox
Aestimatio : Critical Reviews in the History of Science , 2007,
Abstract:
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