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Search Results: 1 - 10 of 11725 matches for " Angela Meincke Melo "
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Dinamica de Sala de Aula: uma variável na aprendizagem
Reinoldo Marquezan,Angela Meincke Melo,Graciela F. Rodrigues,Daniele Noal
Revista Educa??o Especial , 2012, DOI: 10.5902/1984686x5005
Abstract: A dinamica da aprendizagem se dá através de intera es mútuas, nas quais alunos e professores estabelecem rela es sociais e afetivas. Na sala de aula essas rela es se orientam para promover e efetivar a aprendizagem formal. Neste artigo apresentamos os resultados da pesquisa que teve como objetivo interagir com o professor de modo intencional, subsidiando-o para aumentar as situa es de troca entre seus alunos. Primeiramente identificou-se a estrutura sócio-afetiva dos grupos, utilizando como instrumento o Teste Sociométrico. No segundo momento realizamos com os docentes, encontros nos quais abordou-se quest es referentes a dinamica de grupo e as concep es construtivistas de aprendizagem. Acreditamos que, conforme a Teoria Construtivista da aprendizagem, a intera o e as trocas entre os membros constituintes do grupo de sala de aula é fundamental para a aquisi o de uma aprendizagem significativa para os educandos. Palavras-chave: dinamica de grupo, aprendizagem, sala de aula.
DESIGN COM CRIAN AS: DA PRáTICA A UM MODELO DE PROCESSO
Amanda Meincke Melo,M. Cecília C. Baranauskas,Sílvia Cristina de Matos Soares
Revista Brasileira de Informática na Educa??o , 2009,
Abstract: Modelos, métodos e processos de design em geral têm considerado o sujeito como “usuário” de tecnologia criada para ele a partir de um modelo conceitual de “quem” é e “de que necessita” esse sujeito. Se essa é a realidade no mundo do adulto, mais ainda no caso de tecnologia construída para crian as. Nossa experiência em projetos de pesquisa envolvendo o design de ambientes educacionais com crian as tem mostrado oportunidades e limita es associadas ao design de tecnologia com o envolvimento de crian as no processo de design. Neste artigo, apresentamos um modelo de processo, centrado na participa o da crian a e comprometido com seus significados para elementos de design, derivado de nossa prática. Esta contribui o visa facilitar a sua apropria o por designers, desenvolvedores e outras partes interessadas no design e desenvolvimento de sistemas e ambientes virtuais para uso da crian a. O referencial teórico-metodológico utilizado tem bases no Design Participativo e na Semiótica Organizacional. As técnicas e os métodos que comp em este modelo de processo foram experimentados e adaptados de nossa prática anterior.
An Investigation of Stochastic Cooling in the Framework of Control Theory
O. Meincke
Physics , 1996,
Abstract: This report provides a description of unbunched beam stochastic cooling in the framework of control theory. The main interest in the investigation is concentrated on the beam stability in an active cooling system. A stochastic cooling system must be considered as a closed-loop, similar to the feedback systems used to damp collective instabilities. These systems, which are able to act upon themselves, are potentially unstable. The self-consistent solution for the beam motion is derived by means of a mode analysis of the collective beam motion. This solution yields a criterion for the stability of each collective mode. The expressions also allow for overlapping frequency bands in the beam spectrum and thus are valid over the entire frequency range. Having established the boundaries of stability in this way, the Fokker-Planck equation is used to describe the cooling process. This description does not include collective effects and thus a stable beam must be assumed. Hence the predictions about the cooling process following from the Fokker-Planck equation only make physical sense within the boundaries of beam stability. Finally it is verified that the parameters of the cooling system which give the best cooling results are compatible with the stability of the beam.
Comparison of RNA extraction methods from biofilm samples of Staphylococcus epidermidis
Angela Fran?a, Luís DR Melo, Nuno Cerca
BMC Research Notes , 2011, DOI: 10.1186/1756-0500-4-572
Abstract: RNA extracted using the different kits was evaluated for quantity, purity, integrity, and functionally. All kits were able to extract intact and functional total RNA from the biofilms generated from each S. epidermidis strain. The results demonstrated that the kit based on mechanical lysis and organic extraction (FastRNA? Pro Blue) was the only one that was able to isolate pure and large quantities of RNA. Normalized expression of the icaA virulence gene showed that RNA extracted with PureLink? had a significant lower concentration of icaA mRNA transcripts than the other kits tested.When working with complex samples, such as biofilms, that contain a high content extracellular polysaccharide and proteins, special care should be taken when selecting the appropriate RNA extraction system, in order to obtain accurate, reproducible, and biologically significant results. Among the RNA extraction kits tested, FastRNA? Pro Blue was the best option for both S. epidermidis biofilms used.Staphylococcus epidermidis, a normal inhabitant of normal human skin and mucosa, has recently emerged as a leading cause of biofilm-related infections, particularly, in patients with indwelling medical devices [1,2] due to its ability to adhere to abiotic surfaces and to form biofilms [2,3]. The quantification of specific messenger RNA (mRNA) from these biofilms is crucial to understanding the molecular mechanisms behind biofilm formation and maturation on the surface of medical devices. The success of any RNA-based analysis depends on the yield, purity, and integrity of the RNA [4,5]. However, different RNA extraction methods can yield RNA with varying levels of quality [6,7]. Currently, there are numerous methods for RNA extraction available, however there are only a few published studies comparing RNA extraction from biofilm samples [8-10]. Biofilm samples pose an increased problem to RNA extraction procedure mainly due to the presence of the extracellular matrix, which is estimated to comp
Gest?o Adaptativa: uma proposta para o gerenciamento de redes de inova??o
Melo, Maria Angela Campelo de;Agostinho, Marcia Cristina Esteves;
Revista de Administra??o Contemporanea , 2007, DOI: 10.1590/S1415-65552007000200006
Abstract: this paper proposes 'adaptive management' as an approach to manage innovation networks. built upon two related conceptual perspectives - the sociotechnical approach and the theory of complexity - , adaptive management confers greater adaptability to organizations by integrating planning and managing issues. initially, the structure of this methodology is presented, in terms of basic principles and a set of planning and managing actions. then, the methodology is used as a framework for analysis of two innovative networks cases, and its usefulness to the management of such organizational sets is discussed. finally, elements that suggest advantages of 'adaptive management' in comparison to conventional managerial approaches are presented. such elements contribute for speeding the collective learning process and stimulating the generation of community ties in innovation networks.
Evaluation of indirect susceptibility testing of Mycobacterium tuberculosis to the first- and second-line, and alternative drugs by the newer MB/BacT system
Barreto, Angela Maria Werneck;Araújo, Joselba Borges Melo;Medeiros, Reginalda Ferreira de Melo;Caldas, Paulo César de Souza;
Memórias do Instituto Oswaldo Cruz , 2003, DOI: 10.1590/S0074-02762003000600020
Abstract: in order to evaluate the organon teknika mb/bact system used for testing indirect susceptibility to the alternative drugs ofloxacin (oflo), amikacin (ami), and rifabutin (rif), and to the usual drugs of standard treatment regimes such as rifampin (rmp), isoniazid (inh), pyrazinamide (pza), streptomycin (sm), ethambutol (emb), and ethionamide (eth), cultures of clinical specimens from 117 patients with pulmonary tuberculosis under multidrug-resistant investigation, admitted sequentially for examination from 2001 to 2002, were studied. fifty of the mycobacterium tuberculosis cultures were inoculated into the gold-standard bactec 460 tb (becton dickinson) for studying resistance to ami, rif, and oflo, and the remaining 67 were inoculated into lowenstein jensen (lj) medium (the gold standard currently used in brazil) for studying resistance to rmp, inh, pza, sm, emb, and eth. we observed 100% sensitivity for ami (80.8-100), rif (80.8-100), and oflo (78.1-100); and 100% specificity for ami (85.4-100), rif (85.4-100), and oflo (86.7-100) compared to the bactec system. comparing the results obtained in lj we observed 100% sensitivity for rmp (80-100), followed by inh - 95% (81.8-99.1), emb - 94.7% (71.9-99.7), and 100% specificity for all drugs tested except for pza - 98.3 (89.5-99.9) at 95% confidence interval. the results showed a high level of accuracy and demonstrated that the fully automated, non-radiometric mb/bact system is indicated for routine use in susceptibility testing in public health laboratories.
Direct Sensitivity Test of the MB/BacT System
Barreto, Angela Maria Werneck;Araujo, Joselba Borges Melo;Medeiros, Reginalda Ferreira de Melo;Caldas, Paulo Cesar de Souza;
Memórias do Instituto Oswaldo Cruz , 2002, DOI: 10.1590/S0074-02762002000200021
Abstract: in order to evaluate the direct-method test of sensitivity to drugs used in the principal tuberculosis treatment regimes, in the organon teknika mb/bact system, we tested 50 sputum samples positive to microscopy taken from patients with pulmonary tuberculosis and with clinical indications for an antibiogram, admitted sequentially for examination during the routine of the reference laboratory. the material was treated v/v with 23% trisodium phosphate solution, incubated for 24 h at 35°c, and neutralized v/v with 20% monosodium phosphate solution. the material was then centrifuged and the sediment inoculated into flasks containing rifampin - 2 μg/ml, isoniazid - 0.2 μg/ml, pyrazinamide - 100 μg/ml, ethambutol - 2.5 μg/ml, ethionamide - 1.25 μg/ml, and streptomycin - 2 μg/ml. the tests were evaluated using the indirect method in the bactec 460 tb (becton dickinson) system as the gold standard. the results showed that the rifampin test performed best, i.e., 100% sensitivity at 95% confidence interval (82.2-100) and 100% specificity at 95% confidence interval (84.5-100), followed by isoniazid and pyrazinamide. in this experiment, 92% of the materials showed a final reading in 30 days; this period represents the time for primary isolation as well as the results of the sensitivity profile, and is within centers for disease control and prevention recommendations regarding time for performance of the antibiogram. the inoculated flasks showed no contamination during the experiment. the mb/bact is shown to be a reliable, rapid, fully automated nonradiometric system for the tuberculosis antibiogram.
Evaluation of indirect susceptibility testing of Mycobacterium tuberculosis to the first- and second-line, and alternative drugs by the newer MB/BacT system
Barreto Angela Maria Werneck,Araújo Joselba Borges Melo,Medeiros Reginalda Ferreira de Melo,Caldas Paulo César de Souza
Memórias do Instituto Oswaldo Cruz , 2003,
Abstract: In order to evaluate the Organon Teknika MB/BacT system used for testing indirect susceptibility to the alternative drugs ofloxacin (OFLO), amikacin (AMI), and rifabutin (RIF), and to the usual drugs of standard treatment regimes such as rifampin (RMP), isoniazid (INH), pyrazinamide (PZA), streptomycin (SM), ethambutol (EMB), and ethionamide (ETH), cultures of clinical specimens from 117 patients with pulmonary tuberculosis under multidrug-resistant investigation, admitted sequentially for examination from 2001 to 2002, were studied. Fifty of the Mycobacterium tuberculosis cultures were inoculated into the gold-standard BACTEC 460 TB (Becton Dickinson) for studying resistance to AMI, RIF, and OFLO, and the remaining 67 were inoculated into Lowenstein Jensen (LJ) medium (the gold standard currently used in Brazil) for studying resistance to RMP, INH, PZA, SM, EMB, and ETH. We observed 100% sensitivity for AMI (80.8-100), RIF (80.8-100), and OFLO (78.1-100); and 100% specificity for AMI (85.4-100), RIF (85.4-100), and OFLO (86.7-100) compared to the BACTEC system. Comparing the results obtained in LJ we observed 100% sensitivity for RMP (80-100), followed by INH - 95% (81.8-99.1), EMB - 94.7% (71.9-99.7), and 100% specificity for all drugs tested except for PZA - 98.3 (89.5-99.9) at 95% confidence interval. The results showed a high level of accuracy and demonstrated that the fully automated, non-radiometric MB/BacT system is indicated for routine use in susceptibility testing in public health laboratories.
Direct Sensitivity Test of the MB/BacT System
Barreto Angela Maria Werneck,Araujo Joselba Borges Melo,Medeiros Reginalda Ferreira de Melo,Caldas Paulo Cesar de Souza
Memórias do Instituto Oswaldo Cruz , 2002,
Abstract: In order to evaluate the direct-method test of sensitivity to drugs used in the principal tuberculosis treatment regimes, in the Organon Teknika MB/BacT system, we tested 50 sputum samples positive to microscopy taken from patients with pulmonary tuberculosis and with clinical indications for an antibiogram, admitted sequentially for examination during the routine of the reference laboratory. The material was treated v/v with 23% trisodium phosphate solution, incubated for 24 h at 35°C, and neutralized v/v with 20% monosodium phosphate solution. The material was then centrifuged and the sediment inoculated into flasks containing Rifampin - 2 μg/ml, Isoniazid - 0.2 μg/ml, Pyrazinamide - 100 μg/ml, Ethambutol - 2.5 μg/ml, Ethionamide - 1.25 μg/ml, and Streptomycin - 2 μg/ml. The tests were evaluated using the indirect method in the BACTEC 460 TB (Becton Dickinson) system as the gold standard. The results showed that the Rifampin test performed best, i.e., 100% sensitivity at 95% Confidence Interval (82.2-100) and 100% specificity at 95% Confidence Interval (84.5-100), followed by Isoniazid and Pyrazinamide. In this experiment, 92% of the materials showed a final reading in 30 days; this period represents the time for primary isolation as well as the results of the sensitivity profile, and is within Centers for Disease Control and Prevention recommendations regarding time for performance of the antibiogram. The inoculated flasks showed no contamination during the experiment. The MB/BacT is shown to be a reliable, rapid, fully automated nonradiometric system for the tuberculosis antibiogram.
Women entrepreneurship in Romania
Angela ON
Revista Romana de Economie , 2011,
Abstract: Considering entrepreneurship the domain with the greatest potential for creativity and innovation, any investigation on this field is recommended, in order to reveal new aspects that can influence the small enterprises development. From this point of view, female entrepreneurship represents an important source of innovation, only partially exploited or even forgotten.
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