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Search Results: 1 - 10 of 19986 matches for " André Michaud "
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The Hydrogen Atom Fundamental Resonance States  [PDF]
André Michaud
Journal of Modern Physics (JMP) , 2018, DOI: 10.4236/jmp.2018.95067
Abstract: In the 1920’s, Louis de Broglie’s observation that the integer sequence that could be related to the interference patterns produced by the various electromagnetic energy quanta emitted by hydrogen atoms was identical to those of very well known classical resonance processes, made him conclude that electrons were captive in resonance states within atoms. This led Schr?dinger to propose a wave function to represent these resonance states that still have not been reconciled with the electromagnetic properties of electrons. This article is meant to identify and discuss the electromagnetic harmonic oscillation properties that the electron must possess as a resonator in order to explain the resonance volume described by the wave function, as well as the electromagnetic interactions between the elementary charged particles making up atomic structures that could explain electronic and nucleonic orbitals stability. An unexpected benefit of the expanded space geometry required to establish these properties and interactions is that the fundamental symmetry requirement is respected by structure for all aspects of the distribution of energy within electromagnetic quanta.
The Mechanics of Conceptual Thinking  [PDF]
André Michaud
Creative Education (CE) , 2019, DOI: 10.4236/ce.2019.102028
Abstract: Description of the mechanics of conceptual thinking?that?stems?from interaction sequences between the limbic system and the verbal areas of the neocortex. Description of the rise of the attention level to full active awareness when a feeling of uneasiness due to a verbal stimulus is triggered by the amygdala, followed by an active cogitation process involving the verbal areas of the neocortex, ending in the strengthening in the neocortex by the hippocampus of a synaptic network corresponding to a modified verbal sequence that removes or reduces the feeling of uneasiness that initiated the sequence. Description of the generalization abilitythat?emerges from the use of articulated languages, acquired by education, from which conceptual thinking andalso?the collectively intelligible mathematical language emerge that also develops to various degrees in some individuals by education. Description of the mathematical thinking mode, about?whose engrams have been located in the neocortex in areas that do not overlap the verbal areas.
Galactans: an overview of their most important sourcing and applications as natural polysaccharides
Delattre, Cedric;Fenoradosoa, Taratra Andrée;Michaud, Philippe;
Brazilian Archives of Biology and Technology , 2011, DOI: 10.1590/S1516-89132011000600002
Abstract: since last decades, lot of biological and rheological properties of polysaccharides and oligosaccharides were described. among them, galactans and more especially sulfated galactans from seaweeds have shown interesting and specific properties not only as texturing agents but also as biological active compounds on several organisms. this class of polysaccharides includes classical sulfated galactans extracted from seaweeds and classified as agar and carrageenans. however, some galactans are more complex and their specific structural features have been characterized after their extraction from terrestrial plants, seaweeds but also animals and microoragnisms. this review catalogues the origins, structural characteristics and potentialities of these polysaccharides and their oligosaccharides derivatives.
Challenging the “Inoffensiveness” of Regular Cannabis Use by Its Associations with Other Current Risky Substance Use—A Census of 20-Year-Old Swiss Men
Gerhard Gmel,Jacques Gaume,Carole Willi,Pierre-André Michaud,Jacques Cornuz,Jean-Bernard Daeppen
International Journal of Environmental Research and Public Health , 2010, DOI: 10.3390/ijerph7010046
Abstract: 3,537 men enrolling in 2007 for mandatory army recruitment procedures were assessed for the co-occurrence of risky licit substance use among risky cannabis users. Risky cannabis use was defined as at least twice weekly; risky alcohol use as 6+ drinks more than once/monthly, or more than 20 drinks per week; and risky tobacco use as daily smoking. Ninety-five percent of all risky cannabis users reported other risky use. They began using cannabis earlier than did non-risky users, but age of onset was unrelated to other risky substance use. A pressing public health issue among cannabis users stems from risky licit substance use warranting preventive efforts within this age group.
The Effects of Assessment: a Reflection from within the Economic Worldview in Education
Olivier Michaud
Analytic Teaching and Philosophical Praxis , 2010,
Abstract: In a seminar held in my university last fall on education policy research, I was, like many of my colleagues, astonished at the dominance of the economic worldview in the shaping of American education. The question of what good education is was surprisingly absent from the book used in the seminar: Handbook of Education Policy Research (Sykes, Barbara, & Plank, 2009). The majority of the authors of this book were more interested in how we could make the educational system more efficient. More to the point, they were interested in how efficiency can be measured. This is why the main methodology used by the researchers was quantitative. Indeed, the assumption is that only quantitative methods allow for a more accurate judgment of reality at large, in this case the educational system, and show possible links between causes and effects.
‘Valeurs, normes et évaluations’.
Yves Michaud
EspacesTemps.net , 2005,
Abstract: Les normes se sont multipliées dans la réalité des pratiques et dans les modes de représentation des activités. Ce qui est relativement nouveau par rapport à une époque pas si lointaine où l’activité humaine était pensée en référence à des valeurs à la fois objectives et voulues par les sujets. Quelle est la signification du caractère conventionnel, utilitaire et collectif des normes ? Quelles sont les conséquences au plan de l’évaluation ? La pratique de l’évaluation systématique témoigne d’un mode de fonctionnement social qui fait intervenir flexibilité et réflexivité. On passe ainsi de l’ontologie des activités à leur être purement procédural. Norms invade our life in terms of normalized activities but also in terms of representation. This is something new compared to a not so distant time when human activities were described in reference to values which were both objective and the result of human will. What is the meaning of the conventional, utilitarian and collective nature of norms ? What are the consequences of this nature for evaluation ? The systematic benchmarking of activities and processes is connected to the presence of flexibility and reflexivity at the heart of the social system. We must realize that we moved from an ontology of action to a procedural view of it.
Science fiction as a culture of global innovation
Essachess : Journal for Communication Studies , 2010,
Abstract: Science fiction participates to the creation of a global culture of innovation. It is diffused in most of the developed countries to promote technical innovation and has motivated a lot of actors of capitalism to imitate the utopian technologies represented in these very popular movies and novels. The stake of this article is to define the strategic habitus in a cultural environment constituted of multiple centers of Research and Development (R&D) organized in network. The management of science fiction is necessary to optimize innovation at a global level. After the step of the ideological filtering of science fiction, the construction of discursive philters permits to manage productive systems with common and normalized cultural considerations. The approaches of sensemaking, storytelling and “strategy as discourse” are used at the theoretical level.
The National Longitudinal Survey of Children and Youth - Overview and Changes After Three Cycles
Michaud, Sylvie
Canadian Studies in Population , 2001,
Abstract: English The National Longitudinal Survey of Children and Youth (NLSCY) is a long-termstudy to monitor child development and well being of Canada's children as they grow from infancy toadulthood. To do so, a representative sample of Canadian children between 0-11 years old was selectedand interviewed in 1994-95. Interviews are conducted every two years and the current plans are tofollow that cohort of children until they reach the age of 25. The survey has now gone through threecollection cycles and already a number of changes hav been observed. The paper will give an overviewof the objectives of the survey, the survey design, the collection methodology, the survey content andthe products and research that have already been done. The last section will present the futuredirection of the survey. French L’Enquête nationale longitudinale sur les enfants et les jeunes concerne ledéveloppement et le bien-être des jeunes de l’enfance à la vie adulte. Unéchantillon représentatif d’enfants des ages 0-11 ans a d’abord fait parti del’enquête en 1994-1995. On veut continuer avec un interview chaque deux ansjusqu’à ce que les enfants ont 25 ans. Sur les trois premiers cycles, il y a déjàplusieurs changements. On décrit ici les objectifs de l’enquête, son dessin, laméthodologie de collecte, le contenu, la recherche qui à déjà été faite, et lefuture de l’enquête.
Vascular Tortuosities of the Upper Eyelid: A New Clinical Finding in Fabry Patient Screening
Langis Michaud
Journal of Ophthalmology , 2013, DOI: 10.1155/2013/207573
Abstract: Purpose. To report a new clinical finding related to Fabry disease. Methods. Fabry subjects were enrolled in the study, matched for age and sex with healthy individuals as a control group. This is a prospective review of all upper lid pictures taken for every subject at their last visit. A 4-step grading scale is proposed to classify this new entity. Results. Group A (Fabry) comprised 16 males and 22 females, aged 40 (±14) years on average. Group B (control) comprised 7 males and 8 females, aged 37 (±12) Vessels tortuosity was identified on the external superior lid in 36 of the Fabry patients (94.7%), while none of the subjects in group B showed similar vessels tortuosity. In addition, microaneurysms (MAs) were found in 10/38 group A subjects while none in group B presented a similar finding. The differences are highly significant. Conclusion. This paper proposes that blood vessels tortuosity on the upper eyelid be recognized as a new clinical entity for inclusion among the classic ocular manifestations of Fabry’s disease. Without evidence of any negative impact, it should be considered a benign sign contributing to evidence of suspected Fabry disease. 1. Introduction With an incidence varying from 1/3,000 newborn males to 1?:?40,000 or 1?:?117,000 live male births [1], Fabry is considered one of 7,000 known rare diseases that exist in the USA and elsewhere [2]. However, the number of patients is probably underestimated [3], because their symptoms are quite variable and unspecific, often leading to confusion with rheumatoid diseases or chronic inflammatory conditions [4]. A confirmatory diagnosis comes, on average, 14 years after the onset of the first symptoms for male adults and 16 years for females [5], three years for symptomatic children [6]. Considering the life-threatening aspect of the disease, this delay is unfortunate. Because ocular manifestations are among the first to appear in Fabry subjects [7], eye care practitioners are key players in detecting and screening for this disease. This paper aims to present a new clinical finding that may help them improve screening effort and alert them to potential Fabry subjects while performing slit lamp examinations. It also underscores the importance of examining the external surface of the upper lid, an area usually hidden and left unexplored during routine anterior segment examination of the eye. 2. Subjects and Methods The Université de Montréal, école d’Optométrie, is conducting a longitudinal study on ocular manifestations related to Fabry disease. Details of the study design and methods have
Impact of Anti-Inflammatory Agents on the Gene Expression Profile of Stimulated Human Neutrophils: Unraveling Endogenous Resolution Pathways
Mireille St-Onge, Aline Dumas, Annick Michaud, Cynthia Laflamme, Andrée-Anne Dussault, Marc Pouliot
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0004902
Abstract: Adenosine, prostaglandin E2, or increased intracellular cyclic AMP concentration each elicit potent anti-inflammatory events in human neutrophils by inhibiting functions such as phagocytosis, superoxide production, adhesion and cytokine release. However, the endogenous molecular pathways mediating these actions are poorly understood. In the present study, we examined their impact on the gene expression profile of stimulated neutrophils. Purified blood neutrophils from healthy donors were stimulated with a cocktail of inflammatory agonists in the presence of at least one of the following anti-inflammatory agents: adenosine A2A receptor agonist CGS 21680, prostaglandin E2, cyclic-AMP-elevating compounds forskolin and RO 20-1724. Total RNA was analyzed using gene chips and real-time PCR. Genes encoding transcription factors, enzymes and regulatory proteins, as well as secreted cytokines/chemokines showed differential expression. We identified 15 genes for which the anti-inflammatory agents altered mRNA levels. The agents affected the expression profile in remarkably similar fashion, suggesting a central mechanism limiting cell activation. We have identified a set of genes that may be part of important resolution pathways that interfere with cell activation. Identification of these pathways will improve understanding of the capacity of tissues to terminate inflammatory responses and contribute to the development of therapeutic strategies based on endogenous resolution.
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