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Search Results: 1 - 10 of 218056 matches for " Ana del Carmen; Denis de Armas "
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Comportamiento de la densidad mineral ósea en mujeres con artritis reumatoidea
Argüelles Zayas,Ana del Carmen; Infante Amorós,Adalberto; Flores Sánchez,Rosa María; de Armas,Reinaldo Denis;
Revista Cubana de Medicina , 2004,
Abstract: 40 premenopausic female patients under 45 with established diagnosis of rheumatoid athritis according to the criteria of the american college of rheumatology were studied. they were all under treatment with steroids with an equipment of osteal densitometry by ultrasound of the calcaneus. on analyzing the t-score average (as osteoporosis marker), we found that the lowest value was - 4.5 and the maximum -1.5. the t-student statistical test was used to compare the t-score average according to: dose, time of treament with steroids and time of evolution of the disease. osteoporosis was detected in 23 patients that received more than 20 mg of steroids, in 27 with more than 5 years of treatment with steroids, and in 23 with more than 5 years of evolution of the disease. on exploring the antecedent of fracture and relate it to the time of treatment and to the dose of steroids we observed that 9 patients (81-8 %) with more than 5 years of treatment and 6 (54.5 %) with more than 20 mg of steroids had had fractures.
Osteoporosis en mujeres premenopáusicas con bocio tóxico difuso
Infante Amorós,Adalberto; Argüelles Zayas,Ana del Carmen; Denis de Armas,Reinaldo; Gutiérrez,ángela;
Revista Cubana de Medicina , 2006,
Abstract: 2 women in premenopausal stage diagnosed as diffuse toxic goiter and a control group including 54 healthy women were studied. it was observed that the mean age in group 1 was 35.7 years old, and that in group 2 was 35,29 years old. the mean age for the 106 patients was 35.29. bone mineral density was measured using a bone densitometer by ultrasound (us) of the calcaneus (sonot 2000 medison). it was evident that the number of cases without bone alteration was greater in the control group: 40 cases (74.0 %) versus 8 (15.4 %) of group 1. this group had the greatest percentage of cases with osteopenia (22 [42.3 %]), and osteoporosis (22 [42.3 %]). on using non-parametric studies, such as the range test with wilcoxon's signs, it was found that there is a significant difference between the initial and the final test, according to the results obtained with osteosonometry. osteosonometry was normal a year after treatment in 19 patients over the initial test. osteoporosis disappeared in 10 patients. it was observed that the 16 patients with hyperthyroidism on conducting the final study of osteosonometry, had osteopenia or steoporosis, whereas in the 25 euthyroid patients osteosonometry was normal. finally, 27 subjects had osteosonometry results within the normal range and 19 above the first study. among the subjects that were applied the treatment scheme 3, osteosonometry was normal in 15 of them. it was also the group with less osteoporotic patients (only 2), although in treatment 2, the response was fairly adequate, which was not so in treatment 1
Comportamiento de la densidad mineral ósea en mujeres con artritis reumatoidea Behavior of the osteal mineral density in women with rheumatoid arthritis
Ana del Carmen Argüelles Zayas,Adalberto Infante Amorós,Rosa María Flores Sánchez,Reinaldo Denis de Armas
Revista Cubana de Medicina , 2004,
Abstract: Se estudiaron 40 pacientes del sexo femenino, premenopáusicas, menores de 45 a os, con diagnóstico establecido de artritis reumatoidea según criterios del Colegio Americano de Reumatología y todas con tratamiento de esteroides, con un equipo de densitometría ósea por ultrasonido del calcáneo. Al analizar el promedio de t-score (como marcador de osteoporosis), encontramos que el valor más bajo de fue de - 4,5 y el máximo de -1,5. Se empleó el test estadístico t -Student para comparar los promedio del t-score según: dosis, tiempo de tratamiento con esteroides y tiempo de evolución de la enfermedad. Se encontró osteoporosis en 23 pacientes que tomaban más de 20 mg de esteroides; en 27 con más de 5 a os de tratamiento con esteroides; y en 23 con más de 5 a os de evolución de la enfermedad. Al explorar el antecedente de fractura y relacionarlo con el tiempo de tratamiento y la dosis de esteroides encontramos que 9 pacientes (81,8 %) con más de 5 a os de tratamiento y 6 (54,5 %) con más de 20 mg de esteroides tienen antecedente de fractura. 40 premenopausic female patients under 45 with established diagnosis of rheumatoid athritis according to the criteria of the American College of Rheumatology were studied. They were all under treatment with steroids with an equipment of osteal densitometry by ultrasound of the calcaneus. On analyzing the t-score average (as osteoporosis marker), we found that the lowest value was - 4.5 and the maximum -1.5. The t-Student statistical test was used to compare the t-score average according to: dose, time of treament with steroids and time of evolution of the disease. Osteoporosis was detected in 23 patients that received more than 20 mg of steroids, in 27 with more than 5 years of treatment with steroids, and in 23 with more than 5 years of evolution of the disease. On exploring the antecedent of fracture and relate it to the time of treatment and to the dose of steroids we observed that 9 patients (81-8 %) with more than 5 years of treatment and 6 (54.5 %) with more than 20 mg of steroids had had fractures.
Osteoporosis en mujeres premenopáusicas con bocio tóxico difuso Osteoporosis in premenopausal women with toxic diffuse goiter
Adalberto Infante Amorós,Ana del Carmen Argüelles Zayas,Reinaldo Denis de Armas,ángela Gutiérrez
Revista Cubana de Medicina , 2006,
Abstract: Se estudió un grupo de 52 mujeres en etapa premenopáusica con diagnóstico de bocio tóxico difuso y un grupo control constituido por 54 mujeres sanas. Se encontró que la media para la edad en el grupo 1 fue de 35,7 a os y para el grupo 2, de 34,83 y la media en las 106 pacientes fue de 35,29 a os. Se midió la densidad mineral ósea mediante un equipo de densitometría ósea por ultrasonido del calcáneo (SONOST 2000 Medison). Se evidenció que el número de casos sin alteración ósea fue mayor en el grupo control: 40 casos (74,0 %), contra 8 (15,4 %) del grupo 1, y este grupo tuvo el mayor porcentaje de casos con osteopenia (22 [42,3 %]) y osteoporosis (22 [42,3 %]). Al utilizar estudios no paramétricos como el test de Rangos con signos de Wilcoxon encontramos que existe diferencia significativa entre el estudio inicial y el final, según los resultados de la osteosonometría. La osteosonometría fue normal al a o del tratamiento en 19 pacientes por encima de la realizada inicialmente, y la osteoporosis desapareció en 10 pacientes. Se halló que los 16 que se mantuvieron hipertiroideos al realizarle el estudio final de osteosonometría, presentaban osteopenia u osteoporosis. Mientras que en los 25 pacientes eutiroideos la osteosonometría fue normal. Al final, 27 sujetos tuvieron un resultado en la osteosonometría en el rango normal, 19 por encima del estudio inicial. En los sujetos a los que se les aplicó el esquema de tratamiento 3, en 15 la osteosonometría fue normal, así como que fue el grupo que menos pacientes osteoporóticos tuvo, con 2 solamente, aunque con el tratamiento 2 la respuesta fue bastante adecuada, no así con el tratamiento 1 2 women in premenopausal stage diagnosed as diffuse toxic goiter and a control group including 54 healthy women were studied. It was observed that the mean age in group 1 was 35.7 years old, and that in group 2 was 35,29 years old. The mean age for the 106 patients was 35.29. Bone mineral density was measured using a bone densitometer by ultrasound (US) of the calcaneus (SONOT 2000 Medison). It was evident that the number of cases without bone alteration was greater in the control group: 40 cases (74.0 %) versus 8 (15.4 %) of group 1. This group had the greatest percentage of cases with osteopenia (22 [42.3 %]), and osteoporosis (22 [42.3 %]). On using non-parametric studies, such as the range test with Wilcoxon's signs, it was found that there is a significant difference between the initial and the final test, according to the results obtained with osteosonometry. Osteosonometry was normal a year after treatment in 19 patients
Síndrome metabólico en familiares de primer grado de pacientes con diabetes mellitus tipo 2
Calderín Bouza,Raúl Orlando; Yánez Quesada,Miguel Angel; Márquez Pérez,Ileana; Senra Piedra,Gerardo; Denis de Armas,Reinaldo; Infante Amorós,Adalberto; Argüelles Zayas,Ana del Carmen; Orlando González,Neraldo; Yánez Quesada,Marelis; Albert Cabrera,Marcos;
Revista Cubana de Endocrinolog?-a , 2005,
Abstract: a cross-sectional descriptive study of 340 persons assigned to two groups, with and without family history of diabetes mellitus type 2 (dm2), was carried out. the objective was to detect whether those persons with family history of dm2 had more hyperinsulemia, metabolic syndrome, associated cardiovascular risk factors and target organ lesions, expressed in left ventricle hypertrophy, than subjects without diabetes family history. the result was that hyperinsulemia was present in 96 patients with family history of dm2 (56,5 %) and significance level of p= 0,001. metabolic syndrome was more frequent in subjects with family history of dm2 (90) for 52,9 % of cases and p= 0,000. hypertriglyceridemia was both the most noticeable marker of the metabolic syndrome and the most statistically significant risk factor in subjects with family history of dm2 (96 , 52,9 % of cases and p= 0,000). left ventricle hypertrophy was associated as target organ lesion expression to subjects with family history of dm2 (36: 21,2 % and p=0,043). it was concluded that subjects with family history of dm2 are more likely to have hyperinsulinemia, metabolic syndrome, cardiovascular risk factors and target organ lesions than those persons without such a family history of dm2.
Perfil situacional y estrategias de intervención en la región mesoamericana en el área de salud materna, reproductiva y neonatal
Hernández-Prado,Bernardo; Kestler,Edgar; Díaz,Juan; Walker,Dilys; Langer,Ana; Lewis,Sarah; Vara-Salazar,Elvia De la; Melo-Zurita,María del Carmen; Iriarte,Emma; Danel,Isabella; Donnay,France; Alemán,Denis; Serrano,Roselyn; Morales,Evelyn; Largaespada,Natalia; González,José Douglas Jarquín; Hernández,Ma del Carmen; Mejía,Claudia E Quiroz; González,Geneva; Carrera,Yadira; Valverde,Clelia; Luna,Rufino; Valencia-Mendoza,Atanacio; Sosa-Rubí,Sandra G; Hernández-Prado,Bernardo; Kestler,Edgar; Díaz,Juan; Walker,Dilys; Langer,Ana; Lewis,Sarah; Vara-Salazar,Elvia De la; Melo-Zurita,María del Carmen; ,;
Salud Pública de México , 2011, DOI: 10.1590/S0036-36342011000900005
Abstract: to present the main results of the regional situation diagnosis and intervention plan developed in 2010 as part of the planning activities of the mesoamerican health system by the working group on maternal, reproductive and neonatal health. a group of experts and representatives from countries in the region (central america and nine southern mexican states) conducted an exhaustive review of available data to construct a situational analysis and a review of effective practices for improving maternal, reproductive and neonatal health. finally, the group proposed a regional action plan, defining regional goals and specific interventions. the situational diagnosis suggests that, although there has been progress in the last 10 years, maternal and neonatal mortality rates are still unnaceptably high in the region, with a substantial variability across countries. the group proposed as a regional goal the reduction of maternal and neonatal mortality in accordance with the millenium development goals. the regional plan recommends specific maternal and neonatal health interventions emphasizing obstetric and neonatal emergency care, skilled birth attendance and family planning. the plan also includes a five year implementation strategy, along with training and evaluation strategies. the regional plan for maternal, neonatal and reproductive health has the potential to be successful, provided it is effectively implemented.
Seguimiento seroepidemiológico de contactos sexuales de individuos seropositivos al HTLV-I en Cuba
Díaz Torres,Héctor M.; Nibot Sánchez,Carmen; Cruz Sui,Otto; Blanco de Armas,Madelín; Sánchez Ruiz,Julieta; Lubián Caballero,Ana Luisa;
Revista Cubana de Medicina Tropical , 2009,
Abstract: introduction: the human t cell lymphotropic virus type i (htlv-i) is considered to be endemic in the caribbean area, with rates of seroprevalence from 3 to 6 %. its routes of transmission are sexual, vertical and parenteral. it also circulates in cuba, though seroprevalence is much lower. heterosexual transmission is a frequently reported way of contagion. objectives: to determine htlv-i seroprevalence in the sexual partners of htlv-i infected individuals and also to assess important epidemiological factors that could have an impact on the transmission. methods: a prospective sero epidemiological follow-up study was conducted with the sexual partners of the htlv-i infected individuals who were identified by the national program of std/hiv/aids. after counseling sessions and well-informed consent, an epidemiological survey was designed using data from the sexual partners and their serological follow up. diagnosis was based on the elisa and western blot davih htlv-i and davih blot htlv-i systems, and the statistical processing used epidat program. results: seropositivity of the sexual partners was significantly higher in men than in women (53.3% vs. 9.09%, p< 0.05). the average time of exposure of the positive and negative partners of men and women did not show significant difference. conclusion: the results revealed greater efficiency in the transmission of htlv-i from men to women and also evinced its presence in cuba as sexually-transmitted disease. the authors believe that this information should be used during the counseling service.
Guía para la elaboración del análisis de la situación de salud en la atención primaria Guide for the analysis of the health situation in primary health care
María del Carmen Pría Barros,Isabel Louro Bernal,Ana Teresa Fari?as Reinoso,Héctor Gómez de Haz
Revista Cubana de Medicina General Integral , 2006,
Abstract: El análisis de la situación de salud es una práctica necesaria en la Atención Primaria de Salud, cuyo propósito es la identificación y el grado de prioridad de los problemas de salud de la comunidad para desarrollar acciones que contribuyan a su solución. El objetivo de este trabajo es presentar una guía para realizar ese análisis en la comunidad. Para su dise o se realizó una revisión de las guías existentes, se consultó a expertos sobre el tema, y sobre esta base se elaboró una guía de evaluación de los informes del análisis de la situación de salud de los consultorios médicos en Cuba. A partir de los resultados obtenidos en la evaluación realizada, se propone la presente guía para la elaboración de este análisis en la comunidad. Esta contribuye a organizar el proceso de búsqueda de información, a orientar el análisis, la síntesis y a la creación, toda vez que se espera que el equipo de salud elabore, indague, profundice, integre y cree una propuesta de transformación de la situación de salud de su comunidad
ENFOQUE GLOBAL DE LA FARMACOTERAPIA
Blanca de la Nogal Fernández,Carmen Martinez-Díaz,Virginia del Río Polo,Ana Gil Martín
Electronic Journal of Biomedicine , 2006,
Abstract: RESUMEN: Los pacientes ancianos (mayores de 65 a os) representan en Espa a el 18% de la población, y son responsables del 70% del gasto farmacéutico. Las previsiones son que para el a o 2020, esta cifra se haya incrementado considerablemente. Una característica inequívoca del paciente anciano es la pluripatología, que condiciona la utilización de varios medicamentos por persona y día. El número total de fármacos es el principal factor asociado a la aparición de efectos adversos, interacciones, errores de medicación e incumplimiento. Por otra parte, no todos los fármacos prescritos tienen una utilidad terapéutica demostrada, están indicados o son apropiados para estos pacientes.El objetivo de esta revisión es identificar las causas, analizar las posibles consecuencias y proponer recomendaciones para que se haga un uso más racional de los medicamentos. Es imprescindible la participación de un equipo multidisciplinar constituido por: médicos de especializada y de primaria, enfermeros, farmacéuticos, auxiliares, familiares de los pacientes y el propio paciente siempre que sea posible. Hay que hacer hincapié de una manera especial en los pacientes que se encuentran institucionalizados. ABSTRACT: GLOBAL THERAPEUTIC PERSPECTIVE IN GERIATRIC PATIENTS.Elder people (> 65 years old) are 18% of population in Spain, and are responsible for 70% of pharmaceutical cost. In 2020, this fact will be increase substantially. Pluripathologies and many drugs prescribed are two characteristics of elderly patients. The number of drugs/patient is the principal factor associate with adverse reactions, interactions, drug′s mistakes and non-completion. Some drugs of the treatment′s patient could be inappropriate, no prescribed or low utility.In this review, we indicate the causes and consequences of the geriatrics pharmacotherapy. We show recommendations for a better use of drugs in the elderly.It′s essential that we work with a variety of disciplines: doctors, nurses, pharmacists, family and the patient. It′s important to attend the people who live in geriatric centers.
On the Performance of Trimetazidine and Vitamin E as Pharmacoprotection Agents in Cyclosporin A-Induced Toxicity
De la Cruz Rodríguez Lilia Cristina,Rey María del Rosario,Araujo Carmen Rosa,Oldano Ana Veronica
ISRN Pharmacology , 2013, DOI: 10.1155/2013/605640
Abstract: The immunosuppressant drug cyclosporin A (CyA) has been used in diseases with immunological basis and in transplant patients. Nephrotoxicity and hepatotoxicity are the main adverse effects of this drug. To find a protective drug against those effects we assayed the cardioprotector Trimetazidine (TMZ) and vitamin E, used as nutritional supplements to alleviate oxidative stress. Six groups of eight male Wistar rats each were prepared (groups A–F): A, control; B, vitamin E (10?mg/Kg/day); C, TMZ (20?mg/Kg/day); D, 25?mg/Kg/day CyA; E, CyA and vitamin E (25?mg/Kg/day CyA + 10?mg/Kg/day Vit E); F, TMZ for 20 days (20?mg/kg/day); and then CyA (25?mg/kg/day) and TMZ (20?mg/Kg/day). The experiment lasted 120 days. The exposure of rats to CyA promoted nephrotoxicity and hepatotoxicity with an increase in serum urea, creatinine, and glutamate dehydrogenase (GLDH). Structural and ultrastructural studies of liver and kidney were performed. Group D showed adverse effects induced by CyA since statistically significant differences were found with respect to the control group (A). Vitamin E (E) showed no protective effect. Pretreatment with TMZ (F) attenuated the adverse effects of CyA. We conclude that CyA-induced nephrotoxicity and hepatotoxicity are attenuated by the cytoprotective effect of TMZ. TMZ inhibits the reabsorption and, consequently, the accumulation of CyA in the cell. The antioxidant capacity of vitamin E did not improve the effect of CyA. 1. Introduction Cyclosporin A (CyA) is a cyclic undecapeptide with strong immunosuppressive activity, since it has a specific inhibitory effect on the T-cell receptor signal transduction pathway [1, 2]. Reactive oxygen species (ROS) have been implicated in the nephrotoxicity and hepatotoxicity caused by CyA, either by direct action or by the activation of lipid peroxidation (LP) [3–6]. Our previous work showed that the effect of CyA on the antioxidant defense system (ADS) is related to lipoperoxidation and liver function. The results for the chronic and acute treatment, only with 20?mg/Kg/day of CyA, caused alterations in liver parenchyma histoarchitecture [7]. In previous works we showed that CyA administration to organ transplant patients caused an increase in the levels of serum creatinine and urinary excretion of gamma-glutamyl transpeptidase (uGGT). These functional changes were dose and time dependent, showing structural alterations with doses higher than 15?mg/Kg/day CyA in chronic treatments [8]. Morphofunctional alterations in the liver parenchyma were observed in rats treated with CyA at different doses for
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