oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

4 ( 1 )

2019 ( 46 )

2018 ( 258 )

2017 ( 282 )

Custom range...

Search Results: 1 - 10 of 243340 matches for " Ana Vanesa; Pérez Valencia "
All listed articles are free for downloading (OA Articles)
Page 1 /243340
Display every page Item
Influencia en la dosis de diálisis de diferentes flujos de líquido dializante en el paciente tratado con hemodiafiltración on-line o hemodiálisis convencional Influence on the dialysis doses of different flow rates of dialysis fluid in patients treated with online haemodiafiltration or conventional haemodialysis
Ana Vanesa Fernández Martínez,Laura Pérez Valencia,Javier Fernández Caro Sánchez,María Ruiz Serna
Revista de la Sociedad Espa?ola de Enfermería Nefrológica , 2011,
Abstract: La dosis de diálisis influye sobre la supervivencia del paciente en hemodiálisis, además de influir en la corrección de la anemia, en el estado nutricional y en el control de la tensión arterial, entre otros. Algunos autores han se alado el flujo del líquido dializante como un factor determinante de la dosis de diálisis del paciente en hemodiálisis de alto flujo y hemodiafiltración. El objetivo del presente estudio es evaluar el impacto en la eficacia de la diálisis de diferentes flujos de líquido dializante en pacientes tratados con hemodiafiltración on-line postdilucional y hemodiálisis convencional, mediante la medición del volumen convectivo final y del aclaramiento de peque as moléculas mediante el Kt. En todos los pacientes se realizan 9 sesiones de diálisis consecutivas variando el Qd: 3 sesiones con Qd 500 ml/min, 3 sesiones con Qd 800 ml/min y 3 sesiones con autoflujo . De los resultados obtenidos, el Kt se muestra significativamente mayor con Qd 800 ml/min (59,69 ± 6,07 litros) con respecto a Qd 500 ml/min (56,51 ± 6,33 litros, p<0,001) y autoflujo (58,02 ± 4,89 litros); así como el Kt del autoflujo mayor (p<0,001) que Qd 500 ml/min. El aumento del flujo de líquido dializante conlleva un incremento en la dosis de diálisis en pacientes tratados con hemodiafiltración on-line. El autoflujo consigue un incremento de dosis apreciable con respecto al Qd de 500 ml/min con un mínimo coste adicional, por lo que debería de considerarse como una medida en un esquema global de tratamiento, que permita la individualización en cada paciente. The dialysis dose affects survival of patients undergoing dialysis, as well as affecting the correction of anaemia, the nutritional state and the control of blood pressure, among others. Some authors have indicated the dialysis fluid flow rate as a determining factor in the dialysis dose for patients undergoing high-flow haemodialysis and haemodiafiltration. The aim of this study is to evaluate the impact on the dialysis efficacy of different flow rates of dialysis fluid in patients treated with on-line post-dilution haemodiafiltration and conventional haemodialysis, by measuring the final convective volume and rinse solution volume of small molecules using Kt. In all patients, 9 consecutive dialysis sessions were carried out varying the Qd: 3 sessions with Qd 500 ml/min, 3 sessions with Qd 800 ml/min and 2 sessions with autoflow. From the results obtained, Kt is shown to be significantly higher with Qd 800 ml/min (59.69 ± 6.07 litres) compared to Qd 500 ml/min (56.51 ± 6.33 litres, p<0.001) and autoflow (58.02 ± 4.89 l
Influencia en la dosis de diálisis de diferentes flujos de líquido dializante en el paciente tratado con hemodiafiltración on-line o hemodiálisis convencional
Fernández Martínez,Ana Vanesa; Pérez Valencia,Laura; Fernández Caro Sánchez,Javier; Ruiz Serna,María; Horrillo Jiménez,Francisco; Caparros Ríos,Virginia; García Navarro,Francisca; Vilar Torres,Ma Victoria;
Revista de la Sociedad Espa?ola de Enfermería Nefrológica , 2011, DOI: 10.4321/S1139-13752011000100006
Abstract: the dialysis dose affects survival of patients undergoing dialysis, as well as affecting the correction of anaemia, the nutritional state and the control of blood pressure, among others. some authors have indicated the dialysis fluid flow rate as a determining factor in the dialysis dose for patients undergoing high-flow haemodialysis and haemodiafiltration. the aim of this study is to evaluate the impact on the dialysis efficacy of different flow rates of dialysis fluid in patients treated with on-line post-dilution haemodiafiltration and conventional haemodialysis, by measuring the final convective volume and rinse solution volume of small molecules using kt. in all patients, 9 consecutive dialysis sessions were carried out varying the qd: 3 sessions with qd 500 ml/min, 3 sessions with qd 800 ml/min and 2 sessions with autoflow. from the results obtained, kt is shown to be significantly higher with qd 800 ml/min (59.69 ± 6.07 litres) compared to qd 500 ml/min (56.51 ± 6.33 litres, p<0.001) and autoflow (58.02 ± 4.89 litres); and kt in autoflow was found to be higher (p<0.001) than qd 500 ml/min. the increase in flow rate of dialysis fluid means an increase in the dialysis dose in patients treated with online haemodiafiltration. the autoflow achieves an appreciable increase in dose compared to qd of 500 ml/min with a minimum additional cost, and should therefore be considered as a measure in an overall treatment framework, permitting individualization of treatment for each patient.
Reassessing the role of mitochondrial DNA mutations in autism spectrum disorder
Vanesa álvarez-Iglesias, Ana Mosquera-Miguel, Ivón Cuscó, ángel Carracedo, Luis Pérez-Jurado, Antonio Salas
BMC Medical Genetics , 2011, DOI: 10.1186/1471-2350-12-50
Abstract: We analysed a cohort of 148 patients with idiopathic ASD for a number of mutations proposed in the literature as pathogenic in ASD. We also carried out a case control association study for the most common European haplogroups (hgs) and their diagnostic single nucleotide polymorphisms (SNPs) by comparing cases with 753 healthy and ethnically matched controls.We did not find statistical support for an association between mtDNA mutations or polymorphisms and ASD.Our results are compatible with the idea that mtDNA mutations are not a relevant cause of ASD and the frequent observation of concomitant mitochondrial dysfunction and ASD could be due to nuclear factors influencing mitochondrion functions or to a more complex interplay between the nucleus and the mitochondrion/mtDNA.Autism/autistic spectrum disorders (ASD) are complex neurodevelopmental conditions affecting approximately one in 150 children. They are characterized by a disturbance in communication skills and reciprocal social interaction, along with restrictive and repetitive behaviours. There is increasing evidence that ASD have an important genetic component with aetiological heterogeneity, including association with several metabolic disorders [1,2]. Rare mutations in a few genes, copy number variants (CNVs) disrupting functional pathways and linkage or association to a number of different loci can account for the genetic aetiology or liability to ASD in up to 20% of cases [1,3-6].Recent studies have also suggested that impairment of mitochondrial energy metabolism plays a role in the aetiology of ASD [7-9]. The study by Oliveira et al. [2] found that 7% of children in a population-based survey of school-age children with ASD met the criteria for mitochondrial respiratory chain disorders, and that they were also clinically indistinguishable from other children with ASD. This already recognized feature of ASD has lead several researchers to analyse mutations of the mtDNA as potential risk factors in ASD. Thu
Infusión automatizada manual en la hemodiafiltración on-line postdilucional: hacia la optimización del volumen de reinfusión Manual automated infusion in post-dilution on-line haemodiafiltration: towards optimizing the reinfusion volume
Ana Vanessa Fernández Martínez,Francisco Horrillo Jiménez,Laura Pérez Valencia,Salvadora Soto Ure?a
Revista de la Sociedad Espa?ola de Enfermería Nefrológica , 2011,
Abstract: Las técnicas de hemodiafiltración (HDF) con altos volúmenes convectivos, constituyen una interesante forma de depuración por su aproximación a la del ri ón nativo. De entre ellas, la HDF on-line postdilucional es el modo de infusión más eficaz para la eliminación de moléculas de diferentes pesos moleculares. Recientes avances en la tecnología permiten la prescripción automática del flujo de infusión (Qi), resultando al menos tan eficaz como el manual. El objetivo del presente estudio es evaluar si es posible incrementar la eficacia de la infusión automatizada en la HDF on-line postdilucional, incrementando manualmente el Qi inicial, mediante la medición del volumen convectivo final y del Kt. Por otro lado, se evalúan las cargas de enfermería medidas por el número de intervenciones relacionadas con la técnica. En todos los pacientes (n 96) se realizan 3 sesiones de diálisis (ST 5008 Fresenius Medical Care) con reinfusión automática, y seguidamente, otras 3 sesiones con reinfusión automatizada manual incrementando el Qi en 10 ml/min al medido automaticamente. De los resultados obtenidos, se aprecian diferencias significativas (p<0,001) en el volumen de reinfusión, siendo un 6% mayor en la forma automatizada manual (23,01 ± 2,22 litros) que en la automatizada (21,7 ± 2,62 litros). El 75% de los pacientes alcanzan 20 litros o más con la autosustitución, frente al 87,5% con la sustitución automatizada manual (p<0,001). No existen diferencias en cuanto al Qb, Qd, tiempo efectivo de diálisis y Kt. El número de intervenciones por alarmas relacionadas con la técnica del personal de enfermería es superior (p=0,001). Haemodiafiltration (HDF) techniques with high convective volumes are an interesting form of filtering due to their approximation to the native kidney. Among them, post-dilution on-line HDF is the most efficacious form of infusion for eliminating molecules with different molecular weights. Recent advances in technology permit the automatic prescription of the infusion flow (Qi), proving at least as efficacious as manual infusion. The aim of this study is to assess whether it is possible to increase the efficacy of automated infusion in post-dilution on-line HDF by manually increasing the initial Qi by measuring the final convective volume and Kt. The nursing workloads are also assessed, measured by the number of interventions related to the technique. In all patients (n 96) 3 dialysis sessions are carried out (ST 5008 Fresenius Medical Care) with automatic reinfusion, followed by another 3 sessions with manual automated reinfusion increasing the Qi by
La diferencia entre tiempo programado y efectivo en hemodiafiltración en línea: Cada minuto cuenta en la eficacia dialítica? The difference between programmed time and effective time in online haemodiafiltration: Does every minute count in dialytic efficiency?
Ana Vanessa Fernández Martínez,Rocío Pérez Díaz,Laura Pérez Valencia,Virginia Caparrós Ríos
Enfermería Nefrológica , 2012,
Abstract: Introducción: El factor tiempo es determinante en la eficacia de la diálisis, recomendando las European Best Practices Guides of Dialysys Adequaccy una duración semanal no inferior a 720 minutos. Los modernos monitores de diálisis interrumpen el procedimiento por auto chequeos que incrementan la seguridad. Esos minutos de diferencia no han sido tenidos en cuenta en otros resultados obtenidos, algún autor ya hace referencia a la necesidad de contemplarlos. Los objetivos del presente estudio fueron determinar la diferencia real entre el tiempo programado y el tiempo efectivo de diálisis, y una vez comprobado incrementar la duración de la sesión para hacer que el tiempo efectivo sea realmente el deseado en cada paciente, y nunca inferior a 240 minutos por sesión. Finalmente comprobamos si existen diferencias en la eficacia dialítica, midiendo el Kt y el volumen total de reinfusión. Pacientes y métodos: Dise amos un estudio prospectivo sobre población prevalente en hemodiafiltración on-line. Reclutamos 152 pacientes en hemodiafiltración on-line. Durante 6 sesiones consecutivas (912 sesiones) la diálisis se efectuó con un tiempo programado ≥ 240 minutos. En un segundo periodo 6 sesiones consecutivas (912 sesiones), la sesión de diálisis se alargó hasta un tiempo efectivo igual al previo programado. La variable principal en estudio fue el tiempo, siendo variables secundarias el flujo sanguíneo, Kt, y volumen total de reinfusión. En el segundo periodo se recogieron posibles complicaciones intradialíticas en el tiempo a adido. Resultados: Se analizan 152 pacientes, 66% hombres, de 65,7 ± 14,9 (26-88) a os de edad, con una permanencia en diálisis de 56,5 ± 59,5 meses, en un total de 1824 sesiones de hemodiafiltración on-line. No se aprecian diferencias significativas en Qb (428,74±39,73 vs 429,86±38,54 ml/min). El tiempo medio de la sesión aumenta significativamente (p<0,001) en 7 minutos (de 233,58±3,29 hasta 240,67±2,71 minutos). El Kt aumenta significativamente (p<0,001) un 3,2% (desde 60,06±5,86 hasta 61,99±5,80 litros), disminuyendo el % de sesiones en las que no se alcanza el Kt deseado por superficie corporal (de 5,7% a 3,1%). El volumen total de reinfusión se incrementa significativamente (p<0,001) un 1,5% (de 24,10±2,72 a 24,46±2,77 litros), con un % similar de sesiones donde no se alcanzan los 20 litros objetivo (4,6% versus 4,3%). No se observan complicaciones intradialíticas en el periodo de tiempo incrementado ni episodios de coagulación. Discusión y conclusiones: Tanto Kt como volumen total de reinfusión son los principales indicadores reconocidos p
Diferencia entre tiempo programado y tiempo efectivo en hemodiafiltración on-line: Cada minuto cuenta en la eficacia dialítica?
Ana Vanessa Fernández Martínez,Rocío Pérez Díaz,Laura Pérez Valencia,Virginia Caparrós Ríos
Enfermería Nefrológica , 2012,
Abstract:
Evaluación toxicológica aguda de los extractos fluidos al 30 y 80 % de cymbopogon citratus (D.C.) stapf (ca?a santa)
Martínez Guerra,María Julia; Betancour Badell,José; Ramírez Albajes,Ana Rosa; Barceló Pérez,Héctor; Meneses Valencia,Rafael; Lainez Azcuy,Arnaldo;
Revista Cubana de Plantas Medicinales , 2000,
Abstract: the acute toxicologic evaluation of the fluid extracts 30 and 80 % of cymbopogon citratus (d.c.) stapf (lemon grass), a plant used for its anticatarrhal, antiasthmatic, diuretic and antitussive effect and to control the arterial pressure was made. it was shown that the manifestations of toxicity are more evident as the concentration of fluid is higher. these manifestations were more probable among the animals treated with fluid extract 80 %. it was observed that the damages centered in the stomach with mild vascular congestion and focal hemorrhagic infiltrate in the lamina propia, liver and kidney, where the histological findings allow to confirm the hepatotoxic and nephrotoxic effect of these fluid extracts.
Comparación de infusión automática respecto a manual en hemodiafiltracion "on line" post - dilucional
Fernández Martínez,Ana Vanessa; Soto Ure?a,Salvadora; Arenas Fuentes,Maria; Horrillo Jiménez,Francisco; Sáez Donaire,Natalia; Pérez Valencia,Laura;
Revista de la Sociedad Espa?ola de Enfermería Nefrológica , 2010, DOI: 10.4321/S1139-13752010000100003
Abstract: post-dilutional online haemodiafiltration is the most efficacious infusion method for the elimination of molecules with different molecular weights; it has also been associated to a better control of anaemia and of the nutritional condition of the patient, presenting lower morbility for patients undergoing haemodialysis. recently, major advances have been made in the technology enabling the automatic prescription of the infusion flow, which could reduce the nursing workloads. the aim of this study is to evaluate the efficacy of automatic infusion compared to manual infusion in post-dilutional online hdf, by measuring the final convective volume and the rinsing volume of small molecules using kt. the nursing workloads were also evaluated, measured by the number of interventions related to the technique, an evaluation of the convenience and efficacy perceived by nursing staff and whether there were differences in the patient's comfort during the session. a prospective study was designed of 86 patients; after three sessions with each of the reinfusion modes, significant differences were observed both in the replacement volume (1.5 litres) and in the dialysis dose administered, measured using kt (1.02 litres), which are higher in the automatic form. furthermore, the subjective evaluation of nursing staff is much higher in the automatic mode compared to manual, both in perceived efficacy and in convenience. patients also expressed greater comfort in sessions with automatic reinfusion as the number of acoustic alarms was reduced, favouring rest. although the clinical effects were slight, automatic reinfusion is shown to be a good alternative especially in relation to the adaptation to the technique by nursing staff and by patients.
New Population and Phylogenetic Features of the Internal Variation within Mitochondrial DNA Macro-Haplogroup R0
Vanesa álvarez-Iglesias, Ana Mosquera-Miguel, Maria Cerezo, Beatriz Quintáns, Maria Teresa Zarrabeitia, Ivon Cuscó, Maria Victoria Lareu, óscar García, Luis Pérez-Jurado, ángel Carracedo, Antonio Salas
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0005112
Abstract: Background R0 embraces the most common mitochondrial DNA (mtDNA) lineage in West Eurasia, namely, haplogroup H (~40%). R0 sub-lineages are badly defined in the control region and therefore, the analysis of diagnostic coding region polymorphisms is needed in order to gain resolution in population and medical studies. Methodology/Principal Findings We sequenced the first hypervariable segment (HVS-I) of 518 individuals from different North Iberian regions. The mtDNAs belonging to R0 (~57%) were further genotyped for a set of 71 coding region SNPs characterizing major and minor branches of R0. We found that the North Iberian Peninsula shows moderate levels of population stratification; for instance, haplogroup V reaches the highest frequency in Cantabria (north-central Iberia), but lower in Galicia (northwest Iberia) and Catalonia (northeast Iberia). When compared to other European and Middle East populations, haplogroups H1, H3 and H5a show frequency peaks in the Franco-Cantabrian region, declining from West towards the East and South Europe. In addition, we have characterized, by way of complete genome sequencing, a new autochthonous clade of haplogroup H in the Basque country, named H2a5. Its coalescence age, 15.6±8 thousand years ago (kya), dates to the period immediately after the Last Glacial Maximum (LGM). Conclusions/Significance In contrast to other H lineages that experienced re-expansion outside the Franco-Cantabrian refuge after the LGM (e.g. H1 and H3), H2a5 most likely remained confined to this area till present days.
Comparación anatómica de Nitrophila australis var. australis y Nitrophila occidentalis (Chenopodiaceae): Su importancia taxonómica
Pérez Cuadra,Vanesa; Hermann,Paula M.;
Bolet?-n de la Sociedad Argentina de Bot??nica , 2009,
Abstract: its taxonomic importance. nitrophila australis is an endemic halophyte species of argentina while nitrophila occidentalis is a native halophyte of north america, both belonging to polycnemoideae (chenopodiaceae). they are similar in foliar anatomy: one-layered epidermis, homogeneous chlorenchyma, acqueous tissue and one large central bundle with a variable number of smaller ones on each side of the latter; the main difference stands in the cuticular striae and marginal ribs on each side of the leaf. the stem of both species shows a one-layered epidermis, subepidermic angular collenchyma and a cortical aerenchymatous parenchyma. four bundles occur in the stele of n. australis while in n. occidentalis there are eight; both show caps of collenchyma associated with each bundle. a superficial phellogen originates in the rhizome of the argentinean species, whereas in the american one it differenciates deep in the cortex. the number of bundles in the rhizome stele of both is variable. although the general morphological and anatomical characteristics are similar in the species studied, each one has certain specific features, rendering the anatomical study taxonomically valuable at the species level.
Page 1 /243340
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.