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Search Results: 1 - 10 of 7848 matches for " Amy Sau Ching Ha "
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Hong Kong Physical Education Teachers’ Beliefs about Teaching Students with Disabilities: A Qualitative Analysis
Jing Qi,Amy Sau Ching Ha
Asian Social Science , 2012, DOI: 10.5539/ass.v8n8p3
Abstract: This study aims to identify and examine the beliefs of physical education (PE) teachers in Hong Kong toward teaching students with disabilities. Based on the Theory of Planned Behavior (Ajzen, 1991), a qualitative design was employed to examine the underlying beliefs (behavioral, normative, and control) of PE teachers regarding teaching students with disabilities in their mainstream curricular PE. Participants were five Hong Kong PE teachers (F=3, M=2). Data were gathered in individual semi-structured interviews, analyzed and presented as descriptive summaries by content analysis (Patton, 2002). Results show that PE teachers intend to implement inclusive practices because of their motivation to comply with inclusive policies and significant referents (SN), and their perceived behavior control (PBC), although they have less than favorable attitudes toward inclusion and toward teaching students with disabilities (AB). These results confirm the importance of subjective norms and perceived behavior control on the decisions of teachers to teach students with disabilities in inclusive PE settings. This study brings to the literature information on the beliefs of PE teachers regarding inclusion and teaching students with disabilities.
The Teacher Development in Physical Education: A Review of the Literature
Carrie Li-Juan Wang,Amy Sau-Ching Ha
Asian Social Science , 2009, DOI: 10.5539/ass.v4n12p3
Abstract: The purpose of this article was to provide a review of the research on the professional development of physical education (PE) teachers. The structured approach (Erich, Hansford and Tennent, 2004) was used for the search and analysis of literature. First, searching through computerized education databases, a total of 56 research-based articles were included in this review. Second, demographic data were summarized and analyzed according to the geographic distribution, study periods, research method, research design, and participants. Third, a review and analysis of the findings from these studies were presented according to three themes: impact of PE teacher development, types of PE teacher development, and influencing factors. The article concluded with a discussion of key issues in three themes and the recommendation for the future research.
An Empirical Investigation of Competitive Exam Based Selection and Placement of Managerial Public Officials in Vietnam: Is It a Cure or a Curse?  [PDF]
Thai Thanh Ha, Ton Duc Sau
Modern Economy (ME) , 2018, DOI: 10.4236/me.2018.97077
Abstract: Competitive exams, selection, and placement of high-ranking public officials used to be resorted only by Vietnam’s feudal dynasties. After half a century of abandonment, this practice seems to have made its spectacular comeback in the recent decade. In a quest for high caliber public personnel, the Vietnamese government believes that competitiveness-base exams would help select, recruit and place right public servants into the right job. This research was conducted to figure out to what extent the selected high-ranking post holders were different from the public service employers. Based on face-to-face interviews with candidates and the heads of public services employers who were going to place the selected ones onto the managerial posts, data were gathered for Structural Equation Modeling (SEM) analysis with the use of structured 5 point-Likert scale questionnaire in the field surveys. Findings showed that there existed a difference in the perceptions towards the fairness of the competitive exams among these two types of interviewees. By comparing SEM coefficients, several recommendations were drawn for policy makers and managers to modernize this type of recruitment, selection and placement of managerial public servants on the intended job positions.
Changes in Bone Mineral Density through 96 Weeks in Antiretroviral-Naïve HIV-1 Infected Patients Receiving Abacavir/Lamivudine and Raltegravir in the SHIELD Trial  [PDF]
Linda Battalora, Amy Thomas, Brian Wine, Belinda Ha, Benjamin Young
World Journal of AIDS (WJA) , 2014, DOI: 10.4236/wja.2014.41005

Decreased bone mineral density (BMD) and osteoporotic fractures are areas of increasing concern among HIV-infected persons. Particular concern is the rapid decline in BMD after initiation of antiretroviral treatment (ART). This report describes DEXA-assessed changes in BMD and body fat in a study of fifteen antiretroviral-na?ve adults initiating abacavir/lamivudine and raltegravir for 96 weeks. Median percent changes from baseline at weeks 48 and 96 in BMD were 0.29% and -0.11% (spine); -1.25% and -1.75% (left hip). Median percent changes from baseline in fat from baseline were -0.82% and -3.04% (trunk); 2.12% and 2.01% (limb). In this pilot study, ABC/3TC + RAL treatment had limited impact on BMD and body fat.

Structure-Guided Design of an Engineered Streptavidin with Reusability to Purify Streptavidin-Binding Peptide Tagged Proteins or Biotinylated Proteins
Sau-Ching Wu, Sui-Lam Wong
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0069530
Abstract: Development of a high-affinity streptavidin-binding peptide (SBP) tag allows the tagged recombinant proteins to be affinity purified using the streptavidin matrix without the need of biotinylation. The major limitation of this powerful technology is the requirement to use biotin to elute the SBP-tagged proteins from the streptavidin matrix. Tight biotin binding by streptavidin essentially allows the matrix to be used only once. To address this problem, differences in interactions of biotin and SBP with streptavidin were explored. Loop3–4 which serves as a mobile lid for the biotin binding pocket in streptavidin is in the closed state with biotin binding. In contrast, this loop is in the open state with SBP binding. Replacement of glycine-48 with a bulkier residue (threonine) in this loop selectively reduces the biotin binding affinity (Kd) from 4×10?14 M to 4.45×10?10 M without affecting the SBP binding affinity. Introduction of a second mutation (S27A) to the first mutein (G48T) results in the development of a novel engineered streptavidin SAVSBPM18 which could be recombinantly produced in the functional form from Bacillus subtilis via secretion. To form an intact binding pocket for tight binding of SBP, two diagonally oriented subunits in a tetrameric streptavidin are required. It is vital for SAVSBPM18 to be stably in the tetrameric state in solution. This was confirmed using an HPLC/Laser light scattering system. SAVSBPM18 retains high binding affinity to SBP but has reversible biotin binding capability. The SAVSBPM18 matrix can be applied to affinity purify SBP-tagged proteins or biotinylated molecules to homogeneity with high recovery in a reusable manner. A mild washing step is sufficient to regenerate the matrix which can be reused for multiple rounds. Other applications including development of automated protein purification systems, lab-on-a-chip micro-devices, reusable biosensors, bioreactors and microarrays, and strippable detection agents for various blots are possible.
The Enjoyment of Physical Activity Determines Body Mass Index in Young People with Physical Disabilities  [PDF]
Shirley S. M. Fong, Amy S. C. Ha, Tina W. T. Chan, Mei K. Au
Open Journal of Preventive Medicine (OJPM) , 2014, DOI: 10.4236/ojpm.2014.45030

Objective: This study aimed to 1) compare the body mass index (BMI) and patterns of out-of-school activity participation in young people with and without physical disabilities, and 2) examine the relationship between BMI and the activity participation patterns among young people with physical disabilities. Methods: Thirty-nine young persons with physical disabilities (mean age ± standard deviation: 18.79 ± 1.99 years) and 70 healthy individuals (mean age ± standard deviation: 18.64 ± 0.74 years) participated in the study. The diversity, intensity, companionship, location and enjoyment of participation in activities were evaluated using the Children’s Assessment of Participation and Enjoyment (CAPE) scale. Body height and weight were obtained and BMI was calculated. Results: People with physical disabilities, regardless of their gender, had significantly lower CAPE-derived scores in almost all types of activity than the control participants (p < 0.05). Moreover, BMI was significantly higher in the group with physical disabilities than in the control group (p < 0.001). Regression analysis further showed that the CAPE score for physical activity explained 17.2% of the variance in BMI (p = 0.021). Conclusion: Young people with physical disabilities generally had lower levels of activity participation and a higher BMI than their healthy counterparts. The perception of enjoyment during physical activities was an important determinant of BMI in this group of participants.

A study on the international students’ perception and norms in Taiwan
Chou, Chuing Prudence,Roberts, Amy,Ching, Gregory S.
International Journal of Research Studies in Education , 2012,
Abstract: Trends in Taiwan higher education reflect traditional East Asian patterns, which show a substantial numbers of university students from Taiwan studying in the United States and Britain. In a recent worldwide student mobility report, findings suggest that an increased flow of international students coming from the United States and European countries to the Asia Pacific Rim is at an all time high. However, if the number of inbound international students’ is subtracted with the number of outgoing Asian students, results are still not that promising. Hence, in order to increase the influx of international students in Taiwan, a deeper understanding of their perceptions and norms should be undertaken. This article details a quantitative study conducted during the 2009–2010 academic year in Taiwan. In scope it details an empirical study exploring the dispositions of international students in terms of their academic and social spheres. The use of quantitative method provided clarity and extended critical interpretations of the issues and dilemmas surrounding the international student experience in Taiwan.
Non-vesicle-bound free microRNAs could enter cells and affect gene expression  [PDF]
Gang Wang, Ka-Bik Lai, Bonnie Ching-Ha Kwa, Kai-Ming Chow, Philip Kam-Tao Li, Cheuk-Chun Szeto
Advances in Bioscience and Biotechnology (ABB) , 2012, DOI: 10.4236/abb.2012.33026
Abstract: Background: Cell-free microRNAs (miRNAs) exist in body fluid. Previous studies showed that cell-free mi-RNAs are partly bound in microvesicles, and could transfer between cells via fusion with cell membrane. Methods: We quantified the amount of a panel of mi-RNA targets in and outside microvesicles in human proximal tubular epithelial cell (HK2) medium by microarray and real-time quantitative polymerase chain reaction (RT-QPCR). Intercellular miRNA transfer was explored by medium transfer experiments. Results: We identified a portion of cell-free miRNAs that exists as non-vesicle bound, truly naked form. More importantly, these non-vesicle bound free miRNA could transfer between cells and exert biological effects. By miRNA microarray, we showed that the expression of many miRNA targets in HK-2 cells were altered, either up- or down-regulated, after exposure to extrinsic free miRNAs. The miRNA-200 family was the most affected in our model, with a corresponding alteration in the messenger RNA expression of down-stream targets including ZEB1 and vimentin. Conclusion: Our results suggest that free miRNA may serve as an intercellular messenger, a phenomenon that needs further exploration.
Vesicle-bound and free microRNAs in spent cell culture medium and biological fluids  [PDF]
Gang Wang, Ka-Bik Lai, Bonnie Ching-Ha Kwan, Kai-Ming Chow, Philip Kam-Tao Li, Cheuk-Chun Szeto
Advances in Bioscience and Biotechnology (ABB) , 2012, DOI: 10.4236/abb.2012.38133
Abstract: Background: In addition to the control of gene transla- tion intra-cellularly, microRNAs (miRNAs) have been found to exist extracellularly. However, extracellular miRNA identified in previous studies were largely confined to microvesicles. It remains uncertain whether free extracellular miRNA exists. Methods: We quantify a panel of miRNAs (miRNA 200 family, miR-205, and miR-192) in spent culture medium of renal tubular epithelial cells, as well as serum and urine from patients with systemic lupus erythematosus and healthy controls. Microvesicle bound and free miRNA were separated by ultracentrifugation. Results: In spent cell culture medium, we found substantial amount of miR-200a, miR-200b, miR-200c, miR-141, miR-429, miR-205, and miR-192 in microvesicles, as well as the presence of miR-200a, miR-200b, miR-429, miR-205 and miR-192, but not miR-200c or miR-141 as non-vesicle bound free form. In healthy individuals, we found substantial amount of miR-200a, miR-200b, miR-200c, miR-141 and miR-192 in microvesicles from serum and urine, while only miR-141 exists as free form in both serum and urine. There was no significant difference in serum or urinary free miR-141 levels between SLE patients and healthy controls. In SLE patients, urinary free miR-141 level was signifiantly higher than serum. Neither serum nor urinary free miR-141 levels correlated with lupus disease activity. Conclusion: We found miRNA is present extracellularly, both within microvesicles and as free form, in spent cell culture medium, serum and urine. The biological role of extracellular miRNA requires further study.
A Note on Tetrablock Contractions
Haripada Sau
Mathematics , 2013,
Abstract: A commuting triple of operators $(A,B,P)$ on a Hilbert space $\mathcal{H}$ is called a tetrablock contraction if the closure of the set $$ E = \{\underline{x}=(x_1,x_2,x_3)\in \mathbb{C}^3: 1-x_1z-x_2w+x_3zw \neq 0 \text{whenever}|z| \leq 1\text{and}|w| \leq 1 \} $$ is a spectral set. In this paper, we have constructed a functional model and produced a complete unitary invariant for a pure tetrablock contraction. In this construction, the fundamental operators, which are the unique solutions of the operator equations $$ A-B^*P = D_PX_1D_P \text{and} B-A^*P=D_PX_2D_P, \text{where $X_1,X_2 \in \mathcal{B}(\mathcal{D}_P)$}, $$ play a big role. As a corollary to the functional model, we show that every pure tetrablock isometry $(A,B,P)$ on a Hilbert space $\mathcal{H}$ is unitarily equivalent to $(M_{G_1^*+G_2z}, M_{G_2^*+G_1z},M_z)$ on $H^2_{\mathcal{D}_{P^*}}(\mathbb{D})$, where $G_1$ and $G_2$ are the fundamental operators of $(A^*,B^*,P^*)$. We prove a Beurling-Lax-Halmos type theorem for a triple of operators $(M_{F_1^*+F_2z},M_{F_2^*+F_1z},M_z)$, where $\mathcal{E}$ is a Hilbert space and $F_1,F_2 \in \mathcal{B}(\mathcal{E})$. We deal with a natural example of tetrablock contraction on functions space to find out its fundamental operators.
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