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Serum Paraoxonase 1 Activity Is Associated with Fatty Acid Composition of High Density Lipoprotein
Maryam Boshtam,Amirnader Emami Razavi,Morteza Pourfarzam,Mohsen Ani,Gholam Ali Naderi,Gholam Basati,Marjan Mansourian,Narges Jafari Dinani,Seddigheh Asgary,Soheila Abdi
Disease Markers , 2013, DOI: 10.1155/2013/612035
Abstract: Introduction. Cardioprotective effect of high density lipoprotein (HDL) is, in part, dependent on its related enzyme, paraoxonase 1 (PON1). Fatty acid composition of HDL could affect its size and structure. On the other hand, PON1 activity is directly related to the structure of HDL. This study was designed to investigate the association between serum PON1 activity and fatty acid composition of HDL in healthy men. Methods. One hundred and forty healthy men participated in this research. HDL was separated by sequential ultracentrifugation, and its fatty acid composition was analyzed by gas chromatography. PON1 activity was measured spectrophotometrically using paraxon as substrate. Results. Serum PON1 activity was directly correlated with the amount of stearic acid and dihomo-gamma-linolenic acid (DGLA). PON1/HDL-C was directly correlated with the amount of miristic acid, stearic acid, and DGLA and was inversely correlated with total amount of ω6 fatty acids of HDL. Conclusion. The fatty acid composition of HDL could affect the activity of its associated enzyme, PON1. As dietary fats are the major determinants of serum lipids and lipoprotein composition, consuming some special dietary fatty acids may improve the activity of PON1 and thereby have beneficial effects on health. 1. Introduction Serum paraoxonase 1 (PON1) is a 45?kDa glycoprotein which can catalyze the hydrolysis of various organophosphates and nerve agents [1, 2] and also metabolize some drugs and prodrugs by its lactonase activity [3]. This enzyme which is located on high density lipoprotein (HDL) particles protects low density lipoprotein (LDL) phospholipids against oxidation [4]. Decreased PON1 activity has been addressed in several diseases such as coronary artery diseases (CAD) [5], type I diabetes [6], obesity [7], and renal failure [8]. It is evident that PON1 activity is influenced by a variety of agents like environmental, pharmacological, and lifestyle factors as well as age and sex [2, 5, 9–11]. Dietary fats have been suggested as an important relevant factor [12, 13]. Studies have presented that dietary fatty acids may affect PON1 activity [14]. Polyenoic fatty acids have shown considerable inhibitory effect on PON1 activity [15], while monoenoic acids (especially oleic acid) protect PON1 from oxidative inactivation [16]. It has been also indicated that replacement of dietary saturated fats with trans fats in healthy men and women leads to a small reduction in the serum PON1 activity [17]. Serum PON1 is almost exclusively found in association with HDL particles. The lipid
The Iranian Vital Horoscope; Appropriate Tool to Collect Health Statistics in Rural Areas
A Khosravi,ME Motlagh,SH Emami Razavi
Iranian Journal of Public Health , 2009,
Abstract: "nThis paper aims to describe the Iranian Vital Horoscope System. This system has been designed to collect and display vital events within the community. Baseline population data are collected by health workers (Behvarz), and are entered onto the Vi-tal Horoscope Chart. The objective of this data collection system is to compile relevant data to quantitatively assess the per-form-ance of the health unites at the different levels each year, according to conventional health indicators. Assessing in-di-ces reported based on this data sources confirmed the consistency of the Vital Horoscope as a data collection mechanism and provided face validity of the data source. However, further study is needed to evaluate content validity and reliability of data from this system.
A two-decade Review of Medical Ethics in Iran
F Zahedi,SH Emami Razavi,B Larijani
Iranian Journal of Public Health , 2009,
Abstract: "nThe growing developments in science and technology have raised ethical challenges which should practically be addressed by scientists, regulatory bodies and policy makers. Likewise, challenging issues of medical ethics have also drawn a great deal of academic attention in Iran. In other words, recent decades have been an occasion of considerable development for contemporary bioethics in Iran. At first, the ongoing initiatives to arrange the national and regional research ethics commit-tees and to compile the national strategic plan for medical ethics is worth mentioning. Currently, research ethics committees are actively established in the universities and research centers across the country. Furthermore, the subject of ethics in dif-ferent fields of science, which was followed in a traditional approach previously, is an important object of discussion cur-rently. Much research is now being undertaken in various areas of bioethics nationwide. Consequently, during the period under review, considerable articles and books have been published in the emerging subjects of bioethics. Several educa-tional workshops and courses have been frequently taken place in the universities and research centers. Foundation of aca-demic courses and fellowship in bioethics are also among the recent activities in the realm of medical ethics education in Iran. Likewise, considering several areas of bioethics that need legislation or reconsideration of previous regulations; the authorities, policy-makers, and scientists have carried out some endeavors to prepare appropriate law, codes, and guidelines. This report summarizes the bioethical activities and achievements in different fields of policy-making, organizing, teaching, and putting ethics into practice in our country during two recent decades.
Petrography, Temperature Measurement, and Economic Evaluation of Granitoid Pluton of Qohrud-Kashan Using EPMA, XRD, and XRF Analysis  [PDF]
Afshin Ashja Ardalan, Mina Khodadady, Mohammad Hashem Emami, Jamal Sheikh Zakariaie, Mohammad Hosein Razavi, Abdollah Yazdi
Open Journal of Geology (OJG) , 2014, DOI: 10.4236/ojg.2014.48032

The area which is being studied is located in northwest of Isfahan, 30 kilometers south of Kashan, and southern section of Qmasar. The longitude of the area of study is 51°19'13\"E to 51°26'26\"E and its latitude is 33°34'24\"N to 33°44'24\"N. Based on microscopic observations, modal analysis, and also based on their location in the Streckeisen [QAPF], both the stones of the Qohrud batholitic mass themselves and its enclaves are more in quartz monzonite ranges. Granitoid also have quartz monzonite enclaves. These enclaves are from both microgranular mafic and Autolith types which indicate the mixing of two magmas. At the center of the pluton, there are indications of existence of main magma reservoir and magma mixing. In terms of mineralogy, the granitoid rocks of the area very much resemble I-type. The zoning of the plagioclases is both the normal kind and variation invert and has andesine general composition. The probed biotite sample contains iron and belongs to a granitic sample from the center of the mass. Also, the ranking graph indicates biotite as the source of recrystallization for the analyzed points. The probed biotite sample of the Qohrud area showed formation temperature of 730 degrees centigrade. According to the Rb and Sr contents, the source of the rocks is at depths of 20 to 30 kilometers from the earth’s surface that are depending on the subduction zone. The formation temperature of the specimens of the Qohrud batholithic mass is mostly between 900 to 1000 degrees centigrade. [At] the center of the mass (around Qahrud), the amount of molybdenum is higher than the economic limit.

Mineral Chemistry and Thermobarometry of the Volcanic Rocks in Torud, Iran  [PDF]
Elham Shah Hosseini, Afshin Ashja Ardalan, Mohammad Hashem Emami, Mohammad Hossein Razavi
Open Journal of Geology (OJG) , 2014, DOI: 10.4236/ojg.2014.49033
Abstract: This paper elucidates the compositional studies on clinopyroxene, plagioclase of basalts to andesitic rocks of Torud area to understand the geotectonic and geothermobarometry conditions. Early Eocene-Oligocene calc-alkaline volcanic rocks are exposed around Torud in the Central Iranian zone. Volcanic rocks consist of basaltic, andesite basalt, Tracyandesite, and andesite. Minerals in the volcanic rocks exhibit degrees of disequilibrium features. Plagioclase as dominant mineral in these rocks generally displays oscillatory zoning. Mineral chemistry studies show that clinopyroxenes in the volcanic rocks are diopside, augite and plotted in medium pressure field. The clinopyroxene composition yields the crystallization temperatures 900°C - 1000°C. The mineral composition indicates that these rocks are formed in a tensional environment.
Properties of Fermion Spherical Harmonics
Geoffrey Hunter,Mohsen Emami-Razavi
Physics , 2005,
Abstract: The Fermion Spherical harmonics [$Y_\ell^{m}(\theta,\phi)$ for half-odd-integer $\ell$ and $m$ - presented in a previous paper] are shown to have the same eigenfunction properties as the well-known Boson Spherical Harmonics [$Y_\ell^{m}(\theta,\phi)$ for integer $\ell$ and $m$]. The Fermion functions are shown to differ from the Boson functions in so far as the ladder operators $M_+$ ($M_-$) that ascend (descend) the sequence of harmonics over the values of $m$ for a given value of $\ell$, do not produce the expected result {\em in just one case}: when the value of $m$ changes from $\pm{1/2}$ to $\mp{1/2}$; i.e. when $m$ changes sign; in all other cases the ladder operators produce the usually expected result including anihilation when a ladder operator attempts to take $m$ outside the range: $-\ell\le m\le +\ell$. The unexpected result in the one case does not invalidate this scalar coordinate representation of spin angular momentum, because the eigenfunction property is essential for a valid quantum mechanical state, whereas ladder operators relating states with different eigenvalues are not essential, and are in fact known only for a few physical systems; that this coordinate representation of spin angular momentum differs from the abstract theory of angular momentum in this respect, is simply an interesting curiosity. This new representation of spin angular momentum is expected to find application in the theoretical description of physical systems and experiments in which the spin-angular momentum (and associated magnetic moment) of a particle is oriented in space, since the orientation is specifiable by the spherical polar angles, $\theta$ and $\phi$.
The Most Common Cancers in Iranian Women
SH Emami Razavi,H Aaghajani,M Haghazali,F Nadali
Iranian Journal of Public Health , 2009,
Abstract: "nCancer is the third main cause of death in Iran. This report was provided for explaining most common cancers in Iranian Women. The National Cancer Registry reports from 2003 to 2006, pathologic based cancer registry reports from all of prov-inces of Iran. The age-standardized incidence rate of cancers was 56.80, 75.15, 6.18, 102.43 per 100 000 among fe-males in 2003, 2004, 2005, 2006, respectively. The male to female standard ratio was 1.12. The most common cancer among women was breast cancer. The cancer registration system, is the main tool of management and control of cancers and such impor-tant informa-tion source is not only necessary for epidemiologic studies of the illness, but also for planning and forecasting the events, measuring the accuracy of the studies, and the effects of medical interventions. Without a cancer registry with de-fined standards, we may not be able to formulate, execute, and observe any cancer control plan. According to the results, breast cancer is the most common cancer in Iranian females. Therefore, breast cancer screening should be start in Iran.
A new look at an old dogma: wound complications in two methods of skin closure in uncomplicated appendicitis
Hamid Ghaderi,Kourosh Shamimi,Fereydoon Moazzami,Seyed Hasan Emami razavi
Tehran University Medical Journal , 2010,
Abstract: "n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: Appendicitis is more common during the second and third decade of life and appendectomy scar is important in terms of cosmetic issues. The scar is an important factor in the patient's satisfaction. Conventional teaching has an emphasis on the closure of skin incision with "separate" sutures. The aim of this study was to reconsider this dogma."n"nMethods: Among 321 patients with acute appendicitis who came to the emergency unit of Imam Khomeini Hospital in Tehran, Iran since april 2007 till april 2008, 278 (86.6%) patients had uncomplicated appendicitis and were enrolled in our clinical trial. The patients were randomly assigned to two groups of interrupted suture closure (n=139) and subcuticular suture closure (n=139). Anesthesia method and surgical technique were similar between the two groups. All patients were followed up post-operatively (four weeks) for the presence of infectious drainage, pain, erythema, swelling and warmness at the surgical site."n"nResults: The patients' sex and their mean age were not statistically different between the groups. There was no significant difference in the frequency of surgical site complications between the two groups (five cases in the "interrupted" group and eight cases in the "subcuticular" group; p=0.415)."n"nConclusion: This study showed that appendectomy incision closure with subcuticular sutures did not increase the risk of wound complications. From the point of better cosmetic outcome of subcuticular sutures, this method may be the method of choice for the closure of appendectomy incisions in uncomplicated appendicitis.
Reporting of 100 cases of laparoscopic cholecystectomy in Imam Khomeini Hospital
Rabbani A,Mir Sharifi SR,Razavi Emami SH
Tehran University Medical Journal , 1995,
Abstract: 100 patients (93 females and 7 males) in ages ranging between 23 and 65 years were subjected to laparoscopic cholecystectomy for biliary colic (92 pts), acute cholecystitis (7 pts) or asymptomatic gallstones (1 pt). None had a history of icterus and in every case choledocholithiasis was excluded by means of serum alkaline phosphatase assessment and sonography (In addition to ERCP in 3 pts). 3 operations were converted to open cholecystectomy (Because of uncertainty about anatomy in 1 pt, extensive adhesions in 1 pt, and persistent bleeding in 1 pt). Mean operation time was 80 min. 90 patients were discharged on the 2nd post-operative day. Apart from 2 pts who were readmitted (For omental evisceration in 1 pt and sub hepatic hematoma in 1), complications were limited to minor complaints. Laparoscopic cholecystectomy is a safe procedure in the hands of a skilled surgeon who is aware of anatomic variations and is always prepared to liberally convert the operation to an open cholecystectomy.
Five-Year Survival Rate of Cutaneous Malignant Melanoma in Iran
N. Esmaili,M.A. Mohagegi,Z. Safayi Naraghi,S.Z. Emami Razavi,M. Chavoshi,S.H. Emami Razavi
Research Journal of Biological Sciences , 2012,
Abstract: Cutaneous Malignant Melanoma (CMM) is the most malignant type of skin cancers. The incidence and mortality rates of CMM are rising in almost all countries. This study was performed to investigate the 5-year survival rate of CMM in Iran and comparing these rates among sexes, different age groups, anatomical sites and clinical types of CMM. Patients diagnosed with CMM registered in Cancer Registry Center Tehran, Iran from 1998-2001 were included. The survival rate was assessed in those to whom phone call access was successful (78 patients). They were interviewed and a special questionnaire was filled. Other epidemiologic information was obtained from patient`s profiles in this center. The overall 5-yaer survival rate was 28.6% (p<0.05). The differences between sexes, different age groups and anatomical sites were not significant. The survival rate of CMM obtained in this study, is far lower than most countries. These results necessitates for health care system to plan an effective and comprehensive primary and secondary preventive programs based on education and increasing awareness of people and physicians. Although, more population based studies should be done to investigate more precise database.
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