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Search Results: 1 - 10 of 224018 matches for " Ami R. Vikani "
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Suprabasin Is Hypomethylated and Associated with Metastasis in Salivary Adenoid Cystic Carcinoma
Chunbo Shao,Marietta Tan,Justin A. Bishop,Jia Liu,Weiliang Bai,Daria A. Gaykalova,Takenori Ogawa,Ami R. Vikani,Yuri Agrawal,Ryan J. Li,Myoung Sook Kim,William H. Westra,David Sidransky,Joseph A. Califano,Patrick K. Ha
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0048582
Abstract: Salivary gland adenoid cystic carcinoma (ACC) is a rare cancer, accounting for only 1% of all head and neck malignancies. ACC is well known for perineural invasion and distant metastasis, but its underlying molecular mechanisms of carcinogenesis are still unclear.
Breast Implants for Graduation: A Sociological Examination of Daughter and Mother Narratives  [PDF]
Lori Ann Fowler, Ami R. Moore
Sociology Mind (SM) , 2012, DOI: 10.4236/sm.2012.21014
Abstract: The purpose of this research is to examine through sociological theories how young women and their parents make sense of the desire, attainment, and gifting of breast implants for graduation. A qualitative study of 10 high school graduates and their mothers was conducted in the state of Texas, USA, in order to understand why the daughters asked for implants as a graduation gift and why their parents, especially, mothers paid for them. Four theoretical paradigms provided a better understanding of the gifting and receiving of breast implants for graduation: symbolic interaction theory, the social construction of reality, reference group theory, and conspicuous consumption. This study shows that gifting and receiving implants for graduation is primarily motivated by both personal feelings of physical inadequacy and sociocultural representation of beauty.
Disclosure of Children's Positive Serostatus to Family and Nonfamily Members: Informal Caregivers in Togo, West Africa
Ami R. Moore,David Williamson
AIDS Research and Treatment , 2011, DOI: 10.1155/2011/595301
Abstract: This study examined the structural constraints to disclosure of children's positive serostatus among informal caregivers to family and nonfamily members in Togo. It drew on two data sources, one qualitative and the other quantitative. Qualitative data showed that caregivers cautiously disclosed child's positive serostatus for fear of being stigmatized and discriminated against as well as to protect the children from being stigmatized. Binary regression analyses revealed that different factors influenced reasons for disclosure of a child's serostatus. For instance, while caregivers' serostatus and number of children significantly influenced disclosure for financial support, disclosure of a child's serostatus for spiritual support was strongly affected by education and religion. These results shed light on factors and reasons for disclosure among caregivers. This knowledge is important because different types of programs and advice should be given to caregivers with specific reason(s) for disclosure instead of creating a “one-size-fits all” program for all caregivers. 1. Introduction Disclosure of positive HIV serostatus beyond the caregiver-patient dyad has been shown to vary according to many factors including education [1, 2], source of medical care [3], condom and alcohol use [4], religion [5], number of sexual partners [4], ethnicity [6], socioeconomic status [7], relationship to the one to whom the disclosure is made [6–10], and gender [4]. Although findings are somewhat inconsistent, most have found that disclosure is most likely when the target (one to whom the disclosure is made) is intimate or a close family member, when the discloser is a woman, is of lower socioeconomic status, is acculturated rather than a recent immigrant [6], uses condoms but does not use alcohol heavily before sex, and has fewer sexual partners. Of the factors inhibiting disclosure, the fear of stigmatization is among the most common [4, 6, 11]. Also commonly noted are the fear of abandonment, the loss of economic support, and the fear of violence from an intimate partner [3, 9]. One means of explaining the anomalies and inconsistencies in findings has been proposed by Brandt et al. [12], who argue that contextually grounded research aimed at illuminating individual-level strategic decisions is the best way to understand disclosure patterns. This methodological warning is consistent with the concerns of Vanlandingham et al. [13] that population-based studies of AIDS overlook the contextually rich community and individual-level realities in which disclosure decisions are
Loneliness of the Marginalized  [PDF]
Ami Rokach
Open Journal of Depression (OJD) , 2014, DOI: 10.4236/ojd.2014.34018
Abstract: This review article provides a bird’s eye view of several population groups that are marginalized, ostracized, and stigmatized. Those include the homeless, the physically disabled, and psychiatric patients, Lesbian, Gay, Bisexual and Transgender (LGBTs), and those afflicted with Human immunodeficiency Virus (HIV) or with Acquired Immunodeficiency Syndrom (AIDS). Their condition, how it leads to social isolation and loneliness, and its effects on them, their illness or condition, and their quality of life are described. Interestingly, while all experience loneliness, each group expresses and addresses it differently. Awareness of those unique expressions of loneliness could assist mental health workers in identifying, addressing, and helping the marginalized cope with loneliness.
Effective Coping with Loneliness: A Review  [PDF]
Ami Rokach
Open Journal of Depression (OJD) , 2018, DOI: 10.4236/ojd.2018.74005
Abstract: Loneliness has been part of the human experience since the beginning of time. It cannot be avoided, but we may be able to cope with it, address its pain and possibly lower its frequency in our lives. This review addresses the theoretical approaches, and the author’s own research which aims at exploring various means of coping with loneliness.
Code Clone Detection Method Based on the Combination of Tree-Based and Token-Based Methods  [PDF]
Ryota Ami, Hirohide Haga
Journal of Software Engineering and Applications (JSEA) , 2017, DOI: 10.4236/jsea.2017.1013051
Abstract: This article proposes the high-speed and high-accuracy code clone detection method based on the combination of tree-based and token-based methods. Existence of duplicated program codes, called code clone, is one of the main factors that reduces the quality and maintainability of software. If one code fragment contains faults (bugs) and they are copied and modified to other locations, it is necessary to correct all of them. But it is not easy to find all code clones in large and complex software. Much research efforts have been done for code clone detection. There are mainly two methods for code clone detection. One is token-based and the other is tree-based method. Token-based method is fast and requires less resources. However it cannot detect all kinds of code clones. Tree-based method can detect all kinds of code clones, but it is slow and requires much computing resources. In this paper combination of these two methods was proposed to improve the efficiency and accuracy of detecting code clones. Firstly some candidates of code clones will be extracted by token-based method that is fast and lightweight. Then selected candidates will be checked more precisely by using tree-based method that can find all kinds of code clones. The prototype system was developed. This system accepts source code and tokenizes it in the first step. Then token-based method is applied to this token sequence to find candidates of code clones. After extracting several candidates, selected source codes will be converted into abstract syntax tree (AST) for applying tree-based method. Some sample source codes were used to evaluate the proposed method. This evaluation proved the improvement of efficiency and precision of code clones detecting.
Effects of Acute Psychosocial Stress on Facial Emotion Recognition  [PDF]
Efrat Barel, Ami Cohen
Psychology (PSYCH) , 2018, DOI: 10.4236/psych.2018.93025
Abstract: Accurate recognition of the emotions of other people is essential for successful human interactions. Previous studies showed inconsistent results of the impact of acute psychosocial stress on emotion recognition. Thus, the present study aimed at investigating the influence of psychosocial stress on the recognition of facial emotional expressions of different valance. Eighty-eight participants were randomly assigned to one of two experimental groups: stress (exposure to the Trier Social Stress Test) and control. Participants of both groups completed a facial emotion recognition test before and after the manipulation. The results demonstrated an enhancement in emotion recognition in the stress group but not in controls. Further analyses revealed that while stress enhanced the accurate recognition of anger, happiness, surprise, and neutral/calmness, it impaired the recognition of fear and had no effect on the recognition of sadness and disgust. The findings are discussed in light of evolutionary assumptions regarding differential processing mechanisms of emotion expressions.
The Impact of Assisted Reproduction on Socio-Cultural Values and Social Norms  [PDF]
Steven R. Lindheim, Kathryn Coyne, Leslie Ayensu-Coker, Kathleen O’Leary, Stephanie Sinn, Ami S. Jaeger
Advances in Anthropology (AA) , 2014, DOI: 10.4236/aa.2014.44025
Abstract: Since the birth of the first “test tube” baby, the use of in vitro fertilization (IVF) has undergone an enormous metamorphosis. Initially designed for blocked fallopian tubes, IVF has found a number of other clinical applications over the past 40 years. However, as the science has advanced, traditional norms of conception and parenthood have been challenged and reproductive health ethics, guidelines, and law struggle to keep pace. Controversies and debates have arisen within the law, public policy, and the meaning of family across societies and religious sects. This paper will highlight some of the current and complex social, moral, and legal questions surrounding the implementation and advancement of assisted reproduction including Cross Border Reproductive Care, Oocyte Donation and Consents, Oncofertility, Posthumous Reproduction raising fresh discussion and debate.
Self-reported chemicals exposure, beliefs about disease causation, and risk of breast cancer in the Cape Cod Breast Cancer and Environment Study: a case-control study
Ami R Zota, Ann Aschengrau, Ruthann A Rudel, Julia Brody
Environmental Health , 2010, DOI: 10.1186/1476-069x-9-40
Abstract: Participants were 787 Cape Cod, Massachusetts, women diagnosed with breast cancer between 1988 and 1995 and 721 controls. Telephone interviews asked about product use, beliefs about breast cancer etiology, and established and suspected breast cancer risk factors. To evaluate potential recall bias, we stratified product-use odds ratios by beliefs about whether chemicals and pollutants contribute to breast cancer; we compared these results with odds ratios for family history (which are less subject to recall bias) stratified by beliefs about heredity.Breast cancer risk increased two-fold in the highest compared with lowest quartile of self-reported combined cleaning product use (Adjusted OR = 2.1, 95% CI: 1.4, 3.3) and combined air freshener use (Adjusted OR = 1.9, 95% CI: 1.2, 3.0). Little association was observed with pesticide use. In stratified analyses, cleaning products odds ratios were more elevated among participants who believed pollutants contribute "a lot" to breast cancer and moved towards the null among the other participants. In comparison, the odds ratio for breast cancer and family history was markedly higher among women who believed that heredity contributes "a lot" (OR = 2.6, 95% CI: 1.9, 3.6) and not elevated among others (OR = 0.7, 95% CI: 0.5, 1.1).Results of this study suggest that cleaning product use contributes to increased breast cancer risk. However, results also highlight the difficulty of distinguishing in retrospective self-report studies between valid associations and the influence of recall bias. Recall bias may influence higher odds ratios for product use among participants who believed that chemicals and pollutants contribute to breast cancer. Alternatively, the influence of experience on beliefs is another explanation, illustrated by the protective odds ratio for family history among women who do not believe heredity contributes "a lot." Because exposure to chemicals from household cleaning products is a biologically plausible cause
Stability Indicating Liquid Chromatographic Method for Estimation of Trihexyphenidyl Hydrochloride and Risperidone in Tablet Formulation: Development and Validation Consideration
Patel Bhaumik,Gopani Mehul,Vikani Kartik,Patel Rashmin,Patel Mrunali
Chromatography Research International , 2014, DOI: 10.1155/2014/523184
Abstract: This paper describes validated reverse phase high-performance liquid chromatographic (RP-HPLC) method for simultaneous estimation of trihexyphenidyl hydrochloride (THP) and risperidone (RSP) in the pure powder form and in combined tablet dosage form. The HPLC separation was achieved on a core shell C18 (100?mm length?×?4.6?mm, 2.6?μm particle size) using methanol : ammonium acetate buffer 1% (85?:?15 v/v; pH-6.5) as mobile phase and delivered at flow rate of 0.8?mL/min. The calibration plot showed good linear relationship with r2 = 0.997 ± 0.001 for THP and r2 = 0.998 ± 0.001 for RSP in concentration range of 50–175?μg/mL and 50–175?μg/mL, respectively. LOD and LOQ were found to be 0.40 and 1.29?μg/mL for THP and 1.24 and 3.92?μg/mL for RSP. Assay of THP and RSP was found to be 100.16?±?0.03% and 99.83?±?0.02%, respectively. THP and RSP were subjected to different stress conditions (acidic, basic, oxidative, thermal, and photolytic degradation). The degraded product peaks were well resolved from the pure drug peak. The method was successfully validated as per the ICH guidelines. The developed RP-HPLC method was successfully applied for the estimation of THP and RSP in tablet dosage form. 1. Introduction Trihexyphenidyl hydrochloride, chemically known as 1-cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol, is one of the centrally acting muscarinic antagonists used for the treatment of parkinsonian disorders and drug-induced extrapyramidal movement disorders and as an antispasmodic. Risperidone (RSP), chemically known as 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl) piperidin-1-yl]ethyl}-2-methyl-4H, 6H, 7H, 8H, 9H-pyrido [ -a] pyrimidin-4-one, is benzisoxazole derivative and an atypical antipsychotic drug with high affinity for 5-hydrotryptamine (5-HT) and dopamine D2 receptors. It is used primarily in the management of schizophrenia, inappropriate behaviour in severe dementia, and manic episodes associated with bipolar I disorder. RSP is effective in treating the positive and negative symptoms of schizophrenia owing to its affinity for its “loose” binding affinity for dopamine D2 receptors and additional 5-HT antagonism compared to first generation antipsychotics, which are strong, nonspecific dopamine D2 receptor antagonists. Both trihexyphenidyl hydrochloride (THP) and RSP are official in pharmacopoeia. A literature survey revealed that high-performance liquid chromatography (HPLC) for determination of THP and RSP in tablet [1–3] was reported. Further, HPLC method for estimation of RSP in plasma [4], bulk drug and pharmaceutical formulation [5], tablet
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