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Search Results: 1 - 10 of 50868 matches for " Alyssa Silva "
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Dean Winchester: An Existentialist Hero?
Alyssa Silva
Sesión no Numerada : Revista de Letras y Ficción Audiovisual , 2012,
Abstract: The popular show Supernatural, in particular the character of Dean Winchester, provides an interesting examination of freedom of choice. In fact Supernatural proves itself amenable to an existentialist reading of law, in particular the existentialism of Jean Paul Sartre. After a brief introduction to the show, the elements of Sartre’s existentialism I will be developing in this paper include freedom, choice and authenticity. These elements combine to demonstrate the existentialist law favoured by Dean, whereby Dean’s scepticism of God allows for an authenticity that furthers his own autonomy. The patterning trope of two brothers is essential to Dean developing his own law and morality separate from the divine one that is imposed on him throughout the show, with natural law showcasing that there is more than one kind of existentialist law to choose from.
Patterns of Refugee Planning: A Comparative Analysis of Current Refugee Planning Approaches  [PDF]
Alyssa M. Wissel
Advances in Applied Sociology (AASoci) , 2017, DOI: 10.4236/aasoci.2017.711023
Abstract: In 2015, there were more than 21 million refugees globally; as conflicts continue and globalization expands, it is advantageous for planners to strategically manage population influxes of ill-equipped families. Refugee policy decisions have imperative effects on housing markets, economies, segregation, international relations, and refugees’ resilience. Bound by the 1967 Protocol on the Status of Refugees, every member state is obligated to protect refugees. This paper analyzes the varying conditions of refugees in the top six countries with the highest number of refugees; through a matrix, this paper compares what attributes promote effective refugee plans and which do not. Every conflict scenario is unique, and there are attributes that a refugee plan cannot change (length of conflict, host country’s economy, status of host country’s government, cultural clashes between local population and refugees). However, this paper seeks to empower planners to use policy in ways they can mitigate current and future refugee situations. This analysis concludes that refugee policies work best for the host country and the refugees when refugees: 1) are able to live outside of camps and in cities; 2) can be employed; 3) are distributed to not overwhelm housing/infrastructure; and there are multiple funding sources.
Understory Recovery in Coast Redwood Communities: A Case Study Comparing a Naturally Recovering and an Actively Managed Forest  [PDF]
Alyssa Hanover, Will Russell
Open Journal of Forestry (OJF) , 2018, DOI: 10.4236/ojf.2018.84031
Abstract: Restoration of late seral features in second growth Sequoia sempervirens (coast redwood) forests is increasingly important, as so little of the original old-growth remains. Natural recovery is an effective method restoring many late seral features, and does not require the additional disturbance of active management. In order to better understand management impacts on redwood understory abundance and composition, data were collected in naturally recovering stands and in stands that were actively managed with the explicit intent of promoting old-growth characteristics. Ten 10 m diameter plots with three 2 m diameter nested sub-plots were randomly sampled in two sites within each management type. Results indicate that tree canopy cover, native species cover and richness, richness of coast redwood associated species, and the cover of Trillium ovatum (western wake robin) were significantly higher in naturally recovering versus actively managed stands. In addition, several coast redwood associated understory species were exclusively recorded in the naturally recovering stands including: Asuram caudatum (wild ginger), Prosartes hookeri (hooker’s fairybells), Maianthemum racemosum (false solomon seal), Scoliopus bigelovii (fetid adder’s tongue), Viola sempervirens (redwood violet); while only one such species was recorded exclusively in the actively managed stands: Trientalis latifolia (pacific star flower). Natural recovery appeared to support understory recovery more effectively than active forest management in this case.
Effects of healthy aging on human primary visual cortex  [PDF]
Alyssa A. Brewer, Brian Barton
Health (Health) , 2012, DOI: 10.4236/health.2012.429109
Abstract: Aging often results in reduced visual acuity from changes in both the eye and neural circuits [1-4]. In normally aging subjects, primary visual cortex has been shown to have reduced responses to visual stimulation [5]. It is not known, however, to what extent aging affects visual field repre-sentations and population receptive sizes in human primary visual cortex. Here we use func-tional MRI (fMRI) and population receptive field (pRF) modeling [6] to measure angular and ec-centric retinotopic representations and population receptive fields in primary visual cortex in healthy aging subjects ages 57 - 70 and in healthy young volunteers ages 24 - 36 (n = 9). Retinotopic stimuli consisted of black and white, drifting checkerboards comprising moving bars 11 deg in radius. Primary visual cortex (V1) was clearly identifiable along the calcarine sulcus in all hemispheres. There was a significant decrease in the surface area of V1 from 0 to 3 deg eccentricity in the aging subjects with respect to the young subjects (p = 0.039). The coherence of the fMRI% BOLD modulation was significantly decreased in the aging subjects compared to the young subjects in the more peripheral eccentricity band from 7 to 10 deg (p = 0.029). Finally, pRF sizes were significantly increased within the 0 to 3 deg foveal representation of V1 in the aging subjects compared to the young subjects (p = 0.019). Understanding the extent of changes that occur in primary visual cortex during normal aging is essential both for understanding the normal aging process and for comparisons of healthy, aging subjects with aging patients suffering from age-related visual and cortical disorders.
Visual Working Memory in Human Cortex  [PDF]
Brian Barton, Alyssa A. Brewer
Psychology (PSYCH) , 2013, DOI: 10.4236/psych.2013.48093

Visual working memory (VWM) is the ability to maintain visual information in a readily available and easily updated state. Converging evidence has revealed that VWM capacity is limited by the number of maintained objects, which is about 3 - 4 for the average human. Recent work suggests that VWM capacity is also limited by the resolution required to maintain objects, which is tied to the objects’ inherent complexity. Electroencephalogram (EEG) studies using the Contralateral Delay Activity (CDA) paradigm have revealed that cortical representations of VWM are at a minimum loosely organized like the primary visual system, such that the left side of space is represented in the right hemisphere, and vice versa. Recent functional magnetic resonance imaging (fMRI) work shows that the number of objects is maintained by representations in the inferior intraparietal sulcus (IPS) along dorsal parietal cortex, whereas the resolution of these maintained objects is subserved by the superior IPS and the lateral occipital complex (LOC). These areas overlap with recently-discovered, retinotopically-organized visual field maps (VFMs) spanning the IPS (IPS-0/1/2/3/4/5), and potentially maps in lateral occipital cortex, such as LO-1/2, and/or TO-1/2 (hMT+). Other fMRI studies have implicated early VFMs in posterior occipital cortex, suggesting that visual areas V1-hV4 are recruited to represent information in VWM. Insight into whether and how these VFMs subserve VWM may illuminate the nature of VWM. In addition, understanding the nature of these maps may allow a greater investigation into individual differences among subjects and even between hemispheres within subjects.

Long-axis rotational volvulus in an ileal J-pouch anal anastomosis: A preventable rare complication  [PDF]
Virgilio V. George, Alyssa Fajardo
Case Reports in Clinical Medicine (CRCM) , 2014, DOI: 10.4236/crcm.2014.31007

Puropose: This study was designed to report a very rare long-term complication of ileal-Jpouch anal anastomosis: An 180 degree longaxial rotational volvulus causing J pouch obstruction. Methods: An Ovid and Medline search using the following keywords was performed: J pouch ileoanal anastomosis, J-pouch ileoanal anastomosis complications, J-pouch volvulus, J-pouch complications, restorative proctocolectomy complications, and restorative proctocolectomy volvulus. One J-pouch ileoanal anastomosis 180° volvulus report was found [1]. Result: We describe a long-axis 180° rotational volvulus complication of a J-pouch ileoanal anastomosis. The J pouch was performed three years prior after the laparoscopic total proctocolectomy for chronic ulcerative colitis. Pouch excision and new ileoanal J-pouch surgery were then performed along with pexy using alloderm mesh placement with excellent outcomes. Conclusion: Long-axis 180° rotational volvulus is a rare complication of a J-pouch ileoanal anastomosis. Pouch dysfunction after a long-axis rotational volvulus is an uncommon cause of acute abdomen. Lack of adhesions and pouch size are risk factors for the pouch torsion. Prompt diagnosis and treatment are essential for the pouch salvage. Simple abdominal x-ray, barium enema and CT scan represent important tools for diagnosis. Salvage surgery should be performed even if detorsion and decompression of the affected bowel are achieved. Surgery has excellent outcomes if performed after the prompt diagnosis. Pouch pexy should be done to prevent recurrent volvulus.

Making it Work: Surviving as a Librarian Employed in Another Field
Alyssa Vincent
In the Library with the Lead Pipe , 2013,
Abstract: In Brief: On average, it takes approximately five months for LIS graduates to find a library job, according to Library Journal’s 2012 Placements and Salaries Survey (Matta 2012). This time frame represents the experience of 34% of 2011 graduates, but stories of months- or year-long job searches are common (Weak 2012). While some can afford [...]
Seeing Science
Alyssa Goodman
Physics , 2009,
Abstract: The ability to represent scientific data and concepts visually is becoming increasingly important due to the unprecedented exponential growth of computational power during the present digital age. The data sets and simulations scientists in all fields can now create are literally thousands of times as large as those created just 20 years ago. Historically successful methods for data visualization can, and should, be applied to today's huge data sets, but new approaches, also enabled by technology, are needed as well. Increasingly, "modular craftsmanship" will be applied, as relevant functionality from the graphically and technically best tools for a job are combined as-needed, without low-level programming.
EGFR Signaling in Colorectal Carcinoma
Alyssa M. Krasinskas
Pathology Research International , 2011, DOI: 10.4061/2011/932932
Abstract: The epidermal growth factor receptor (EGFR) and its downstream signaling pathways are involved in the development and progression of several human tumors, including colorectal cancer. Much attention has been given to the EGFR pathway as of lately because both EGFR and some downstream components serve as targets for anticancer therapy. In addition to playing a critical role in targeted therapy, alterations in this pathway can have prognostic implications. The EGFR pathway and its impact on colorectal carcinogenesis and prognosis are the emphasis of this paper. Since prognosis is tightly related to response to various therapies, the predictive value of the components of this pathway will be briefly discussed, but this is not the focus of this paper. 1. Introduction The epidermal growth factor receptor (EGFR) and its downstream signaling pathways regulate key cellular events that drive the progression of many neoplasms. EGFR is expressed in a variety of human tumors, including gliomas and carcinomas of the lung, colon, head and neck, pancreas, breast, ovary, bladder, and kidney. Mutations, gene amplification, and protein overexpression of various elements of this pathway not only contribute to carcinogenesis but also impact prognosis and provide specific targets for therapeutic intervention. The importance of EGFR and its signaling pathway in colorectal carcinogenesis is the topic of this paper. Since prognosis is tightly related to response to various therapies, the predictive value of the components of this pathway will be discussed, but only briefly. There is another paper in this series, “Impact of KRas mutations on management of colorectal cancer” by Sullivan and Kozuch, which provides an in-depth review of the predictive value of KRas and other members of the EGFR signaling pathway. 2. EGFR and the EGFR Signaling Pathway EGFR is a 170-kDa transmembrane tyrosine kinase receptor that belongs to the ErbB family of cell membrane receptors. In addition to EGFR (also known as HER1 and ErbB-1), other receptors in this family include HER2/c-neu (ErbB-2), Her 3 (ErbB-3), and Her 4 (ErbB-4). All of these receptors contain an extracellular ligand-binding region, a single membrane-spanning region, and a cytoplasmic tyrosine-kinase-containing domain. In normal cells, the EGFR signaling cascade begins with ligand activation of EGFR (Figure 1). Up to eleven ligands can bind the ErbB family of receptors, including EGF and transforming growth factoralpha [1]. Ligand binding induces dimerization of the receptor with formation of homodimers and heterodimers, which
Global citizenship and the Stanford Cross-Cultural Rhetoric
Alyssa J. O’BRIEN
Journal of the NUS Teaching Academy , 2011,
Abstract: Today, more than ever, in the current climate of intensified globalisation, students need the opportunity to learn concrete strategies for communicating and collaborating with others around the globe. Universities have increased mandates for internationalisation and the development of global citizens. Yet too often students lack access to technologically-mediated learning environments, and they do not have the chance to work regularly with transnational audiences. Thus, they do not learn how to work collaboratively on multimedia texts with others from diverse cultures. These, however, are the very skills and core competencies that students will need in their future professions and in their futures as global citizens. This article discusses the emergence of global citizenship as a key concern in higher education and shares lessons in classroom practice from the Stanford Cross-Cultural Rhetoric Project (CCR), a research endeavour and sustainable teaching programme connecting university students and teachers across multiple countries. The mission of the CCR project is to prepare students for effective collaboration and communication in global contexts, both within educational institutions and beyond. This article discusses the Stanford protocol, presents an overview of technology used for global connections, reviews research responses from assessment surveys, and concludes by discussing the emergent theoretical insights and recommendations for a pedagogical focus on three core competencies crucial for global citizenship in the technological age.
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