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Isolated duodenal rupture due to blunt abdominal trauma
Celik Atilla,Altinli Ediz,Onur Ender,Sumer Aziz
Indian Journal of Critical Care Medicine , 2006,
Abstract: Duodenal rupture following blunt abdominal trauma is rare and it usually seen with other abdominal organ injuries. It represents approximately 2% to 20% of patients with blunt abdominal injury and often occurs after blows to the upper abdomen, or abdominal compression from high-riding seat belts. Two cases of blunt duodenal rupture successfully treated surgically, are presented with their preoperative diagnosis and final out comes.
Surgical treatment of benign nodular goiter; report of 72 patients
Dicle Medical Journal , 2009,
Abstract: Surgical resection is usually prefered for the treatment of benign nodular goiter. But the extention of thyroidectomy in the surgical management of benign nodular goiter still remains controversial. Seventytwo patients underwent thyroid surgery between April 2002- July2007 in K z ltepe State Hospital Otorhinolaryngology Service. Of the patients 63 were women (%87.5), 9 were man (%12.5). The range of age was between 15-62 years and mean age was 36,5. Thirtynine patients had unilateral total lobectomy+ istmusectomy (%54.2), 11 patients had unilateral lobectomy+ isthmusectomy+contralateral subtotal lobectomy (Dunhill Procedure) (%15.3), 20 patients had nearly total thyroidectomy (%27.8), 2 patients had total thyroidectomy (% 2.7). Three patients had seroma (%4.1), 2 patients had hemorrhage requiring operative hemostasis (%2.7), 1 patient had suture reaction(%1.3). Patients have not had permanent or temporary nervus laryngeus recurrens injury, hypoparathyroidism and infection.As a result more extent surgical resections must be preferred by the surgeon for the treatment of benign nodular goiter. The preferable surgical treatment of solitary nodules is lobectomy+isthmusectomy. The multinodular goiter must be treated with unilateral lobectomy+ isthmusectomy+contralateral subtotal lobectomy (Dunhill procedure) when the remnant thyroid tissue is normal; otherwise nearly total or total thyroidectomy is preferable.
Endocrine Disruptors
Ediz Ye?ilkaya
Güncel Pediatri , 2008,
Abstract: Endocrine disruptors are of special interest because they mimic, block, or in some way alter the activity of endogenous chemicals that are synthesized by the endocrine system. Besides many other organs, they especially affect the urinary system and the thyroid glands. Endocrine-disrupting chemicals are typically identified as compounds that can interact with oestrogen or androgen receptors and thus act as agonists or antagonists of endogenous hormones. During the last decade, numerous studies have been published, reporting an increase in reproductive organ anomalies, as well as in testicular cancer, and a decline in the relative number of male births, and in semen quality. In this review, the effects of endocrine distruptors on the reproductive health are discussed in the light of the recent literature. (Journal of Current Pediatrics 2008; 6: 76-82)
Ectopic Intranasal Tooth
Ediz Yorganc?lar
Dicle Medical Journal , 2008,
Abstract: The intranasal tooth is a rare clinical phenomenon that has unclear etiology. It may result to rhinolith with deposition calcium and organic materials around the ectopic nasal tooth. In this report we presended 43-year-old female who had ectopic nasal tooth which seems to be rhinolith .Diagnose of ectopic nasal tooth was determined by radiological examination and it was extracted by endoscopically.
Von Willebrand hastal ’nda oral cerrahi yakla m: olgu sunumu
Ediz Deniz,Ahmet Arslan
Cumhuriyet Dental Journal , 2011, DOI: 10.7126/cdj.2012.1161
Abstract: Von Willebrand Disease (VWD) is a hereditary coagulation disorder characterized by a deficient or abnormal plasma protein known as the von Willebrand factor (vWF). Patients with VWD usually manifest a dual hemostatic defect characterized by a prolonged bleeding time and low plasma levels of Factor VIII coagulant activity. In the present case, management of 39 years old female patient with VWD in whom cryoprecipitate transfusion was applied for multiple tooth extractions was reported and alternative treatment protocols were discussed. ZET Von Willebrand Hastal (VWH), von Willebrand fakt r (vWF) olarak bilinen plazma proteinin yetersiz ya da anormal ekilde bulunmas ile karakterize herediter koagülasyon bozuklu udur. VWH olan hastalar, genellikle uzam kanama zaman ve Fakt r VIII koagülasyon aktivitesinin dü ük plazma de erleri ile karakterize ikili bir hemostatik defekte sahiptirler. Bu olgu raporunda, klini imize VWH tan s ile ba vuran 39 ya ndaki bayan hastan n, kriyospitat replasman tedavisi ile oklu di ekimleri ger ekle tirilip, alternatif tedavi protokolleri tart lm t r. Anahtar kelimeler: Von Willebrand Hastal , di ekimi
Epidermoid Cyst of the Testis 5-Year Follow-Up Results in Adults  [PDF]
Caner Ediz, Aysenur Ihvan, Bulent Kati, Serkan Akan, Omer Yilmaz
Open Journal of Urology (OJU) , 2019, DOI: 10.4236/oju.2019.94008
Abstract: Background: In this study, we aimed to share our experiences in patients with epidermoid cyst of the testis. We report the demographic and clinical characteristics and the long term results in patients with epidermoid cysts. Materials and Methods: Thirteen patients with epidermoid cyst of the testis treated between June 2000 and January 2018 were retrospectively evaluated. Ten patients with available data were included in the study. Patients’ age, scrotal localization of symptoms, physical examination findings, serum tumor marker levels, pathology results and follow-up periods were recorded. Results: The current cohort consisted of 10 patients. The mean age at diagnosis was 29.7 years (range, 20 to 53 years). Eighty percent of the lesions were localized to the left hemiscrotum and 20% to the right hemiscrotum. One patient had a history of unilateral undescended testis. Serum tumor markers were normal in all patients. The mean scrotal mass lesion volume at diagnosis was 28 mm3 (range, 13 to 51 mm3). The mean follow-up period was 66.9 months (range, 12 to 216 months). Conclusions: Epidermoid cyst of the testis should be kept in mind, particularly in patients with lesions negative for tumor markers and radiological findings typical of epidermoid cysts. Annual follow-up is not required.
Claudin 3 and 4 Immunoreactivity in Malign Mesothelioma and Lung Adenocarcinoma
?ule EK?Z,Ediz TUTAR
Türk Patoloji Dergisi , 2009,
Abstract: Objective: The differential diagnosis of malignant pleural mesotheliomas and lung adenocarcinomas is problematic for pathologists especially in small biopsy materials. In this study, we aimed to investigate whether the immunohistochemically determined Claudin 3 and Claudin 4 immunoreactivities are useful in the differential diagnosis between malignant pleural mesotheliomas and lung adenocarcinomas.Material and Method: Using the epitope-specific rabbit antibody Claudin 3 and Claudin 4, 32 cases of malignant pleural mesothelioma (25 epithelioid, 7 biphasic) and 14 cases of lung adenocarcinoma were studied immunohistochemicallyResults: None of the cases of malignant pleural mesotheliomas expressed Claudin 4, whereas all lung carcinomas were immunopositive. Claudin 3 expression was immunonegative in 29 (90.6%) cases and immunopositive in 3 (9.3%) cases of malignant pleural mesothelioma. With Claudin 3, 11/14 (78.9%) lung adenocarcinomas and 3/32 (9.4%) malignant pleural mesotheliomas were immunopositive (p=0.000).Conclusion: In conclusion, Claudin 4 antibody was found to be a highly sensitive and specific marker for distinguishing between malignant pleural mesothelioma and lung adenocarcinoma.
Symptom Modifying Effect Of Colchicine In Patients With Knee Osteoarthritis
Levent Ediz,?brahim Tekeo?lu
Journal of Clinical and Analytical Medicine , 2012, DOI: 10.4328
Abstract: Aim: The aim of this study was to investigate and evaluate symptom modifying effects of colchicine in patients with primary knee osteoarthritis over a 6- month period. Material and Method: Total 74 cases with primary knee osteoarthritis (between 40-75 years old, 52 female, 22 male) included the study. Patients assigned randomly into two groups to receive acetaminophen 3000 mg/day or acetaminophen 3000 mg/day plus colchicine 1.5 gr/day for six months. 5 female and 4 male patients withdrew the study because of lost to follow up after six month treatment. No patient discontinued the study because of drug adverse effects. Result: When compared with paired t test, before therapy (bt) WOMAC scores and VAS scores versus visit 1 (v1-1,5. month after initiation of therapy), visit 2 (v2- 3. month after initiation of therapy), visit 3 (v3-4,5. month after initiation of therapy), and visit 4 (v4-6. month after initiation of therapy) WOMAC scores and VAS scores, there was a statistically significant decrease of scores (p
Effect of Colchicine on Total Antioxidant Capacity, Antioxidant Enzymes and Oxidative Stress Markers in Patients with Knee Osteoarthritis  [PDF]
Metin Erden, Levent Ediz, ?zcan H?z, Yasin Tuluce, Halil Ozkol, Murat Toprak, Fahrettin Demirdag
International Journal of Clinical Medicine (IJCM) , 2012, DOI: 10.4236/ijcm.2012.35071
Abstract: Background/Aim: We aimed to investigate the effects of colchicine on clinical recovery, as well as oxidative stress markers and total antioxidant capacity (TAC) in whole blood of patients with knee osteoarthritis (OA). Materials and methods: Sixty patients with grade 2 - 3 knee OA according to ACR knee OA criteria whom examination of the knee joint synovial fluid by polarized light microscopy demonstrated CPDD crystals existence were included in the study. Fifty healthy subjects were included as a control group. Patients were divided randomly into two groups. The first group (paracetamol group) was given only paracetamol 3 gr daily p.o and the second group (colchicine and paracetamol group) was given colchicine 1,5 gr and paracetamol 3 gr daily p.o for six months. For outcome measures WOMAC and VAS were used. Superoxide dismutase (SOD), Catalase (CAT) ezyme activities and Glutathione (GSH) and Malondialdehyde (MDA) levels and TAC all were measured. Results: WOMAC scores were improved in both patient groups compared with pre-treatment evaluation (p < 0.025). WOMAC morning stiffness scores were significantly more improved in colchicine group compared with paracetamol group (p > 0.05). TAC was signifcantly increased only in colchicine/paracetamol group. Oxidant parameter MDA levels were significantly decreased in both paracetamol group and colchicine/paracetamol group. CAT, SOD enzyme activities and GSH levels did not change before and after treatment protocols in both patient groups. Conclusion: Both paracetamol 3000 mg/day and 3000 mg paracetamol plus 1,5 gr/day colchicine is effective in the treatment of patients with knee osteoarthritis. But the addition of colchicine to paracetamol produced significantly greater symptomatic benefit than paracetamol alone. Our study also showed that colchicine lowers whole blood MDA which is a lipid peroxidation compound and elevates TAC levels in patients with knee OA. This may show probable disease modifying effect of colchicine in knee OA which require further long period laboratory and radiologic investigations.
Amyand F t Tan m Hakk nda
Aziz Sümer,Ediz Alt?nl?
Medical Journal of Bakirk?y , 2008,
Abstract: Say n edit r, Kas m a layan ve arkada lar taraf ndan Bak rk y T p Dergisi, 2006 tarihli Cilt 2, Say 4, 149-150 sayfalar nda yay nlanm olan “Amyand Hernisi: Olgu Sunumu” ba l kl yaz y okuduk. Bu makale i in ncelikle yazarlara te ekkür ederiz. Bu makaleyle ilgili baz noktalara temas etmek istiyoruz: Makalede; Amyand herni tan m ‘’inguinal herni kesesi i inde akut apandisitin bulunmas durumu’’ olarak tan mlanm t r. Oysa ki; Amyand f t ‘’f t k kesesi i inde apendiks vermiformisin bulunmas ’’ olarak tan mlan r. F - t k kesesi i inde apendiks vermiformis insidans %0.5-%1 olmakla birlikte akut apandisit insidans %0.1’dir. Amyand f t nda tedavi yakla mlar f t k kesesi i inde bulunan apendiksin durumuna ba l d r. Kese i inde bulunan apendiks e er in ame ya da perfore ise apendektomi uygulan r. Kese i inde vermiform apendiks saptanmas halinde apendektomi uygulan p uygulanmamas rutin f t k onar mlar nda enfeksiyon riskinden dolay tart ma konusudur. Geli ebilecek enfeksiyon riskinin oran bilinmemektedir. Ya l hastalarda ameliyat süresinin uzamas , e lik eden di er hastal klar ve bu ya gurubunda apandisit ihtimalinin dü ük olmas nedeniyle profilaktik apendektomi nerilmemektedir. Normal apendiksin f t k kesesi i inde manipülasyonuna ba l apandisitin provake olabilece i bildirilmi tir. Ofili f t k onar m sonras iki hastada apendisit geli ti ini bildirmi tir. Bununla beraber 11 hastada akut apandisit nedeniyle apendektomi uygulad Amyand f t klar nda nüks ya da yara yeri enfeksiyonuna rastlamam t r. Bu nedenle insidental apendektomiyi savunmu tur (1,2). Sayg lar m zla
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