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Biblical Milk Taboos and Scientific Methodology with Ancient Nomenclature  [PDF]
David Iluz, Zohar Amar, Michael Goldberg, Uzi Merin, Yitzhak Katz
Natural Resources (NR) , 2011, DOI: 10.4236/nr.2011.24030
Abstract: Human society and its religions and cultures have laid out numerous guidelines, often involving dietary restrictions (Deut 14:4-5; Lev. 11:2-7). One such set of restrictions still observed by many Jews today relates to the distinction between pure and impure, edible and forbidden mammals (Talmud Bavli, Avoda Zara 35b). The ancient Jewish dietary laws (kashrut) have often perplexed both gentiles and Jews, since they appear to be arbitrary. Here we demonstrate that the separation of pure and impure animals coincides with taxonomic, biochemical, allergenic, and common nutritional properties.
Desensitization Efficacy by Sublingual Immunotherapy of Shrimps Extract in Asthmatic, Rhinitis and Urticaria Allergic Patients  [PDF]
Maged M. Refaat, Mohammed Yousef Attia, Howida Mohamed Saber
Food and Nutrition Sciences (FNS) , 2014, DOI: 10.4236/fns.2014.517183
Abstract: RATIONALE: Crustaceans, such as shrimp, crab, crayfish and lobster, play important role in human nutrition; they also can be important causes of severe acute hypersensitivity reactions. For patients diagnosed with a crustacean allergy, strict avoidance is the only proven therapy, highlighting the need for more specific treatment. Our aim was to evaluate the efficacy and tolerance of sublingual shrimp immunotherapy in Egyptian patients allergic to shrimp. METHODS: This study was intended to help in diagnosis of shrimps allergen in 60 allergic patients (subdivided to 3 groups Urticaria (G1), rhinitis (G2) & asthma (G3)) and evaluate the sublingual immunotherapy by employing skin prick test, specific Immunoglobulin E, Total Immunoglobulin E, Immunoglobulin G, Eosinophilis and Peak Expiratory Flow Rate (PEFR), before and after therapy. Inclusion criteria were a history of shrimp allergy and positive skin prick test to crude shrimp extract from two species [Penaeus semisulcatus and Metapenaeus stebbingi] at allergy and clinical immunology unit, in-Shams Hospitals. They underwent immunotherapy with extract of shrimp species and administered sublingually (SLIT). The measurement of all latter investigations for shrimp allergen on the start and 6 months after immunotherapy, as compared to placebo control, were performed. Results: The clinical response and laboratory improvement of the patients was correlated with their decline in the eosinophils (p < 0.001), total Immunoglobulin E (p < 0.001) and specific Immunoglobulin E test (p < 0.001) and with their increased in PEFR (p < 0.001) and Immunoglobulin G (p < 0.001). This study suggests that the most desenstized responsed group was rhinitis group followed by Urticaria group. Also,The more effective season induce allergy in summer (48.3%) followed by springs (28.3%) and genatic predisposition of allergic diseases was highly accepted in patients had a family history (68%). In conclusion, sublingual immunotherapy for shrimp allergy was safe, simple, uncostly, well tolerated and efficacious, gave a good results especially in the treatment of patients with allergic rhinitis.
A Possible Hypoallergenic Cereal in Wheat Food Allergy and Baker’s Asthma  [PDF]
Alicia Armentia, Sara Martín, Araceli Diaz-Perales, Arantxa Palacín, Leticia Tordesillas, Manuel Herrero, Blanca Martín-Armentia
American Journal of Plant Sciences (AJPS) , 2012, DOI: 10.4236/ajps.2012.312A217
Abstract:

Background: Wheat is a potent allergen source and is one of the causes of baker’s asthma and food allergy. The best strategy for managing food hypersensitivity involves strict avoidance of the trigger. However, wheat is quite difficult to avoid. Several alternative strategies for the treatment of food allergy are under study. Spelt is a possible hypoallergenic crop that may be tried in patients with wheat allergy. Methods: We have evaluated the allergenic IgE hypersensitivity mediated by spelt in wheat allergic patients. Overall, 66 patients who suffered from baker’s asthma or food allergy (45 males and 21 females, mean age 28.6 ± 12.9 years) were included. We have also compared its reactivity with standard- ized extracts from wheat and with purified non-specific lipid transfer proteins from wheat (Tri a 14) and from peach (Pru p 3). Immunodetection with spelt and common bread wheat extracts (Triticum aestivum, cultivar Astral) was per- formed. Fresh wheat and spelt grain extracts were used both for oral and bronchial challenge and skin tests. Specific IgE detection to different cereals was performed using the Immuno CAP System (Phadia, Uppsala, Sweden). The bronchial challenge was positive with wheat Astral in 44 (67%) patients, all of them suffered from asthma. Thirteen (29.54%) of these 44 patients had negative the challenge with spelt. The oral challenge with wheat Astral was positive in 22 (33%) patients with wheat food allergy, and the same test was positive in only in 6 of them with spelt (27.3%). The diagnostic yield (sensitivity, specificity and predictive values) of routine tests

Beef Meat Allergy in Cow’s Milk Allergic Adults  [PDF]
Maged Refaat, Amany Kamal, Mohamed Fares, Eman Ossman, Mohamed Attia, Alsayed Elokda
Food and Nutrition Sciences (FNS) , 2011, DOI: 10.4236/fns.2011.28121
Abstract: Milk has been recognized as a leading cause of food allergy in children; however, studies on cow’s milk allergy (CMA) in adults are scanty. The known cross-reactivity of bovine serum albumin and bovine γ-globulin which are present in both milk and beef is recognized, so that, patients with allergy to cow’s milk are often instructed to avoid beef. Our Objective was to determine the prevalence of allergy to beef meat in adult patients with allergy to cow’s milk. Thirty adults with CMA were included in the study. The diagnosis of cow’s milk and beef allergy was based on a thorough history concerning type of allergic symptoms and its link to the ingestion of milk and beef supported by skin prick test (SPT) with fresh milk and raw beef extracts and by determination of their serum specific IgE by enzyme linked immuosorbant assay (ELISA). Finally, cross reactivity test between milk and meat was performed. Three of 30 patients (10%) evaluated for CMA were found to have symptomatic sensitivity to beef, 2 gave urticarial symptoms and one gave gastrointestinal symptoms. Six patients (20%) had a positive SPT response to beef. On the other hand, beef specific IgE were positive in 18 CMA patients (60%). Concordance of positive specific IgE and SPT to meat was found in only 5 patients (17%). Mean cross reactivity between milk and beef was 31.6 ± 13.1% among studied patients. Patients allergic to milk protein are not necessarily to be allergic to beef, so, elimination of beef from the diet of adults with CMA should not be done except after investigations so as not to lose its nutritional value without benefit.
Efficacy of Oral Antigen Specific Immunotherapy on Desensitization of Some Autoimmune Diseases Associated with Milk Allergy  [PDF]
Azza A. Atef, Mohamed Y. Attia, Osama E. Abdel Aal
Food and Nutrition Sciences (FNS) , 2013, DOI: 10.4236/fns.2013.48104
Abstract:

There are several reports on the prevalence and importance of milk allergens in the induction of allergic diseases, whereas its role in the induction of autoimmune disease was rarely studied. So, the present work aimed to study the diagnosis and the efficacy of oral antigen specific immunotherapy (OAIT) on two groups of autoimmune disease patients namely, rheumatic arthritis (RA), group II, and systemic lupus erythematosus (SLE), group III, who has allergens for milk as an effective treatment option. From the assessment of the data obtained and the clinical outcome of RA and SLE patients after food elimination strategy and milk immunotherapy, it was evident that there were significant reductions (P < 0.001) in the levels of total IgE, specific IgE, Rheumatic factor (R.F), C-reactive protein (C.R.P), Anti-nuclear antibodies (ANA) and anti-double stranded DNA antibodies (Anti-ds DNA) compared to pretreated levels. Moreover, the immunotherapy induced “blocking antibodies” by remarkable highly significant increasing in IgG, phagocytic inhibition test (PIT %), Complement component 3(C3), and Complement component 4 (C4) levels. More improvement was noticed in the SLE as a result of the immunotherapy. Conclusion: milk desensitization is a gained interest and a safe valuable effective treatment of autoimmune conditions in Egypt.

Dust Resulting from Tire Wear and the Risk of Health Hazards  [PDF]
Masakazu Yamashita, Shohei Yamanaka
Journal of Environmental Protection (JEP) , 2013, DOI: 10.4236/jep.2013.46059
Abstract:

The present study examined the effects of air pollutants on people’s health, focusing on dust produced from automobile tires while cars drive on roads. The annual volume of dust resulting from tire wear, calculated based on the number of automobiles registered in Japan, was 1747245.4 m3. To put it simply, this translates to approximately 1.4 times the volume of the Tokyo Dome, a famous Japanese baseball stadium. Particulate substances are categorized into three groups depending on their size, and dust resulting from tire wear is classified into the coarse particle mode along with mold spores, pollen, and dust produced from brake pads. This study examined whether or not tire dust causes health damage similarly to pollen, a particulate substance in the same group. There were 38/cm2 dust particles resulting from tire wear on a busy road in Osaka Prefecture, and this number was larger than that of cedar pollen/cm2 (35), a cause of hay fever, identified in Hokkaido. The results suggest that tire dust may also adversely affect the health of people if any of its constituents has a toxicity or causes allergies.

Estudio de la influencia del consumo de lácteos fermentados en una población de pacientes alérgicos
Luis,D. A. de; Santamaría,A R.; González Sagrado,M.; Izaola,O.; Armentía,A.; Aller,R.;
Anales de Medicina Interna , 2005, DOI: 10.4321/S0212-71992005000200002
Abstract: background: prevalence of allergic diseases has been increased in last years; new alternative therapies have been employed. beneficial effects of probiotics have been described in some pathologies such as tumors, diarrhea, and allergic disease. the aim of our work was to describe nutritional status and influence of probiotic consumption in allergic population. patients and methods: 44 allergic patients were selected, in all patients were recorded; sex, age, place of residence, anthropometric evaluation, dietary questonnaire and allergic variables (rush, blood levels of ig e, and number of crisis in a year). results: 18 patients (40.9%) were females and 26 (59.1%) males with an average age of 24.5 (10.3) years. most of patients (20.5%) are located in percentil p25-50, showing a good nutritional status. 16 patients consumed probiotics (27,1%), with an average of consumption per week 1.79 (3.16) and an average amount per wee (mg-ml) (593.4 (461.9). the number of crisis year was 1.44 (1.8), average value of ig e was 35.68 (31,93) ui/l and rush 10.09 (2.8) mm. patiens with a consumption of probiotics higher than 593 mg/week showed a iow rush diameter (10,12(0,8) mm vs 8.85 (1.1) mm; p < 0.05), without statistical differences in other valiables. conclusion: consumption of probiotics in allergic patients could be benefitial. further studies with more patients and intervention designs will be necesary to analyze this relations.
Latex Allergy - Review Article
Dr. Athma Prasanna
Indian Anaesthetists' Forum , 2005,
Abstract: One of the natures gift to mankind is rubber. The usage of rubber and its products are of daily occurrence in modern life. It is not uncommon to have a regular daily exposure to rubber products from birth in all walks of life.
Latex Allergy - A Case Report
Dr. Athma Prasanna
Indian Anaesthetists' Forum , 2005,
Abstract: The usage of rubber and its products are not uncommon in various walks of life. A continuous exposure or contact may sensitize the human body, causing reactions from mild to fatal. Despite the availability of the literature, medical personnel are still unaware of the implications of the use of latex materials.
"Determination the best cereal substitute for wheat in wheat allergic children "
"Pourpak Z,Mansouri M,Farhoodi A,Ghiasy Esfahany Z "
Tehran University Medical Journal , 2002,
Abstract: Background: Food allergy is one of the most important among other allergic diseases. Although it is less prevalent in adult but in infants it’s prevalence was reported as much as 8 percent. In part, wheat is one of the six main food allergens in infant and in other part there is extensive cross reactivity between the cereals. Therefore the aim of this study is selection of the best food substitute for wheat among other cereals. Materials and Methods: 24 patients with definitive diagnosis of type one hypersensitivity reaction to wheat were entered in this study. Skin prick test and serum specific IgE (Eliza) with 6 members of cereals family (wheat, barley, oat, Rye-Rice & Corn) were performed for them and open food challenge test was also done with three more available of the cereals (corn, Rice, barley) in our food culture and so comparison between allergenicity of wheat flour and wheat bran with skin prick test were done. Results: The Skin prick tests (SPTs) were positive in 66.7 percent for Barley, 100 percent for wheat bran and 80-100 percent for other cereals. The results of specific IgE for wheat, Barley were positive in 94.5 percent, 68 percent, 39 percent of patients respectively and the results for other cereals were positive in less than 11 percent of cases. The results of food challenge test, for barley were positive in 60 percent of cases and for Rice and Corn were negative in all cases. Conclusion: In the base of food challenge test as the gold standard test, the best food substitute for wheat sensitive patient between other cereals, were Corn and Rice respectively. It is important to emphasis that will be needed to perform oral food challenge in hospital with complete emergency equipment before introducing any other cereals as food substitute for wheat, specially Barley.
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