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Search Results: 1 - 10 of 2070 matches for " Alireza Monsef "
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Antibiotic sensitivity pattern of common bacterial pathogens in NICU and neonatal ward in Hamedan province of Iran  [PDF]
Alireza Monsef, Fatemeh Eghbalian
Health (Health) , 2010, DOI: 10.4236/health.2010.26094
Abstract: Bacterial pathogens and drug resistance are different in hospitals of each country. In this study we determined bacterial path- ogens and drug sensitivity in the neonatal ward and neonatal intensive care unit (NICU) in Ekbatan hospital in Hamedan. This cross-sectional descriptive study was done on 1150 hospitalized neonates in neonatal and NICU wards of Ekbatan hospital of the Hamadan university of medical sciences from September 2004 to September 2006. Blood, cerebrospinal fluid (CSF), urine, stool, eye excretion, synovial fluid, umbilical secretion and ascitic fluid were evaluated. Positive cultures were evaluated for antibiotic resistance with disk diffusion test methed. All of the data in questionnaires was analyzed with SPSS 13. Cultures including blood, urine, CSF , stool, eye excretion, synovial fluid, umbilical secretion and ascitic fluid was done in 417 neonates (833 cultures). These cultures were including: urine, 323 cases (38.8%) blood 293 cases (35.2%), CSF 180 cases (21.6%) , stool 17 cases (2%), eye secretion 16 cases (1.9%) and other secretions (synovial, umbilical, etc) 4 cases (0.5%). The cultures were positive in 105 cases (25.2%). 60 male neonates (57.1%) and 45 female neonates (42.9%) were culture positive. The most common microorganisms were E coli 66.7% (70 cases), Klebsiella 10.5% (11 cases). Drug resistance was high in these microorganisms. The most common microorganisms were Ecoli and klebsiella. Drug resistance was high in the isolated microorganisms.
Does conventional phototherapy have any effect on platelet count in full term neonates with indirect hyperbilirubinemia?  [PDF]
Alireza Monsef, Fatemeh Eghbalian
Health (Health) , 2011, DOI: 10.4236/health.2011.312119
Abstract: This study evaluates the platelet count changes in neonates with hyperbillirubinemia who received phototherapy. In this Prospective Descriptive-cross sectional study 144 full term newborns with indirect hyperbillirubinemia who received phototherapy in neonatal ward of Bessat hospital in Hamedan province of Iran were studied from September 2007 to February 2008 for evaluation the effect of phototherapy on platelet count. The platelet had counted by cell counter and it had controlled by slide platelet counting. The data were analyzed using spss version. 13 and compared with paired-samples T test. 58 neonates (40.3%) were boys and 86 (59.7%) were girls. The mean age of neonates was 7.04 +/– 5.49 days (2 - 29 days). The mean (± SD) platelet counts were 287833.3 + 92332.4 before and 299444.4 + 98565.2 after phototherapy. Analysis of data with paired T test showed significant difference in platelet count before and after phototherapy. Mean platelet count after phototherapy was higher than that before treatment. The study had propounded that mean platelet count increased with extended mean phototherapy time. This study had propounded this hypothesis that phototherapy in full term icteric newborns leads to increased platelet count. It may be due to accelerated platelet turnover in peripheral microvasculature with adequate platelet reserve.
Evaluation of Diagnostic Value of Procalcitonin as a Marker of Neonatal Bacterial Infections
Alireza Monsef,Fatemeh Eghbalian
Iranian Journal of Pediatrics , 2012,
Abstract: Objective: This study tried to assess sensitivity, specificity, positive and negative predictive value of procalcitonin for diagnosis of neonatal bacterial infections.Methods: This prospective cross sectional study was carried out during an 18-month period in NICU and neonatal wards of Besat Hospital in Hamedan province, Iran. 39 symptomatic infants with clinical and laboratory findings in favor of bacterial infection with a positive blood, CSF, and/or supra pubic urine cultureentered the study; 32 newborns without any bacterial infection served as control group. Quantitative procalcitonin level ≥0.5 ng/ml was accepted as pathological. Finally sensitivity, specificity, positive (PPV) and negative predictive value (NPV) were calculated for procalcitonin test.Findings: 20 blood cultures, 17 urine cultures and 8 CSF cultures were positive. Sensitivity, specificity, PPV and NPV for procalcitonin test was 76.9%, 100%, 100% and 78% respectively. Diagnostic value of procalcitonin test in accordance with blood culture for mentioned items was 85%, 100%, 100% and 91.4%respectively. Its diagnostic value according to urine culture was: sensitivity 70.6%, specificity 100%, PPV 100% and NPV 86.4%, and according to CSF culture was: sensitivity 75%, specificity 100%, PPV 100% and NPV 94.1% respectively.Conclusion: The results show that the procalcitonin test has high sensitivity, specificity, PPV and NPV for diagnosis of neonatal infections.
Urinary Tract and Other Associated Anomalies in Newborns With Esophageal Atresia
Fatemeh Eghbalian,Alireza Monsef,Seyed Habibollah Mousavi-Bahar
Urology Journal , 2009,
Abstract: Esophageal atresia is often associated with other anomalies. Hereditary and environmental factors may influence the incidence of associated anomalies, particularly of the urogenital system. We had 63 neonates with esophageal atresia admitted to 2 centers in Hamadan, Iran, from 2002 to 2008. They were 38 girls (60.3%) and 25 boy (39.7%). Tracheoesophageal fistula was present in 54 neonates (85.7%), and other associated anomalies in 10 (15.9%). Cardiac anomalies were found in 7 neonates; anorectal anomalies, in 4; urinary tract anomalies, in 2; and limb anomaly, in 1. Urinary tract anomalies (3.2%) were bilateral polycystic kidney in 1 neonate and unilateral hydronephrosis due to ureteropelvic junction obstruction in another. Both neonates with urinary tract anomalies were female and both had tracheoesophageal fistula, as well. Many of the associated congenital abnormalities influence the management protocol of esophageal atresia, and therefore, should be detected as soon as possible after birth.
Oral Fluid Antibody Detection in the Diagnosis of Gastric Helicobacter pylori Infection
Behzad Hooshm,Alireza Monsef,Mohammad Amirmadglesi,Mani Kashani
Iranian Journal Of Allergy, Asthma and Immunology , 2004,
Abstract: The aim of this study was to evaluate an enzyme - linked immunosorbent assay (ELISA) for the detection of anti - helicobacter pylori (H. pylori) specific IgG antibodies in specimens of oral fluid.All subjects over the age 18 years undergoing endoscopy for any reason were asked to participate in the study. Two groups of 44 patients in each were selected as HP+ and HP-. At the same time, 5 milliliters of unstimulated saliva was collected from these patients, and the antibody titration against H.P. was evaluated by “ELISA” method.In overall, the level of salivary antibody in H.P+ group was significantly more than those in H.P- group (P<0/001). In the best cut - off, sensitivity and specificity obtained in this test were respectively 88.6% and 81.8% and positive predictive and negative predictive values were determined as 83% and 87.8%, respectively. Positive Likelihood Ratio and negative likelihood ratio were 6.8 and -0/083, respectively.Oral fluid ELISA is relatively a comfortable, fast and noninvasive test for diagnosis of H. pylori infection.
Assessment of the Nutritional Status of the Egyptian Patient with End Stage Liver Disease Prior to Liver Transplantation  [PDF]
Waheed A. Monsef, Ibrahim Mostafa, Doaa Zaky
Open Journal of Gastroenterology (OJGas) , 2014, DOI: 10.4236/ojgas.2014.44024
Abstract: Background and Aim: Patients with advanced liver disease have several risk factors to develop nutritional deficiencies. Accurate nutritional assessment is a real challenge because many of the traditionally measured parameters of nutritional status vary with severity of liver disease independently of nutritional status. The objective of this study was to assess the Egyptian patients with end stage liver disease and to compare different tools used to assess their nutritional status. Patients and Methods: 60 patients were nutritionally assessed by SGA, RFH-SGA anthropometry, handgrip dynamometry and biochemical tests. Clinical variables were cross analyzed with the nutritional assessment methods. Results: Malnutrition ranged from 7% by BMI and 100% by SGA. Agreement among all the methods was low compared with the SGA. Correlation between Malnutrition prevalence and the severity of liver disease was verified using Child-Pugh score more than MELD score. Conclusion: Malnutrition is highly prevalent among the Egyptian patients with end stage liver disease prior to liver transplantation. Although the diagnosis of nutritional status is not easy among this category of patients, it varied according to the method used. Nutritional support should be an important part of the preoperative care of liver transplantation patients.
Two Cases of Appendiceal Intussusception: A Rare Diagnostic Pitfall in Colonoscopy
Hassan Seddik,Monsef Rabhi
Diagnostic and Therapeutic Endoscopy , 2011, DOI: 10.1155/2011/198984
Abstract: Partially or completely invaginated appendix mistaken for a polyp during colonoscopy and leading to intussusception is a rare situation. This paper describes our experience with two cases of appendiceal intussusception. In the first case, there was no underlying ileocecal abnormality, and, in the second case, histologic examination of the resected appendix and cecum revealed widespread foci of angiodysplasia, and this was thought to be the basis for the intussusception. The authors present reviews of the literature concerning clinical features and associated conditions and emphasize that failure to recognize this condition may result in unexpected complications such as consequent peritonitis in case of endoscopic removal. 1. Introduction Intussusception of the appendix is an extremely rare condition. It affects all ages but is usually associated with males in the first decade [1]. Despite its rarity, endoscopists must consider appendiceal intussusception in the differential diagnosis when a “polyp” is seen on colonoscopy in order to avoid a consequent peritonitis in case of endoscopic removal. We report here two cases: the first was fortuitously discovered on colonoscopy, and the second was responsible for lower- gastrointestinal-tract bleeding. We insist on morphological characteristics as to permit an early recognition and treatment of this condition. 2. Case Report 2.1. Case 1 A 48-year-old man with several years history of abdominal pain and transit disturbances was admitted to our hospital for further investigations. Physical examination and laboratory data were within normal limits. Colonoscopy revealed a sessile, dimpled 20?mm cecal polyp (Figure 1) covered with macroscopically normal colonic mucosa. The appendiceal orifice in the cecum was not seen. Biopsies were performed, and, 12 hours after, the patient experienced fever and shivering. Clinical examination of the abdomen and plain abdominal roentgenogram were normal. Complete recovery was obtained after broad spectrum antibiotherapy. On histology, the polyp was found to be normal inverted appendiceal wall. Abdominal ultrasound and CT scan showed a partially invaginated appendix into the cecal cavity without any evidence of tumoral process. Regular ultrasound examinations during two years showed an unchanged aspect of the inverted appendix Figure 1: Sessile, dimpled 20?mm polypoid mass in the cecum. Colonoscopic image. 2.2. Case 2 A 65-year-old man was admitted to our hospital with a six-month history of melena with transfusion requirement. Hemogram showed hypochromic microcytic anemia
Endogenous Retroviruses: Thierry Heidmann wins the 2009 Retrovirology prize
Ali Saib, Monsef Benkirane
Retrovirology , 2009, DOI: 10.1186/1742-4690-6-108
Abstract: In 2005, thanks to the generosity of the Ming K. Jeang Foundation, the Retrovirology prize was inaugurated. A goal of the Retrovirology Prize is to identify an outstanding mid-career scientist who is close to the peak of his/her productivity and who is expected to have many future years of high achievement. Previous winners of the Retrovirology Prize include Stephen Goff [1], Joseph Sodroski [2], Karen Beemon [3] and Ben Berkhout [4].For 2009, the Editors of Retrovirology have selected Thierry Heidmann (Figure 1) as the recipient of the Retrovirology Prize.TH heads a CNRS laboratory at Université Paris-Sud and Institut Gustave Roussy in Villejuif, in the southern suburbs of Paris. With a strong background in physics and mathematics, he was interested in the early 1980's in linking these disciplines of science with biology, more precisely with neurobiology and the science of complex neuronal networks. To fulfil his aspiration, Thierry entered Jean-Pierre Changeux's lab at the Pasteur Institute to start a PhD on the newly discovered acetylcholine receptor. This exciting experience led Thierry to turn to more applied science, following a profound will to slowly but surely shift from studying the physical sciences to studying the biological sciences! After his PhD, Thierry focused on transposable elements and retrotransposons. The question he asked at that time was simple: how to be able to monitor the transposition of these mobile elements in a mammal where genetic approaches to detect transposition were both poorly efficient and time consuming. He then decided to devise a system that could detect retrotransposition of any element whose mobilization includes a reverse transcription step, no matter where the reverse transcribed, transposed element would target and integrate. This search resulted in 1988 in the generation of the first indicator gene for retrotransposition. This was his first step in the field, but a decisive one. Since then, his laboratory has focused on
Home Automation Device Protocol (HADP): A Protocol Standard for Unified Device Interactions  [PDF]
Thomas Gonnot, Won-Jae Yi, Ehsan Monsef, Jafar Saniie
Advances in Internet of Things (AIT) , 2015, DOI: 10.4236/ait.2015.54005
Abstract: Daily activities have become more efficient and convenient with home automation. There are many different home automation devices in the market for consumers to enjoy their home for being smarter, resourceful, and remotely accessible. However, current home automation protocols lack extensibility and compatibility. In this paper, we propose a protocol standard for home automation system called Home Automation Device Protocol (HADP). This protocol standard aims for the interoperability of home automation devices across different platforms. Based on the IFTTT (IF-This-Then-That) model, we define a set of device communication protocols where devices’ triggers and actions are combined to generate and manage interactions through a central node. The proposed protocol standard offers low power consumption and low bandwidth requirements using the minimum data packets to trigger an action on a home automation device. The protocol supports various communication mediums such as Wi-Fi, Bluetooth 4.2, ZigBee IP, 6LoWPAN, IEEE 802.15.4 standards, and Ethernet orany network layer supporting IPv6 protocol.
An Actual Survey of Dimensionality Reduction  [PDF]
Alireza Sarveniazi
American Journal of Computational Mathematics (AJCM) , 2014, DOI: 10.4236/ajcm.2014.42006
Abstract:

Dimension reduction is defined as the processes of projecting high-dimensional data to a much lower-dimensional space. Dimension reduction methods variously applied in regression, classification, feature analysis and visualization. In this paper, we review in details the last and most new version of methods that extensively developed in the past decade.

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